Published in Nat Rev Cancer on February 01, 2005
Replication licensing and cancer--a fatal entanglement? Nat Rev Cancer (2008) 2.86
Loss of DNA replication control is a potent inducer of gene amplification. Science (2010) 2.02
Identification of novel alternative splice isoforms of circulating proteins in a mouse model of human pancreatic cancer. Cancer Res (2009) 1.40
Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote s-phase genome stability. Mol Cell Biol (2008) 1.21
Aurora kinase A outperforms Ki67 as a prognostic marker in ER-positive breast cancer. Br J Cancer (2012) 1.15
Nuclear transfer to eggs and oocytes. Cold Spring Harb Perspect Biol (2011) 1.13
DNA licensing as a novel androgen receptor mediated therapeutic target for prostate cancer. Endocr Relat Cancer (2009) 1.12
Cell-cycle-phase progression analysis identifies unique phenotypes of major prognostic and predictive significance in breast cancer. Br J Cancer (2009) 1.04
KLF15 negatively regulates estrogen-induced epithelial cell proliferation by inhibition of DNA replication licensing. Proc Natl Acad Sci U S A (2012) 1.04
Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease. Aging (Albany NY) (2009) 1.01
DNA replication stress response involving PLK1, CDC6, POLQ, RAD51 and CLASPIN upregulation prognoses the outcome of early/mid-stage non-small cell lung cancer patients. Oncogenesis (2012) 1.00
Replication forks, chromatin loops and dormant replication origins. Genome Biol (2008) 0.96
A minimally invasive immunocytochemical approach to early detection of oral squamous cell carcinoma and dysplasia. Br J Cancer (2006) 0.94
MCM immunocytochemistry as a first line cervical screening test in developing countries: a prospective cohort study in a regional cancer centre in India. Br J Cancer (2007) 0.93
Replication licensing and the DNA damage checkpoint. Front Biosci (Landmark Ed) (2009) 0.90
Dbf4 and Cdc7 proteins promote DNA replication through interactions with distinct Mcm2-7 protein subunits. J Biol Chem (2013) 0.89
Characterization of the Tyrosine Kinase-Regulated Proteome in Breast Cancer by Combined use of RNA interference (RNAi) and Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) Quantitative Proteomics. Mol Cell Proteomics (2015) 0.87
Role of protein biomarkers in the detection of high-grade disease in cervical cancer screening programs. J Oncol (2012) 0.87
Prognostic significance of minichromosome maintenance proteins in breast cancer. Am J Cancer Res (2014) 0.86
Nuclear reprogramming in eggs. Nat Med (2009) 0.86
DNA replication licensing control and rereplication prevention. Protein Cell (2010) 0.83
Replication proteins and human disease. Cold Spring Harb Perspect Biol (2014) 0.82
Transient association of MCM complex proteins with the nuclear matrix during initiation of mammalian DNA replication. Cell Cycle (2015) 0.79
Diagnosis of bladder cancer by immunocytochemical detection of minichromosome maintenance protein-2 in cells retrieved from urine. Br J Cancer (2012) 0.79
The Role of Proteomics in the Diagnosis and Treatment of Women's Cancers: Current Trends in Technology and Future Opportunities. Int J Proteomics (2011) 0.78
Flipping the switch from g1 to s phase with e3 ubiquitin ligases. Genes Cancer (2012) 0.78
Initiation of DNA Replication in the Human Genome. Hereditary Genet (2012) 0.77
Defective denominators. Gut (2005) 0.75
Diagnostic value of MCM2 immunocytochemical staining in cervical lesions and its relationship with HPV infection. Int J Clin Exp Pathol (2015) 0.75
A quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations. BMC Syst Biol (2012) 0.75
Expression Analysis of Genes Involved in the RB/E2F Pathway in Astrocytic Tumors. PLoS One (2015) 0.75
Evaluation of Minichromosome Maintenance-3 (MCM3) in Oral Squamous Cell Carcinoma. J Dent (Shiraz) (2015) 0.75
Simvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth. Cell Death Dis (2017) 0.75
Promotion of cell proliferation by the proto-oncogene DEK enhances oral squamous cell carcinogenesis through field cancerization. Cancer Med (2017) 0.75
Expression of cell cycle markers is predictive of the response to primary systemic therapy of locally advanced breast cancer. Virchows Arch (2016) 0.75
Organization of the archaeal MCM complex on DNA and implications for the helicase mechanism. Nat Struct Mol Biol (2005) 3.04
Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro. J Leukoc Biol (2002) 2.93
Distinct roles for cyclins E and A during DNA replication complex assembly and activation. Nat Cell Biol (2002) 2.55
Histological changes in HCV antibody-positive, HCV RNA-negative subjects suggest persistent virus infection. Hepatology (2008) 2.21
The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel. Cancer Cell (2007) 2.05
Compromised lymphocytes infiltrate hepatocellular carcinoma: the role of T-regulatory cells. Hepatology (2005) 2.04
Organization of human papillomavirus productive cycle during neoplastic progression provides a basis for selection of diagnostic markers. J Virol (2003) 1.79
Tumour lymphocytic infiltrate and recurrence of hepatocellular carcinoma following liver transplantation. J Hepatol (2006) 1.69
Colorectal cancer screening: prospects for molecular stool analysis. Nat Rev Cancer (2005) 1.64
Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets. Cancer Res (2010) 1.59
Acquisition of high-level chromosomal instability is associated with integration of human papillomavirus type 16 in cervical keratinocytes. Cancer Res (2004) 1.56
FUS/ERG gene fusions in Ewing's tumors. Cancer Res (2003) 1.50
Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. Genes Dev (2006) 1.49
Tumor recurrence following liver transplantation for hepatocellular carcinoma: role of tumor proliferation status. Liver Transpl (2010) 1.44
Cell-cycle-dependent regulation of DNA replication and its relevance to cancer pathology. J Pathol (2005) 1.44
A novel immunohistochemical method to estimate cell-cycle phase distribution in archival tissue: implications for the prediction of outcome in colorectal cancer. J Pathol (2003) 1.40
Relation between hepatocyte G1 arrest, impaired hepatic regeneration, and fibrosis in chronic hepatitis C virus infection. Gastroenterology (2005) 1.38
Geminin predicts adverse clinical outcome in breast cancer by reflecting cell-cycle progression. J Pathol (2004) 1.37
Changes in cervical keratinocyte gene expression associated with integration of human papillomavirus 16. Cancer Res (2002) 1.34
Selection of cervical keratinocytes containing integrated HPV16 associates with episome loss and an endogenous antiviral response. Proc Natl Acad Sci U S A (2006) 1.31
Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1. EMBO J (2003) 1.28
Surface expression of minichromosome maintenance proteins provides a novel method for detecting patients at risk for developing adenocarcinoma in Barrett's esophagus. Clin Cancer Res (2003) 1.26
A prospective study on the natural course of low-grade squamous intraepithelial lesions and the presence of HPV16 E2-, E6- and E7-specific T-cell responses. Int J Cancer (2010) 1.25
Analysis of minichromosome maintenance proteins as a novel method for detection of colorectal cancer in stool. Lancet (2002) 1.24
Minichromosome maintenance protein 2 is a strong independent prognostic marker in breast cancer. J Clin Oncol (2003) 1.24
Geminin escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and Nanog. Curr Biol (2011) 1.24
Minichromosome maintenance protein 2 expression in normal kidney and renal cell carcinomas: relationship to tumor dormancy and potential clinical utility. Clin Cancer Res (2002) 1.19
Identification of microRNAs From the miR-371~373 and miR-302 clusters as potential serum biomarkers of malignant germ cell tumors. Am J Clin Pathol (2011) 1.19
Characterization of naturally occurring HPV16 integration sites isolated from cervical keratinocytes under noncompetitive conditions. Cancer Res (2008) 1.17
Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export. Nucleic Acids Res (2012) 1.15
Vaccinia-expressed human papillomavirus 16 and 18 e6 and e7 as a therapeutic vaccination for vulval and vaginal intraepithelial neoplasia. Clin Cancer Res (2003) 1.12
Interferon-beta treatment of cervical keratinocytes naturally infected with human papillomavirus 16 episomes promotes rapid reduction in episome numbers and emergence of latent integrants. Carcinogenesis (2006) 1.11
mRNA export from mammalian cell nuclei is dependent on GANP. Curr Biol (2009) 1.11
Translational approaches to improving cervical screening. Nat Rev Cancer (2003) 1.10
In vitro progression of human papillomavirus 16 episome-associated cervical neoplasia displays fundamental similarities to integrant-associated carcinogenesis. Cancer Res (2010) 1.10
Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects. EMBO Rep (2005) 1.10
In vitro acid exposure has a differential effect on apoptotic and proliferative pathways in a Barrett's adenocarcinoma cell line. Am J Gastroenterol (2004) 1.07
Functional evidence that Drosha overexpression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles. J Pathol (2011) 1.07
Pediatric malignant germ cell tumors show characteristic transcriptome profiles. Cancer Res (2008) 1.03
Expression of human immunodeficiency virus (HIV)-binding lectin DC-SIGNR: Consequences for HIV infection and immunity. Hum Pathol (2002) 1.03
Regulatable killing of eukaryotic cells by the prokaryotic proteins Kid and Kis. EMBO J (2003) 1.02
Somatic genetic changes accompanying lung tumor development. Genes Chromosomes Cancer (2005) 1.00
Human replication protein Cdc6 is selectively cleaved by caspase 3 during apoptosis. EMBO Rep (2002) 0.97
Targeted serum miRNA (TSmiR) test for diagnosis and follow-up of (testicular) germ cell cancer patients: a proof of principle. Mol Oncol (2013) 0.96
Immunohistochemical estimation of cell cycle entry and phase distribution in astrocytomas: applications in diagnostic neuropathology. Neuropathol Appl Neurobiol (2005) 0.94
The two most common histological subtypes of malignant germ cell tumour are distinguished by global microRNA profiles, associated with differential transcription factor expression. Mol Cancer (2010) 0.94
Critical evaluation of HPV16 gene copy number quantification by SYBR green PCR. BMC Biotechnol (2008) 0.93
LIN28 Expression in malignant germ cell tumors downregulates let-7 and increases oncogene levels. Cancer Res (2013) 0.92
Human inositol polyphosphate multikinase regulates transcript-selective nuclear mRNA export to preserve genome integrity. Mol Cell (2013) 0.92
Oncostatin M receptor is a novel therapeutic target in cervical squamous cell carcinoma. J Pathol (2014) 0.91
Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP. Nucleic Acids Res (2014) 0.89
Pathogenesis of human papillomavirus-associated mucosal disease. J Pathol (2015) 0.89
Improved screening for anal neoplasia by immunocytochemical detection of minichromosome maintenance proteins. Cancer Epidemiol Biomarkers Prev (2008) 0.88
Familial rhabdoid tumour 'avant la lettre'--from pathology review to exome sequencing and back again. J Pathol (2013) 0.88
Cell cycle phase abnormalities do not account for disordered proliferation in Barrett's carcinogenesis. Neoplasia (2005) 0.88
Overexpression of the oncostatin M receptor in cervical squamous cell carcinoma cells is associated with a pro-angiogenic phenotype and increased cell motility and invasiveness. J Pathol (2011) 0.87
Testicular cancer: a new generation of biomarkers for malignant germ cell tumours. Nat Rev Urol (2012) 0.86
Heterogeneous inflammatory changes in liver graft recipients with normal biochemistry. Transplantation (2010) 0.84
Hepatocyte expression of minichromosome maintenance protein-2 predicts fibrosis progression after transplantation for chronic hepatitis C virus: a pilot study. Liver Transpl (2005) 0.83
Serum microRNA screening for DICER1-associated pleuropulmonary blastoma. Pediatr Blood Cancer (2014) 0.83
Depletion of HPV16 early genes induces autophagy and senescence in a cervical carcinogenesis model, regardless of viral physical state. J Pathol (2013) 0.83
Tissue transglutaminase mediates the pro-malignant effects of oncostatin M receptor over-expression in cervical squamous cell carcinoma. J Pathol (2013) 0.83
Defining ploidy-specific thresholds in array comparative genomic hybridization to improve the sensitivity of detection of single copy alterations in cell lines. J Mol Diagn (2006) 0.83
Replication proteins and human disease. Cold Spring Harb Perspect Biol (2014) 0.82
Myxofibrosarcomas contain large numbers of infiltrating immature dendritic cells. Am J Clin Pathol (2003) 0.82
Isolation of stool-derived mucus provides a high yield of colonocytes suitable for early detection of colorectal carcinoma. Cancer Epidemiol Biomarkers Prev (2009) 0.81
Minichromosome maintenance protein in myxofibrosarcoma. Mod Pathol (2004) 0.81
Management of irritable bowel syndrome in primary care: the results of an exploratory randomised controlled trial of mebeverine, methylcellulose, placebo and a self-management website. BMC Gastroenterol (2013) 0.81
Virus transcript levels and cell growth rates after naturally occurring HPV16 integration events in basal cervical keratinocytes. J Pathol (2014) 0.80
Structural genomic abnormalities of chromosomes 9 and 18 in myxopapillary ependymomas. J Neuropathol Exp Neurol (2003) 0.80
MCM3AP is transcribed from a promoter within an intron of the overlapping gene for GANP. J Mol Biol (2010) 0.80
Transplacental transmission of HIV: a potential role for HIV binding lectins. Int J Biochem Cell Biol (2003) 0.80
Evaluation of 3 methods of whole-genome amplification for subsequent metaphase comparative genomic hybridization. Diagn Mol Pathol (2005) 0.80
Distinct activities of the anaphase-promoting complex/cyclosome (APC/C) in mouse embryonic cells. Cell Cycle (2012) 0.79
Depletion of polycistronic transcripts using short interfering RNAs: cDNA synthesis method affects levels of non-targeted genes determined by quantitative PCR. Virol J (2013) 0.79
Minichromosome maintenance protein-2-positive portal tract lymphocytes distinguish acute cellular rejection from hepatitis C virus recurrence after liver transplantation. Liver Transpl (2009) 0.79
Variable methylation of the imprinted gene, SNRPN, supports a relationship between intracranial germ cell tumours and neural stem cells. J Neurooncol (2010) 0.79
GANP enhances the efficiency of mRNA nuclear export in mammalian cells. Nucleus (2011) 0.79
Re: Characterization of the A673 cell line (Ewing tumor) by molecular cytogenetic techniques. Cancer Genet Cytogenet (2004) 0.79
Paint-assisted microdissection-FISH: Rapid and simple mapping of translocation breakpoints in the embryonal rhabdomyosarcoma cell line RD. Cytometry A (2004) 0.79
Screening for colorectal cancer using stool. Discov Med (2005) 0.77
Minichromosome maintenance proteins in cancer screening. Eur J Cancer (2009) 0.76
A high-throughput computational framework for identifying significant copy number aberrations from array comparative genomic hybridisation data. Adv Bioinformatics (2012) 0.76
Xenopus cell-free extracts and their contribution to the study of DNA replication and other complex biological processes. Int J Dev Biol (2016) 0.76
Age-related biological features of germ cell tumors. Genes Chromosomes Cancer (2013) 0.75
Correction: Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis. PLoS One (2015) 0.75
Incidence of facial clefts in Cambridge, United Kingdom. Eur J Orthod (2010) 0.75
No cause for alarm in IBS. Practitioner (2002) 0.75