Published in J Neurosci on January 19, 2005
Epigenetic memory loss in aging oligodendrocytes in the corpus callosum. Neurobiol Aging (2006) 1.21
Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system. Dis Model Mech (2008) 1.14
Naturally presented peptides on major histocompatibility complex I and II molecules eluted from central nervous system of multiple sclerosis patients. Mol Cell Proteomics (2009) 1.01
Post-translational modifications of nucleosomal histones in oligodendrocyte lineage cells in development and disease. J Mol Neurosci (2008) 0.96
Evaluating epigenetic landmarks in the brain of multiple sclerosis patients: a contribution to the current debate on disease pathogenesis. Prog Neurobiol (2008) 0.91
The cancer drug tamoxifen: a potential therapeutic treatment for spinal cord injury. J Neurotrauma (2013) 0.89
Increased stathmin1 expression in the dentate gyrus of mice causes abnormal axonal arborizations. PLoS One (2010) 0.86
Re-expression of a developmentally restricted potassium channel in autoimmune demyelination: Kv1.4 is implicated in oligodendroglial proliferation. Am J Pathol (2007) 0.81
Characterization of human septic sera induced gene expression modulation in human myocytes. Int J Clin Exp Med (2009) 0.78
Hypothermia reduces toll-like receptor 3-activated microglial interferon-β and nitric oxide production. Mediators Inflamm (2013) 0.76
An integrated approach to design novel therapeutic interventions for demyelinating disorders. Eur J Neurosci (2012) 0.75
A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica. Brain (2002) 6.85
The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat Immunol (2007) 5.83
Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain (2005) 5.29
Intrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica. Ann Neurol (2009) 4.88
Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis. Brain (2007) 4.50
Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat Neurosci (2008) 3.24
Epstein-Barr virus infection is not a characteristic feature of multiple sclerosis brain. Brain (2009) 3.04
Remyelination is extensive in a subset of multiple sclerosis patients. Brain (2006) 2.43
The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron (2007) 2.38
Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol (2005) 2.34
Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium. Brain Pathol (2008) 1.85
Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis. Proc Natl Acad Sci U S A (2006) 1.79
Cathepsin D deficiency is associated with a human neurodegenerative disorder. Am J Hum Genet (2006) 1.76
The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis. Neurochem Res (2006) 1.71
Mechanisms of acute axonal degeneration in the optic nerve in vivo. Proc Natl Acad Sci U S A (2010) 1.70
The Yin and Yang of YY1 in the nervous system. J Neurochem (2008) 1.68
Early MRI changes in a mouse model of multiple sclerosis are predictive of severe inflammatory tissue damage. Brain (2007) 1.63
Thermal hypoaesthesia differentiates secondary restless legs syndrome associated with small fibre neuropathy from primary restless legs syndrome. Brain (2010) 1.62
Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J Neurosci (2007) 1.58
Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases. J Neuropathol Exp Neurol (2003) 1.55
Remyelinated lesions in multiple sclerosis: magnetic resonance image appearance. Arch Neurol (2003) 1.55
Effects of interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions. Exp Neurol (2006) 1.55
Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS. Mech Dev (2005) 1.53
Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination. Acta Neuropathol (2012) 1.53
A molecular insight of Hes5-dependent inhibition of myelin gene expression: old partners and new players. EMBO J (2006) 1.49
Widespread demyelination in the cerebellar cortex in multiple sclerosis. Brain Pathol (2007) 1.49
Lack of the cell-cycle inhibitor p27Kip1 results in selective increase of transit-amplifying cells for adult neurogenesis. J Neurosci (2002) 1.48
Combinatorial profiles of oligodendrocyte-selective classes of transcriptional regulators differentially modulate myelin basic protein gene expression. J Neurosci (2005) 1.47
Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs. J Clin Invest (2008) 1.44
Remyelination in multiple sclerosis. J Neurol Sci (2003) 1.43
Extensive cortical remyelination in patients with chronic multiple sclerosis. Brain Pathol (2007) 1.41
Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. J Neurosci (2006) 1.41
Synergistic interactions of lipids and myelin basic protein. Proc Natl Acad Sci U S A (2004) 1.38
A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination. Brain (2006) 1.35
Targeting experimental autoimmune encephalomyelitis lesions to a predetermined axonal tract system allows for refined behavioral testing in an animal model of multiple sclerosis. Am J Pathol (2004) 1.31
Enhancing remyelination in disease--can we wrap it up? Brain (2011) 1.25
Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation. EMBO J (2003) 1.25
Remodeling of axonal connections contributes to recovery in an animal model of multiple sclerosis. J Exp Med (2004) 1.25
The glial or neuronal fate choice of oligodendrocyte progenitors is modulated by their ability to acquire an epigenetic memory. J Neurosci (2007) 1.22
The pathology of multiple sclerosis. Neurol Clin (2005) 1.22
Epigenetic memory loss in aging oligodendrocytes in the corpus callosum. Neurobiol Aging (2006) 1.21
Multiple roles of Id4 in developmental myelination: predicted outcomes and unexpected findings. Glia (2006) 1.21
Multicontrast MRI of remyelination in the central nervous system. NMR Biomed (2005) 1.19
Myelin localization of peptidylarginine deiminases 2 and 4: comparison of PAD2 and PAD4 activities. Lab Invest (2008) 1.15
Neurotrophic cross-talk between the nervous and immune systems: implications for neurological diseases. Ann Neurol (2003) 1.15
Laquinimod interferes with migratory capacity of T cells and reduces IL-17 levels, inflammatory demyelination and acute axonal damage in mice with experimental autoimmune encephalomyelitis. J Neuroimmunol (2010) 1.15
Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system. Dis Model Mech (2008) 1.14
Inter-laboratory comparison of neuropathological assessments of beta-amyloid protein: a study of the BrainNet Europe consortium. Acta Neuropathol (2008) 1.13
Microglia promote colonization of brain tissue by breast cancer cells in a Wnt-dependent way. Glia (2010) 1.13
Oligodendrocyte process outgrowth in vitro is modulated by epigenetic regulation of cytoskeletal severing proteins. Glia (2003) 1.13
Evidence for pathogenic heterogeneity in multiple sclerosis. Ann Neurol (2004) 1.10
Epigenetic mechanisms facilitating oligodendrocyte development, maturation, and aging. Glia (2009) 1.09
Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons. Acta Neuropathol (2013) 1.08
Naive CD8 T-cells initiate spontaneous autoimmunity to a sequestered model antigen of the central nervous system. Brain (2008) 1.08
The spectrum of multiple sclerosis: new lessons from pathology. Curr Opin Neurol (2005) 1.07
Assessment of lesion pathology in a new animal model of MS by multiparametric MRI and DTI. Neuroimage (2011) 1.06
Lipopolysaccharide injection induces relapses of experimental autoimmune encephalomyelitis in nontransgenic mice via bystander activation of autoreactive CD4+ cells. J Immunol (2005) 1.06
Oligodendrocyte progenitor proliferation and maturation is differentially regulated by male and female sex steroid hormones. Dev Neurosci (2005) 1.05
Combined therapy with methylprednisolone and erythropoietin in a model of multiple sclerosis. Brain (2004) 1.04
Ligands for PPARgamma and RAR cause induction of growth inhibition and apoptosis in human glioblastomas. J Neurooncol (2003) 1.04
Demyelination arrest and remyelination induced by glatiramer acetate treatment of experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2008) 1.03
Molecular changes in white matter adjacent to an active demyelinating lesion in early multiple sclerosis. Brain Pathol (2008) 1.02
Wallerian degeneration: a major component of early axonal pathology in multiple sclerosis. Brain Pathol (2010) 1.02
Differential upregulation of heme oxygenase-1 (HSP32) in glial cells after oxidative stress and in demyelinating disorders. J Mol Neurosci (2007) 1.02
p27(Kip1) enhances myelin basic protein gene promoter activity. J Neurosci Res (2002) 1.01
Axonal loss and neurofilament phosphorylation changes accompany lesion development and clinical progression in multiple sclerosis. Brain Pathol (2011) 0.98
Expression of the immune-tolerogenic major histocompatibility molecule HLA-G in multiple sclerosis: implications for CNS immunity. Brain (2005) 0.98
Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis. Dis Model Mech (2012) 0.97
Post-translational modifications of nucleosomal histones in oligodendrocyte lineage cells in development and disease. J Mol Neurosci (2008) 0.96
From fish to man: understanding endogenous remyelination in central nervous system demyelinating diseases. Brain (2008) 0.96
Ischemia leads to apoptosis--and necrosis-like neuron death in the ischemic rat hippocampus. Brain Pathol (2004) 0.96
Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions. J Neurosci (2011) 0.95
Inhibition of p53 transcriptional activity: a potential target for future development of therapeutic strategies for primary demyelination. J Neurosci (2008) 0.95
Comparing the pathogenesis of experimental autoimmune encephalomyelitis in CD4-/- and CD8-/- DBA/1 mice defines qualitative roles of different T cell subsets. J Neuroimmunol (2003) 0.94
Prevention of apoptotic but not necrotic cell death following neuronal injury by neurotrophins signaling through the tyrosine kinase receptor. J Neurosurg (2004) 0.94
Early loss of oligodendrocytes in human and experimental neuromyelitis optica lesions. Acta Neuropathol (2013) 0.94
An N-terminally truncated envelope protein encoded by a human endogenous retrovirus W locus on chromosome Xq22.3. Retrovirology (2010) 0.93
"Viral déjà vu" elicits organ-specific immune disease independent of reactivity to self. J Clin Invest (2006) 0.93
Carcinoma cells misuse the host tissue damage response to invade the brain. Glia (2013) 0.92
CCR5Delta32 polymorphism effects on CCR5 expression, patterns of immunopathology and disease course in multiple sclerosis. J Neuroimmunol (2005) 0.92
Events at the transition between cell cycle exit and oligodendrocyte progenitor differentiation: the role of HDAC and YY1. Neuron Glia Biol (2007) 0.91
Neuroaxonal regeneration is more pronounced in early multiple sclerosis than in traumatic brain injury lesions. Brain Pathol (2012) 0.90
Differential macrophage/microglia activation in neocortical EAE lesions in the marmoset monkey. Brain Pathol (2006) 0.90
Bacterial pore-forming cytolysins induce neuronal damage in a rat model of neonatal meningitis. J Infect Dis (2010) 0.89
Number of oligodendrocyte progenitors recruited to the lesioned spinal cord is modulated by the levels of the cell cycle regulatory protein p27Kip-1. Glia (2005) 0.89
Dopamine D3 receptor specifically modulates motor and sensory symptoms in iron-deficient mice. J Neurosci (2011) 0.88
Problems of cell death in neurodegeneration and Alzheimer's Disease. J Alzheimers Dis (2001) 0.88
Increased expression of BDNF and proliferation of dentate granule cells after bacterial meningitis. J Neuropathol Exp Neurol (2005) 0.88
Human glioma-initiating cells show a distinct immature phenotype resembling but not identical to NG2 glia. J Neuropathol Exp Neurol (2013) 0.87
Suppression of autoimmune encephalomyelitis by a neurokinin-1 receptor antagonist--a putative role for substance P in CNS inflammation. J Neuroimmunol (2006) 0.86
Severe spinal muscular atrophy variant associated with congenital bone fractures. J Child Neurol (2002) 0.86
18F-FDG PET detects inflammatory infiltrates in spinal cord experimental autoimmune encephalomyelitis lesions. J Nucl Med (2012) 0.86
Tolerance induction by bone marrow transplantation in a multiple sclerosis model. Blood (2005) 0.85
Fas (CD95/Apo-1)/Fas ligand expression in neonates with pontosubicular neuron necrosis. Pediatr Res (2002) 0.85
Differential regulation of myelin phagocytosis by macrophages/microglia, involvement of target myelin, Fc receptors and activation by intravenous immunoglobulins. J Neurosci Res (2002) 0.84
Deimination restores inner retinal visual function in murine demyelinating disease. J Clin Invest (2013) 0.84
Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord. Ann Neurol (2009) 0.83
PI3Kγ deficiency delays the onset of experimental autoimmune encephalomyelitis and ameliorates its clinical outcome. Eur J Immunol (2011) 0.83
S-phase entry of oligodendrocyte lineage cells is associated with increased levels of p21Cip1. J Neurosci Res (2005) 0.81