Published in Immunol Rev on February 01, 2005
Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IκBα deficiency. Clin Microbiol Rev (2011) 2.08
Hypomorphic nuclear factor-kappaB essential modulator mutation database and reconstitution system identifies phenotypic and immunologic diversity. J Allergy Clin Immunol (2008) 1.93
The X chromosome in immune functions: when a chromosome makes the difference. Nat Rev Immunol (2010) 1.71
Update on the hyper immunoglobulin M syndromes. Br J Haematol (2010) 1.43
Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease. Proc Natl Acad Sci U S A (2016) 1.41
Toll-like receptor 7 and 9 defects in common variable immunodeficiency. J Allergy Clin Immunol (2009) 1.26
Dental and oral anomalies in incontinentia pigmenti: a systematic review. Clin Oral Investig (2012) 1.07
Development of a clinical assay to evaluate toll-like receptor function. Clin Vaccine Immunol (2006) 1.06
Autoimmunity in hyper-IgM syndrome. J Clin Immunol (2008) 1.06
IKBKG (nuclear factor-kappa B essential modulator) mutation can be associated with opportunistic infection without impairing Toll-like receptor function. J Allergy Clin Immunol (2008) 1.03
Opposing roles of NF-kappaB family members in the regulation of NK cell proliferation and production of IFN-gamma. Int Immunol (2006) 1.01
Haploinsufficiency of the NF-κB1 Subunit p50 in Common Variable Immunodeficiency. Am J Hum Genet (2015) 1.00
NEMO is a key component of NF-κB- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus. J Allergy Clin Immunol (2011) 0.96
Immune deficiency caused by impaired expression of nuclear factor-kappaB essential modifier (NEMO) because of a mutation in the 5' untranslated region of the NEMO gene. J Allergy Clin Immunol (2010) 0.96
Cell penetrating peptide inhibitors of nuclear factor-kappa B. Cell Mol Life Sci (2008) 0.95
Kruppel-like factor 2 is a transcriptional regulator of chronic and acute inflammation. Am J Pathol (2013) 0.94
NF-kappaB-dependent induction of cathelicidin-related antimicrobial peptide in murine mast cells by lipopolysaccharide. Int Arch Allergy Immunol (2009) 0.94
Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndrome. Clin Immunol (2009) 0.92
Molecular immunity to mycobacteria: knowledge from the mutation and phenotype spectrum analysis of Mendelian susceptibility to mycobacterial diseases. Int J Infect Dis (2011) 0.89
A novel gain-of-function IKBA mutation underlies ectodermal dysplasia with immunodeficiency and polyendocrinopathy. J Clin Immunol (2013) 0.86
The zinc finger domain of IKKγ (NEMO) protein in health and disease. J Cell Mol Med (2010) 0.85
The cell biology of cryptosporidium infection. Microbes Infect (2011) 0.84
Retracted HIV-1 Nef inhibits lipopolysaccharide-induced IL-12p40 expression by inhibiting JNK-activated NFkappaB in human monocytic cells. J Biol Chem (2008) 0.82
Immune microenvironment as a factor of breast cancer progression. Diagn Pathol (2015) 0.81
Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα. J Exp Med (2015) 0.79
Involvement of and interaction between WNT10A and EDA mutations in tooth agenesis cases in the Chinese population. PLoS One (2013) 0.78
A disorder-induced domino-like destabilization mechanism governs the folding and functional dynamics of the repeat protein IκBα. PLoS Comput Biol (2013) 0.78
Hypohidrotic ectodermal dysplasia and immunodeficiency with coincident NEMO and EDA mutations. Front Immunol (2011) 0.75
Unbalanced Immune System: Immunodeficiencies and Autoimmunity. Front Pediatr (2016) 0.75
Normal human CD4(+) helper T cells express Kv1.1 voltage-gated K(+) channels, and selective Kv1.1 block in T cells induces by itself robust TNFα production and secretion and activation of the NFκB non-canonical pathway. J Neural Transm (Vienna) (2015) 0.75
TACI is mutant in common variable immunodeficiency and IgA deficiency. Nat Genet (2005) 4.08
Transcellular diapedesis is initiated by invasive podosomes. Immunity (2007) 4.06
Primary immunodeficiencies: 2009 update. J Allergy Clin Immunol (2009) 3.70
TACI and BAFF-R mediate isotype switching in B cells. J Exp Med (2005) 3.31
Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency. Front Immunol (2011) 3.05
Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J Exp Med (2007) 2.85
Impaired IgA class switching in APRIL-deficient mice. Proc Natl Acad Sci U S A (2004) 2.57
The mature activating natural killer cell immunologic synapse is formed in distinct stages. Proc Natl Acad Sci U S A (2003) 2.56
Primary immune deficiencies with aberrant IgE production. J Allergy Clin Immunol (2008) 2.38
Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. J Immunol (2008) 2.38
Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP. Mol Cell Biol (2004) 2.36
Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses. Proc Natl Acad Sci U S A (2002) 2.32
Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency. Medicine (Baltimore) (2010) 2.26
TSLP acts on infiltrating effector T cells to drive allergic skin inflammation. Proc Natl Acad Sci U S A (2008) 2.22
Challenges in infant immunity: implications for responses to infection and vaccines. Nat Immunol (2011) 2.17
Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals. Cell (2008) 2.13
Innate immune function by Toll-like receptors: distinct responses in newborns and the elderly. Immunity (2012) 2.08
TCR zeta down-regulation under chronic inflammation is mediated by myeloid suppressor cells differentially distributed between various lymphatic organs. J Immunol (2006) 2.05
C4b-binding protein (C4BP) activates B cells through the CD40 receptor. Immunity (2003) 2.04
Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia. Proc Natl Acad Sci U S A (2002) 2.01
Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists. Blood (2008) 1.94
Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen. J Allergy Clin Immunol (2009) 1.91
Disseminated varicella infection due to the vaccine strain of varicella-zoster virus, in a patient with a novel deficiency in natural killer T cells. J Infect Dis (2003) 1.91
Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane. J Cell Biol (2005) 1.91
Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations. J Clin Invest (2002) 1.83
Animal models of atopic dermatitis. J Invest Dermatol (2009) 1.80
Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB. Int Immunol (2004) 1.79
Mechanical injury polarizes skin dendritic cells to elicit a T(H)2 response by inducing cutaneous thymic stromal lymphopoietin expression. J Allergy Clin Immunol (2010) 1.78
Neonatal babesiosis: case report and review of the literature. Pediatr Infect Dis J (2006) 1.78
The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity. Proc Natl Acad Sci U S A (2009) 1.77
CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation. J Clin Invest (2002) 1.73
DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nat Immunol (2012) 1.70
WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP). Proc Natl Acad Sci U S A (2007) 1.70
Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation. Mol Cell (2002) 1.70
Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge. Proc Natl Acad Sci U S A (2007) 1.60
Innate immunity of the human newborn is polarized toward a high ratio of IL-6/TNF-alpha production in vitro and in vivo. Pediatr Res (2006) 1.59
Dominant-negative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID). J Clin Invest (2007) 1.58
Neck injury and fibromyalgia-- are they really associated? J Rheumatol (2006) 1.56
Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP. Blood (2009) 1.52
Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function. J Exp Med (2014) 1.49
A novel homozygous mutation in recombination activating gene 2 in 2 relatives with different clinical phenotypes: Omenn syndrome and hyper-IgM syndrome. J Allergy Clin Immunol (2012) 1.48
Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee Meeting in Budapest, 2005. J Allergy Clin Immunol (2006) 1.46
Human nuclear factor kappa B essential modulator mutation can result in immunodeficiency without ectodermal dysplasia. J Allergy Clin Immunol (2004) 1.43
Cellular and molecular mechanisms in atopic dermatitis. Adv Immunol (2009) 1.41
WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation. Immunity (2002) 1.41
The presentation and natural history of immunodeficiency caused by nuclear factor kappaB essential modulator mutation. J Allergy Clin Immunol (2004) 1.40
Role of innate host defenses in susceptibility to early-onset neonatal sepsis. Clin Perinatol (2010) 1.39
Management of first-time dislocations of the shoulder in patients older than 40 years: the prevalence of iatrogenic fracture. J Orthop Trauma (2013) 1.39
IL-10 is critical for Th2 responses in a murine model of allergic dermatitis. J Clin Invest (2003) 1.36
RIP links TLR4 to Akt and is essential for cell survival in response to LPS stimulation. J Exp Med (2004) 1.35
Developmental biology of the innate immune response: implications for neonatal and infant vaccine development. Pediatr Res (2009) 1.33
WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1alpha. Int Immunol (2005) 1.32
Defective actin accumulation impairs human natural killer cell function in patients with dedicator of cytokinesis 8 deficiency. J Allergy Clin Immunol (2013) 1.31
A phenotypic approach for IUIS PID classification and diagnosis: guidelines for clinicians at the bedside. J Clin Immunol (2013) 1.27
B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice. Blood (2012) 1.27
LPS-responsive beige-like anchor (LRBA) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency. J Allergy Clin Immunol (2012) 1.26
Wiskott-Aldrich syndrome: a comprehensive review. Ann N Y Acad Sci (2013) 1.25
Successful engraftment of donor marrow after allogeneic hematopoietic cell transplantation in autosomal-recessive hyper-IgE syndrome caused by dedicator of cytokinesis 8 deficiency. J Allergy Clin Immunol (2010) 1.24
Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response. Proc Natl Acad Sci U S A (2009) 1.23
Complexes of HLA-G protein on the cell surface are important for leukocyte Ig-like receptor-1 function. J Immunol (2003) 1.23
Age-dependent maturation of Toll-like receptor-mediated cytokine responses in Gambian infants. PLoS One (2011) 1.22
Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13. J Allergy Clin Immunol (2009) 1.22
Thymic stromal lymphopoietin. Ann N Y Acad Sci (2010) 1.21
The H1 histamine receptor regulates allergic lung responses. J Clin Invest (2006) 1.21
Epicutaneous sensitization with superantigen induces allergic skin inflammation. J Allergy Clin Immunol (2003) 1.20
Differential role of SLP-76 domains in T cell development and function. Proc Natl Acad Sci U S A (2002) 1.20
Safety and efficacy of neonatal vaccination. Eur J Immunol (2009) 1.17
IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice. J Clin Invest (2008) 1.17
Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation. J Allergy Clin Immunol (2007) 1.17
Role of innate immunity in neonatal infection. Am J Perinatol (2013) 1.16
3BP2 deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation. Mol Cell Biol (2006) 1.13
Arthroscopic management of the painful snapping scapula. Arthroscopy (2006) 1.11
WIP participates in actin reorganization and ruffle formation induced by PDGF. J Cell Sci (2003) 1.10
Leukotriene B4-driven neutrophil recruitment to the skin is essential for allergic skin inflammation. Immunity (2012) 1.09
Development of newborn and infant vaccines. Sci Transl Med (2011) 1.09
Plasma-mediated immune suppression: a neonatal perspective. Pediatr Allergy Immunol (2012) 1.09
Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1-dependent pathways. J Allergy Clin Immunol (2012) 1.09
Aspartame: review of safety. Regul Toxicol Pharmacol (2002) 1.08
The C104R mutant impairs the function of transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) through haploinsufficiency. J Allergy Clin Immunol (2010) 1.08
WIP regulates signaling via the high affinity receptor for immunoglobulin E in mast cells. J Exp Med (2004) 1.07
Epicutaneous challenge of orally immunized mice redirects antigen-specific gut-homing T cells to the skin. J Clin Invest (2011) 1.06
Impaired immune response to vaccinia virus inoculated at the site of cutaneous allergic inflammation. J Allergy Clin Immunol (2007) 1.05
Operative management of the frozen shoulder in patients with diabetes. J Shoulder Elbow Surg (2002) 1.05
Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome. J Allergy Clin Immunol (2005) 1.05
The murine equivalent of the A181E TACI mutation associated with common variable immunodeficiency severely impairs B-cell function. Blood (2009) 1.04
TLR2 mediates recognition of live Staphylococcus epidermidis and clearance of bacteremia. PLoS One (2010) 1.04
Targeted inactivation of the IL-4 receptor alpha chain I4R motif promotes allergic airway inflammation. J Exp Med (2003) 1.04
IPEX and the role of Foxp3 in the development and function of human Tregs. J Clin Invest (2006) 1.04
Neonatal plasma polarizes TLR4-mediated cytokine responses towards low IL-12p70 and high IL-10 production via distinct factors. PLoS One (2012) 1.04
The role of arthroscopy for the problem shoulder arthroplasty. J Shoulder Elbow Surg (2002) 1.03
The ultra-potent and selective TLR8 agonist VTX-294 activates human newborn and adult leukocytes. PLoS One (2013) 1.03
The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen. J Clin Invest (2004) 1.03
Molecular basis of common variable immunodeficiency. J Allergy Clin Immunol (2006) 1.03
Heterozygous N-terminal deletion of IkappaBalpha results in functional nuclear factor kappaB haploinsufficiency, ectodermal dysplasia, and immune deficiency. J Allergy Clin Immunol (2007) 1.03
Geometrical analysis of Copeland surface replacement shoulder arthroplasty in relation to normal anatomy. J Shoulder Elbow Surg (2005) 1.02
A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP. J Exp Med (2012) 1.02
Mast cells regulate IFN-gamma expression in the skin and circulating IgE levels in allergen-induced skin inflammation. J Allergy Clin Immunol (2002) 1.02
Systemic stimulation of TLR2 impairs neonatal mouse brain development. PLoS One (2011) 1.02