Published in J Chem Inf Model on January 25, 2005
An efficient algorithm coupled with synthetic minority over-sampling technique to classify imbalanced PubChem BioAssay data. Anal Chim Acta (2013) 0.88
Linear and nonlinear modeling of antifungal activity of some heterocyclic ring derivatives using multiple linear regression and Bayesian-regularized neural networks. J Mol Model (2005) 0.84
Considerations and recent advances in QSAR models for cytochrome P450-mediated drug metabolism prediction. J Comput Aided Mol Des (2008) 0.79
Genetic neural network modeling of the selective inhibition of the intermediate-conductance Ca2+ -activated K+ channel by some triarylmethanes using topological charge indexes descriptors. J Comput Aided Mol Des (2005) 0.78
QSPR Modeling of Bioconcentration Factors of Nonionic Organic Compounds. Environ Health Insights (2010) 0.75
Curcumin protects rats against acetaminophen-induced hepatorenal damages and shows synergistic activity with N-acetyl cysteine. Eur J Pharmacol (2009) 0.97
Effect of the electronic and physicochemical parameters on the carcinogenesis activity of some sulfa drugs using QSAR analysis based on genetic-MLR and genetic-PLS. Chemosphere (2007) 0.97
Dihydropyridines: evaluation of their current and future pharmacological applications. Drug Discov Today (2009) 0.97
Chemical Composition, Antifungal and Antibiofilm Activities of the Essential Oil of Mentha piperita L. ISRN Pharm (2012) 0.97
Direct Effect of Two Naphthalene-Sulfonyl-Indole Compounds on Toxoplasma gondii Tachyzoite. J Parasitol Res (2013) 0.94
Immunomodulatory activities of various medicinal plant extracts: effects on human lymphocytes apoptosis. Immunol Invest (2009) 0.91
Design and synthesis of methyl 2-methyl-7,7-dihalo-5-phenyl-2-azabicyclo[4.1.0]hept-3-ene-4-carboxylates with calcium channel antagonist activity. Bioorg Med Chem (2004) 0.90
Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress. Biochimie (2011) 0.89
Synthesis and antiproliferative activity evaluation of imidazole-based indeno[1,2-b]quinoline-9,11-dione derivatives. Arch Pharm Res (2013) 0.89
Quantitative structure-activity relationship study of recently synthesized 1,4-dihydropyridine calcium channel antagonists. Application of the Hansch analysis method. Arch Pharm (Weinheim) (2002) 0.87
Synthesis, QSAR and calcium channel antagonist activity of new 1,4-dihydropyridine derivatives containing 1-methyl-4,5-dichloroimidazolyl substituents. Arch Pharm (Weinheim) (2007) 0.87
Dihydropyridine derivatives to overcome atypical multidrug resistance: design, synthesis, QSAR studies, and evaluation of their cytotoxic and pharmacological activities. Chem Biol Drug Des (2007) 0.87
Application of ab initio theory to QSAR study of 1,4-dihydropyridine-based calcium channel blockers using GA-MLR and PC-GA-ANN procedures. J Comput Chem (2004) 0.87
Lipophilic 4-imidazoly-1,4-dihydropyridines: synthesis, calcium channel antagonist activity and protection against pentylenetetrazole-induced seizure. Farmaco (2004) 0.86
Synthesis and antitubercular activity of novel 4-substituted imidazolyl-2,6-dimethyl-N3,N5-bisaryl-1,4-dihydropyridine-3,5-dicarboxamides. Eur J Med Chem (2009) 0.86
Biological activity and chemical constituents of red and brown algae from the persian gulf. Iran J Pharm Res (2013) 0.85
QSAR study of 4-aryl-4H-chromenes as a new series of apoptosis inducers using different chemometric tools. Chem Biol Drug Des (2012) 0.85
Design and synthesis of 2-phenoxynicotinic acid hydrazides as anti-inflammatory and analgesic agents. Arch Pharm (Weinheim) (2010) 0.83
Dietary phenolic acids and derivatives. Evaluation of the antioxidant activity of sinapic acid and its alkyl esters. J Agric Food Chem (2010) 0.83
Genetic algorithm applied to the selection of factors in principal component-artificial neural networks: application to QSAR study of calcium channel antagonist activity of 1,4-dihydropyridines (nifedipine analogous). J Chem Inf Comput Sci (2003) 0.83
QSAR studies on the anesthetic action of some polyhalogenated ethers. Chem Biol Drug Des (2007) 0.82
2H-chromene derivatives bearing thiazolidine-2,4-dione, rhodanine or hydantoin moieties as potential anticancer agents. Eur J Med Chem (2012) 0.81
Fragment-based Binding Efficiency Indices in Bioactive Molecular Design: A Computational Approach to BACE-1 Inhibitors. Iran J Pharm Res (2013) 0.81
Reversal of multidrug resistance in cancer cells by novel asymmetrical 1,4-dihydropyridines. Arch Pharm Res (2013) 0.81
Protective effect of bilberry extract as a pretreatment on induced oral mucositis in hamsters. Oral Surg Oral Med Oral Pathol Oral Radiol (2013) 0.81
Response surface methodology in docking study of small molecule BACE-1 inhibitors. J Mol Model (2012) 0.80
Design and synthesis of new symmetrical derivatives of dihydropyridine containing a pyridyl group on the 3, 5-positions and evaluation of their cytotoxic and multidrug resistance reversal activity. J Pharm Pharmacol (2008) 0.80
Modeling calcium channel antagonistic activity of dihydropyridine derivatives using QTMS indices analyzed by GA-PLS and PC-GA-PLS. J Mol Graph Model (2007) 0.80
Exploring QSAR for substituted 2-sulfonyl-phenyl-indol derivatives as potent and selective COX-2 inhibitors using different chemometrics tools. Chem Biol Drug Des (2008) 0.80
Design and synthesis of novel 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridines as small molecule BACE-1 inhibitors. Bioorg Med Chem (2013) 0.79
Linear and nonlinear quantitative structure-property relationship models for solubility of some anthraquinone, anthrone and xanthone derivatives in supercritical carbon dioxide. Anal Chim Acta (2008) 0.78
Microwave-assisted solvent-free synthesis of Bis(dihydropyrimidinone)benzenes and evaluation of their cytotoxic activity. Chem Biol Drug Des (2010) 0.77
Spectroscopic characterization of human immunodeficiency virus type-1-infected plasma by principal component analysis and soft independent modeling of class analogy of visible and near-infrared spectra. Mol Med Rep (2011) 0.77
Cytotoxic, antioxidant and antimicrobial effects of nine species of woundwort (Stachys) plants. Pharm Biol (2013) 0.77
Computer-aided design of novel antibacterial 3-hydroxypyridine-4-ones: application of QSAR methods based on the MOLMAP approach. J Comput Aided Mol Des (2012) 0.77
Carthamus, Salvia and Stachys species protect neuronal cells against oxidative stress-induced apoptosis. Pharm Biol (2014) 0.77
Synthesis and biological evaluation of some new 1,4-dihydropyridines containing different ester substitute and diethyl carbamoyl group as anti-tubercular agents. Bioorg Med Chem (2009) 0.77
QSAR study of Phenoxypyrimidine Derivatives as Potent Inhibitors of p38 Kinase using different chemometric tools. Chem Biol Drug Des (2007) 0.76
Accurate prediction of the blood-brain partitioning of a large set of solutes using ab initio calculations and genetic neural network modeling. J Comput Chem (2006) 0.76
Polyoxygenated cinnamoylcoumarins as conformationally constrained analogs of cytotoxic diarylpentanoids: synthesis and biological activity. Eur J Med Chem (2013) 0.76
Smell identification function in children with attention deficit hyperactivity disorder. Psychiatry Investig (2012) 0.75
Comparative amino acid decomposition analysis of potent type I p38α inhibitors. Daru (2013) 0.75
Synthesis and cytotoxic activity of novel poly-substituted imidazo[2,1-c][1,2,4]triazin-6-amines. Mol Divers (2015) 0.75
Cytotoxic activity assessment, QSAR and docking study of novel bis-carboxamide derivatives of 4-pyrones synthesized by Ugi four-component reaction. Eur J Med Chem (2013) 0.75
A segmented principal component analysis--regression approach to QSAR study of peptides. J Theor Biol (2012) 0.75
N-(2-(Piperazin-1-yl)phenyl)arylamide Derivatives as β-Secretase (BACE1) Inhibitors: Simple Synthesis by Ugi Four-Component Reaction and Biological Evaluation. Arch Pharm (Weinheim) (2015) 0.75
Design, synthesis and biological evaluation of novel anti-cytokine 1,2,4-triazine derivatives. Bioorg Med Chem (2013) 0.75
Synthesis and calcium channel antagonist activity of new 1,4-dihydropyridine derivatives containing lipophilic 4-imidazolyl substituents. Arzneimittelforschung (2004) 0.75
Multivariate image analysis-thin layer chromatography (MIA-TLC) for simultaneous determination of co-eluting components. Analyst (2010) 0.75
D-penicillamine, a potent melanogenesis inhibitor, lacks any depigmenting effect on black guinea pig skin: the first randomized, evaluator-blinded, vehicle-controlled, in vivo study. Acta Dermatovenerol Alp Pannonica Adriat (2011) 0.75
A mechanistic QSAR study on the leishmanicidal activity of some 5-substituted-1,3,4-thiadiazole derivatives. Chem Biol Drug Des (2007) 0.75
Neuroprotective and Antioxidant Activities of 4-Methylcoumarins: Development of Structure-Activity Relationships. Biol Pharm Bull (2016) 0.75
A study of the photo-degradation kinetics of nifedipine by multivariate curve resolution analysis. J Pharm Biomed Anal (2003) 0.75
Net analyte signal-based simultaneous determination of antazoline and naphazoline using wavelength region selection by experimental design-neural networks. Talanta (2005) 0.75
Iron chelation afforded cardioprotection against H2O2-induced H9C2 cell injury: application of novel 3-hydroxy pyridine-4-one derivatives. Int J Cardiol (2012) 0.75
Phenylimino-2H-chromen-3-carboxamide derivatives as novel small molecule inhibitors of β-secretase (BACE1). Bioorg Med Chem (2013) 0.75
Dihydropyridines and multidrug resistance: previous attempts, present state, and future trends. Chem Biol Drug Des (2010) 0.75
Application of a self-modeling curve resolution method for studying the photodegradation kinetics of nitrendipine and felodipine. J Pharm Biomed Anal (2007) 0.75
Application of MOLMAP approach for QSAR modeling of various biological activities using substituent electronic descriptors. J Comput Chem (2009) 0.75
Chemical classification of the essential oils of the Iranian Salvia species in comparison with their botanical taxonomy. Chem Biodivers (2012) 0.75
HPLC method for analysis of a new 1,4-dihydropyridine: application to pharmacokinetic study in rabbit. J Pharm Biomed Anal (2005) 0.75
Antioxidant activity and total phenolic content of 24 Lamiaceae species growing in Iran. Nat Prod Commun (2010) 0.75
Partial least squares-based multivariate spectral calibration method for simultaneous determination of beta-carboline derivatives in Peganum harmala seed extracts. Anal Chim Acta (2006) 0.75
Comparative QSAR studies on toxicity of phenol derivatives using quantum topological molecular similarity indices. Chem Biol Drug Des (2010) 0.75