Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Curcumin protects rats against acetaminophen-induced hepatorenal damages and shows synergistic activity with N-acetyl cysteine.
|
Eur J Pharmacol
|
2009
|
0.97
|
2
|
Effect of the electronic and physicochemical parameters on the carcinogenesis activity of some sulfa drugs using QSAR analysis based on genetic-MLR and genetic-PLS.
|
Chemosphere
|
2007
|
0.97
|
3
|
Dihydropyridines: evaluation of their current and future pharmacological applications.
|
Drug Discov Today
|
2009
|
0.97
|
4
|
Chemical Composition, Antifungal and Antibiofilm Activities of the Essential Oil of Mentha piperita L.
|
ISRN Pharm
|
2012
|
0.97
|
5
|
Direct Effect of Two Naphthalene-Sulfonyl-Indole Compounds on Toxoplasma gondii Tachyzoite.
|
J Parasitol Res
|
2013
|
0.94
|
6
|
Immunomodulatory activities of various medicinal plant extracts: effects on human lymphocytes apoptosis.
|
Immunol Invest
|
2009
|
0.91
|
7
|
Design and synthesis of methyl 2-methyl-7,7-dihalo-5-phenyl-2-azabicyclo[4.1.0]hept-3-ene-4-carboxylates with calcium channel antagonist activity.
|
Bioorg Med Chem
|
2004
|
0.90
|
8
|
Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress.
|
Biochimie
|
2011
|
0.89
|
9
|
Synthesis and antiproliferative activity evaluation of imidazole-based indeno[1,2-b]quinoline-9,11-dione derivatives.
|
Arch Pharm Res
|
2013
|
0.89
|
10
|
Dihydropyridine derivatives to overcome atypical multidrug resistance: design, synthesis, QSAR studies, and evaluation of their cytotoxic and pharmacological activities.
|
Chem Biol Drug Des
|
2007
|
0.87
|
11
|
Quantitative structure-activity relationship study of recently synthesized 1,4-dihydropyridine calcium channel antagonists. Application of the Hansch analysis method.
|
Arch Pharm (Weinheim)
|
2002
|
0.87
|
12
|
Synthesis, QSAR and calcium channel antagonist activity of new 1,4-dihydropyridine derivatives containing 1-methyl-4,5-dichloroimidazolyl substituents.
|
Arch Pharm (Weinheim)
|
2007
|
0.87
|
13
|
Application of ab initio theory to QSAR study of 1,4-dihydropyridine-based calcium channel blockers using GA-MLR and PC-GA-ANN procedures.
|
J Comput Chem
|
2004
|
0.87
|
14
|
Lipophilic 4-imidazoly-1,4-dihydropyridines: synthesis, calcium channel antagonist activity and protection against pentylenetetrazole-induced seizure.
|
Farmaco
|
2004
|
0.86
|
15
|
Synthesis and antitubercular activity of novel 4-substituted imidazolyl-2,6-dimethyl-N3,N5-bisaryl-1,4-dihydropyridine-3,5-dicarboxamides.
|
Eur J Med Chem
|
2009
|
0.86
|
16
|
Toward an optimal procedure for PC-ANN model building: prediction of the carcinogenic activity of a large set of drugs.
|
J Chem Inf Model
|
2005
|
0.85
|
17
|
Biological activity and chemical constituents of red and brown algae from the persian gulf.
|
Iran J Pharm Res
|
2013
|
0.85
|
18
|
QSAR study of 4-aryl-4H-chromenes as a new series of apoptosis inducers using different chemometric tools.
|
Chem Biol Drug Des
|
2012
|
0.85
|
19
|
Design and synthesis of 2-phenoxynicotinic acid hydrazides as anti-inflammatory and analgesic agents.
|
Arch Pharm (Weinheim)
|
2010
|
0.83
|
20
|
Dietary phenolic acids and derivatives. Evaluation of the antioxidant activity of sinapic acid and its alkyl esters.
|
J Agric Food Chem
|
2010
|
0.83
|
21
|
Genetic algorithm applied to the selection of factors in principal component-artificial neural networks: application to QSAR study of calcium channel antagonist activity of 1,4-dihydropyridines (nifedipine analogous).
|
J Chem Inf Comput Sci
|
2003
|
0.83
|
22
|
QSAR studies on the anesthetic action of some polyhalogenated ethers.
|
Chem Biol Drug Des
|
2007
|
0.82
|
23
|
Protective effect of bilberry extract as a pretreatment on induced oral mucositis in hamsters.
|
Oral Surg Oral Med Oral Pathol Oral Radiol
|
2013
|
0.81
|
24
|
Fragment-based Binding Efficiency Indices in Bioactive Molecular Design: A Computational Approach to BACE-1 Inhibitors.
|
Iran J Pharm Res
|
2013
|
0.81
|
25
|
Reversal of multidrug resistance in cancer cells by novel asymmetrical 1,4-dihydropyridines.
|
Arch Pharm Res
|
2013
|
0.81
|
26
|
2H-chromene derivatives bearing thiazolidine-2,4-dione, rhodanine or hydantoin moieties as potential anticancer agents.
|
Eur J Med Chem
|
2012
|
0.81
|
27
|
Design and synthesis of new symmetrical derivatives of dihydropyridine containing a pyridyl group on the 3, 5-positions and evaluation of their cytotoxic and multidrug resistance reversal activity.
|
J Pharm Pharmacol
|
2008
|
0.80
|
28
|
Modeling calcium channel antagonistic activity of dihydropyridine derivatives using QTMS indices analyzed by GA-PLS and PC-GA-PLS.
|
J Mol Graph Model
|
2007
|
0.80
|
29
|
Response surface methodology in docking study of small molecule BACE-1 inhibitors.
|
J Mol Model
|
2012
|
0.80
|
30
|
Exploring QSAR for substituted 2-sulfonyl-phenyl-indol derivatives as potent and selective COX-2 inhibitors using different chemometrics tools.
|
Chem Biol Drug Des
|
2008
|
0.80
|
31
|
Design and synthesis of novel 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridines as small molecule BACE-1 inhibitors.
|
Bioorg Med Chem
|
2013
|
0.79
|
32
|
Linear and nonlinear quantitative structure-property relationship models for solubility of some anthraquinone, anthrone and xanthone derivatives in supercritical carbon dioxide.
|
Anal Chim Acta
|
2008
|
0.78
|
33
|
Cytotoxic, antioxidant and antimicrobial effects of nine species of woundwort (Stachys) plants.
|
Pharm Biol
|
2013
|
0.77
|
34
|
Spectroscopic characterization of human immunodeficiency virus type-1-infected plasma by principal component analysis and soft independent modeling of class analogy of visible and near-infrared spectra.
|
Mol Med Rep
|
2011
|
0.77
|
35
|
Carthamus, Salvia and Stachys species protect neuronal cells against oxidative stress-induced apoptosis.
|
Pharm Biol
|
2014
|
0.77
|
36
|
Synthesis and biological evaluation of some new 1,4-dihydropyridines containing different ester substitute and diethyl carbamoyl group as anti-tubercular agents.
|
Bioorg Med Chem
|
2009
|
0.77
|
37
|
Microwave-assisted solvent-free synthesis of Bis(dihydropyrimidinone)benzenes and evaluation of their cytotoxic activity.
|
Chem Biol Drug Des
|
2010
|
0.77
|
38
|
Computer-aided design of novel antibacterial 3-hydroxypyridine-4-ones: application of QSAR methods based on the MOLMAP approach.
|
J Comput Aided Mol Des
|
2012
|
0.77
|
39
|
QSAR study of Phenoxypyrimidine Derivatives as Potent Inhibitors of p38 Kinase using different chemometric tools.
|
Chem Biol Drug Des
|
2007
|
0.76
|
40
|
Accurate prediction of the blood-brain partitioning of a large set of solutes using ab initio calculations and genetic neural network modeling.
|
J Comput Chem
|
2006
|
0.76
|
41
|
Polyoxygenated cinnamoylcoumarins as conformationally constrained analogs of cytotoxic diarylpentanoids: synthesis and biological activity.
|
Eur J Med Chem
|
2013
|
0.76
|
42
|
Comparative amino acid decomposition analysis of potent type I p38α inhibitors.
|
Daru
|
2013
|
0.75
|
43
|
Smell identification function in children with attention deficit hyperactivity disorder.
|
Psychiatry Investig
|
2012
|
0.75
|
44
|
D-penicillamine, a potent melanogenesis inhibitor, lacks any depigmenting effect on black guinea pig skin: the first randomized, evaluator-blinded, vehicle-controlled, in vivo study.
|
Acta Dermatovenerol Alp Pannonica Adriat
|
2011
|
0.75
|
45
|
Iron chelation afforded cardioprotection against H2O2-induced H9C2 cell injury: application of novel 3-hydroxy pyridine-4-one derivatives.
|
Int J Cardiol
|
2012
|
0.75
|
46
|
Phenylimino-2H-chromen-3-carboxamide derivatives as novel small molecule inhibitors of β-secretase (BACE1).
|
Bioorg Med Chem
|
2013
|
0.75
|
47
|
Neuroprotective and Antioxidant Activities of 4-Methylcoumarins: Development of Structure-Activity Relationships.
|
Biol Pharm Bull
|
2016
|
0.75
|
48
|
Net analyte signal-based simultaneous determination of antazoline and naphazoline using wavelength region selection by experimental design-neural networks.
|
Talanta
|
2005
|
0.75
|
49
|
Synthesis and calcium channel antagonist activity of new 1,4-dihydropyridine derivatives containing lipophilic 4-imidazolyl substituents.
|
Arzneimittelforschung
|
2004
|
0.75
|
50
|
Multivariate image analysis-thin layer chromatography (MIA-TLC) for simultaneous determination of co-eluting components.
|
Analyst
|
2010
|
0.75
|
51
|
A study of the photo-degradation kinetics of nifedipine by multivariate curve resolution analysis.
|
J Pharm Biomed Anal
|
2003
|
0.75
|
52
|
Application of a self-modeling curve resolution method for studying the photodegradation kinetics of nitrendipine and felodipine.
|
J Pharm Biomed Anal
|
2007
|
0.75
|
53
|
Application of MOLMAP approach for QSAR modeling of various biological activities using substituent electronic descriptors.
|
J Comput Chem
|
2009
|
0.75
|
54
|
Dihydropyridines and multidrug resistance: previous attempts, present state, and future trends.
|
Chem Biol Drug Des
|
2010
|
0.75
|
55
|
N-(2-(Piperazin-1-yl)phenyl)arylamide Derivatives as β-Secretase (BACE1) Inhibitors: Simple Synthesis by Ugi Four-Component Reaction and Biological Evaluation.
|
Arch Pharm (Weinheim)
|
2015
|
0.75
|
56
|
Comparative QSAR studies on toxicity of phenol derivatives using quantum topological molecular similarity indices.
|
Chem Biol Drug Des
|
2010
|
0.75
|
57
|
Design, synthesis and biological evaluation of novel anti-cytokine 1,2,4-triazine derivatives.
|
Bioorg Med Chem
|
2013
|
0.75
|
58
|
Chemical classification of the essential oils of the Iranian Salvia species in comparison with their botanical taxonomy.
|
Chem Biodivers
|
2012
|
0.75
|
59
|
Cytotoxic activity assessment, QSAR and docking study of novel bis-carboxamide derivatives of 4-pyrones synthesized by Ugi four-component reaction.
|
Eur J Med Chem
|
2013
|
0.75
|
60
|
Partial least squares-based multivariate spectral calibration method for simultaneous determination of beta-carboline derivatives in Peganum harmala seed extracts.
|
Anal Chim Acta
|
2006
|
0.75
|
61
|
A segmented principal component analysis--regression approach to QSAR study of peptides.
|
J Theor Biol
|
2012
|
0.75
|
62
|
Synthesis and cytotoxic activity of novel poly-substituted imidazo[2,1-c][1,2,4]triazin-6-amines.
|
Mol Divers
|
2015
|
0.75
|
63
|
A mechanistic QSAR study on the leishmanicidal activity of some 5-substituted-1,3,4-thiadiazole derivatives.
|
Chem Biol Drug Des
|
2007
|
0.75
|
64
|
Antioxidant activity and total phenolic content of 24 Lamiaceae species growing in Iran.
|
Nat Prod Commun
|
2010
|
0.75
|
65
|
HPLC method for analysis of a new 1,4-dihydropyridine: application to pharmacokinetic study in rabbit.
|
J Pharm Biomed Anal
|
2005
|
0.75
|