Published in J Virol on May 01, 2003
Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. J Virol (2006) 6.30
An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein. Cell Host Microbe (2007) 4.17
X-ray structures of the hexameric building block of the HIV capsid. Cell (2009) 4.08
The structural biology of HIV assembly. Curr Opin Struct Biol (2008) 3.71
HIV-1 assembly, budding, and maturation. Cold Spring Harb Perspect Med (2012) 3.17
Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells. EMBO J (2007) 3.17
Assembly properties of the human immunodeficiency virus type 1 CA protein. J Virol (2004) 3.09
Extraepitopic compensatory substitutions partially restore fitness to simian immunodeficiency virus variants that escape from an immunodominant cytotoxic-T-lymphocyte response. J Virol (2004) 2.71
Evidence for a functional link between uncoating of the human immunodeficiency virus type 1 core and nuclear import of the viral preintegration complex. J Virol (2006) 2.57
Atomic-level modelling of the HIV capsid. Nature (2011) 2.41
Species-specific tropism determinants in the human immunodeficiency virus type 1 capsid. J Virol (2004) 2.37
Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response. PLoS Pathog (2009) 2.36
Real-time visualization of HIV-1 GAG trafficking in infected macrophages. PLoS Pathog (2008) 2.32
Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function. Cell (2009) 2.32
Simian-human immunodeficiency virus escape from cytotoxic T-lymphocyte recognition at a structurally constrained epitope. J Virol (2003) 2.15
Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A. Proc Natl Acad Sci U S A (2005) 2.12
Complementary assays reveal a relationship between HIV-1 uncoating and reverse transcription. Proc Natl Acad Sci U S A (2011) 2.08
Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization. J Virol (2010) 1.92
Three-dimensional analysis of budding sites and released virus suggests a revised model for HIV-1 morphogenesis. Cell Host Microbe (2008) 1.91
Structural requirements for recognition of the human immunodeficiency virus type 1 core during host restriction in owl monkey cells. J Virol (2005) 1.79
HLA alleles associated with slow progression to AIDS truly prefer to present HIV-1 p24. PLoS One (2007) 1.77
Structure of the immature retroviral capsid at 8 Å resolution by cryo-electron microscopy. Nature (2012) 1.70
Analysis of the initiating events in HIV-1 particle assembly and genome packaging. PLoS Pathog (2010) 1.66
Domain-swapped dimerization of the HIV-1 capsid C-terminal domain. Proc Natl Acad Sci U S A (2007) 1.66
Interactions between HIV-1 Gag molecules in solution: an inositol phosphate-mediated switch. J Mol Biol (2006) 1.65
CPSF6 defines a conserved capsid interface that modulates HIV-1 replication. PLoS Pathog (2012) 1.64
Modern uses of electron microscopy for detection of viruses. Clin Microbiol Rev (2009) 1.63
Conformation of the HIV-1 Gag protein in solution. J Mol Biol (2006) 1.59
3-O-(3',3'-dimethysuccinyl) betulinic acid inhibits maturation of the human immunodeficiency virus type 1 Gag precursor assembled in vitro. J Virol (2006) 1.58
Association of human immunodeficiency virus type 1 gag with membrane does not require highly basic sequences in the nucleocapsid: use of a novel Gag multimerization assay. J Virol (2005) 1.55
Target cell type-dependent modulation of human immunodeficiency virus type 1 capsid disassembly by cyclophilin A. J Virol (2009) 1.53
The retroviral capsid domain dictates virion size, morphology, and coassembly of gag into virus-like particles. J Virol (2005) 1.52
The host proteins transportin SR2/TNPO3 and cyclophilin A exert opposing effects on HIV-1 uncoating. J Virol (2012) 1.52
Novel approaches to inhibiting HIV-1 replication. Antiviral Res (2009) 1.48
Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution. Nature (2014) 1.46
Disulfide bond stabilization of the hexameric capsomer of human immunodeficiency virus. J Mol Biol (2010) 1.35
Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription. RNA Biol (2010) 1.35
Extreme genetic fragility of the HIV-1 capsid. PLoS Pathog (2013) 1.35
Mutation of dileucine-like motifs in the human immunodeficiency virus type 1 capsid disrupts virus assembly, gag-gag interactions, gag-membrane binding, and virion maturation. J Virol (2006) 1.35
Effect of macromolecular crowding agents on human immunodeficiency virus type 1 capsid protein assembly in vitro. J Virol (2005) 1.32
Nucleocapsid promotes localization of HIV-1 gag to uropods that participate in virological synapses between T cells. PLoS Pathog (2010) 1.31
Cyclophilin A-dependent restriction of human immunodeficiency virus type 1 capsid mutants for infection of nondividing cells. J Virol (2008) 1.30
A strongly transdominant mutation in the human immunodeficiency virus type 1 gag gene defines an Achilles heel in the virus life cycle. J Virol (2009) 1.30
Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid. J Biol Chem (2008) 1.30
A mutation in alpha helix 3 of CA renders human immunodeficiency virus type 1 cyclosporin A resistant and dependent: rescue by a second-site substitution in a distal region of CA. J Virol (2007) 1.28
Human immunodeficiency virus type 1 N-terminal capsid mutants containing cores with abnormally high levels of capsid protein and virtually no reverse transcriptase. J Virol (2003) 1.24
Virus particle core defects caused by mutations in the human immunodeficiency virus capsid N-terminal domain. J Virol (2005) 1.24
Impact of HLA-B*81-associated mutations in HIV-1 Gag on viral replication capacity. J Virol (2012) 1.20
RSV capsid polymorphism correlates with polymerization efficiency and envelope glycoprotein content: implications that nucleation controls morphogenesis. J Mol Biol (2007) 1.19
Nucleic acid binding-induced Gag dimerization in the assembly of Rous sarcoma virus particles in vitro. J Virol (2004) 1.19
Discovery of novel small-molecule HIV-1 replication inhibitors that stabilize capsid complexes. Antimicrob Agents Chemother (2013) 1.18
The conserved carboxy terminus of the capsid domain of human immunodeficiency virus type 1 gag protein is important for virion assembly and release. J Virol (2004) 1.18
Gag induces the coalescence of clustered lipid rafts and tetraspanin-enriched microdomains at HIV-1 assembly sites on the plasma membrane. J Virol (2011) 1.18
Myristoylation is required for human immunodeficiency virus type 1 Gag-Gag multimerization in mammalian cells. J Virol (2007) 1.17
Distinct effects of two HIV-1 capsid assembly inhibitor families that bind the same site within the N-terminal domain of the viral CA protein. J Virol (2012) 1.17
Structure and dynamics of full-length HIV-1 capsid protein in solution. J Am Chem Soc (2013) 1.16
Virus maturation as a new HIV-1 therapeutic target. Expert Opin Ther Targets (2009) 1.13
HIV-1 uncoating: connection to nuclear entry and regulation by host proteins. Virology (2014) 1.12
Irregular and Semi-Regular Polyhedral Models for Rous Sarcoma Virus Cores. Comput Math Methods Med (2008) 1.12
Mutational analysis of the N-terminal domain of Moloney murine leukemia virus capsid protein. J Virol (2007) 1.12
HIV type 1 Gag as a target for antiviral therapy. AIDS Res Hum Retroviruses (2011) 1.08
Unclosed HIV-1 capsids suggest a curled sheet model of assembly. J Mol Biol (2012) 1.08
ATPgammaS disrupts human immunodeficiency virus type 1 virion core integrity. J Virol (2005) 1.08
Protease cleavage leads to formation of mature trimer interface in HIV-1 capsid. PLoS Pathog (2012) 1.07
Second-site suppressors of HIV-1 capsid mutations: restoration of intracellular activities without correction of intrinsic capsid stability defects. Retrovirology (2012) 1.06
Structural and functional insights into the HIV-1 maturation inhibitor binding pocket. PLoS Pathog (2012) 1.06
Analysis of the viral elements required in the nuclear import of HIV-1 DNA. J Virol (2009) 1.05
The host protein Staufen1 interacts with the Pr55Gag zinc fingers and regulates HIV-1 assembly via its N-terminus. Retrovirology (2008) 1.04
STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability. Science (2015) 1.04
Characterization of the in vitro HIV-1 capsid assembly pathway. J Mol Biol (2009) 1.04
Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay. Retrovirology (2013) 1.03
Ty3 capsid mutations reveal early and late functions of the amino-terminal domain. J Virol (2007) 1.03
VSV-G pseudotyping rescues HIV-1 CA mutations that impair core assembly or stability. Retrovirology (2008) 1.03
The host protein Staufen1 participates in human immunodeficiency virus type 1 assembly in live cells by influencing pr55Gag multimerization. J Virol (2007) 1.03
Fundamental differences between the nucleic acid chaperone activities of HIV-1 nucleocapsid protein and Gag or Gag-derived proteins: biological implications. Virology (2010) 1.01
Multiscale computer simulation of the immature HIV-1 virion. Biophys J (2010) 1.00
Mutations in the spacer peptide and adjoining sequences in Rous sarcoma virus Gag lead to tubular budding. J Virol (2008) 1.00
Critical role of conserved hydrophobic residues within the major homology region in mature retroviral capsid assembly. J Virol (2008) 1.00
Complementary Assays Reveal a Low Level of CA Associated with Viral Complexes in the Nuclei of HIV-1-Infected Cells. J Virol (2015) 1.00
Magic angle spinning NMR reveals sequence-dependent structural plasticity, dynamics, and the spacer peptide 1 conformation in HIV-1 capsid protein assemblies. J Am Chem Soc (2013) 0.99
A carboxy-terminally truncated human CPSF6 lacking residues encoded by exon 6 inhibits HIV-1 cDNA synthesis and promotes capsid disassembly. J Virol (2013) 0.99
The interdomain linker region of HIV-1 capsid protein is a critical determinant of proper core assembly and stability. Virology (2011) 0.99
Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain. Retrovirology (2011) 0.99
Distinct roles for nucleic acid in in vitro assembly of purified Mason-Pfizer monkey virus CANC proteins. J Virol (2006) 0.98
Suboptimal inhibition of protease activity in human immunodeficiency virus type 1: effects on virion morphogenesis and RNA maturation. Virology (2008) 0.98
Inhibiting early-stage events in HIV-1 replication by small-molecule targeting of the HIV-1 capsid. J Virol (2012) 0.98
Simulated self-assembly of the HIV-1 capsid: protein shape and native contacts are sufficient for two-dimensional lattice formation. Biophys J (2011) 0.98
Design of in vitro symmetric complexes and analysis by hybrid methods reveal mechanisms of HIV capsid assembly. J Mol Biol (2011) 0.97
Identification of capsid mutations that alter the rate of HIV-1 uncoating in infected cells. J Virol (2014) 0.97
In vivo functions of CPSF6 for HIV-1 as revealed by HIV-1 capsid evolution in HLA-B27-positive subjects. PLoS Pathog (2014) 0.94
HIV-1 Gag associates with specific uropod-directed microdomains in a manner dependent on its MA highly basic region. J Virol (2013) 0.93
The NTD-CTD intersubunit interface plays a critical role in assembly and stabilization of the HIV-1 capsid. Retrovirology (2013) 0.92
Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid. Bioorg Med Chem (2010) 0.92
Roles played by capsid-dependent induction of membrane curvature and Gag-ESCRT interactions in tetherin recruitment to HIV-1 assembly sites. J Virol (2013) 0.92
New approaches for antiviral targeting of HIV assembly. J Mol Biol (2011) 0.92
HLA-Cw*03-restricted CD8+ T-cell responses targeting the HIV-1 gag major homology region drive virus immune escape and fitness constraints compensated for by intracodon variation. J Virol (2010) 0.91
Retroviral capsid assembly: a role for the CA dimer in initiation. J Mol Biol (2009) 0.91
Temporal association of HLA-B*81:01- and HLA-B*39:10-mediated HIV-1 p24 sequence evolution with disease progression. J Virol (2012) 0.91
Characterization of a myristoylated, monomeric HIV Gag protein. Virology (2009) 0.89
High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol (1987) 43.61
Production of high-titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci U S A (1993) 22.33
Isolation and properties of Moloney murine leukemia virus mutants: use of a rapid assay for release of virion reverse transcriptase. J Virol (1981) 13.11
Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene. J Virol (1992) 12.89
Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1989) 12.54
Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release. Proc Natl Acad Sci U S A (1991) 10.05
Form, function, and use of retroviral gag proteins. AIDS (1991) 9.24
Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins. Virology (1987) 7.92
HIV-1 gag proteins: diverse functions in the virus life cycle. Virology (1998) 7.32
Specific incorporation of cyclophilin A into HIV-1 virions. Nature (1994) 7.13
Functional association of cyclophilin A with HIV-1 virions. Nature (1994) 6.82
Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid. Cell (1996) 6.74
Assembly and analysis of conical models for the HIV-1 core. Science (1999) 6.35
Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells. J Virol (1993) 6.11
Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein. Science (1997) 6.10
Image reconstructions of helical assemblies of the HIV-1 CA protein. Nature (2000) 5.60
Structure of the amino-terminal core domain of the HIV-1 capsid protein. Science (1996) 5.44
Self-assembly in vitro of purified CA-NC proteins from Rous sarcoma virus and human immunodeficiency virus type 1. J Virol (1995) 5.21
Formation of a human immunodeficiency virus type 1 core of optimal stability is crucial for viral replication. J Virol (2002) 5.20
Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: implications for membrane association and assembly. Proc Natl Acad Sci U S A (1996) 4.83
Viral late domains. J Virol (2002) 4.51
Proteolytic refolding of the HIV-1 capsid protein amino-terminus facilitates viral core assembly. EMBO J (1998) 4.46
HIV-1 reverse transcription. A termination step at the center of the genome. J Mol Biol (1994) 4.15
A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1. AIDS Res Hum Retroviruses (1994) 3.97
Crystal structure of dimeric HIV-1 capsid protein. Nat Struct Biol (1996) 3.93
Sequential steps in human immunodeficiency virus particle maturation revealed by alterations of individual Gag polyprotein cleavage sites. J Virol (1998) 3.84
The spacer peptide between human immunodeficiency virus capsid and nucleocapsid proteins is essential for ordered assembly and viral infectivity. J Virol (1995) 3.80
Efficient particle production by minimal Gag constructs which retain the carboxy-terminal domain of human immunodeficiency virus type 1 capsid-p2 and a late assembly domain. J Virol (2000) 3.77
A large deletion in the matrix domain of the human immunodeficiency virus gag gene redirects virus particle assembly from the plasma membrane to the endoplasmic reticulum. J Virol (1993) 3.75
Cryo-electron microscopy reveals ordered domains in the immature HIV-1 particle. Curr Biol (1997) 3.59
Molecular recognition in the HIV-1 capsid/cyclophilin A complex. J Mol Biol (1997) 3.50
Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis. J Virol (1994) 3.48
Functional domains of the capsid protein of human immunodeficiency virus type 1. J Virol (1994) 3.47
Assembly of recombinant human immunodeficiency virus type 1 capsid protein in vitro. J Virol (1992) 3.44
In vitro assembly properties of purified bacterially expressed capsid proteins of human immunodeficiency virus. Eur J Biochem (1997) 3.38
Efficient HIV-1 replication can occur in the absence of the viral matrix protein. EMBO J (1998) 3.30
Supramolecular organization of immature and mature murine leukemia virus revealed by electron cryo-microscopy: implications for retroviral assembly mechanisms. Proc Natl Acad Sci U S A (1998) 3.24
Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations. Virology (1997) 3.24
Differential membrane binding of the human immunodeficiency virus type 1 matrix protein. J Virol (1996) 3.19
Binding of human immunodeficiency virus type 1 Gag to membrane: role of the matrix amino terminus. J Virol (1999) 3.13
Membrane binding of human immunodeficiency virus type 1 matrix protein in vivo supports a conformational myristyl switch mechanism. J Virol (1997) 3.07
A putative alpha-helical structure which overlaps the capsid-p2 boundary in the human immunodeficiency virus type 1 Gag precursor is crucial for viral particle assembly. J Virol (1998) 3.06
Biochemical and structural analysis of isolated mature cores of human immunodeficiency virus type 1. J Virol (2000) 2.80
Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution. Acta Crystallogr D Biol Crystallogr (1999) 2.77
Genetic analysis of the major homology region of the Rous sarcoma virus Gag protein. J Virol (1995) 2.76
Analysis of the assembly function of the human immunodeficiency virus type 1 gag protein nucleocapsid domain. J Virol (1998) 2.71
Association of Nef with the human immunodeficiency virus type 1 core. J Virol (1999) 2.62
Crystal structure of SIV matrix antigen and implications for virus assembly. Nature (1995) 2.59
Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity. J Virol (1995) 2.56
Mutational analysis of the major homology region of Mason-Pfizer monkey virus by use of saturation mutagenesis. J Virol (1992) 2.56
N-Terminal extension of human immunodeficiency virus capsid protein converts the in vitro assembly phenotype from tubular to spherical particles. J Virol (1998) 2.49
Basic residues in human immunodeficiency virus type 1 nucleocapsid promote virion assembly via interaction with RNA. J Virol (2000) 2.46
Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin A. J Virol (1996) 2.39
Organization of immature human immunodeficiency virus type 1. J Virol (2001) 2.34
Head-to-tail dimers and interdomain flexibility revealed by the crystal structure of HIV-1 capsid protein (p24) complexed with a monoclonal antibody Fab. EMBO J (1999) 2.33
Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometry. J Mol Biol (2003) 2.32
Opposing effects of human immunodeficiency virus type 1 matrix mutations support a myristyl switch model of gag membrane targeting. J Virol (1999) 2.31
The role of Gag in human immunodeficiency virus type 1 virion morphogenesis and early steps of the viral life cycle. J Virol (1996) 2.31
Cell membrane vesicles are a major contaminant of gradient-enriched human immunodeficiency virus type-1 preparations. Virology (1997) 2.30
Human immunodeficiency virus type 1 N-terminal capsid mutants that exhibit aberrant core morphology and are blocked in initiation of reverse transcription in infected cells. J Virol (2001) 2.17
Relationship between human immunodeficiency virus type 1 Gag multimerization and membrane binding. J Virol (2000) 2.07
Structural biology of HIV. J Mol Biol (1999) 2.03
Characterization of a putative alpha-helix across the capsid-SP1 boundary that is critical for the multimerization of human immunodeficiency virus type 1 gag. J Virol (2002) 1.96
Model for lentivirus capsid core assembly based on crystal dimers of EIAV p26. J Mol Biol (1999) 1.93
Solution structure and dynamics of the Rous sarcoma virus capsid protein and comparison with capsid proteins of other retroviruses. J Mol Biol (2000) 1.91
The C-terminal half of the human immunodeficiency virus type 1 Gag precursor is sufficient for efficient particle assembly. J Virol (1998) 1.91
The HIV-1 assembly machine. AIDS (2001) 1.88
Characterization of Rous sarcoma virus Gag particles assembled in vitro. J Virol (2001) 1.85
The role of nucleocapsid of HIV-1 in virus assembly. Virology (1998) 1.84
Structure and self-association of the Rous sarcoma virus capsid protein. Structure (2000) 1.83
Proline residues in the HIV-1 NH2-terminal capsid domain: structure determinants for proper core assembly and subsequent steps of early replication. Virology (2000) 1.77
Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry (1991) 1.76
Solution structure of the capsid protein from the human T-cell leukemia virus type-I. J Mol Biol (1999) 1.75
Characterization of deletion mutations in the capsid region of human immunodeficiency virus type 1 that affect particle formation and Gag-Pol precursor incorporation. J Virol (1995) 1.73
Nucleic acid-independent retrovirus assembly can be driven by dimerization. J Virol (2002) 1.66
Tsg101: HIV-1's ticket to ride. Trends Microbiol (2002) 1.58
Second-site suppressors of Rous sarcoma virus Ca mutations: evidence for interdomain interactions. J Virol (2001) 1.55
Structural analysis of human immunodeficiency virus type 1 Gag protein interactions, using cysteine-specific reagents. J Virol (1996) 1.55
The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix. J Virol (1997) 1.52
Contribution of surface salt bridges to protein stability. Biochemistry (2000) 1.48
Amino acid substitutions in the CA protein of Moloney murine leukemia virus that block early events in infection. Virology (1996) 1.47
Identification of three major phosphorylation sites within HIV-1 capsid. Role of phosphorylation during the early steps of infection. J Biol Chem (1999) 1.45
Retrovirus capsid protein assembly arrangements. J Mol Biol (2003) 1.40
Resistance is futile: assimilation of cellular machinery by HIV-1. Immunity (2001) 1.40
Viral DNA synthesis defects in assembly-competent Rous sarcoma virus CA mutants. J Virol (2001) 1.39
Immunologic and proteolytic analysis of HIV-1 reverse transcriptase structure. Virology (1990) 1.38
Structural analysis of the N-terminal domain of the human T-cell leukemia virus capsid protein. J Mol Biol (2001) 1.38
Mutations in the N-terminal domain of human immunodeficiency virus type 1 nucleocapsid protein affect virion core structure and proviral DNA synthesis. J Virol (1997) 1.31
Mutations in the Ty3 major homology region affect multiple steps in Ty3 retrotransposition. J Virol (1996) 1.30
Characterization of HIV-1 p24 self-association using analytical affinity chromatography. Proteins (1992) 1.20
Molecular events in the assembly of retrovirus particles. Adv Exp Med Biol (1998) 1.16
Cyclophilin A incorporation is not required for human immunodeficiency virus type 1 particle maturation and does not destabilize the mature capsid. Virology (1999) 1.13
Rescue of multiple viral functions by a second-site suppressor of a human immunodeficiency virus type 1 nucleocapsid mutation. J Virol (2000) 1.06
Molecular organization of Mason-Pfizer monkey virus capsids assembled from Gag polyprotein in Escherichia coli. J Virol (2002) 1.02
Identification of a minimal HIV-1 gag domain sufficient for self-association. Virology (2002) 1.01
Cryoelectron microscopic examination of human immunodeficiency virus type 1 virions with mutations in the cyclophilin A binding loop. J Virol (1998) 0.90
Ultrastructure and morphogenesis of human immunodeficiency virus. J Electron Microsc (Tokyo) (1996) 0.87
HIV-1 and Ebola virus: the getaway driver nabbed. Nat Med (2001) 0.86
The protein network of HIV budding. Cell (2003) 7.82
Retrovirus budding. Annu Rev Cell Dev Biol (2004) 7.16
Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor. Proc Natl Acad Sci U S A (2006) 6.82
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis. EMBO J (2007) 5.31
Formation of a human immunodeficiency virus type 1 core of optimal stability is crucial for viral replication. J Virol (2002) 5.20
An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein. Cell Host Microbe (2007) 4.17
X-ray structures of the hexameric building block of the HIV capsid. Cell (2009) 4.08
The structural biology of HIV assembly. Curr Opin Struct Biol (2008) 3.71
Global landscape of HIV-human protein complexes. Nature (2011) 3.70
ESCRT-III recognition by VPS4 ATPases. Nature (2007) 3.64
Mechanisms of enveloped RNA virus budding. Trends Cell Biol (2002) 3.36
Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells. EMBO J (2007) 3.17
Assembly properties of the human immunodeficiency virus type 1 CA protein. J Virol (2004) 3.09
Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding. Cell (2007) 3.06
The molecular mechanism of hepcidin-mediated ferroportin down-regulation. Mol Biol Cell (2007) 2.99
Ubiquitin interactions of NZF zinc fingers. EMBO J (2004) 2.72
Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein. Nat Struct Biol (2002) 2.66
ESCRT-III protein requirements for HIV-1 budding. Cell Host Microbe (2011) 2.61
Structural and mechanistic studies of VPS4 proteins. EMBO J (2005) 2.58
Structure and functional interactions of the Tsg101 UEV domain. EMBO J (2002) 2.40
Hexagonal assembly of a restricting TRIM5alpha protein. Proc Natl Acad Sci U S A (2010) 2.40
HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein. J Cell Biol (2003) 2.38
Species-specific tropism determinants in the human immunodeficiency virus type 1 capsid. J Virol (2004) 2.37
Biochemical characterization of a recombinant TRIM5alpha protein that restricts human immunodeficiency virus type 1 replication. J Virol (2008) 2.30
Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding. Dev Cell (2008) 2.23
Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin A. Proc Natl Acad Sci U S A (2002) 2.19
Structure and ubiquitin binding of the ubiquitin-interacting motif. J Biol Chem (2003) 2.19
Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding. Cell Host Microbe (2007) 2.18
Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A. Proc Natl Acad Sci U S A (2005) 2.12
Three-dimensional structure of HIV-1 virus-like particles by electron cryotomography. J Mol Biol (2004) 2.10
Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release. J Virol (2006) 2.06
Structural basis for ESCRT-III protein autoinhibition. Nat Struct Mol Biol (2009) 1.98
The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding. J Biol Chem (2004) 1.92
ALIX-CHMP4 interactions in the human ESCRT pathway. Proc Natl Acad Sci U S A (2008) 1.91
Membrane fission reactions of the mammalian ESCRT pathway. Annu Rev Biochem (2013) 1.91
Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance. Proc Natl Acad Sci U S A (2010) 1.89
Evidence for a new viral late-domain core sequence, FPIV, necessary for budding of a paramyxovirus. J Virol (2005) 1.88
Structure of the antiviral assembly inhibitor CAP-1 complex with the HIV-1 CA protein. J Mol Biol (2007) 1.78
Structural insights into the catalytic mechanism of cyclophilin A. Nat Struct Biol (2003) 1.78
Structural and functional studies of ALIX interactions with YPX(n)L late domains of HIV-1 and EIAV. Nat Struct Mol Biol (2007) 1.76
The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells. J Biol Chem (2005) 1.73
Structure and ubiquitin interactions of the conserved zinc finger domain of Npl4. J Biol Chem (2003) 1.72
Virus budding and the ESCRT pathway. Cell Host Microbe (2013) 1.70
NEDD4L overexpression rescues the release and infectivity of human immunodeficiency virus type 1 constructs lacking PTAP and YPXL late domains. J Virol (2008) 1.60
Three-dimensional structure of the M-MuLV CA protein on a lipid monolayer: a general model for retroviral capsid assembly. EMBO J (2003) 1.58
Biochemical analyses of human IST1 and its function in cytokinesis. Mol Biol Cell (2009) 1.57
Implications for viral capsid assembly from crystal structures of HIV-1 Gag(1-278) and CA(N)(133-278). Biochemistry (2006) 1.41
Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat Struct Mol Biol (2006) 1.41
Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p. J Mol Biol (2008) 1.33
Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells. PLoS One (2013) 1.29
Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations. Proc Natl Acad Sci U S A (2010) 1.29
Chk1 inhibition and Wee1 inhibition combine synergistically to impede cellular proliferation. Cancer Biol Ther (2011) 1.28
The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer. Proc Natl Acad Sci U S A (2014) 1.27
Discovery of novel small-molecule HIV-1 replication inhibitors that stabilize capsid complexes. Antimicrob Agents Chemother (2013) 1.18
Distinct effects of two HIV-1 capsid assembly inhibitor families that bind the same site within the N-terminal domain of the viral CA protein. J Virol (2012) 1.17
The Polycomb-associated protein Rybp is a ubiquitin binding protein. FEBS Lett (2006) 1.16
Biochemical and structural studies of yeast Vps4 oligomerization. J Mol Biol (2008) 1.15
Good to CU. Nature (2003) 1.13
Identification and structural characterization of the ALIX-binding late domains of simian immunodeficiency virus SIVmac239 and SIVagmTan-1. J Virol (2010) 1.06
ALIX is a Lys63-specific polyubiquitin binding protein that functions in retrovirus budding. Dev Cell (2012) 1.01
Suppression of HIV-1 protease inhibitor resistance by phosphonate-mediated solvent anchoring. J Mol Biol (2006) 1.00
Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transport. J Biol Chem (2012) 0.99
Activation of the retroviral budding factor ALIX. J Virol (2011) 0.97
Molecular characterization of the Ran-binding zinc finger domain of Nup153. J Biol Chem (2007) 0.94
ESCRT-III CHMP2A and CHMP3 form variable helical polymers in vitro and act synergistically during HIV-1 budding. Cell Microbiol (2012) 0.92
Triterpene based compounds with potent anti-maturation activity against HIV-1. Bioorg Med Chem Lett (2008) 0.84
Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines. J Med Chem (2011) 0.84
Structure of the Bro1 domain protein BROX and functional analyses of the ALIX Bro1 domain in HIV-1 budding. PLoS One (2011) 0.83
How HIV finds the door. Proc Natl Acad Sci U S A (2012) 0.82
Two new structures of Ub-receptor complexes. U2. Nat Struct Mol Biol (2006) 0.81
Attenuated protein expression vectors for use in siRNA rescue experiments. Biotechniques (2012) 0.81
ESCRT requirements for EIAV budding. Retrovirology (2013) 0.80
Structural biology: ESCRT service. Nature (2007) 0.78
Building a super elongation complex for HIV. Elife (2013) 0.75
Macromolecular assemblages. Curr Opin Struct Biol (2011) 0.75
Macromolecular assemblies. Curr Opin Struct Biol (2013) 0.75
Assemble, replicate, remodel and evade. Curr Opin Virol (2012) 0.75