Published in J Cell Sci on January 18, 2005
Flagellar membrane localization via association with lipid rafts. J Cell Sci (2009) 1.49
Secretion without Golgi. J Cell Biochem (2008) 1.39
Unconventional secretion of AcbA in Dictyostelium discoideum through a vesicular intermediate. Eukaryot Cell (2010) 1.03
Cell surface counter receptors are essential components of the unconventional export machinery of galectin-1. J Cell Biol (2005) 1.02
Acylation-dependent export of Trypanosoma cruzi phosphoinositide-specific phospholipase C to the outer surface of amastigotes. J Biol Chem (2010) 0.98
Molecular determinants of ciliary membrane localization of Trypanosoma cruzi flagellar calcium-binding protein. J Biol Chem (2011) 0.93
The glycosylphosphatidylinositol-PLC in Trypanosoma brucei forms a linear array on the exterior of the flagellar membrane before and after activation. PLoS Pathog (2009) 0.89
Acylation in trypanosomatids: an essential process and potential drug target. Trends Parasitol (2014) 0.88
Trafficking and release of Leishmania metacyclic HASPB on macrophage invasion. Cell Microbiol (2012) 0.88
A direct role for ATP1A1 in unconventional secretion of fibroblast growth factor 2. J Biol Chem (2014) 0.86
Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases. Genome Res (2011) 0.86
In vivo recognition of ovalbumin expressed by transgenic Leishmania is determined by its subcellular localization. J Immunol (2006) 0.85
Secretory pathway of cellulase: a mini-review. Biotechnol Biofuels (2013) 0.82
P2X7 receptor activation regulates rapid unconventional export of transglutaminase-2. J Cell Sci (2015) 0.80
Ecotin-like serine peptidase inhibitor ISP1 of Leishmania major plays a role in flagellar pocket dynamics and promastigote differentiation. Cell Microbiol (2012) 0.78
Hydrophilic Acylated Surface Protein A (HASPA) of Leishmania donovani: Expression, Purification and Biophysico-Chemical Characterization. Protein J (2017) 0.75
The genome of the kinetoplastid parasite, Leishmania major. Science (2005) 8.64
Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science (2009) 4.58
Comparative genomic analysis of three Leishmania species that cause diverse human disease. Nat Genet (2007) 4.58
TriTrypDB: a functional genomic resource for the Trypanosomatidae. Nucleic Acids Res (2009) 3.79
The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell (2008) 3.51
Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. EMBO J (2002) 3.03
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness. Nature (2010) 2.90
Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg (2004) 2.46
Distinct targeting pathways for the membrane insertion of tail-anchored (TA) proteins. J Cell Sci (2008) 2.11
Myristoyl-CoA:protein N-myristoyltransferase, an essential enzyme and potential drug target in kinetoplastid parasites. J Biol Chem (2002) 2.08
Hide and run. Arginine-based endoplasmic-reticulum-sorting motifs in the assembly of heteromultimeric membrane proteins. EMBO Rep (2005) 2.04
Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Genome Res (2011) 1.90
GeneDB--an annotation database for pathogens. Nucleic Acids Res (2011) 1.82
14-3-3 dimers probe the assembly status of multimeric membrane proteins. Curr Biol (2003) 1.79
Molecules incorporating a benzothiazole core scaffold inhibit the N-myristoyltransferase of Plasmodium falciparum. Biochem J (2007) 1.75
Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses. Nat Med (2003) 1.75
Bat3 promotes the membrane integration of tail-anchored proteins. J Cell Sci (2010) 1.71
Toll-like receptor 4 contributes to efficient control of infection with the protozoan parasite Leishmania major. Infect Immun (2004) 1.65
Biogenesis of tail-anchored proteins: the beginning for the end? J Cell Sci (2009) 1.64
Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics. Mol Biochem Parasitol (2003) 1.61
Regulated secretion of macrophage migration inhibitory factor is mediated by a non-classical pathway involving an ABC transporter. FEBS Lett (2003) 1.59
Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major. J Biol Chem (2003) 1.52
Sphingolipid-free Leishmania are defective in membrane trafficking, differentiation and infectivity. Mol Microbiol (2004) 1.45
The protozoan inositol phosphorylceramide synthase: a novel drug target that defines a new class of sphingolipid synthase. J Biol Chem (2006) 1.39
Recombinase-mediated cassette exchange (RMCE): traditional concepts and current challenges. J Mol Biol (2011) 1.38
Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs. PLoS Negl Trop Dis (2012) 1.36
SEC18/NSF-independent, protein-sorting pathway from the yeast cortical ER to the plasma membrane. J Cell Biol (2005) 1.33
N-myristoyltransferase: a prospective drug target for protozoan parasites. ChemMedChem (2008) 1.33
A direct role for phosphatidylinositol-4,5-bisphosphate in unconventional secretion of fibroblast growth factor 2. Traffic (2008) 1.33
Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells. PLoS Pathog (2010) 1.32
A comprehensive transcript map of the mouse Gnas imprinted complex. Genome Res (2003) 1.32
Diversity in unconventional protein secretion. J Cell Sci (2012) 1.31
Functional analysis of TbARL1, an N-myristoylated Golgi protein essential for viability in bloodstream trypanosomes. J Cell Sci (2005) 1.30
Characterization and selective inhibition of myristoyl-CoA:protein N-myristoyltransferase from Trypanosoma brucei and Leishmania major. Biochem J (2006) 1.30
The cancer antigen CA125 represents a novel counter receptor for galectin-1. J Cell Sci (2003) 1.28
N-myristoyltransferase from Leishmania donovani: structural and functional characterisation of a potential drug target for visceral leishmaniasis. J Mol Biol (2009) 1.28
Myristoyl-CoA:protein N-myristoyltransferase depletion in trypanosomes causes avirulence and endocytic defects. Mol Biochem Parasitol (2009) 1.28
Trypanosoma brucei ARF1 plays a central role in endocytosis and golgi-lysosome trafficking. Mol Biol Cell (2006) 1.26
Loss of ceramide synthase 3 causes lethal skin barrier disruption. Hum Mol Genet (2011) 1.26
Site-specific N-terminal labelling of proteins in vitro and in vivo using N-myristoyl transferase and bioorthogonal ligation chemistry. Chem Commun (Camb) (2007) 1.25
The Golgi-associated protein p115 mediates the secretion of macrophage migration inhibitory factor. J Immunol (2009) 1.25
14-3-3 proteins in membrane protein transport. Biol Chem (2006) 1.25
Kinetoplastid PPEF phosphatases: dual acylated proteins expressed in the endomembrane system of Leishmania. Mol Biochem Parasitol (2006) 1.21
Mechanistic basis of infertility of mouse intersubspecific hybrids. Proc Natl Acad Sci U S A (2013) 1.20
Functional reconstitution of COPI coat assembly and disassembly using chemically defined components. Proc Natl Acad Sci U S A (2003) 1.20
The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol. J Biol Chem (2005) 1.19
Biosynthetic FGF-2 is targeted to non-lipid raft microdomains following translocation to the extracellular surface of CHO cells. J Cell Sci (2002) 1.19
Intracellular traffic of the K+ channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins. J Physiol (2009) 1.18
Regulatory variation at glypican-3 underlies a major growth QTL in mice. PLoS Biol (2005) 1.18
Unconventional secretion of fibroblast growth factor 2 is mediated by direct translocation across the plasma membrane of mammalian cells. J Biol Chem (2003) 1.17
A conserved, lipid-mediated sorting mechanism of yeast Ist2 and mammalian STIM proteins to the peripheral ER. Traffic (2009) 1.16
The retention factor p11 confers an endoplasmic reticulum-localization signal to the potassium channel TASK-1. Traffic (2006) 1.15
Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds. PLoS Negl Trop Dis (2009) 1.14
A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy. PLoS Genet (2010) 1.13
Cell-surface heparan sulfate proteoglycans are essential components of the unconventional export machinery of FGF-2. Proc Natl Acad Sci U S A (2006) 1.13
The stage-regulated HASPB and SHERP proteins are essential for differentiation of the protozoan parasite Leishmania major in its sand fly vector, Phlebotomus papatasi. Cell Microbiol (2010) 1.13
Organization and evolution of a gene-rich region of the mouse genome: a 12.7-Mb region deleted in the Del(13)Svea36H mouse. Genome Res (2004) 1.12
IkappaB genetic polymorphisms and invasive pneumococcal disease. Am J Respir Crit Care Med (2007) 1.11
Differentially expressed protein markers in human submandibular and sublingual secretions. Int J Oncol (2004) 1.11
Recombinase-mediated cassette exchange (RMCE) - a rapidly-expanding toolbox for targeted genomic modifications. Gene (2012) 1.11
Prospective isolation of late development multipotent precursors whose migration is promoted by EGFR. Dev Biol (2005) 1.10
Structures of Get3, Get4, and Get5 provide new models for TA membrane protein targeting. Structure (2010) 1.10
Scavenging of 14-3-3 proteins reveals their involvement in the cell-surface transport of ATP-sensitive K+ channels. J Cell Sci (2006) 1.08
Unconventional protein secretion: membrane translocation of FGF-2 does not require protein unfolding. J Cell Sci (2004) 1.08
Detection of picomolar levels of interleukin-8 in human saliva by SPR. Lab Chip (2005) 1.08
Unconventional secretion of fibroblast growth factor 2 and galectin-1 does not require shedding of plasma membrane-derived vesicles. FEBS Lett (2008) 1.07
SH4-domain-induced plasma membrane dynamization promotes bleb-associated cell motility. J Cell Sci (2007) 1.07
Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen. Proc Natl Acad Sci U S A (2005) 1.07
RepSeq--a database of amino acid repeats present in lower eukaryotic pathogens. BMC Bioinformatics (2007) 1.06
Optimized signal peptides for the development of high expressing CHO cell lines. Biotechnol Bioeng (2013) 1.04
Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse. Genomics (2002) 1.03
Cell surface counter receptors are essential components of the unconventional export machinery of galectin-1. J Cell Biol (2005) 1.02
T regulatory cells control susceptibility to invasive pneumococcal pneumonia in mice. PLoS Pathog (2012) 1.01
Membrane proteins as 14-3-3 clients in functional regulation and intracellular transport. Physiology (Bethesda) (2011) 1.00
Novel cargo-binding site in the beta and delta subunits of coatomer. J Cell Biol (2007) 1.00
The nucleobase-ascorbate transporter (NAT) signature motif in UapA defines the function of the purine translocation pathway. J Mol Biol (2005) 1.00
Chromosome segregation by the Escherichia coli Min system. Mol Syst Biol (2013) 0.99
The yeast CLC protein counteracts vesicular acidification during iron starvation. J Cell Sci (2010) 0.99
Adoptive immunotherapy against experimental visceral leishmaniasis with CD8+ T cells requires the presence of cognate antigen. Infect Immun (2006) 0.98
Therapeutic vaccination with recombinant adenovirus reduces splenic parasite burden in experimental visceral leishmaniasis. J Infect Dis (2012) 0.98
An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei. Mol Cell Biol (2005) 0.97
Rafts and sphingolipid biosynthesis in the kinetoplastid parasitic protozoa. Mol Microbiol (2004) 0.97
A novel flow cytometric assay to quantify interactions between proteins and membrane lipids. J Lipid Res (2009) 0.96
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion. J Biol Chem (2012) 0.96
Structure-based design of potent and selective Leishmania N-myristoyltransferase inhibitors. J Med Chem (2014) 0.95
Get3 is a holdase chaperone and moves to deposition sites for aggregated proteins when membrane targeting is blocked. J Cell Sci (2012) 0.95
Chemokine gene expression in toll-like receptor-competent and -deficient mice infected with Leishmania major. Infect Immun (2004) 0.95
Expression profiling of the Leishmania life cycle: cDNA arrays identify developmentally regulated genes present but not annotated in the genome. Mol Biochem Parasitol (2004) 0.94