Published in Proc Natl Acad Sci U S A on January 21, 2005
Evaluation of genetically engineered crops using transcriptomic, proteomic, and metabolomic profiling techniques. Plant Physiol (2011) 1.74
454 pyrosequencing based transcriptome analysis of Zygaena filipendulae with focus on genes involved in biosynthesis of cyanogenic glucosides. BMC Genomics (2009) 1.49
Cassava plants with a depleted cyanogenic glucoside content in leaves and tubers. Distribution of cyanogenic glucosides, their site of synthesis and transport, and blockage of the biosynthesis by RNA interference technology. Plant Physiol (2005) 1.25
Biomimetic enzyme nanocomplexes and their use as antidotes and preventive measures for alcohol intoxication. Nat Nanotechnol (2013) 1.23
Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay. Nucleic Acids Res (2013) 1.16
Biotechnological prospects for engineering insect-resistant plants. Plant Physiol (2008) 1.12
Transcriptome and metabolome profiling of field-grown transgenic barley lack induced differences but show cultivar-specific variances. Proc Natl Acad Sci U S A (2010) 1.11
Metabolic engineering of isoflavonoid biosynthesis in alfalfa. Plant Physiol (2005) 1.06
Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses. Plant Physiol (2008) 1.04
South American leaf blight of the rubber tree (Hevea spp.): new steps in plant domestication using physiological features and molecular markers. Ann Bot (2007) 0.96
Biosynthesis of the cyanogenic glucosides linamarin and lotaustralin in cassava: isolation, biochemical characterization, and expression pattern of CYP71E7, the oxime-metabolizing cytochrome P450 enzyme. Plant Physiol (2010) 0.90
Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses. Plant Physiol (2005) 0.90
Bitterness in almonds. Plant Physiol (2008) 0.88
Metabolomic, transcriptional, hormonal, and signaling cross-talk in superroot2. Mol Plant (2009) 0.88
Identification of defense compounds in Barbarea vulgaris against the herbivore Phyllotreta nemorum by an ecometabolomic approach. Plant Physiol (2009) 0.86
Evidence on the molecular basis of the Ac/ac adaptive cyanogenesis polymorphism in white clover (Trifolium repens L). Genetics (2008) 0.85
The beta-glucosidases responsible for bioactivation of hydroxynitrile glucosides in Lotus japonicus. Plant Physiol (2008) 0.85
Plant metabolic clusters - from genetics to genomics. New Phytol (2016) 0.83
Transfer of the cytochrome P450-dependent dhurrin pathway from Sorghum bicolor into Nicotiana tabacum chloroplasts for light-driven synthesis. J Exp Bot (2016) 0.82
Glucosylation of 4-Hydroxy-2,5-Dimethyl-3(2H)-Furanone, the Key Strawberry Flavor Compound in Strawberry Fruit. Plant Physiol (2016) 0.79
Phenolic compounds in ectomycorrhizal interaction of lignin modified silver birch. BMC Plant Biol (2009) 0.78
Over-expression of a putative poplar glycosyltransferase gene, PtGT1, in tobacco increases lignin content and causes early flowering. J Exp Bot (2012) 0.78
Functionalized anodic aluminum oxide membrane-electrode system for enzyme immobilization. ACS Nano (2014) 0.76
MAPK transgenic circuit to improve plant stress-tolerance? Plant Signal Behav (2014) 0.75
Genetic manipulation of putrescine biosynthesis reprograms the cellular transcriptome and the metabolome. BMC Plant Biol (2016) 0.75
Eugenol Specialty Chemical Production in Transgenic Poplar (Populus tremula × P. alba) Field Trials. Plant Biotechnol J (2017) 0.75
Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A (2001) 132.88
Metabolite profiling for plant functional genomics. Nat Biotechnol (2000) 8.74
Assessment of the sensitivity and specificity of oligonucleotide (50mer) microarrays. Nucleic Acids Res (2000) 6.20
Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2004) 3.41
Optimization of oligonucleotide-based DNA microarrays. Nucleic Acids Res (2002) 3.36
Comparative genomics of rice and Arabidopsis. Analysis of 727 cytochrome P450 genes and pseudogenes from a monocot and a dicot. Plant Physiol (2004) 2.91
The combined effect of drought stress and heat shock on gene expression in tobacco. Plant Physiol (2002) 2.84
Activation of gibberellin biosynthesis and response pathways by low temperature during imbibition of Arabidopsis thaliana seeds. Plant Cell (2004) 2.56
Metabolic channeling in plants. Annu Rev Plant Biol (2004) 2.56
The early stages of duplicate gene evolution. Proc Natl Acad Sci U S A (2003) 2.34
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Intron-exon organization and phylogeny in a large superfamily, the paralogous cytochrome P450 genes of Arabidopsis thaliana. DNA Cell Biol (2000) 2.02
Molecular phenotyping of the pal1 and pal2 mutants of Arabidopsis thaliana reveals far-reaching consequences on phenylpropanoid, amino acid, and carbohydrate metabolism. Plant Cell (2004) 1.89
UGT73C6 and UGT78D1, glycosyltransferases involved in flavonol glycoside biosynthesis in Arabidopsis thaliana. J Biol Chem (2003) 1.78
Regulation of transcript levels of the Arabidopsis cytochrome p450 genes involved in brassinosteroid biosynthesis. Plant Physiol (2002) 1.78
Microarray-based analysis of gene expression in very large gene families: the cytochrome P450 gene superfamily of Arabidopsis thaliana. Gene (2001) 1.67
Resistance to an herbivore through engineered cyanogenic glucoside synthesis. Science (2001) 1.66
On the origin of family 1 plant glycosyltransferases. Phytochemistry (2003) 1.62
The biosynthesis of cyanogenic glucosides in higher plants. Channeling of intermediates in dhurrin biosynthesis by a microsomal system from Sorghum bicolor (linn) Moench. J Biol Chem (1980) 1.60
The Arabidopsis ref2 mutant is defective in the gene encoding CYP83A1 and shows both phenylpropanoid and glucosinolate phenotypes. Plant Cell (2003) 1.58
The involvement of two p450 enzymes, CYP83B1 and CYP83A1, in auxin homeostasis and glucosinolate biosynthesis. Plant Physiol (2001) 1.55
Engineering secondary metabolite production in plants. Curr Opin Biotechnol (2002) 1.53
Plant cytochromes P450: tools for pharmacology, plant protection and phytoremediation. Curr Opin Biotechnol (2003) 1.49
Identification of glucosyltransferase genes involved in sinapate metabolism and lignin synthesis in Arabidopsis. J Biol Chem (2000) 1.49
The activity of Arabidopsis glycosyltransferases toward salicylic acid, 4-hydroxybenzoic acid, and other benzoates. J Biol Chem (2001) 1.47
CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis. Plant Physiol (2003) 1.46
Mutations that reduce sinapoylmalate accumulation in Arabidopsis thaliana define loci with diverse roles in phenylpropanoid metabolism. Genetics (2001) 1.37
Major flavonoids from Arabidopsis thaliana leaves. J Nat Prod (1999) 1.35
Biosynthesis of the Cyanogenic Glucoside Dhurrin in Seedlings of Sorghum bicolor (L.) Moench and Partial Purification of the Enzyme System Involved. Plant Physiol (1989) 1.35
Metabolic engineering of p-hydroxybenzylglucosinolate in Arabidopsis by expression of the cyanogenic CYP79A1 from Sorghum bicolor. Plant J (1999) 1.31
Dhurrin synthesis in sorghum is regulated at the transcriptional level and induced by nitrogen fertilization in older plants. Plant Physiol (2002) 1.14
The biosynthesis of shikimate metabolites. Nat Prod Rep (2003) 1.06
Evidence for phosphorylation requirement for human bilirubin UDP-glucuronosyltransferase (UGT1A1) activity. Biochem Biophys Res Commun (2003) 1.05
The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor. Phytochemistry (2003) 1.01
Transgenic tobacco and Arabidopsis plants expressing the two multifunctional sorghum cytochrome P450 enzymes, CYP79A1 and CYP71E1, are cyanogenic and accumulate metabolites derived from intermediates in Dhurrin biosynthesis. Plant Physiol (2000) 0.99
Isolation of the heme-thiolate enzyme cytochrome P-450TYR, which catalyzes the committed step in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench. Proc Natl Acad Sci U S A (1994) 0.95
Spot shape modelling and data transformations for microarrays. Bioinformatics (2004) 0.93
Metabolic engineering of plants for alkaloid production. Metab Eng (2002) 0.89
Identification of four Arabidopsis genes encoding hydroxycinnamate glucosyltransferases. FEBS Lett (2000) 0.86
Metabolism of tyrosine and tryptophan--new genes for old pathways. Curr Opin Plant Biol (2001) 0.82
A gene expression map of the Arabidopsis root. Science (2003) 9.95
Comparative genomics of rice and Arabidopsis. Analysis of 727 cytochrome P450 genes and pseudogenes from a monocot and a dicot. Plant Physiol (2004) 2.91
Profiling translatomes of discrete cell populations resolves altered cellular priorities during hypoxia in Arabidopsis. Proc Natl Acad Sci U S A (2009) 2.77
Monitoring large-scale changes in transcript abundance in drought- and salt-stressed barley. Plant Mol Biol (2002) 2.75
Cell type-specific expression profiling in plants via cell sorting of protoplasts from fluorescent reporter lines. Nat Methods (2005) 2.62
O-glycosylated cell wall proteins are essential in root hair growth. Science (2011) 2.34
The Oryza bacterial artificial chromosome library resource: construction and analysis of 12 deep-coverage large-insert BAC libraries that represent the 10 genome types of the genus Oryza. Genome Res (2005) 2.23
Camalexin is synthesized from indole-3-acetaldoxime, a key branching point between primary and secondary metabolism in Arabidopsis. Proc Natl Acad Sci U S A (2004) 2.21
Successful herbivore attack due to metabolic diversion of a plant chemical defense. Proc Natl Acad Sci U S A (2004) 2.13
Metabolon formation and metabolic channeling in the biosynthesis of plant natural products. Curr Opin Plant Biol (2005) 1.97
Salt cress. A halophyte and cryophyte Arabidopsis relative model system and its applicability to molecular genetic analyses of growth and development of extremophiles. Plant Physiol (2004) 1.94
Composition and content of glucosinolates in developing Arabidopsis thaliana. Planta (2002) 1.93
CYP71B15 (PAD3) catalyzes the final step in camalexin biosynthesis. Plant Physiol (2006) 1.86
Genome-wide analysis of the Arabidopsis leaf transcriptome reveals interaction of phosphate and sugar metabolism. Plant Physiol (2006) 1.81
NRT/PTR transporters are essential for translocation of glucosinolate defence compounds to seeds. Nature (2012) 1.77
CYP703 is an ancient cytochrome P450 in land plants catalyzing in-chain hydroxylation of lauric acid to provide building blocks for sporopollenin synthesis in pollen. Plant Cell (2007) 1.69
Immunopurification of polyribosomal complexes of Arabidopsis for global analysis of gene expression. Plant Physiol (2005) 1.66
The genome of flax (Linum usitatissimum) assembled de novo from short shotgun sequence reads. Plant J (2012) 1.62
On the origin of family 1 plant glycosyltransferases. Phytochemistry (2003) 1.62
CYP704B1 is a long-chain fatty acid omega-hydroxylase essential for sporopollenin synthesis in pollen of Arabidopsis. Plant Physiol (2009) 1.61
beta-Glucosidases as detonators of plant chemical defense. Phytochemistry (2008) 1.60
Substrate specificity of plant UDP-dependent glycosyltransferases predicted from crystal structures and homology modeling. Phytochemistry (2009) 1.53
454 pyrosequencing based transcriptome analysis of Zygaena filipendulae with focus on genes involved in biosynthesis of cyanogenic glucosides. BMC Genomics (2009) 1.49
Plant cytochromes P450: tools for pharmacology, plant protection and phytoremediation. Curr Opin Biotechnol (2003) 1.49
Cyanogenesis in plants and arthropods. Phytochemistry (2008) 1.49
Comparison of RNA expression profiles based on maize expressed sequence tag frequency analysis and micro-array hybridization. Plant Physiol (2002) 1.48
CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis. Plant Physiol (2003) 1.46
Global characterization of cell-specific gene expression through fluorescence-activated sorting of nuclei. Plant Physiol (2008) 1.44
The daunting process of MIAME. Nature (2006) 1.44
Molecular activities, biosynthesis and evolution of triterpenoid saponins. Phytochemistry (2011) 1.43
Plant P450s as versatile drivers for evolution of species-specific chemical diversity. Philos Trans R Soc Lond B Biol Sci (2013) 1.43
Prevalence of electrocardiographic ST-T changes during acute ischemic stroke in patients without known ischemic heart disease. Int J Cardiol (2007) 1.39
Cytochromes p450. Arabidopsis Book (2011) 1.37
Cyanogenic glucosides and plant-insect interactions. Phytochemistry (2004) 1.34
De novo biosynthesis of vanillin in fission yeast (Schizosaccharomyces pombe) and baker's yeast (Saccharomyces cerevisiae). Appl Environ Microbiol (2009) 1.30
RiceArrayNet: a database for correlating gene expression from transcriptome profiling, and its application to the analysis of coexpressed genes in rice. Plant Physiol (2009) 1.30
Comparison of the contributions of the nuclear and cytoplasmic compartments to global gene expression in human cells. BMC Genomics (2007) 1.30
Meiotically stable natural epialleles of Sadhu, a novel Arabidopsis retroposon. PLoS Genet (2006) 1.28
Cassava plants with a depleted cyanogenic glucoside content in leaves and tubers. Distribution of cyanogenic glucosides, their site of synthesis and transport, and blockage of the biosynthesis by RNA interference technology. Plant Physiol (2005) 1.25
Arabidopsis thaliana RGXT1 and RGXT2 encode Golgi-localized (1,3)-alpha-D-xylosyltransferases involved in the synthesis of pectic rhamnogalacturonan-II. Plant Cell (2006) 1.25
Cyanogenic glycosides: synthesis, physiology, and phenotypic plasticity. Annu Rev Plant Biol (2014) 1.24
Genome structures and halophyte-specific gene expression of the extremophile Thellungiella parvula in comparison with Thellungiella salsuginea (Thellungiella halophila) and Arabidopsis. Plant Physiol (2010) 1.24
Glucosinolate structures in evolution. Phytochemistry (2012) 1.22
Development and evaluation of a high-throughput, low-cost genotyping platform based on oligonucleotide microarrays in rice. Plant Methods (2008) 1.20
Plant systems biology comes of age. Trends Plant Sci (2008) 1.19
AtSAP18, an orthologue of human SAP18, is involved in the regulation of salt stress and mediates transcriptional repression in Arabidopsis. Plant Mol Biol (2006) 1.18
Metabolic engineering in Nicotiana benthamiana reveals key enzyme functions in Arabidopsis indole glucosinolate modification. Plant Cell (2011) 1.17
Plant defense against insect herbivores. Int J Mol Sci (2013) 1.16
RNA-sequencing from single nuclei. Proc Natl Acad Sci U S A (2013) 1.15
Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platform. Metab Eng (2012) 1.15
Integration of biosynthesis and long-distance transport establish organ-specific glucosinolate profiles in vegetative Arabidopsis. Plant Cell (2013) 1.15
Transcript profiling in Vitis riparia during chilling requirement fulfillment reveals coordination of gene expression patterns with optimized bud break. Funct Integr Genomics (2008) 1.15
Methods for transcriptional profiling in plants. Be fruitful and replicate. Plant Physiol (2004) 1.14
Dhurrin synthesis in sorghum is regulated at the transcriptional level and induced by nitrogen fertilization in older plants. Plant Physiol (2002) 1.14
Frequency and significance of troponin T elevation in acute ischemic stroke. Am J Cardiol (2006) 1.13
Plant chemical defense: at what cost? Trends Plant Sci (2013) 1.11
Metabolon formation in dhurrin biosynthesis. Phytochemistry (2007) 1.11
Natural products as starting materials for development of second-generation SERCA inhibitors targeted towards prostate cancer cells. Bioorg Med Chem (2006) 1.10
Convergent evolution in biosynthesis of cyanogenic defence compounds in plants and insects. Nat Commun (2011) 1.10
Conformational changes of the NADPH-dependent cytochrome P450 reductase in the course of electron transfer to cytochromes P450. Biochim Biophys Acta (2010) 1.08
A probable Na+(K+)/H+ exchanger on the chloroplast envelope functions in pH homeostasis and chloroplast development in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2004) 1.08
Plant NADPH-cytochrome P450 oxidoreductases. Phytochemistry (2009) 1.07
The sfr6 mutant of Arabidopsis is defective in transcriptional activation via CBF/DREB1 and DREB2 and shows sensitivity to osmotic stress. Plant J (2003) 1.06
Cloning, functional expression, and characterization of CYP709C1, the first sub-terminal hydroxylase of long chain fatty acid in plants. Induction by chemicals and methyl jasmonate. J Biol Chem (2005) 1.05
Genetic screening identifies cyanogenesis-deficient mutants of Lotus japonicus and reveals enzymatic specificity in hydroxynitrile glucoside metabolism. Plant Cell (2010) 1.05
Pain phenomena and possible mechanisms in patients with painful polyneuropathy. Pain (2003) 1.05
Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses. Plant Physiol (2008) 1.04
Glucosinolate engineering identifies a gamma-glutamyl peptidase. Nat Chem Biol (2009) 1.03
Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants. Proc Natl Acad Sci U S A (2013) 1.03
The construction and use of bacterial DNA microarrays based on an optimized two-stage PCR strategy. BMC Genomics (2003) 1.02
Biosynthesis of the nitrile glucosides rhodiocyanoside A and D and the cyanogenic glucosides lotaustralin and linamarin in Lotus japonicus. Plant Physiol (2004) 1.01
The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor. Phytochemistry (2003) 1.01
Manoyl oxide (13R), the biosynthetic precursor of forskolin, is synthesized in specialized root cork cells in Coleus forskohlii. Plant Physiol (2014) 1.00
Evidence for antisense transcription associated with microRNA target mRNAs in Arabidopsis. PLoS Genet (2009) 1.00
Cytosolic γ-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis. Plant Cell (2011) 0.99
Analysis of PHOTOPERIOD SENSITIVITY5 sheds light on the role of phytochromes in photoperiodic flowering in rice. Plant Physiol (2009) 0.98
The cyanogenic glucoside composition of Zygaena filipendulae (Lepidoptera: Zygaenidae) as effected by feeding on wild-type and transgenic lotus populations with variable cyanogenic glucoside profiles. Insect Biochem Mol Biol (2006) 0.98