1
|
Finding the missing heritability of complex diseases.
|
Nature
|
2009
|
67.95
|
2
|
Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans.
|
Science
|
2009
|
25.61
|
3
|
Influenza-associated hospitalizations in the United States.
|
JAMA
|
2004
|
18.23
|
4
|
Characterization of the reconstructed 1918 Spanish influenza pandemic virus.
|
Science
|
2005
|
17.19
|
5
|
Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus.
|
N Engl J Med
|
2009
|
15.02
|
6
|
Probable person-to-person transmission of avian influenza A (H5N1).
|
N Engl J Med
|
2005
|
14.59
|
7
|
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses.
|
Nat Struct Mol Biol
|
2009
|
12.13
|
8
|
Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS.
|
PLoS Genet
|
2010
|
10.75
|
9
|
Prevention and control of influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010.
|
MMWR Recomm Rep
|
2010
|
10.59
|
10
|
The allelic architecture of human disease genes: common disease-common variant...or not?
|
Hum Mol Genet
|
2002
|
10.08
|
11
|
The global circulation of seasonal influenza A (H3N2) viruses.
|
Science
|
2008
|
10.05
|
12
|
Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice.
|
Science
|
2009
|
8.61
|
13
|
A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission.
|
Science
|
2007
|
8.38
|
14
|
Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States.
|
JAMA
|
2006
|
8.06
|
15
|
Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals.
|
J Virol
|
2005
|
7.88
|
16
|
Influenza-associated deaths among children in the United States, 2003-2004.
|
N Engl J Med
|
2005
|
6.83
|
17
|
Lack of transmission of H5N1 avian-human reassortant influenza viruses in a ferret model.
|
Proc Natl Acad Sci U S A
|
2006
|
6.35
|
18
|
A distinct lineage of influenza A virus from bats.
|
Proc Natl Acad Sci U S A
|
2012
|
6.27
|
19
|
Transmission of equine influenza virus to dogs.
|
Science
|
2005
|
6.11
|
20
|
SCAN: SNP and copy number annotation.
|
Bioinformatics
|
2009
|
5.96
|
21
|
Risk of influenza A (H5N1) infection among poultry workers, Hong Kong, 1997-1998.
|
J Infect Dis
|
2002
|
5.92
|
22
|
Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009.
|
MMWR Recomm Rep
|
2009
|
5.80
|
23
|
Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern.
|
Lancet
|
2005
|
5.70
|
24
|
Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2007.
|
MMWR Recomm Rep
|
2007
|
5.32
|
25
|
Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide.
|
J Infect Dis
|
2007
|
5.21
|
26
|
Prevention and Control of Influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP).
|
MMWR Recomm Rep
|
2006
|
5.19
|
27
|
Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP).
|
MMWR Recomm Rep
|
2004
|
5.00
|
28
|
Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia.
|
Nat Genet
|
2011
|
4.93
|
29
|
A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity.
|
Proc Natl Acad Sci U S A
|
2007
|
4.35
|
30
|
Germline BAP1 mutations predispose to malignant mesothelioma.
|
Nat Genet
|
2011
|
4.26
|
31
|
Rational inferences about departures from Hardy-Weinberg equilibrium.
|
Am J Hum Genet
|
2005
|
4.15
|
32
|
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
|
Nat Genet
|
2014
|
4.13
|
33
|
Evaluation of genetic variation contributing to differences in gene expression between populations.
|
Am J Hum Genet
|
2008
|
4.01
|
34
|
Global concerns regarding novel influenza A (H7N9) virus infections.
|
N Engl J Med
|
2013
|
3.88
|
35
|
Insulin gene mutations as a cause of permanent neonatal diabetes.
|
Proc Natl Acad Sci U S A
|
2007
|
3.77
|
36
|
Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP).
|
MMWR Recomm Rep
|
2005
|
3.50
|
37
|
Genetic architecture of transcript-level variation in humans.
|
Am J Hum Genet
|
2008
|
3.36
|
38
|
Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP).
|
MMWR Recomm Rep
|
2002
|
3.27
|
39
|
Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.
|
Lancet
|
2013
|
3.21
|
40
|
In vitro evolution of H5N1 avian influenza virus toward human-type receptor specificity.
|
Virology
|
2011
|
3.19
|
41
|
Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP).
|
MMWR Recomm Rep
|
2003
|
2.96
|
42
|
Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies.
|
Diabetes
|
2007
|
2.91
|
43
|
Serologic evidence of H1 swine Influenza virus infection in swine farm residents and employees.
|
Emerg Infect Dis
|
2002
|
2.75
|
44
|
Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue.
|
PLoS Genet
|
2011
|
2.68
|
45
|
Influenza vaccine strain selection and recent studies on the global migration of seasonal influenza viruses.
|
Vaccine
|
2008
|
2.56
|
46
|
Isolation and characterization of avian influenza viruses, including highly pathogenic H5N1, from poultry in live bird markets in Hanoi, Vietnam, in 2001.
|
J Virol
|
2005
|
2.51
|
47
|
Genetic analysis of human H2N2 and early H3N2 influenza viruses, 1957-1972: evidence for genetic divergence and multiple reassortment events.
|
Virology
|
2004
|
2.44
|
48
|
Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci.
|
Proc Natl Acad Sci U S A
|
2010
|
2.43
|
49
|
Genetic compatibility and virulence of reassortants derived from contemporary avian H5N1 and human H3N2 influenza A viruses.
|
PLoS Pathog
|
2008
|
2.38
|
50
|
Reassortment between avian H5N1 and human H3N2 influenza viruses in ferrets: a public health risk assessment.
|
J Virol
|
2009
|
2.33
|
51
|
A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk.
|
Cell
|
2013
|
2.28
|
52
|
Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza H5N1 viruses.
|
Virology
|
2011
|
2.28
|
53
|
Half- vs full-dose trivalent inactivated influenza vaccine (2004-2005): age, dose, and sex effects on immune responses.
|
Arch Intern Med
|
2008
|
2.24
|
54
|
Pause on avian flu transmission research.
|
Science
|
2012
|
2.24
|
55
|
Family clustering of avian influenza A (H5N1).
|
Emerg Infect Dis
|
2005
|
2.04
|
56
|
Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21.
|
Am J Hum Genet
|
2004
|
2.03
|
57
|
The neutrophil alloantigen HNA-3a (5b) is located on choline transporter-like protein 2 and appears to be encoded by an R>Q154 amino acid substitution.
|
Blood
|
2009
|
2.02
|
58
|
Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder.
|
Arch Gen Psychiatry
|
2006
|
2.02
|
59
|
A statistical method for identification of polymorphisms that explain a linkage result.
|
Am J Hum Genet
|
2002
|
1.99
|
60
|
Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP) -- United States, 2014-15 influenza season.
|
MMWR Morb Mortal Wkly Rep
|
2014
|
1.97
|
61
|
Identification of common genetic variants that account for transcript isoform variation between human populations.
|
Hum Genet
|
2008
|
1.96
|
62
|
Evolution of highly pathogenic H5N1 avian influenza viruses in Vietnam between 2001 and 2007.
|
PLoS One
|
2008
|
1.91
|
63
|
Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample.
|
Am J Hum Genet
|
2006
|
1.89
|
64
|
Pathogenesis and transmission of swine origin A(H3N2)v influenza viruses in ferrets.
|
Proc Natl Acad Sci U S A
|
2012
|
1.80
|
65
|
Polygenic virulence factors involved in pathogenesis of 1997 Hong Kong H5N1 influenza viruses in mice.
|
Virus Res
|
2007
|
1.77
|
66
|
Experimental evaluation of the FluChip diagnostic microarray for influenza virus surveillance.
|
J Clin Microbiol
|
2006
|
1.76
|
67
|
Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.
|
PLoS Genet
|
2013
|
1.68
|
68
|
Antiviral resistance during the 2009 influenza A H1N1 pandemic: public health, laboratory, and clinical perspectives.
|
Lancet Infect Dis
|
2011
|
1.66
|
69
|
Cross-protective immunity in mice induced by live-attenuated or inactivated vaccines against highly pathogenic influenza A (H5N1) viruses.
|
Vaccine
|
2006
|
1.66
|
70
|
A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose.
|
Diabetes
|
2009
|
1.65
|
71
|
Seasonal influenza vaccines.
|
Curr Top Microbiol Immunol
|
2009
|
1.63
|
72
|
Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus.
|
Am J Hum Genet
|
2002
|
1.61
|
73
|
Coverage and characteristics of the Affymetrix GeneChip Human Mapping 100K SNP set.
|
PLoS Genet
|
2006
|
1.58
|
74
|
GEL: a novel genotype calling algorithm using empirical likelihood.
|
Bioinformatics
|
2006
|
1.58
|
75
|
MChip: a tool for influenza surveillance.
|
Anal Chem
|
2006
|
1.57
|
76
|
Surveillance for influenza--United States, 1997-98, 1998-99, and 1999-00 seasons.
|
MMWR Surveill Summ
|
2002
|
1.57
|
77
|
Reappearance and global spread of variants of influenza B/Victoria/2/87 lineage viruses in the 2000-2001 and 2001-2002 seasons.
|
Virology
|
2002
|
1.57
|
78
|
Lack of evidence for human-to-human transmission of avian influenza A (H9N2) viruses in Hong Kong, China 1999.
|
Emerg Infect Dis
|
2002
|
1.54
|
79
|
On sharing quantitative trait GWAS results in an era of multiple-omics data and the limits of genomic privacy.
|
Am J Hum Genet
|
2012
|
1.49
|
80
|
Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients.
|
Clin Cancer Res
|
2011
|
1.47
|
81
|
Next generation analytic tools for large scale genetic epidemiology studies of complex diseases.
|
Genet Epidemiol
|
2011
|
1.47
|
82
|
Re: CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the Breast International Group 1-98 trial.
|
J Natl Cancer Inst
|
2012
|
1.46
|
83
|
A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci.
|
PLoS Genet
|
2011
|
1.46
|
84
|
New complexities in the genetics of stuttering: significant sex-specific linkage signals.
|
Am J Hum Genet
|
2006
|
1.46
|
85
|
The development of vaccine viruses against pandemic A(H1N1) influenza.
|
Vaccine
|
2011
|
1.44
|
86
|
Genome-wide interrogation of longitudinal FEV1 in children with asthma.
|
Am J Respir Crit Care Med
|
2014
|
1.44
|
87
|
Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines.
|
Genome Biol
|
2014
|
1.43
|
88
|
Genomewide significant linkage to stuttering on chromosome 12.
|
Am J Hum Genet
|
2005
|
1.42
|
89
|
Cancer pharmacogenomics: strategies and challenges.
|
Nat Rev Genet
|
2012
|
1.41
|
90
|
So many questions, so little time.
|
J Infect Dis
|
2012
|
1.40
|
91
|
Genetic studies of stuttering in a founder population.
|
J Fluency Disord
|
2006
|
1.39
|
92
|
Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry.
|
Carcinogenesis
|
2012
|
1.38
|
93
|
Genome-wide meta-analysis for severe diabetic retinopathy.
|
Hum Mol Genet
|
2011
|
1.36
|
94
|
Genetic architecture of microRNA expression: implications for the transcriptome and complex traits.
|
Am J Hum Genet
|
2012
|
1.36
|
95
|
Spoiling the whole bunch: quality control aimed at preserving the integrity of high-throughput genotyping.
|
Am J Hum Genet
|
2010
|
1.35
|
96
|
Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probands.
|
Am J Med Genet
|
2002
|
1.35
|
97
|
Population differences in microRNA expression and biological implications.
|
RNA Biol
|
2011
|
1.33
|
98
|
Improving influenza vaccine virus selection: report of a WHO informal consultation held at WHO headquarters, Geneva, Switzerland, 14-16 June 2010.
|
Influenza Other Respir Viruses
|
2011
|
1.32
|
99
|
Exprtarget: an integrative approach to predicting human microRNA targets.
|
PLoS One
|
2010
|
1.31
|
100
|
Receptor specificity of subtype H1 influenza A viruses isolated from swine and humans in the United States.
|
Virology
|
2011
|
1.31
|
101
|
Genome-wide association studies in pharmacogenomics: successes and lessons.
|
Pharmacogenet Genomics
|
2013
|
1.30
|
102
|
Reassortment and evolution of current human influenza A and B viruses.
|
Virus Res
|
2004
|
1.29
|
103
|
PACdb: a database for cell-based pharmacogenomics.
|
Pharmacogenet Genomics
|
2010
|
1.28
|
104
|
Identification of A/H5N1 influenza viruses using a single gene diagnostic microarray.
|
Anal Chem
|
2007
|
1.28
|
105
|
Pathogenesis, transmissibility, and ocular tropism of a highly pathogenic avian influenza A (H7N3) virus associated with human conjunctivitis.
|
J Virol
|
2013
|
1.27
|
106
|
Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure.
|
J Allergy Clin Immunol
|
2003
|
1.27
|
107
|
Robust sequence selection method used to develop the FluChip diagnostic microarray for influenza virus.
|
J Clin Microbiol
|
2006
|
1.25
|
108
|
Variants affecting exon skipping contribute to complex traits.
|
PLoS Genet
|
2012
|
1.24
|
109
|
Detection and characterization of clade 7 high pathogenicity avian influenza H5N1 viruses in chickens seized at ports of entry and live poultry markets in Vietnam.
|
Avian Dis
|
2010
|
1.23
|
110
|
Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
|
Clin Cancer Res
|
2012
|
1.22
|
111
|
Pandemic influenza planning, United States, 1978-2008.
|
Emerg Infect Dis
|
2013
|
1.22
|
112
|
Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers.
|
Transl Res
|
2011
|
1.22
|
113
|
Effect of D222G mutation in the hemagglutinin protein on receptor binding, pathogenesis and transmissibility of the 2009 pandemic H1N1 influenza virus.
|
PLoS One
|
2011
|
1.21
|
114
|
Receptor specificity of influenza A H3N2 viruses isolated in mammalian cells and embryonated chicken eggs.
|
J Virol
|
2010
|
1.21
|
115
|
Relationship of EGFR mutations, expression, amplification, and polymorphisms to epidermal growth factor receptor inhibitors in the NCI60 cell lines.
|
Clin Cancer Res
|
2007
|
1.20
|
116
|
Antigenic and genetic diversity of highly pathogenic avian influenza A (H5N1) viruses isolated in Egypt.
|
Avian Dis
|
2010
|
1.19
|
117
|
Genome-wide scan for metabolic syndrome and related quantitative traits in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25.
|
Diabetes
|
2004
|
1.19
|
118
|
Gender-specific differences in expression in human lymphoblastoid cell lines.
|
Pharmacogenet Genomics
|
2007
|
1.18
|
119
|
Intercontinental circulation of human influenza A(H1N2) reassortant viruses during the 2001-2002 influenza season.
|
J Infect Dis
|
2002
|
1.17
|
120
|
Identification of Diabetic Retinopathy Genes through a Genome-Wide Association Study among Mexican-Americans from Starr County, Texas.
|
J Ophthalmol
|
2010
|
1.14
|
121
|
Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses.
|
Mol Genet Metab
|
2006
|
1.14
|
122
|
Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees.
|
Biol Psychiatry
|
2004
|
1.13
|
123
|
Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study: common genetic variants in GCK and TCF7L2 are associated with fasting and postchallenge glucose levels in pregnancy and with the new consensus definition of gestational diabetes mellitus from the International Association of Diabetes and Pregnancy Study Groups.
|
Diabetes
|
2010
|
1.12
|
124
|
SNPs meet CNVs in genome-wide association studies: HGV2007 meeting report.
|
PLoS Genet
|
2008
|
1.11
|
125
|
A genome-wide association study of breast cancer in women of African ancestry.
|
Hum Genet
|
2012
|
1.11
|
126
|
Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects.
|
Diabetes
|
2006
|
1.09
|
127
|
Genetic risk factors for type 2 diabetes: a trans-regulatory genetic architecture?
|
Am J Hum Genet
|
2012
|
1.09
|
128
|
Using live, attenuated influenza vaccine for prevention and control of influenza: supplemental recommendations of the Advisory Committee on Immunization Practices (ACIP).
|
MMWR Recomm Rep
|
2003
|
1.08
|
129
|
Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer.
|
PLoS Genet
|
2012
|
1.08
|
130
|
Transmission studies resume for avian flu.
|
Science
|
2013
|
1.07
|
131
|
Quantification of influenza virus hemagglutinins in complex mixtures using isotope dilution tandem mass spectrometry.
|
Vaccine
|
2008
|
1.07
|
132
|
Genome-wide scan for type 2 diabetes loci in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25.
|
Diabetes
|
2004
|
1.07
|
133
|
Genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibility.
|
Blood
|
2009
|
1.06
|
134
|
Identification of genetic variants and gene expression relationships associated with pharmacogenes in humans.
|
Pharmacogenet Genomics
|
2008
|
1.06
|
135
|
Antigenic drift in the evolution of H1N1 influenza A viruses resulting from deletion of a single amino acid in the haemagglutinin gene.
|
J Gen Virol
|
2007
|
1.05
|
136
|
Strengthening the influenza vaccine virus selection and development process: outcome of the 2nd WHO Informal Consultation for Improving Influenza Vaccine Virus Selection held at the Centre International de Conférences (CICG) Geneva, Switzerland, 7 to 9 December 2011.
|
Vaccine
|
2013
|
1.05
|
137
|
An exponential combination procedure for set-based association tests in sequencing studies.
|
Am J Hum Genet
|
2012
|
1.05
|
138
|
Meta-analysis of 23 type 2 diabetes linkage studies from the International Type 2 Diabetes Linkage Analysis Consortium.
|
Hum Hered
|
2007
|
1.04
|
139
|
Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.
|
Diabetes
|
2013
|
1.03
|
140
|
A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.
|
Cancer Epidemiol Biomarkers Prev
|
2014
|
1.03
|
141
|
A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.
|
Metabolism
|
2003
|
1.02
|
142
|
Psychiatrists' attitudes, knowledge, and experience regarding genetics: a preliminary study.
|
Genet Med
|
2008
|
1.00
|
143
|
Population differences in the rate of proliferation of international HapMap cell lines.
|
Am J Hum Genet
|
2010
|
1.00
|
144
|
Characterization of a highly pathogenic avian influenza H5N1 virus sublineage in poultry seized at ports of entry into Vietnam.
|
Virology
|
2009
|
0.99
|
145
|
Interpreting P values in pharmacogenetic studies: a call for process and perspective.
|
J Clin Oncol
|
2007
|
0.99
|
146
|
Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci.
|
J Allergy Clin Immunol
|
2006
|
0.99
|
147
|
Comparative immunogenicity and cross-clade protective efficacy of mammalian cell-grown inactivated and live attenuated H5N1 reassortant vaccines in ferrets.
|
J Infect Dis
|
2011
|
0.99
|
148
|
Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans.
|
PLoS One
|
2011
|
0.99
|
149
|
Loci nominally associated with autism from genome-wide analysis show enrichment of brain expression quantitative trait loci but not lymphoblastoid cell line expression quantitative trait loci.
|
Mol Autism
|
2012
|
0.98
|
150
|
Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome.
|
J Clin Endocrinol Metab
|
2002
|
0.97
|
151
|
Genetic analysis of avian influenza A viruses isolated from domestic waterfowl in live-bird markets of Hanoi, Vietnam, preceding fatal H5N1 human infections in 2004.
|
Arch Virol
|
2009
|
0.97
|
152
|
Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects.
|
Diabetes
|
2003
|
0.97
|
153
|
Influenza A(H1N1)pdm09 virus among healthy show pigs, United States.
|
Emerg Infect Dis
|
2012
|
0.96
|
154
|
Variation in the calpain-10 gene affects blood glucose levels in the British population.
|
Diabetes
|
2002
|
0.96
|
155
|
Influenza surveillance with rapid diagnostic tests.
|
Clin Infect Dis
|
2002
|
0.96
|
156
|
Psychiatrists' attitudes regarding genetic testing and patient safeguards: a preliminary study.
|
Genet Test
|
2008
|
0.96
|
157
|
Population-specific GSTM1 copy number variation.
|
Hum Mol Genet
|
2008
|
0.96
|
158
|
Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases.
|
J Am Med Inform Assoc
|
2013
|
0.95
|
159
|
Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymorphism in the PPARgamma gene.
|
J Clin Endocrinol Metab
|
2002
|
0.95
|
160
|
Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects.
|
J Allergy Clin Immunol
|
2012
|
0.95
|
161
|
Fine mapping of breast cancer genome-wide association studies loci in women of African ancestry identifies novel susceptibility markers.
|
Carcinogenesis
|
2013
|
0.95
|
162
|
Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians.
|
Diabetes
|
2002
|
0.94
|
163
|
Development of an influenza virologic risk assessment tool.
|
Avian Dis
|
2012
|
0.94
|
164
|
Structural stability of influenza A(H1N1)pdm09 virus hemagglutinins.
|
J Virol
|
2014
|
0.94
|
165
|
Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians.
|
J Clin Endocrinol Metab
|
2002
|
0.93
|
166
|
Confirmed locus on chromosome 11p and candidate loci on 6q and 8p for the triglyceride and cholesterol traits of combined hyperlipidemia.
|
Arterioscler Thromb Vasc Biol
|
2003
|
0.93
|
167
|
Copy number polymorphisms and anticancer pharmacogenomics.
|
Genome Biol
|
2011
|
0.93
|
168
|
Updated preparedness and response framework for influenza pandemics.
|
MMWR Recomm Rep
|
2014
|
0.92
|
169
|
A genome-wide integrative study of microRNAs in human liver.
|
BMC Genomics
|
2013
|
0.92
|
170
|
Influenza A virus nucleoprotein exploits Hsp40 to inhibit PKR activation.
|
PLoS One
|
2011
|
0.92
|
171
|
The chromosome 3q25 genomic region is associated with measures of adiposity in newborns in a multi-ethnic genome-wide association study.
|
Hum Mol Genet
|
2013
|
0.92
|
172
|
Comprehensive survey of SNPs in the Affymetrix exon array using the 1000 Genomes dataset.
|
PLoS One
|
2010
|
0.92
|
173
|
Genetic bases of the temperature-sensitive phenotype of a master donor virus used in live attenuated influenza vaccines: A/Leningrad/134/17/57 (H2N2).
|
Virology
|
2011
|
0.92
|
174
|
Poly-omic prediction of complex traits: OmicKriging.
|
Genet Epidemiol
|
2014
|
0.91
|
175
|
Evidence for a susceptibility locus on chromosome 10p15 in early-onset obsessive-compulsive disorder.
|
Biol Psychiatry
|
2007
|
0.90
|
176
|
Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.
|
Am J Psychiatry
|
2014
|
0.90
|
177
|
Human genetics: an expression of interest.
|
Nature
|
2004
|
0.89
|
178
|
Identification of novel germline polymorphisms governing capecitabine sensitivity.
|
Cancer
|
2012
|
0.89
|
179
|
Expression and alternative splicing of folate pathway genes in HapMap lymphoblastoid cell lines.
|
Pharmacogenomics
|
2009
|
0.89
|
180
|
Development of Framework for Assessing Influenza Virus Pandemic Risk.
|
Emerg Infect Dis
|
2015
|
0.89
|
181
|
Locus on chromosome 6p linked to elevated HDL cholesterol serum levels and to protection against premature atherosclerosis in a kindred with familial hypercholesterolemia.
|
Circ Res
|
2003
|
0.88
|
182
|
Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome.
|
J Clin Endocrinol Metab
|
2002
|
0.88
|
183
|
H7N9: preparing for the unexpected in influenza.
|
Annu Rev Med
|
2014
|
0.88
|
184
|
Molecular epidemiology of influenza A(H3N2) virus reinfections.
|
J Infect Dis
|
2002
|
0.88
|
185
|
A pharmacogene database enhanced by the 1000 Genomes Project.
|
Pharmacogenet Genomics
|
2009
|
0.88
|
186
|
Genetic association signal near NTN4 in Tourette syndrome.
|
Ann Neurol
|
2014
|
0.87
|
187
|
Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome.
|
J Clin Endocrinol Metab
|
2002
|
0.87
|
188
|
Diagnostic microarray for influenza B viruses.
|
Anal Chem
|
2007
|
0.87
|
189
|
Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.
|
Blood
|
2013
|
0.87
|
190
|
Influenza A viral nucleoprotein interacts with cytoskeleton scaffolding protein α-actinin-4 for viral replication.
|
FEBS J
|
2014
|
0.86
|
191
|
Obesity and hyperinsulinemia in a family with pancreatic agenesis and MODY caused by the IPF1 mutation Pro63fsX60.
|
Transl Res
|
2010
|
0.86
|
192
|
Parent-of-origin effects of the serotonin transporter gene associated with autism.
|
Am J Med Genet B Neuropsychiatr Genet
|
2010
|
0.86
|
193
|
Improving influenza vaccine virus selection: report of a WHO informal consultation held at WHO headquarters, Geneva, Switzerland, 14-16 June 2010.
|
Influenza Other Respir Viruses
|
2013
|
0.85
|
194
|
Integrative genomics: quantifying significance of phenotype-genotype relationships from multiple sources of high-throughput data.
|
Front Genet
|
2013
|
0.85
|
195
|
Transmission disequilibrium testing of the chromosome 15q11-q13 region in autism.
|
Am J Med Genet B Neuropsychiatr Genet
|
2008
|
0.85
|
196
|
Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population.
|
Mol Genet Metab
|
2004
|
0.85
|
197
|
Reconstructability analysis as a tool for identifying gene-gene interactions in studies of human diseases.
|
Stat Appl Genet Mol Biol
|
2010
|
0.85
|
198
|
SCAN: a systems biology approach to pharmacogenomic discovery.
|
Methods Mol Biol
|
2013
|
0.85
|
199
|
MERLIN...and the geneticist's stone?
|
Nat Genet
|
2002
|
0.85
|
200
|
Genetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorder.
|
Proc Natl Acad Sci U S A
|
2014
|
0.84
|
201
|
Factors that impact susceptibility to fiber-induced health effects.
|
J Toxicol Environ Health B Crit Rev
|
2011
|
0.84
|
202
|
Replication analysis for severe diabetic retinopathy.
|
Invest Ophthalmol Vis Sci
|
2012
|
0.84
|
203
|
Trans-population analysis of genetic mechanisms of ethnic disparities in neuroblastoma survival.
|
J Natl Cancer Inst
|
2012
|
0.84
|
204
|
The use of genomic information to optimize cancer chemotherapy.
|
Semin Oncol
|
2011
|
0.84
|
205
|
Adamantane-resistant influenza infection during the 2004-05 season.
|
Emerg Infect Dis
|
2008
|
0.84
|
206
|
Evaluation of MChip with historic subtype H1N1 influenza A viruses, including the 1918 "Spanish Flu" strain.
|
J Clin Microbiol
|
2007
|
0.84
|
207
|
The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy.
|
PLoS One
|
2012
|
0.83
|
208
|
Biomolecular Systems of Disease Buried Across Multiple GWAS Unveiled by Information Theory and Ontology.
|
AMIA Jt Summits Transl Sci Proc
|
2010
|
0.83
|
209
|
Influenza A virus neuraminidase protein enhances cell survival through interaction with carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) protein.
|
J Biol Chem
|
2012
|
0.83
|
210
|
Inactivated and live attenuated influenza vaccines in young children--how do they compare?
|
N Engl J Med
|
2007
|
0.82
|
211
|
Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1.
|
Am J Med Genet B Neuropsychiatr Genet
|
2008
|
0.82
|
212
|
Quantification of immunoreactive viral influenza proteins by immunoaffinity capture and isotope-dilution liquid chromatography-tandem mass spectrometry.
|
Anal Chem
|
2011
|
0.82
|
213
|
Influenza vaccination among the elderly in the United States.
|
Arch Intern Med
|
2005
|
0.81
|
214
|
Transformation of a rural community for active living.
|
Fam Community Health
|
2011
|
0.81
|
215
|
Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry.
|
Breast Cancer Res Treat
|
2011
|
0.81
|
216
|
Integrative analyses of genetic variation, epigenetic regulation, and the transcriptome to elucidate the biology of platinum sensitivity.
|
BMC Genomics
|
2014
|
0.80
|
217
|
Characterization of reverse genetics-derived cold-adapted master donor virus A/Leningrad/134/17/57 (H2N2) and reassortants with H5N1 surface genes in a mouse model.
|
Clin Vaccine Immunol
|
2014
|
0.80
|
218
|
Concordant gene expression in leukemia cells and normal leukocytes is associated with germline cis-SNPs.
|
PLoS One
|
2008
|
0.80
|
219
|
Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry.
|
Cancer Epidemiol Biomarkers Prev
|
2012
|
0.80
|
220
|
Haplotype structure and phylogenetic shadowing of a hypervariable region in the CAPN10 gene.
|
Hum Genet
|
2005
|
0.80
|
221
|
Identifying plausible genetic models based on association and linkage results: application to type 2 diabetes.
|
Genet Epidemiol
|
2012
|
0.80
|
222
|
Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population.
|
J Hum Genet
|
2005
|
0.79
|
223
|
Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome.
|
Diabetes Res Clin Pract
|
2009
|
0.79
|
224
|
Patterns of linkage disequilibrium in the type 2 diabetes gene calpain-10.
|
Diabetes
|
2005
|
0.78
|
225
|
Institutional Profile: University of Chicago Center for Personalized Therapeutics: research, education and implementation science.
|
Pharmacogenomics
|
2013
|
0.77
|
226
|
Transcription factor ETV1 is essential for rapid conduction in the heart.
|
J Clin Invest
|
2016
|
0.77
|
227
|
Prospecting the influenza hemagglutinin to develop universal vaccines.
|
Clin Infect Dis
|
2011
|
0.77
|
228
|
Quantitative allelic test--a fast test for very large association studies.
|
Genet Epidemiol
|
2013
|
0.77
|
229
|
Comprehensive evaluation of the contribution of X chromosome genes to platinum sensitivity.
|
Mol Cancer Ther
|
2011
|
0.75
|
230
|
XIth International Symposium on Respiratory Viral Infections.
|
Influenza Other Respir Viruses
|
2011
|
0.75
|