Published in Chem Biol Drug Des on January 30, 2012
Probing the origins of aromatase inhibitory activity of disubstituted coumarins via QSAR and molecular docking. EXCLI J (2014) 0.77
Comparative QSAR Analysis of 3,5-bis (Arylidene)-4-Piperidone Derivatives: the Development of Predictive Cytotoxicity Models. Iran J Pharm Res (2016) 0.75
In Silico Screening of IL-1β Production Inhibitors Using Chemometric Tools. Iran J Pharm Res (2017) 0.75
Thiazolyl N-benzyl-substituted acetamide derivatives: synthesis, Src kinase inhibitory and anticancer activities. Eur J Med Chem (2011) 1.26
Nitroimidazolyl-1,3,4-thiadiazole-based anti-leishmanial agents: synthesis and in vitro biological evaluation. Eur J Med Chem (2008) 1.25
Structural features of new quinolones and relationship to antibacterial activity against Gram-positive bacteria. Mini Rev Med Chem (2006) 1.19
2-Hydroxyphenacyl azoles and related azolium derivatives as antifungal agents. Bioorg Med Chem Lett (2007) 1.17
Synthesis and biological evaluation of 2-phenylthiazole-4-carboxamide derivatives as anticancer agents. Eur J Med Chem (2010) 1.11
Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family. Biomed Pharmacother (2011) 1.04
Antiproliferative activity of flavonoids: influence of the sequential methoxylation state of the flavonoid structure. Phytother Res (2011) 0.99
Curcumin protects rats against acetaminophen-induced hepatorenal damages and shows synergistic activity with N-acetyl cysteine. Eur J Pharmacol (2009) 0.97
Effect of the electronic and physicochemical parameters on the carcinogenesis activity of some sulfa drugs using QSAR analysis based on genetic-MLR and genetic-PLS. Chemosphere (2007) 0.97
Dihydropyridines: evaluation of their current and future pharmacological applications. Drug Discov Today (2009) 0.97
Chemical Composition, Antifungal and Antibiofilm Activities of the Essential Oil of Mentha piperita L. ISRN Pharm (2012) 0.97
Synthesis and In vitro cytotoxic activity evaluation of (E)-16-(substituted benzylidene) derivatives of dehydroepiandrosterone. Daru (2013) 0.97
Anti-Helicobacter pylori activity and Structure-Activity Relationship study of 2-Alkylthio-5-(nitroaryl)-1,3,4-thiadiazole Derivatives. Iran J Pharm Res (2013) 0.96
Asymmetrical 2,6-bis(benzylidene)cyclohexanones: Synthesis, cytotoxic activity and QSAR study. Eur J Med Chem (2012) 0.95
Synthesis and cytotoxic properties of novel (E)-3-benzylidene-7-methoxychroman-4-one derivatives. Daru (2013) 0.95
Direct Effect of Two Naphthalene-Sulfonyl-Indole Compounds on Toxoplasma gondii Tachyzoite. J Parasitol Res (2013) 0.94
Synthesis and biological evaluation of 3-(trimethoxyphenyl)-2(3H)-thiazole thiones as combretastatin analogs. Eur J Med Chem (2013) 0.94
Design, synthesis and anticholinesterase activity of a novel series of 1-benzyl-4-((6-alkoxy-3-oxobenzofuran-2(3H)-ylidene) methyl) pyridinium derivatives. Bioorg Med Chem (2010) 0.93
Immunomodulatory activities of various medicinal plant extracts: effects on human lymphocytes apoptosis. Immunol Invest (2009) 0.91
Design and synthesis of methyl 2-methyl-7,7-dihalo-5-phenyl-2-azabicyclo[4.1.0]hept-3-ene-4-carboxylates with calcium channel antagonist activity. Bioorg Med Chem (2004) 0.90
Design of conformationally constrained azole antifungals: efficient synthesis and antifungal activity of trans-3-imidazolylflavanones. Chem Biol Drug Des (2009) 0.90
Synthesis and antileishmanial activity of novel 5-(5-nitrofuran-2-y1)-1,3,4-thiadiazoles with piperazinyl-linked benzamidine substituents. Eur J Med Chem (2011) 0.89
Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress. Biochimie (2011) 0.89
Synthesis and antiproliferative activity evaluation of imidazole-based indeno[1,2-b]quinoline-9,11-dione derivatives. Arch Pharm Res (2013) 0.89
A new strategy based on pharmacophore-based virtual screening in adenosine deaminase inhibitors detection and in-vitro study. Daru (2012) 0.88
N,N-Dimethyl-propane-1,2-diaminium bis-(6-carb-oxy-pyridine-2-carboxyl-ate) monohydrate. Acta Crystallogr Sect E Struct Rep Online (2011) 0.88
Development and validation of a rapid HPLC method for simultaneous determination of tramadol, and its two main metabolites in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 0.87
Quantitative structure-activity relationship study of recently synthesized 1,4-dihydropyridine calcium channel antagonists. Application of the Hansch analysis method. Arch Pharm (Weinheim) (2002) 0.87
Dihydropyridine derivatives to overcome atypical multidrug resistance: design, synthesis, QSAR studies, and evaluation of their cytotoxic and pharmacological activities. Chem Biol Drug Des (2007) 0.87
Synthesis, QSAR and calcium channel antagonist activity of new 1,4-dihydropyridine derivatives containing 1-methyl-4,5-dichloroimidazolyl substituents. Arch Pharm (Weinheim) (2007) 0.87
5,6-Dimethoxybenzofuran-3-one derivatives: a novel series of dual Acetylcholinesterase/Butyrylcholinesterase inhibitors bearing benzyl pyridinium moiety. Daru (2013) 0.87
Cytotoxic activity evaluation and QSAR study of chromene-based chalcones. Arch Pharm Res (2012) 0.87
Application of ab initio theory to QSAR study of 1,4-dihydropyridine-based calcium channel blockers using GA-MLR and PC-GA-ANN procedures. J Comput Chem (2004) 0.87
Lipophilic 4-imidazoly-1,4-dihydropyridines: synthesis, calcium channel antagonist activity and protection against pentylenetetrazole-induced seizure. Farmaco (2004) 0.86
2,3-Diamino-pyridinium 6-carb-oxy-pyridine-2-carboxyl-ate. Acta Crystallogr Sect E Struct Rep Online (2011) 0.86
Medicinal plants in the treatment of Helicobacter pylori infections. Pharm Biol (2014) 0.86
Synthesis, QSAR and calcium channel modulator activity of new hexahydroquinoline derivatives containing nitroimidazole. Chem Biol Drug Des (2007) 0.86
Synthesis and antitubercular activity of novel 4-substituted imidazolyl-2,6-dimethyl-N3,N5-bisaryl-1,4-dihydropyridine-3,5-dicarboxamides. Eur J Med Chem (2009) 0.86
Synthesis and in vitro anti-leishmanial activity of 1-[5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-yl]- and 1-[5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl]-4-aroylpiperazines. Bioorg Med Chem (2008) 0.85
Toward an optimal procedure for PC-ANN model building: prediction of the carcinogenic activity of a large set of drugs. J Chem Inf Model (2005) 0.85
Functionalized N(2-oxyiminoethyl) piperazinyl quinolones as new cytotoxic agents. J Pharm Pharm Sci (2007) 0.85
Solid-phase extraction and simultaneous determination of trace amounts of sulphonated and azo sulphonated dyes using microemulsion-modified-zeolite and multivariate calibration. Talanta (2007) 0.85
5-Nitroimidazole-based 1,3,4-thiadiazoles: heterocyclic analogs of metronidazole as anti-Helicobacter pylori agents. Arch Pharm (Weinheim) (2010) 0.85
Biological activity and chemical constituents of red and brown algae from the persian gulf. Iran J Pharm Res (2013) 0.85
Synthesis and anti-leishmanial activity of 5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-amines containing N-[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl] moieties. Eur J Med Chem (2012) 0.85
Simultaneous spectrophotometric determination of carbamazepine and phenytoin in serum by PLS regression and comparison with HPLC. Talanta (2005) 0.84
Study of the anti-inflammatory and analgesic effects of novel rigid benzofuran-3, 4-dihydroxy chalcone by formalin, hot-plate and carrageenan tests in mice. Pak J Pharm Sci (2009) 0.84
Synthesis and In-vitro Antibacterial Activities of Acetylanthracene and Acetylphenanthrene Derivatives of Some Fluoroquinolones. Iran J Pharm Res (2011) 0.84
Anti-Helicobacter pylori activity of the methanolic extract of Geum iranicum and its main compounds. Z Naturforsch C (2012) 0.84
Synthesis, analgesic and anti-inflammatory activity of 4-(2-phenoxyphenyl)semicarbazones. Arch Pharm (Weinheim) (2007) 0.84
Synthesis and in-vitro cytotoxicity of poly-functionalized 4-(2-arylthiazol-4-yl)-4H-chromenes. Arch Pharm (Weinheim) (2010) 0.84
4-Aryl-4H-naphthopyrans derivatives: one-pot synthesis, evaluation of Src kinase inhibitory and anti-proliferative activities. Daru (2012) 0.84
Synthesis and in vitro anti-Helicobacter pylori activity of N-[5-(5-nitro-2-heteroaryl)-1,3,4-thiadiazol-2-yl]thiomorpholines and related compounds. Eur J Med Chem (2007) 0.83
Synthesis and antibacterial activity of quinolone-based compounds containing a coumarin moiety. Arch Pharm (Weinheim) (2008) 0.83
Design and synthesis of 2-phenoxynicotinic acid hydrazides as anti-inflammatory and analgesic agents. Arch Pharm (Weinheim) (2010) 0.83
Comparison of the effect of non-antifungal and antifungal agents on Candida isolates from the gastrointestinal tract. Arch Iran Med (2012) 0.83
Novel coumarin derivatives bearing N-benzyl pyridinium moiety: potent and dual binding site acetylcholinesterase inhibitors. Bioorg Med Chem (2012) 0.83
Dietary phenolic acids and derivatives. Evaluation of the antioxidant activity of sinapic acid and its alkyl esters. J Agric Food Chem (2010) 0.83
Genetic algorithm applied to the selection of factors in principal component-artificial neural networks: application to QSAR study of calcium channel antagonist activity of 1,4-dihydropyridines (nifedipine analogous). J Chem Inf Comput Sci (2003) 0.83
Synthesis and antibacterial activity of nitroaryl thiadiazole-gatifloxacin hybrids. Eur J Med Chem (2008) 0.82
QSAR studies on the anesthetic action of some polyhalogenated ethers. Chem Biol Drug Des (2007) 0.82
Affinity of two novel five-coordinated anticancer Pt(II) complexes to human and bovine serum albumins: a spectroscopic approach. Inorg Chem (2012) 0.82
Discrimination of edible oils and fats by combination of multivariate pattern recognition and FT-IR spectroscopy: a comparative study between different modeling methods. Spectrochim Acta A Mol Biomol Spectrosc (2012) 0.82
New 5-(nitroheteroaryl)-1,3,4-thiadiazols containing acyclic amines at C-2: synthesis and SAR study for their antileishmanial activity. J Enzyme Inhib Med Chem (2012) 0.82
4-Aryl-4H-chromene-3-carbonitrile derivatives: evaluation of Src kinase inhibitory and anticancer activities. Med Chem (2011) 0.81
Synthesis and antidiabetic evaluation of benzenesulfonamide derivatives. Iran J Pharm Res (2013) 0.81
Reversal of multidrug resistance in cancer cells by novel asymmetrical 1,4-dihydropyridines. Arch Pharm Res (2013) 0.81
Fragment-based Binding Efficiency Indices in Bioactive Molecular Design: A Computational Approach to BACE-1 Inhibitors. Iran J Pharm Res (2013) 0.81
Selective leishmanicidal effect of 1,3,4-thiadiazole derivatives and possible mechanism of action against Leishmania species. Exp Parasitol (2008) 0.81
Synthesis, study of 3D structures, and pharmacological activities of lipophilic nitroimidazolyl-1,4-dihydropyridines as calcium channel antagonist. Bioorg Med Chem (2006) 0.81
Protective effect of bilberry extract as a pretreatment on induced oral mucositis in hamsters. Oral Surg Oral Med Oral Pathol Oral Radiol (2013) 0.81
Enantioselective determination of tramadol and its main phase I metabolites in human plasma by high-performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 0.81
Simultaneous spectrophotometric determination of paracetamol and para-aminophenol in pharmaceutical dosage forms using two novel multivariate standard addition methods based on net analyte signal and rank annihilation factor analysis. Drug Test Anal (2011) 0.81
Synthesis and in vitro antimicrobial evaluation of 5-(1-methyl-5-nitro-2-imidazolyl)-4H-1,2,4-triazoles. Arch Pharm (Weinheim) (2002) 0.81
2H-chromene derivatives bearing thiazolidine-2,4-dione, rhodanine or hydantoin moieties as potential anticancer agents. Eur J Med Chem (2012) 0.81
Induction of apoptosis through tubulin inhibition in human cancer cells by new chromene-based chalcones. Pharm Biol (2012) 0.81
In vitro immunobiological studies of novel 5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazoles with piperazinyl-linked benzamidine substituents against Leishmania major. Iran J Allergy Asthma Immunol (2013) 0.80
Response surface methodology in docking study of small molecule BACE-1 inhibitors. J Mol Model (2012) 0.80
Synthesis and in-vitro antibacterial activity of 5-substituted 1-methyl-4-nitro-1H-imidazoles. Arch Pharm (Weinheim) (2008) 0.80
Halogenated flavanones as potential apoptosis-inducing agents: synthesis and biological activity evaluation. Eur J Med Chem (2012) 0.80
Modeling calcium channel antagonistic activity of dihydropyridine derivatives using QTMS indices analyzed by GA-PLS and PC-GA-PLS. J Mol Graph Model (2007) 0.80
Design and synthesis of new symmetrical derivatives of dihydropyridine containing a pyridyl group on the 3, 5-positions and evaluation of their cytotoxic and multidrug resistance reversal activity. J Pharm Pharmacol (2008) 0.80
Synthesis, evaluation of pharmacological activities and quantitative structure-activity relationship studies of a novel group of bis(4-nitroaryl-1,4-dihyropyridine). Chem Biol Drug Des (2009) 0.80
Synthesis and free radical scavenging activity of coumarin derivatives containing a 2-methylbenzothiazoline motif. Arch Pharm (Weinheim) (2011) 0.80
Synthesis and antibacterial activity of new N-[2-(thiophen-3-yl)ethyl] piperazinyl quinolones. Chem Pharm Bull (Tokyo) (2007) 0.80
Exploring QSAR for substituted 2-sulfonyl-phenyl-indol derivatives as potent and selective COX-2 inhibitors using different chemometrics tools. Chem Biol Drug Des (2008) 0.80