Published in J Virol on February 01, 2005
Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization. J Virol (2010) 1.92
Novel approaches to inhibiting HIV-1 replication. Antiviral Res (2009) 1.48
A mutation in alpha helix 3 of CA renders human immunodeficiency virus type 1 cyclosporin A resistant and dependent: rescue by a second-site substitution in a distal region of CA. J Virol (2007) 1.28
Virus maturation as a new HIV-1 therapeutic target. Expert Opin Ther Targets (2009) 1.13
HIV-1 uncoating: connection to nuclear entry and regulation by host proteins. Virology (2014) 1.12
Mutational analysis of the N-terminal domain of Moloney murine leukemia virus capsid protein. J Virol (2007) 1.12
Role of human immunodeficiency virus type 1 integrase in uncoating of the viral core. J Virol (2010) 1.07
Second-site compensatory mutations of HIV-1 capsid mutations. J Virol (2011) 1.04
Characterization of the in vitro HIV-1 capsid assembly pathway. J Mol Biol (2009) 1.04
Isolated HIV-1 core is active for reverse transcription. Retrovirology (2007) 1.04
Analysis of human immunodeficiency virus matrix domain replacements. Virology (2007) 1.01
Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain. Retrovirology (2011) 0.99
The interdomain linker region of HIV-1 capsid protein is a critical determinant of proper core assembly and stability. Virology (2011) 0.99
Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid. Bioorg Med Chem (2010) 0.92
The NTD-CTD intersubunit interface plays a critical role in assembly and stabilization of the HIV-1 capsid. Retrovirology (2013) 0.92
New approaches for antiviral targeting of HIV assembly. J Mol Biol (2011) 0.92
High-throughput profiling of point mutations across the HIV-1 genome. Retrovirology (2014) 0.87
Analysis of HIV-1 Gag protein interactions via biotin ligase tagging. J Virol (2015) 0.86
A small loop in the capsid protein of Moloney murine leukemia virus controls assembly of spherical cores. J Virol (2006) 0.82
Incorporation of human immunodeficiency virus type 1 reverse transcriptase into virus-like particles. J Virol (2007) 0.82
Slower uncoating is associated with impaired replicative capability of simian-tropic HIV-1. PLoS One (2013) 0.81
A second-site suppressor significantly improves the defective phenotype imposed by mutation of an aromatic residue in the N-terminal domain of the HIV-1 capsid protein. Virology (2006) 0.79
Second site reversion of a mutation near the amino terminus of the HIV-1 capsid protein. Virology (2013) 0.79
RRE-dependent HIV-1 Env RNA effects on Gag protein expression, assembly and release. Virology (2014) 0.78
Sultam thiourea inhibition of West Nile virus. Antimicrob Agents Chemother (2007) 0.78
Analysis of the N-terminal region of the murine leukemia virus nucleocapsid protein. Virus Res (2010) 0.77
Contributions of Charged Residues in Structurally Dynamic Capsid Surface Loops to Rous Sarcoma Virus Assembly. J Virol (2016) 0.76
Forced Complementation between Subgenomic RNAs: Does Human Immunodeficiency Type 1 Virus Reverse Transcription Occur in Viral Core, Cytoplasm, or Early Endosome? J AIDS Immune Res (2015) 0.75
Inhibition of HIV-1 Maturation via Small-Molecule Targeting of the Amino-Terminal Domain in the Viral Capsid Protein. J Virol (2017) 0.75
The matrix protein of human immunodeficiency virus is cleaved and packed into virion cores. Dokl Biol Sci (2006) 0.75
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem (1987) 59.79
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature (2004) 17.56
Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology (1995) 14.30
Specific incorporation of cyclophilin A into HIV-1 virions. Nature (1994) 7.13
Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid. Cell (1996) 6.74
Assembly and analysis of conical models for the HIV-1 core. Science (1999) 6.35
Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein. Science (1997) 6.10
Image reconstructions of helical assemblies of the HIV-1 CA protein. Nature (2000) 5.60
A sensitive and specific enzyme-based assay detecting HIV-1 virion fusion in primary T lymphocytes. Nat Biotechnol (2002) 5.49
Structure of the amino-terminal core domain of the HIV-1 capsid protein. Science (1996) 5.44
Formation of a human immunodeficiency virus type 1 core of optimal stability is crucial for viral replication. J Virol (2002) 5.20
Restriction of lentivirus in monkeys. Proc Natl Acad Sci U S A (2002) 5.02
Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism. Proc Natl Acad Sci U S A (2002) 4.66
A dominant block to HIV-1 replication at reverse transcription in simian cells. Proc Natl Acad Sci U S A (2002) 4.52
Functional surfaces of the human immunodeficiency virus type 1 capsid protein. J Virol (2003) 4.47
Proteolytic refolding of the HIV-1 capsid protein amino-terminus facilitates viral core assembly. EMBO J (1998) 4.46
Restriction of multiple divergent retroviruses by Lv1 and Ref1. EMBO J (2003) 4.19
Quantitation of transcription and clonal selection of single living cells with beta-lactamase as reporter. Science (1998) 4.15
Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription. J Virol (1996) 4.15
Crystal structure of dimeric HIV-1 capsid protein. Nat Struct Biol (1996) 3.93
Assembly, processing, and infectivity of human immunodeficiency virus type 1 gag mutants. J Virol (1993) 3.75
Structure of the N-terminal 283-residue fragment of the immature HIV-1 Gag polyprotein. Nat Struct Biol (2002) 3.54
Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis. J Virol (1994) 3.48
Functional domains of the capsid protein of human immunodeficiency virus type 1. J Virol (1994) 3.47
Assembly properties of the human immunodeficiency virus type 1 CA protein. J Virol (2004) 3.09
A conformational switch controlling HIV-1 morphogenesis. EMBO J (2000) 2.86
Biochemical and structural analysis of isolated mature cores of human immunodeficiency virus type 1. J Virol (2000) 2.80
Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity. J Virol (1995) 2.56
Conditional infectivity of a human immunodeficiency virus matrix domain deletion mutant. J Virol (1993) 2.42
Human immunodeficiency virus type 1 N-terminal capsid mutants that exhibit aberrant core morphology and are blocked in initiation of reverse transcription in infected cells. J Virol (2001) 2.17
Fullerene-like organization of HIV gag-protein shell in virus-like particles produced by recombinant baculovirus. Virology (1994) 1.95
Structural analysis of human immunodeficiency virus type 1 Gag protein interactions, using cysteine-specific reagents. J Virol (1996) 1.55
Hantavirus nucleocapsid protein coiled-coil domains. J Biol Chem (2002) 1.52
HIV-1 capsid protein forms spherical (immature-like) and tubular (mature-like) particles in vitro: structure switching by pH-induced conformational changes. Biophys J (2001) 1.32
Cells with high cyclophilin A content support replication of human immunodeficiency virus type 1 Gag mutants with decreased ability to incorporate cyclophilin A. J Virol (1998) 1.29
Organization of HIV-1 capsid proteins on a lipid monolayer. J Biol Chem (1998) 1.28
Structural interactions between retroviral Gag proteins examined by cysteine cross-linking. J Virol (1995) 1.25
Human immunodeficiency virus type 1 N-terminal capsid mutants containing cores with abnormally high levels of capsid protein and virtually no reverse transcriptase. J Virol (2003) 1.24
Further evidence for hexagonal organization of HIV gag protein in prebudding assemblies and immature virus-like particles. J Struct Biol (1998) 1.17
Crosslink analysis of N-terminal, C-terminal, and N/B determining regions of the Moloney murine leukemia virus capsid protein. Virology (2000) 0.93
Analysis of the retrovirus capsid interdomain linker region. Virology (2003) 0.89
Effects of gag mutations on human immunodeficiency virus type 1 particle assembly, processing, and cyclophilin A incorporation. J Med Virol (2002) 0.82
Antiviral inhibition of the HIV-1 capsid protein. J Mol Biol (2003) 2.27
Analysis of human immunodeficiency virus type 1 matrix binding to membranes and nucleic acids. J Virol (2009) 1.55
Hantavirus nucleocapsid protein coiled-coil domains. J Biol Chem (2002) 1.52
Retrovirus capsid protein assembly arrangements. J Mol Biol (2003) 1.40
Analysis of Rous sarcoma virus capsid protein variants assembled on lipid monolayers. J Mol Biol (2002) 1.29
HIV-1 Nef assembles a Src family kinase-ZAP-70/Syk-PI3K cascade to downregulate cell-surface MHC-I. Cell Host Microbe (2007) 1.26
Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer. J Virol (2006) 1.17
HIV-1 matrix organizes as a hexamer of trimers on membranes containing phosphatidylinositol-(4,5)-bisphosphate. Virology (2009) 1.16
Assembly of human immunodeficiency virus precursor gag proteins. J Biol Chem (2005) 1.11
Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action. Mol Biol Cell (2010) 1.10
Analysis of human immunodeficiency virus type 1 Gag dimerization-induced assembly. J Virol (2005) 1.08
HIV-1 matrix protein binding to RNA. J Mol Biol (2011) 1.07
Second-site compensatory mutations of HIV-1 capsid mutations. J Virol (2011) 1.04
Analysis of human immunodeficiency virus matrix domain replacements. Virology (2007) 1.01
Hexagonal organization of Moloney murine leukemia virus capsid proteins. Virology (2002) 0.98
Assessment of contrast gain signature in inferred magnocellular and parvocellular pathways in patients with glaucoma. Vision Res (2008) 0.96
Structure-specific recognition protein 1 facilitates microtubule growth and bundling required for mitosis. Mol Cell Biol (2009) 0.93
Analysis of the retrovirus capsid interdomain linker region. Virology (2003) 0.89
Analysis of small molecule ligands targeting the HIV-1 matrix protein-RNA binding site. J Biol Chem (2012) 0.84
Determinants of the HIV-1 core assembly pathway. Virology (2011) 0.80
Second site reversion of a mutation near the amino terminus of the HIV-1 capsid protein. Virology (2013) 0.79
EMXtalOrg: an EM tilt data organization and processing system. Ultramicroscopy (2002) 0.78
Analysis of the N-terminal region of the murine leukemia virus nucleocapsid protein. Virus Res (2010) 0.77
Mutations affecting cleavage at the p10-capsid protease cleavage site block Rous sarcoma virus replication. Retrovirology (2005) 0.76