Published in Glia on November 15, 2009
MicroRNA-mediated control of oligodendrocyte differentiation. Neuron (2010) 3.24
Epigenetic mechanisms in neurological disease. Nat Med (2012) 1.74
Epigenetic regulation of oligodendrocyte identity. Trends Neurosci (2010) 1.36
Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation. PLoS One (2009) 1.20
Identification of a gene regulatory network necessary for the initiation of oligodendrocyte differentiation. PLoS One (2011) 1.11
Myelin management by the 18.5-kDa and 21.5-kDa classic myelin basic protein isoforms. J Neurochem (2013) 0.96
Genetics meets epigenetics: HDACs and Wnt signaling in myelin development and regeneration. Nat Neurosci (2009) 0.95
Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions. J Neurosci (2011) 0.95
Metabolic acetate therapy improves phenotype in the tremor rat model of Canavan disease. J Inherit Metab Dis (2010) 0.92
Polydendrocytes in development and myelin repair. Neurosci Bull (2013) 0.90
Age-related changes in human and non-human primate white matter: from myelination disturbances to cognitive decline. Age (Dordr) (2011) 0.89
Epigenetic determinants of healthy and diseased brain aging and cognition. JAMA Neurol (2013) 0.88
Extensive aspartoacylase expression in the rat central nervous system. Glia (2011) 0.87
Targeting specific HATs for neurodegenerative disease treatment: translating basic biology to therapeutic possibilities. Front Cell Neurosci (2013) 0.86
Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells. PLoS One (2010) 0.86
The emerging role of epigenetics in stroke: III. Neural stem cell biology and regenerative medicine. Arch Neurol (2011) 0.85
Age-related increase in the number of oligodendrocytes is dysregulated in schizophrenia and mood disorders. Schizophr Res Treatment (2011) 0.84
Neural stem cell differentiation is dictated by distinct actions of nuclear receptor corepressors and histone deacetylases. Stem Cell Reports (2014) 0.83
The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Dev (2015) 0.81
Epigenetics components of aging in the central nervous system. Neurotherapeutics (2013) 0.79
The Autotaxin-Lysophosphatidic Acid Axis Modulates Histone Acetylation and Gene Expression during Oligodendrocyte Differentiation. J Neurosci (2015) 0.78
rAAV Gene Therapy in a Canavan's Disease Mouse Model Reveals Immune Impairments and an Extended Pathology Beyond the Central Nervous System. Mol Ther (2016) 0.78
Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System. J Biol Chem (2015) 0.77
Defining the chromatin landscape in demyelinating disorders. Neurobiol Dis (2009) 0.77
Comparative epigenomics: defining and utilizing epigenomic variations across species, time-course, and individuals. Wiley Interdiscip Rev Syst Biol Med (2014) 0.75
Making the White Matter Matters: Progress in Understanding Canavan's Disease and Therapeutic Interventions Through Eight Decades. JIMD Rep (2015) 0.75
Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature (2006) 25.90
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature (2000) 20.54
The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature (2002) 18.30
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science (2004) 17.38
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet (2005) 17.07
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell (2001) 15.97
Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell (2001) 15.05
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell (2007) 12.72
Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer (2006) 11.48
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J (2004) 11.00
A brain-specific microRNA regulates dendritic spine development. Nature (2006) 10.18
Role of histone H3 lysine 27 methylation in X inactivation. Science (2003) 9.85
MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature (2008) 9.83
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A (2003) 9.14
Mammalian SIRT1 represses forkhead transcription factors. Cell (2004) 8.89
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature (2008) 8.69
Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu Rev Biochem (2006) 8.66
Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells (2005) 6.72
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J (2002) 6.37
Remyelination in the CNS: from biology to therapy. Nat Rev Neurosci (2008) 6.16
Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. Cell (2008) 5.53
Human PAD4 regulates histone arginine methylation levels via demethylimination. Science (2004) 5.46
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol Cell (2004) 5.37
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell (2008) 4.70
Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage. Nat Neurosci (2005) 4.57
Histone ubiquitination: triggering gene activity. Mol Cell (2008) 4.42
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors. Dev Cell (2008) 3.84
Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc Natl Acad Sci U S A (2004) 3.60
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature (2007) 3.55
Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat Neurosci (2008) 3.24
On the use of the word 'epigenetic'. Curr Biol (2007) 3.21
Histone deacetylases, transcriptional control, and cancer. J Cell Physiol (2000) 3.18
Histone deacetylases: unique players in shaping the epigenetic histone code. Ann N Y Acad Sci (2003) 3.05
Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes. J Neurosci (2008) 2.95
Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development (2003) 2.91
Mechanisms involved in the regulation of histone lysine demethylases. Curr Opin Cell Biol (2008) 2.81
Is there a code embedded in proteins that is based on post-translational modifications? Nat Rev Mol Cell Biol (2008) 2.64
MicroRNAs (miRNAs) in neurodegenerative diseases. Brain Pathol (2008) 2.39
Oligodendrocyte wars. Nat Rev Neurosci (2006) 2.39
The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron (2007) 2.38
Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol (2005) 2.34
NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs. Oncogene (2007) 2.29
Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation. Development (2004) 2.21
Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling. Neuron (2005) 2.12
Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain. Neuron (2005) 2.03
Histone deacetylase activity is necessary for oligodendrocyte lineage progression. J Neurosci (2002) 2.00
The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation. J Neurosci (2002) 1.99
Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination. Mol Cell Neurosci (2004) 1.95
The Id4 HLH protein and the timing of oligodendrocyte differentiation. EMBO J (2000) 1.79
Identification of a transcriptional repressor related to the noncatalytic domain of histone deacetylases 4 and 5. Proc Natl Acad Sci U S A (2000) 1.71
FGF2-induced chromatin remodeling regulates CNTF-mediated gene expression and astrocyte differentiation. Nat Neurosci (2004) 1.71
The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis. Neurochem Res (2006) 1.71
Interplay between chromatin remodelers and protein arginine methyltransferases. J Cell Physiol (2007) 1.66
Historical review: the field of protein methylation. Trends Biochem Sci (2007) 1.63
Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development (2006) 1.63
Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J Neurosci (2007) 1.58
Myt1 family recruits histone deacetylase to regulate neural transcription. J Neurochem (2005) 1.54
LSD1 and the chemistry of histone demethylation. Curr Opin Chem Biol (2007) 1.52
Myelin in multiple sclerosis is developmentally immature. J Clin Invest (1994) 1.52
A molecular insight of Hes5-dependent inhibition of myelin gene expression: old partners and new players. EMBO J (2006) 1.49
A matter of identity: transcriptional control in oligodendrocytes. J Mol Neurosci (2007) 1.47
Histone modifications and nuclear architecture: a review. J Histochem Cytochem (2008) 1.42
Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. J Neurosci (2006) 1.41
Transcriptional control of oligodendrogenesis. Glia (2007) 1.39
Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation. Development (2000) 1.39
Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination. Glia (1999) 1.37
Histone H3K4 demethylases are essential in development and differentiation. Biochem Cell Biol (2007) 1.34
The isolation, characterization, and lipid-aggregating properties of a citrulline containing myelin basic protein. J Biol Chem (1989) 1.30
MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2. J Cell Sci (2005) 1.29
Differentiation of neural stem cells into oligodendrocytes: involvement of the polycomb group protein Ezh2. Stem Cells (2008) 1.26
Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells. Proc Natl Acad Sci U S A (2007) 1.26
The glial or neuronal fate choice of oligodendrocyte progenitors is modulated by their ability to acquire an epigenetic memory. J Neurosci (2007) 1.22
Multiple roles of Id4 in developmental myelination: predicted outcomes and unexpected findings. Glia (2006) 1.21
Specification of CNS glia from neural stem cells in the embryonic neuroepithelium. Philos Trans R Soc Lond B Biol Sci (2008) 1.21
Histone deacetylase inhibitors increase neuronal differentiation in adult forebrain precursor cells. Exp Brain Res (2007) 1.19
Nuclear organization in differentiating oligodendrocytes. J Cell Sci (2002) 1.15
Myelin localization of peptidylarginine deiminases 2 and 4: comparison of PAD2 and PAD4 activities. Lab Invest (2008) 1.15
Histone deacetylase 11 regulates oligodendrocyte-specific gene expression and cell development in OL-1 oligodendroglia cells. Glia (2009) 1.15
Deimination of membrane-bound myelin basic protein in multiple sclerosis exposes an immunodominant epitope. Proc Natl Acad Sci U S A (2006) 1.11
Structural dynamics of protein lysine methylation and demethylation. Mutat Res (2007) 1.08
Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated. J Neurosci Res (2007) 1.06
Stage-specific expression of myelin basic protein in oligodendrocytes involves Nkx2.2-mediated repression that is relieved by the Sp1 transcription factor. J Biol Chem (2005) 1.04
Oligodendrocyte differentiation and implantation: new insights for remyelinating cell therapy. Curr Opin Neurol (2008) 1.00
Post-translational modifications of nucleosomal histones in oligodendrocyte lineage cells in development and disease. J Mol Neurosci (2008) 0.96
SIRT2, tubulin deacetylation, and oligodendroglia differentiation. Cell Motil Cytoskeleton (2008) 0.96
Remyelination in multiple sclerosis. Int Rev Neurobiol (2007) 0.94
Histone deacetylase inhibitor 4-phenylbutyrate modulates glial fibrillary acidic protein and connexin 43 expression, and enhances gap-junction communication, in human glioblastoma cells. Eur J Cancer (2004) 0.92
The role of charge microheterogeneity of basic protein in the formation and maintenance of the multilayered structure of myelin: a possible role in multiple sclerosis. J Neurosci Res (1986) 0.92
Events at the transition between cell cycle exit and oligodendrocyte progenitor differentiation: the role of HDAC and YY1. Neuron Glia Biol (2007) 0.91
Evaluating epigenetic landmarks in the brain of multiple sclerosis patients: a contribution to the current debate on disease pathogenesis. Prog Neurobiol (2008) 0.91
Enhanced T cell responsiveness to citrulline-containing myelin basic protein in multiple sclerosis patients. Mult Scler (2000) 0.89
Autocatalytic cleavage of myelin basic protein: an alternative to molecular mimicry. Biochemistry (2005) 0.87
To SIR with Polycomb: linking silencing mechanisms. Bioessays (2005) 0.84
The effects of citrullination or variable amino-terminus acylation on the encephalitogenicity of human myelin basic protein in the PL/J mouse. J Neuroimmunol (1995) 0.80
For a healthy histone code, a little SUMO in the tail keeps the acetyl away. ACS Chem Biol (2006) 0.78
A myelin protein fraction extracted with thioethanol. Brain Res (1972) 0.77
Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat Neurosci (2008) 3.24
The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron (2007) 2.38
Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol (2005) 2.34
Mutations in potassium channel kcnd3 cause spinocerebellar ataxia type 19. Ann Neurol (2012) 1.70
The Yin and Yang of YY1 in the nervous system. J Neurochem (2008) 1.68
Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J Neurosci (2007) 1.58
Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS. Mech Dev (2005) 1.53
A molecular insight of Hes5-dependent inhibition of myelin gene expression: old partners and new players. EMBO J (2006) 1.49
Lack of the cell-cycle inhibitor p27Kip1 results in selective increase of transit-amplifying cells for adult neurogenesis. J Neurosci (2002) 1.48
Combinatorial profiles of oligodendrocyte-selective classes of transcriptional regulators differentially modulate myelin basic protein gene expression. J Neurosci (2005) 1.47
Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. J Neurosci (2006) 1.41
Differentiation of neural stem cells into oligodendrocytes: involvement of the polycomb group protein Ezh2. Stem Cells (2008) 1.26
Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation. EMBO J (2003) 1.25
The glial or neuronal fate choice of oligodendrocyte progenitors is modulated by their ability to acquire an epigenetic memory. J Neurosci (2007) 1.22
Epigenetic memory loss in aging oligodendrocytes in the corpus callosum. Neurobiol Aging (2006) 1.21
Multiple roles of Id4 in developmental myelination: predicted outcomes and unexpected findings. Glia (2006) 1.21
Olig2 overexpression induces the in vitro differentiation of neural stem cells into mature oligodendrocytes. Stem Cells (2005) 1.13
Oligodendrocyte process outgrowth in vitro is modulated by epigenetic regulation of cytoskeletal severing proteins. Glia (2003) 1.13
Oligodendrocyte progenitor proliferation and maturation is differentially regulated by male and female sex steroid hormones. Dev Neurosci (2005) 1.05
Differentiation of induced pluripotent stem cells into functional oligodendrocytes. Glia (2011) 1.04
p27(Kip1) enhances myelin basic protein gene promoter activity. J Neurosci Res (2002) 1.01
Bioluminescence imaging of Olig2-neural stem cells reveals improved engraftment in a demyelination mouse model. Stem Cells (2009) 1.00
Oligodendrocyte differentiation and implantation: new insights for remyelinating cell therapy. Curr Opin Neurol (2008) 1.00
What is microglia neurotoxicity (Not)? Glia (2014) 0.99
Dynamic changes in Ezh2 gene occupancy underlie its involvement in neural stem cell self-renewal and differentiation towards oligodendrocytes. PLoS One (2012) 0.96
Post-translational modifications of nucleosomal histones in oligodendrocyte lineage cells in development and disease. J Mol Neurosci (2008) 0.96
Inhibition of p53 transcriptional activity: a potential target for future development of therapeutic strategies for primary demyelination. J Neurosci (2008) 0.95
Prevention of apoptotic but not necrotic cell death following neuronal injury by neurotrophins signaling through the tyrosine kinase receptor. J Neurosurg (2004) 0.94
Events at the transition between cell cycle exit and oligodendrocyte progenitor differentiation: the role of HDAC and YY1. Neuron Glia Biol (2007) 0.91
Ezh2 expression in astrocytes induces their dedifferentiation toward neural stem cells. Cell Reprogram (2010) 0.91
Expression of stathmin, a developmentally controlled cytoskeleton-regulating molecule, in demyelinating disorders. J Neurosci (2005) 0.89
Number of oligodendrocyte progenitors recruited to the lesioned spinal cord is modulated by the levels of the cell cycle regulatory protein p27Kip-1. Glia (2005) 0.89
Intraventricularly injected Olig2-NSCs attenuate established relapsing-remitting EAE in mice. Cell Transplant (2012) 0.86
Alpha-B-crystallin induces an immune-regulatory and antiviral microglial response in preactive multiple sclerosis lesions. J Neuropathol Exp Neurol (2013) 0.85
Transient expression of Olig1 initiates the differentiation of neural stem cells into oligodendrocyte progenitor cells. Stem Cells (2004) 0.84
The L450F [Corrected] mutation in KCND3 brings spinocerebellar ataxia and Brugada syndrome closer together. Neurogenetics (2013) 0.83
Deficient p75 low-affinity neurotrophin receptor expression exacerbates experimental allergic encephalomyelitis in C57/BL6 mice. J Neuroimmunol (2004) 0.83
Absence of colossal magnetoresistance in the oxypnictide PrMnAsO0.95F0.05. Inorg Chem (2015) 0.82
Immune cell dynamics in the CNS: Learning from the zebrafish. Glia (2014) 0.82
Activation of an immune-regulatory macrophage response and inhibition of lung inflammation in a mouse model of COPD using heat-shock protein alpha B-crystallin-loaded PLGA microparticles. Biomaterials (2012) 0.81
Human oligodendrocytes in remyelination research. Glia (2014) 0.81
S-phase entry of oligodendrocyte lineage cells is associated with increased levels of p21Cip1. J Neurosci Res (2005) 0.81
Induced pluripotent stem cell technology and direct conversion: new possibilities to study and treat Parkinson's disease. Stem Cell Rev (2013) 0.79
Spinocerebellar ataxia type 19/22 mutations alter heterocomplex Kv4.3 channel function and gating in a dominant manner. Cell Mol Life Sci (2015) 0.79
Interplay of hormones and p53 in modulating gender dimorphism of subventricular zone cell number. J Neurosci Res (2009) 0.78
Deficient p75 low-affinity neurotrophin receptor expression does alter the composition of cellular infiltrate in experimental autoimmune encephalomyelitis in C57BL/6 mice. J Neuroimmunol (2006) 0.78
Pluripotent stem cells for Schwann cell engineering. Stem Cell Rev (2015) 0.76
In vivo bioluminescent imaging of Schwann cells in a poly(DL-lactide-epsilon-caprolactone) nerve guide. Muscle Nerve (2009) 0.75
Chemical tuning of positive and negative magnetoresistances, and superconductivity in 1222-type ruthenocuprates. J Am Chem Soc (2006) 0.75
Generation of induced pluripotent stem cells from hair follicle bulge neural crest stem cells. Cell Reprogram (2014) 0.75
"Hard-soft" synthesis of SrCrO3-δ superstructure phases. Angew Chem Int Ed Engl (2012) 0.75