Published in Science on January 13, 2005
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Antibiotic resistance is ancient. Nature (2011) 4.83
The biochemical architecture of an ancient adaptive landscape. Science (2005) 3.39
A draft genome of Yersinia pestis from victims of the Black Death. Nature (2011) 3.18
Local migration promotes competitive restraint in a host-pathogen 'tragedy of the commons'. Nature (2006) 2.58
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Evolving protein functional diversity in new genes of Drosophila. Proc Natl Acad Sci U S A (2004) 1.55
Direct demonstration of an adaptive constraint. Science (2006) 1.51
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Simple sequences are rare in the Protein Data Bank. Proteins (2002) 1.34
Gene gain and gene loss in streptococcus: is it driven by habitat? Mol Biol Evol (2006) 1.31
Enzyme kinetics, substitutable resources and competition: from biochemistry to frequency-dependent selection in lac. Genetics (2002) 1.30
Are similarity- or phylogeny-based methods more appropriate for classifying internal transcribed spacer (ITS) metagenomic amplicons? New Phytol (2011) 1.23
The role of laterally transferred genes in adaptive evolution. BMC Evol Biol (2007) 1.18
The pattern of amino acid replacements in alpha/beta-barrels. Mol Biol Evol (2002) 1.16
Second-pandemic strain of Vibrio cholerae from the Philadelphia cholera outbreak of 1849. N Engl J Med (2014) 1.16
A non-long terminal repeat retrotransposon family is restricted to the germ line micronucleus of the ciliated protozoan Tetrahymena thermophila. Eukaryot Cell (2004) 1.12
Assigning sequences to species in the absence of large interspecific differences. Mol Phylogenet Evol (2010) 1.12
An integrated approach to functional genomics: construction of a novel reporter gene fusion library for Sinorhizobium meliloti. Appl Environ Microbiol (2006) 1.10
Fitness consequences of a regulatory polymorphism in a seasonal environment. Proc Natl Acad Sci U S A (2003) 1.05
Evolution of specialists in an experimental microcosm. Genetics (2004) 1.05
Genome-wide evidence for selection acting on single amino acid repeats. Genome Res (2010) 1.00
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Unrestricted migration favours virulent pathogens in experimental metapopulations: evolutionary genetics of a rapacious life history. Philos Trans R Soc Lond B Biol Sci (2010) 0.98
Uncovering rate variation of lateral gene transfer during bacterial genome evolution. BMC Genomics (2008) 0.96
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A phylogenetic analysis of the pSymB replicon from the Sinorhizobium meliloti genome reveals a complex evolutionary history. Can J Microbiol (2003) 0.93
Dinucleotide compositional analysis of Sinorhizobium meliloti using the genome signature: distinguishing chromosomes and plasmids. Funct Integr Genomics (2002) 0.92
Gene amelioration demonstrated: the journey of nascent genes in bacteria. Genome (2008) 0.92
Selection and slippage creating serine homopolymers. Mol Biol Evol (2006) 0.91
Lateral gene transfer in Mycobacterium avium subspecies paratuberculosis. Can J Microbiol (2006) 0.89
Rapid identification and mapping of insertion sequences in Escherichia coli genomes using vectorette PCR. BMC Microbiol (2004) 0.88
The LysR-type PcaQ protein regulates expression of a protocatechuate-inducible ABC-type transport system in Sinorhizobium meliloti. Microbiology (2011) 0.87
Does gene translocation accelerate the evolution of laterally transferred genes? Genetics (2009) 0.86
Asymmetrical evolution of cytochrome bd subunits. J Mol Evol (2006) 0.86
Transcription, translation, and the evolution of specialists and generalists. Mol Biol Evol (2009) 0.84
Identification of conflicting selective effects on highly expressed genes. Evol Bioinform Online (2007) 0.84
The evolution of the class A scavenger receptors. BMC Evol Biol (2012) 0.83
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An empirical test of the concomitantly variable codon hypothesis. Proc Natl Acad Sci U S A (2007) 0.82
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"Patchy-tachy" leads to false positives for recombination. Mol Biol Evol (2011) 0.82
Increased polymorphism near low-complexity sequences across the genomes of Plasmodium falciparum isolates. Genome Biol Evol (2011) 0.82
Evolution of enzymatic activities of testis-specific short-chain dehydrogenase/reductase in Drosophila. J Mol Evol (2010) 0.81
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The argRB of Escherichia coli is rare in isolates obtained from natural sources. Gene (2006) 0.80
Description of a riboflavin biosynthetic gene variant prevalent in the phylum Proteobacteria. J Bacteriol (2013) 0.80
Inferring bacterial genome flux while considering truncated genes. Genetics (2010) 0.80
Transcriptomic and metabolomic analysis of Yukon Thellungiella plants grown in cabinets and their natural habitat show phenotypic plasticity. BMC Plant Biol (2012) 0.79
Inferring sequence regions under functional divergence in duplicate genes. Bioinformatics (2011) 0.78
Nucleotide substitution bias within the genus Drosophila affects the pattern of proteome evolution. Genome Biol Evol (2009) 0.78
Enzymatic characterization of a monomeric isocitrate dehydrogenase from Streptomyces lividans TK54. Biochimie (2009) 0.78
Simple sequence in brain and nervous system specific proteins. Genome (2005) 0.77
The effect of sampling from subdivided populations on species identification with DNA barcodes using a Bayesian statistical approach. Mol Phylogenet Evol (2012) 0.76
Increased substitution rates surrounding low-complexity regions within primate proteins. Genome Biol Evol (2014) 0.76
Amplicon pyrosequencing late Pleistocene permafrost: the removal of putative contaminant sequences and small-scale reproducibility. Mol Ecol Resour (2013) 0.76
Evolution of a transition state: role of Lys100 in the active site of isocitrate dehydrogenase. Chembiochem (2014) 0.75
Efficient algorithms for counting and reporting segregating sites in genomic sequences. J Comput Biol (2007) 0.75
Selection in a cyclical environment: possible impact of phenotypic lag on Darwinian fitness. J Mol Evol (2005) 0.75