Published in Am J Physiol Cell Physiol on April 27, 2005
Regulation of M(Kv7.2/7.3) channels in neurons by PIP(2) and products of PIP(2) hydrolysis: significance for receptor-mediated inhibition. J Physiol (2007) 1.24
Receptor-specific inhibition of GABAB-activated K+ currents by muscarinic and metabotropic glutamate receptors in immature rat hippocampus. J Physiol (2007) 0.99
Decrease in PIP(2) channel interactions is the final common mechanism involved in PKC- and arachidonic acid-mediated inhibitions of GABA(B)-activated K+ current. J Physiol (2007) 0.92
Differential phosphoinositide binding to components of the G protein-gated K+ channel. J Membr Biol (2006) 0.86
A genetically encoded tool kit for manipulating and monitoring membrane phosphatidylinositol 4,5-bisphosphate in intact cells. PLoS One (2011) 0.81
Cholesterol inhibits M-type K+ channels via protein kinase C-dependent phosphorylation in sympathetic neurons. J Biol Chem (2010) 0.81
GIRK channels: hierarchy of control. Focus on "PKC-delta sensitizes Kir3.1/3.2 channels to changes in membrane phospholipid levels after M3 receptor activation in HEK-293 cells". Am J Physiol Cell Physiol (2005) 0.80
Overexpression of diacylglycerol kinase η enhances Gαq-coupled G protein-coupled receptor signaling. Mol Pharmacol (2014) 0.78
Short-term desensitization of muscarinic K+ current in the heart. Biophys J (2013) 0.77
A Critical Gating Switch at a Modulatory Site in Neuronal Kir3 Channels. J Neurosci (2015) 0.75
Regulation of mitochondrial structure and function by the F1Fo-ATPase inhibitor protein, IF1. Cell Metab (2008) 2.22
Differential effects of stable prostacyclin analogs on smooth muscle proliferation and cyclic AMP generation in human pulmonary artery. Am J Respir Cell Mol Biol (2002) 2.06
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Res (2013) 1.92
Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells. Proc Natl Acad Sci U S A (2005) 1.91
Retracted The large-conductance Ca2+-activated K+ channel is essential for innate immunity. Nature (2004) 1.85
Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature. BMC Physiol (2005) 1.53
In-center nocturnal hemodialysis: another option in the management of chronic kidney disease. Clin J Am Soc Nephrol (2009) 1.39
In situ maleimide bridging of disulfides and a new approach to protein PEGylation. Bioconjug Chem (2011) 1.33
A systematic review of factors influencing decision-making in adults living with chronic kidney disease. Patient Educ Couns (2009) 1.32
Lipid rafts determine efficiency of NADPH oxidase activation in neutrophils. FEBS Lett (2003) 1.28
Regulation of M(Kv7.2/7.3) channels in neurons by PIP(2) and products of PIP(2) hydrolysis: significance for receptor-mediated inhibition. J Physiol (2007) 1.24
Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study. Eur Heart J (2012) 1.24
Monitoring changes in membrane phosphatidylinositol 4,5-bisphosphate in living cells using a domain from the transcription factor tubby. J Physiol (2008) 1.19
Regulators of G-protein signaling form a quaternary complex with the agonist, receptor, and G-protein. A novel explanation for the acceleration of signaling activation kinetics. J Biol Chem (2005) 1.18
The molecular composition of K(ATP) channels in human pulmonary artery smooth muscle cells and their modulation by growth. Am J Respir Cell Mol Biol (2002) 1.12
Abnormal KCNQ1 trafficking influences disease pathogenesis in hereditary long QT syndromes (LQT1). Cardiovasc Res (2005) 1.11
Multisite phosphorylation mechanism for protein kinase A activation of the smooth muscle ATP-sensitive K+ channel. Circ Res (2004) 1.10
Mechanism of hERG K+ channel blockade by the fluoroquinolone antibiotic moxifloxacin. Br J Pharmacol (2006) 1.07
Assembly limits the pharmacological complexity of ATP-sensitive potassium channels. J Biol Chem (2002) 1.01
UTP induces osteopontin expression through a coordinate action of NFkappaB, activator protein-1, and upstream stimulatory factor in arterial smooth muscle cells. J Biol Chem (2004) 1.00
PIP(2)-dependent inhibition of M-type (Kv7.2/7.3) potassium channels: direct on-line assessment of PIP(2) depletion by Gq-coupled receptors in single living neurons. Pflugers Arch (2007) 1.00
Characterization of a binding site for anionic phospholipids on KCNQ1. J Biol Chem (2010) 0.98
In vitro and in vivo cardiomyogenic differentiation of amniotic fluid stem cells. Stem Cell Rev (2011) 0.97
Essential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variability. PLoS One (2013) 0.95
The Role of Inhibitory G Proteins and Regulators of G Protein Signaling in the in vivo Control of Heart Rate and Predisposition to Cardiac Arrhythmias. Front Physiol (2012) 0.95
Genetics of smoking and depression. Hum Genet (2012) 0.95
IP receptor-dependent activation of PPARgamma by stable prostacyclin analogues. Biochem Biophys Res Commun (2007) 0.95
The role of inhibitory heterotrimeric G proteins in the control of in vivo heart rate dynamics. Am J Physiol Regul Integr Comp Physiol (2008) 0.95
Investigating dynamic protocol-dependence of hERG potassium channel inhibition at 37 degrees C: Cisapride versus dofetilide. J Pharmacol Toxicol Methods (2010) 0.95
Epistatic rescue of Nkx2.5 adult cardiac conduction disease phenotypes by prospero-related homeobox protein 1 and HDAC3. Circ Res (2012) 0.95
NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system. Dev Biol (2012) 0.94
The role of ATP-sensitive potassium channels in cellular function and protection in the cardiovascular system. Br J Pharmacol (2014) 0.94
HL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes. Pflugers Arch (2010) 0.93
The dynamics of formation and action of the ternary complex revealed in living cells using a G-protein-gated K+ channel as a biosensor. J Biol Chem (2003) 0.93
Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-one analogues as inhibitors of the annexin A2-S100A10 protein interaction. J Med Chem (2011) 0.92
Absence of the inhibitory G-protein Galphai2 predisposes to ventricular cardiac arrhythmia. Circ Arrhythm Electrophysiol (2010) 0.90
Overexpression of the transcription factor Hand1 causes predisposition towards arrhythmia in mice. J Mol Cell Cardiol (2009) 0.90
Protein interactions between surface annexin A2 and S100A10 mediate adhesion of breast cancer cells to microvascular endothelial cells. FEBS Lett (2013) 0.90
Complex ABCC8 DNA variations in congenital hyperinsulinism: lessons from functional studies. Clin Endocrinol (Oxf) (2007) 0.89
The intracellular localization and function of the ATP-sensitive K+ channel subunit Kir6.1. J Membr Biol (2010) 0.89
Agonist unbinding from receptor dictates the nature of deactivation kinetics of G protein-gated K+ channels. Proc Natl Acad Sci U S A (2003) 0.89
Structural requirements of membrane phospholipids for M-type potassium channel activation and binding. J Biol Chem (2012) 0.89
Direct observation of individual KCNQ1 potassium channels reveals their distinctive diffusive behavior. J Biol Chem (2009) 0.89
Do anionic phospholipids serve as cofactors or second messengers for the regulation of activity of cloned ATP-sensitive K+ channels? Circ Res (2003) 0.88
Erythromycin block of the HERG K+ channel: accessibility to F656 and Y652. Biochem Biophys Res Commun (2006) 0.88
Regulation of the ATP-sensitive potassium channel subunit, Kir6.2, by a Ca2+-dependent protein kinase C. J Biol Chem (2011) 0.87
Rapid desensitization of G protein-gated inwardly rectifying K(+) currents is determined by G protein cycle. Am J Physiol Cell Physiol (2004) 0.87
A novel signaling pathway: fibroblast nicotinic receptor alpha1 binds urokinase and promotes renal fibrosis. J Biol Chem (2009) 0.87
Annexin A2 complexes with S100 proteins: structure, function and pharmacological manipulation. Br J Pharmacol (2014) 0.87
Differential phosphoinositide binding to components of the G protein-gated K+ channel. J Membr Biol (2006) 0.86
A novel strategy to engineer functional fluorescent inhibitory G-protein alpha subunits. J Biol Chem (2002) 0.86
hERG K+ channel blockade by the antipsychotic drug thioridazine: An obligatory role for the S6 helix residue F656. Biochem Biophys Res Commun (2006) 0.85
N-Formyl peptide receptor subtypes in human neutrophils activate L-plastin phosphorylation through different signal transduction intermediates. Biochem J (2004) 0.85
Readthrough of long-QT syndrome type 1 nonsense mutations rescues function but alters the biophysical properties of the channel. Biochem J (2012) 0.85
Mechanisms of disease pathogenesis in long QT syndrome type 5. Am J Physiol Cell Physiol (2009) 0.84
A Cy5-labeled S100A10 tracer used to identify inhibitors of the protein interaction with annexin A2. Assay Drug Dev Technol (2010) 0.84
Different molecular sites of action for the KATP channel inhibitors, PNU-99963 and PNU-37883A. Br J Pharmacol (2003) 0.84
Strategies to identify ion channel modulators: current and novel approaches to target neuropathic pain. Drug Discov Today (2004) 0.84
Three-dimensional pharmacophore design and biochemical screening identifies substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction. ChemMedChem (2012) 0.83
The genetic basis of melanism in the gray squirrel (Sciurus carolinensis). J Hered (2009) 0.83
A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P₂. Pflugers Arch (2013) 0.83
Differences in the mechanism of metabolic regulation of ATP-sensitive K+ channels containing Kir6.1 and Kir6.2 subunits. Cardiovasc Res (2008) 0.83
Sarcolemmal cardiac K(ATP) channels as a target for the cardioprotective effects of the fluorine-containing pinacidil analogue, flocalin. Br J Pharmacol (2011) 0.83
Determination of phosphoinositide binding to K(+) channel subunits using a protein-lipid overlay assay. Methods Mol Biol (2008) 0.83
Involvement of protein kinase D in Fc gamma-receptor activation of the NADPH oxidase in neutrophils. Biochem J (2002) 0.82
The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking. Eur J Biochem (2002) 0.81
Subcellular localisation of the p40phox component of NADPH oxidase involves direct interactions between the Phox homology domain and F-actin. Int J Biochem Cell Biol (2010) 0.80
Functional expression of inward rectifier potassium channels in cultured human pulmonary smooth muscle cells: evidence for a major role of Kir2.4 subunits. J Membr Biol (2007) 0.80
Connexins in the heart. Cell Tissue Res (2014) 0.79
Phenformin has a direct inhibitory effect on the ATP-sensitive potassium channel. Eur J Pharmacol (2010) 0.79
Bromo- and thiomaleimides as a new class of thiol-mediated fluorescence 'turn-on' reagents. Org Biomol Chem (2014) 0.79
A patient-focused approach to thrombolytic use in the management of catheter malfunction. Semin Dial (2006) 0.79
Syntaxin-1A actions on sulfonylurea receptor 2A can block acidic pH-induced cardiac K(ATP) channel activation. J Biol Chem (2006) 0.78
The design, synthesis and pharmacological characterization of novel β₂-adrenoceptor antagonists. Br J Pharmacol (2011) 0.78
Protein kinase C as an effector of lipid-derived second messengers. Methods Mol Biol (2009) 0.77
The impact of recent advances in genetics in understanding disease mechanisms underlying the long QT syndromes. Biol Chem (2016) 0.77
The in vivo regulation of heart rate in the murine sinoatrial node by stimulatory and inhibitory heterotrimeric G proteins. Am J Physiol Regul Integr Comp Physiol (2013) 0.77
Do caveolae have a role in the fidelity and dynamics of receptor activation of G-protein-gated inwardly rectifying potassium channels? J Biol Chem (2010) 0.77
Exploring the impact of a decision support intervention on vascular access decisions in chronic hemodialysis patients: study protocol. BMC Nephrol (2011) 0.76
An efficient asymmetric synthesis of the potent beta-blocker ICI-118,551 allows the determination of enantiomer dependency on biological activity. Chem Commun (Camb) (2010) 0.76
A dual optical and nuclear imaging reagent for peptide labelling via disulfide bridging. Org Biomol Chem (2015) 0.76
Photochemically re-bridging disulfide bonds and the discovery of a thiomaleimide mediated photodecarboxylation of C-terminal cysteines. Org Biomol Chem (2015) 0.75
ATP-sensitive potassium channels and vascular function. Channels (Austin) (2015) 0.75
Pseudohyponatraemia due to L-asparaginase-associated dyslipidaemia in T-cell lymphoblastic lymphoma. BMJ Case Rep (2014) 0.75
Revitalization. CANNT J (2014) 0.75
Using total internal reflection fluorescence microscopy to observe ion channel trafficking and assembly. Methods Mol Biol (2013) 0.75
The Canadian Organ Replacement Register: From data submission to final reports. CANNT J (1) 0.75
Are you SURE about your vascular access? Exploring factors influencing vascular access decisions with chronic hemodialysis patients and their nurses. CANNT J (1) 0.75
Remember me: a permanent memorial created through the art of quilting. CANNT J (2006) 0.75
A new year--a new approach. CANNT J (2013) 0.75
Adult Outcomes After Newborn Respiratory Failure Treated With Extracorporeal Membrane Oxygenation. Pediatr Crit Care Med (2016) 0.75
The Canadian Organ Replacement Register: Nursing's important contribution. CANNT J (2016) 0.75