Published in Trends Genet on February 01, 2005
A mammalian microRNA expression atlas based on small RNA library sequencing. Cell (2007) 34.03
Functions and regulation of RNA editing by ADAR deaminases. Annu Rev Biochem (2010) 5.99
Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat Biotechnol (2012) 3.83
Editor meets silencer: crosstalk between RNA editing and RNA interference. Nat Rev Mol Cell Biol (2006) 3.31
Alu element-mediated gene silencing. EMBO J (2008) 3.22
Frequency and fate of microRNA editing in human brain. Nucleic Acids Res (2008) 2.77
Altered adenosine-to-inosine RNA editing in human cancer. Genome Res (2007) 2.38
Alu elements as regulators of gene expression. Nucleic Acids Res (2006) 2.31
Genetic variation in the zebrafish. Genome Res (2006) 2.22
A survey of genomic traces reveals a common sequencing error, RNA editing, and DNA editing. PLoS Genet (2010) 1.81
RNA-editing-mediated exon evolution. Genome Biol (2007) 1.77
RNA editing level in the mouse is determined by the genomic repeat repertoire. RNA (2006) 1.75
The expanding transcriptome: the genome as the 'Book of Sand'. EMBO J (2006) 1.73
High levels of RNA-editing site conservation amongst 15 laboratory mouse strains. Genome Biol (2012) 1.68
Adenosine-to-inosine RNA editing shapes transcriptome diversity in primates. Proc Natl Acad Sci U S A (2010) 1.47
Systematic identification of edited microRNAs in the human brain. Genome Res (2012) 1.35
Intronic Alus influence alternative splicing. PLoS Genet (2008) 1.35
Evidence for variation in abundance of antisense transcripts between multicellular animals but no relationship between antisense transcriptionand organismic complexity. Genome Res (2006) 1.35
Hypothesis: RNA editing of microRNA target sites in humans? RNA (2007) 1.30
ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. Proc Natl Acad Sci U S A (2012) 1.25
InvAluable junk: the cellular impact and function of Alu and B2 RNAs. IUBMB Life (2009) 1.24
Letter from the editor: Adenosine-to-inosine RNA editing in Alu repeats in the human genome. EMBO Rep (2005) 1.20
Alu sequences in undifferentiated human embryonic stem cells display high levels of A-to-I RNA editing. PLoS One (2010) 1.15
Evidence for large diversity in the human transcriptome created by Alu RNA editing. Nucleic Acids Res (2009) 1.12
A biochemical landscape of A-to-I RNA editing in the human brain transcriptome. Genome Res (2014) 1.09
Retrotransposons as regulators of gene expression. Science (2016) 1.09
Widespread cleavage of A-to-I hyperediting substrates. RNA (2009) 1.06
Characterization and comparison of human nuclear and cytosolic editomes. Proc Natl Acad Sci U S A (2013) 1.05
A genome-wide map of hyper-edited RNA reveals numerous new sites. Nat Commun (2014) 1.04
Large-scale analysis of structural, sequence and thermodynamic characteristics of A-to-I RNA editing sites in human Alu repeats. BMC Genomics (2010) 1.02
Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR). RNA (2013) 0.98
SINEs point to abundant editing in the human genome. Genome Biol (2005) 0.97
Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa. Br J Cancer (2006) 0.96
Evolution under environmental stress at macro- and microscales. Genome Biol Evol (2011) 0.95
Powerful mutators lurking in the genome. Philos Trans R Soc Lond B Biol Sci (2009) 0.92
Analysis and design of RNA sequencing experiments for identifying RNA editing and other single-nucleotide variants. RNA (2013) 0.92
Altered A-to-I RNA editing in human embryogenesis. PLoS One (2012) 0.90
3'UTR-located ALU elements: donors of potential miRNA target sites and mediators of network miRNA-based regulatory interactions. Evol Bioinform Online (2007) 0.90
Substitutional A-to-I RNA editing. Wiley Interdiscip Rev RNA (2011) 0.88
Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs. J Immunol (2014) 0.88
Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs. Nucleic Acids Res (2008) 0.88
Transcriptome-wide identification of A > I RNA editing sites by inosine specific cleavage. RNA (2012) 0.87
Functional Impact of RNA editing and ADARs on regulation of gene expression: perspectives from deep sequencing studies. Cell Biosci (2014) 0.85
Reciprocal regulation of A-to-I RNA editing and the vertebrate nervous system. Front Neurosci (2013) 0.83
The emerging role of RNA editing in plasticity. J Exp Biol (2015) 0.83
A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicide. Hum Mol Genet (2014) 0.81
Dysregulated A to I RNA editing and non-coding RNAs in neurodegeneration. Front Genet (2013) 0.80
Restricting retrotransposons: a review. Mob DNA (2016) 0.79
A-to-I RNA editing does not change with age in the healthy male rat brain. Biogerontology (2013) 0.79
The conserved protein kinase-A target motif in synapsin of Drosophila is effectively modified by pre-mRNA editing. BMC Neurosci (2006) 0.78
ADAR1 deaminase contributes to scheduled skeletal myogenesis progression via stage-specific functions. Cell Death Differ (2014) 0.77
CAPS1 RNA Editing Promotes Dense Core Vesicle Exocytosis. Cell Rep (2016) 0.75
Massive A-to-I RNA editing is common across the Metazoa and correlates with dsRNA abundance. Genome Biol (2017) 0.75
Widespread occurrence of antisense transcription in the human genome. Nat Biotechnol (2003) 8.54
Human housekeeping genes are compact. Trends Genet (2003) 7.65
Systematic identification of abundant A-to-I editing sites in the human transcriptome. Nat Biotechnol (2004) 7.61
Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite. Nature (2007) 7.42
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature (2012) 7.00
Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing. Science (2009) 6.96
Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient. PLoS Med (2009) 5.50
Evolutionary conservation of sequence and secondary structures in CRISPR repeats. Genome Biol (2007) 5.40
The birth of an alternatively spliced exon: 3' splice-site selection in Alu exons. Science (2003) 5.04
A module of negative feedback regulators defines growth factor signaling. Nat Genet (2007) 4.35
The dynamics and time scale of ongoing genomic erosion in symbiotic bacteria. Science (2009) 4.25
In search of antisense. Trends Biochem Sci (2004) 3.93
Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma. J Clin Oncol (2009) 3.47
A single-base resolution map of an archaeal transcriptome. Genome Res (2009) 3.42
Transcription-mediated gene fusion in the human genome. Genome Res (2005) 3.19
Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells. Cell Stem Cell (2009) 3.09
Human housekeeping genes, revisited. Trends Genet (2013) 2.95
A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration. Nat Cell Biol (2007) 2.85
STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity. N Engl J Med (2009) 2.72
PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop. Mol Cell (2008) 2.66
Comparative transcriptomics of pathogenic and non-pathogenic Listeria species. Mol Syst Biol (2012) 2.64
Self-targeting by CRISPR: gene regulation or autoimmunity? Trends Genet (2010) 2.62
Genomic island variability facilitates Prochlorococcus-virus coexistence. Nature (2011) 2.60
Naturally occurring antisense: transcriptional leakage or real overlap? Genome Res (2005) 2.39
Altered adenosine-to-inosine RNA editing in human cancer. Genome Res (2007) 2.38
Transcriptome-wide discovery of circular RNAs in Archaea. Nucleic Acids Res (2011) 2.33
The phage-host arms race: shaping the evolution of microbes. Bioessays (2011) 2.27
Preferential attachment in the protein network evolution. Phys Rev Lett (2003) 2.23
Validation of two ribosomal RNA removal methods for microbial metatranscriptomics. Nat Methods (2010) 2.21
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation. EMBO J (2004) 2.20
Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus disease. J Infect Dis (2004) 2.03
Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs. Am J Hum Genet (2006) 1.97
Evolutionarily conserved human targets of adenosine to inosine RNA editing. Nucleic Acids Res (2005) 1.96
A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance. Blood (2006) 1.94
Transcriptome-wide mapping of N(6)-methyladenosine by m(6)A-seq based on immunocapturing and massively parallel sequencing. Nat Protoc (2013) 1.91
Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals. Mol Cell (2011) 1.89
MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells. Biochem Biophys Res Commun (2008) 1.85
A survey of genomic traces reveals a common sequencing error, RNA editing, and DNA editing. PLoS Genet (2010) 1.81
A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes. Genome Res (2013) 1.81
Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest. Clin Cancer Res (2005) 1.80
Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs. Cell Cycle (2011) 1.80
Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. Blood (2003) 1.80
RNA-editing-mediated exon evolution. Genome Biol (2007) 1.77
RNA editing level in the mouse is determined by the genomic repeat repertoire. RNA (2006) 1.75
Human and porcine early kidney precursors as a new source for transplantation. Nat Med (2002) 1.73
Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death. Cancer Res (2005) 1.73
Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene. Hum Mol Genet (2004) 1.73
The single-nucleotide resolution transcriptome of Pseudomonas aeruginosa grown in body temperature. PLoS Pathog (2012) 1.72
A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets. J Exp Med (2007) 1.67
Accurate identification of alternatively spliced exons using support vector machine. Bioinformatics (2004) 1.66
MicroRNA expression signatures in intraductal papillary mucinous neoplasm of the pancreas. Surgery (2013) 1.64
Decreased hepcidin mRNA expression in thalassemic mice. Br J Haematol (2004) 1.61
apoB and apobec1, two genes key to lipid metabolism, are transcriptionally regulated by p53. Cell Cycle (2010) 1.59
Isolation and characterization of nontubular sca-1+lin- multipotent stem/progenitor cells from adult mouse kidney. J Am Soc Nephrol (2006) 1.59
Multiple congenital anomalies-hypotonia-seizures syndrome is caused by a mutation in PIGN. J Med Genet (2011) 1.55
The nuclear-envelope protein and transcriptional repressor LAP2beta interacts with HDAC3 at the nuclear periphery, and induces histone H4 deacetylation. J Cell Sci (2005) 1.54
CRISPR targeting reveals a reservoir of common phages associated with the human gut microbiome. Genome Res (2012) 1.52
Homozygous SLC2A9 mutations cause severe renal hypouricemia. J Am Soc Nephrol (2009) 1.52
Clonal expansion and not cell interconversion is the basis for the neuroblast and nonneuronal types of the SK-N-SH neuroblastoma cell line. Cancer Genet Cytogenet (2003) 1.52
Newborn screening for severe T and B cell immunodeficiency in Israel: a pilot study. Isr Med Assoc J (2013) 1.50
Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling. Blood (2003) 1.48
Adenosine-to-inosine RNA editing shapes transcriptome diversity in primates. Proc Natl Acad Sci U S A (2010) 1.47
SKY reveals a high frequency of unbalanced translocations involving chromosome 6 in t(12;21)-positive acute lymphoblastic leukemia. Leuk Res (2007) 1.46
Integration of a palliative and terminal care center into a comprehensive pediatric oncology department. Pediatr Blood Cancer (2008) 1.45
Role of DNA methylation in stable gene repression. J Biol Chem (2007) 1.45
TNF activates a NF-kappaB-regulated cellular program in human CD45RA- regulatory T cells that modulates their suppressive function. J Immunol (2010) 1.43
MDR1 expression identifies human melanoma stem cells. Biochem Biophys Res Commun (2008) 1.41
Evolution of p53 in hypoxia-stressed Spalax mimics human tumor mutation. Proc Natl Acad Sci U S A (2004) 1.41
Searching for evidence of disease and malignant cell contamination in ovarian tissue stored from hematologic cancer patients. Hum Reprod (2008) 1.40
The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain. Clin Cancer Res (2009) 1.39
Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney. Cancer Res (2006) 1.39
The excludon: a new concept in bacterial antisense RNA-mediated gene regulation. Nat Rev Microbiol (2012) 1.37
Gene silencing at the nuclear periphery. FEBS J (2007) 1.36
Intronic Alus influence alternative splicing. PLoS Genet (2008) 1.35
Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis. Genome Biol (2005) 1.31
Downregulation of hepcidin and haemojuvelin expression in the hepatocyte cell-line HepG2 induced by thalassaemic sera. Br J Haematol (2006) 1.31
Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling. J Biol Chem (2004) 1.30
Cell lineage analysis of a mouse tumor. Cancer Res (2008) 1.29
A pivotal role of cyclic AMP-responsive element binding protein in tumor progression. Cancer Res (2004) 1.29
Identification of direct p73 target genes combining DNA microarray and chromatin immunoprecipitation analyses. J Biol Chem (2002) 1.29
Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes. Stem Cells (2008) 1.27
Mammalian conserved ADAR targets comprise only a small fragment of the human editosome. Genome Biol (2014) 1.26
Nanog transforms NIH3T3 cells and targets cell-type restricted genes. Biochem Biophys Res Commun (2006) 1.25
Evolutionary dynamics of large numts in the human genome: rarity of independent insertions and abundance of post-insertion duplications. J Mol Evol (2003) 1.24
Transcriptional modulation induced by ionizing radiation: p53 remains a central player. Mol Oncol (2011) 1.23
Gene expression profiling of sporadic Parkinson's disease substantia nigra pars compacta reveals impairment of ubiquitin-proteasome subunits, SKP1A, aldehyde dehydrogenase, and chaperone HSC-70. Ann N Y Acad Sci (2005) 1.23
mRNA expression of iron regulatory genes in beta-thalassemia intermedia and beta-thalassemia major mouse models. Am J Hematol (2006) 1.22
Transcriptome-wide mapping of 5-methylcytidine RNA modifications in bacteria, archaea, and yeast reveals m5C within archaeal mRNAs. PLoS Genet (2013) 1.22