Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists.

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Published in Blood on June 30, 2008

Authors

James L Wynn1, Philip O Scumpia, Robert D Winfield, Matthew J Delano, Kindra Kelly-Scumpia, Tolga Barker, Ricardo Ungaro, Ofer Levy, Lyle L Moldawer

Author Affiliations

1: Department of Surgery, University of Florida College of Medicine, Gainesville, FL 32610-0286, USA.

Associated clinical trials:

Novel Mechanisms and Approaches to Treat Neonatal Sepsis | NCT02554630

Microfluidic Assessment of Clinical Outcomes in Preterm Newborns | NCT03291496

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