PubRank

Donald M McDonald

Author PubWeight™ 136.92‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J Clin Invest 2006 6.12
2 VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am J Physiol Heart Circ Physiol 2005 5.56
3 Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am J Pathol 2002 5.04
4 Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am J Pathol 2004 4.47
5 Functionally specialized junctions between endothelial cells of lymphatic vessels. J Exp Med 2007 4.10
6 Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest 2005 4.09
7 Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nat Med 2004 3.64
8 Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis. J Clin Invest 2004 3.53
9 Cellular abnormalities of blood vessels as targets in cancer. Curr Opin Genet Dev 2005 3.38
10 Cellular changes in normal blood capillaries undergoing regression after inhibition of VEGF signaling. Am J Physiol Heart Circ Physiol 2005 3.28
11 Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity. Genes Dev 2008 2.91
12 Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumors. Cancer Discov 2012 2.57
13 Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors. Am J Pathol 2003 2.37
14 Angiopoietin-1 decreases plasma leakage by reducing number and size of endothelial gaps in venules. Am J Physiol Heart Circ Physiol 2005 2.34
15 Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning. J Exp Med 2009 2.34
16 Long-term and sustained COMP-Ang1 induces long-lasting vascular enlargement and enhanced blood flow. Circ Res 2005 2.14
17 Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells. Proc Natl Acad Sci U S A 2006 2.03
18 VEGF and c-Met blockade amplify angiogenesis inhibition in pancreatic islet cancer. Cancer Res 2011 1.92
19 Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth. Cancer Res 2010 1.90
20 Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels. Am J Pathol 2009 1.87
21 Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102. Cancer Res 2007 1.83
22 Controlling escape from angiogenesis inhibitors. Nat Rev Cancer 2012 1.81
23 In situ force mapping of mammary gland transformation. Integr Biol (Camb) 2011 1.78
24 TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice. J Clin Invest 2009 1.76
25 Iron administration before stem cell harvest enables MR imaging tracking after transplantation. Radiology 2013 1.70
26 Markers for microscopic imaging of lymphangiogenesis and angiogenesis. Ann N Y Acad Sci 2008 1.62
27 The hepatocyte growth factor/c-Met signaling pathway as a therapeutic target to inhibit angiogenesis. BMB Rep 2008 1.57
28 Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors. Cancer Res 2011 1.51
29 Transgenic overexpression of interleukin-1β induces persistent lymphangiogenesis but not angiogenesis in mouse airways. Am J Pathol 2013 1.50
30 Disease-specific gene expression profiling in multiple models of lung disease. Am J Respir Crit Care Med 2007 1.46
31 Age-related changes in vascular endothelial growth factor dependency and angiopoietin-1-induced plasticity of adult blood vessels. Circ Res 2004 1.45
32 Expression of genes involved in vascular development and angiogenesis in endothelial cells of adult lung. Am J Physiol Heart Circ Physiol 2003 1.45
33 Regulated angiogenesis and vascular regression in mice overexpressing vascular endothelial growth factor in airways. Am J Pathol 2004 1.39
34 Effect of inhibition of vascular endothelial growth factor signaling on distribution of extravasated antibodies in tumors. Cancer Res 2006 1.39
35 Angiopoietin 1 causes vessel enlargement, without angiogenic sprouting, during a critical developmental period. Development 2005 1.38
36 Cell labeling with the positive MR contrast agent Gadofluorine M. Eur Radiol 2007 1.32
37 Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung. Proc Natl Acad Sci U S A 2006 1.32
38 Context-dependent role of angiopoietin-1 inhibition in the suppression of angiogenesis and tumor growth: implications for AMG 386, an angiopoietin-1/2-neutralizing peptibody. Mol Cancer Ther 2010 1.27
39 Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees. Cell Tissue Res 2008 1.26
40 Probing the structural and molecular diversity of tumor vasculature. Trends Mol Med 2002 1.26
41 Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection. Am J Pathol 2005 1.22
42 Mosaic tumor vessels: cellular basis and ultrastructure of focal regions lacking endothelial cell markers. Cancer Res 2005 1.21
43 Cellular source and amount of vascular endothelial growth factor and platelet-derived growth factor in tumors determine response to angiogenesis inhibitors. Cancer Res 2009 1.20
44 Soluble receptor-mediated selective inhibition of VEGFR and PDGFRbeta signaling during physiologic and tumor angiogenesis. Proc Natl Acad Sci U S A 2008 1.20
45 Lymphotoxin-alpha contributes to lymphangiogenesis. Blood 2010 1.19
46 Vascular permeability during antiangiogenesis treatment: MR imaging assay results as biomarker for subsequent tumor growth in rats. Radiology 2008 1.17
47 Relaxation effects of ferucarbotran-labeled mesenchymal stem cells at 1.5T and 3T: discrimination of viable from lysed cells. Magn Reson Med 2009 1.17
48 Mast cells protect mice from Mycoplasma pneumonia. Am J Respir Crit Care Med 2005 1.16
49 Plasticity of button-like junctions in the endothelium of airway lymphatics in development and inflammation. Am J Pathol 2012 1.15
50 In vivo actions of angiopoietins on quiescent and remodeling blood and lymphatic vessels in mouse airways and skin. Arterioscler Thromb Vasc Biol 2006 1.15
51 Immune complex-dependent remodeling of the airway vasculature in response to a chronic bacterial infection. J Immunol 2005 1.14
52 Uniform overexpression and rapid accessibility of alpha5beta1 integrin on blood vessels in tumors. Am J Pathol 2005 1.12
53 Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation. Am J Pathol 2011 1.08
54 Angiopoietin-2-driven vascular remodeling in airway inflammation. Am J Pathol 2010 1.07
55 Steroid-resistant lymphatic remodeling in chronically inflamed mouse airways. Am J Pathol 2010 1.06
56 Rapid access of antibodies to alpha5beta1 integrin overexpressed on the luminal surface of tumor blood vessels. Cancer Res 2005 1.06
57 MR signal characteristics of viable and apoptotic human mesenchymal stem cells in matrix-associated stem cell implants for treatment of osteoarthritis. Invest Radiol 2010 1.02
58 alpha5beta1 Integrin blockade inhibits lymphangiogenesis in airway inflammation. Am J Pathol 2009 1.01
59 Capillary defects and exaggerated inflammatory response in the airways of EphA2-deficient mice. Am J Pathol 2009 1.00
60 Matrix metalloproteinase-2 and -9 expression increases in Mycoplasma-infected airways but is not required for microvascular remodeling. Am J Physiol Lung Cell Mol Physiol 2004 0.99
61 Increased vascular delivery and efficacy of chemotherapy after inhibition of platelet-derived growth factor-B. Am J Pathol 2011 0.99
62 The biologic basis of in vivo angiogenesis imaging. Front Biosci 2007 0.98
63 Angiogenesis with pericyte abnormalities in a transgenic model of prostate carcinoma. Cancer 2005 0.97
64 Vascular endothelial growth factor-A and platelet-derived growth factor-B combination gene therapy prolongs angiogenic effects via recruitment of interstitial mononuclear cells and paracrine effects rather than improved pericyte coverage of angiogenic vessels. Circ Res 2008 0.96
65 Therapeutic angiogenesis due to balanced single-vector delivery of VEGF and PDGF-BB. FASEB J 2012 0.96
66 Inhibition of c-Met reduces lymphatic metastasis in RIP-Tag2 transgenic mice. Cancer Res 2013 0.92
67 Correlative dynamic contrast MRI and microscopic assessments of tumor vascularity in RIP-Tag2 transgenic mice. Magn Reson Med 2009 0.91
68 Antiangiogenic therapy decreases integrin expression in normalized tumor blood vessels. Cancer Res 2006 0.91
69 Mechanisms of increased immunogenicity for DNA-based vaccines adsorbed onto cationic microparticles. Cell Immunol 2003 0.90
70 Pulmonary lymphangiectasia resulting from vascular endothelial growth factor-C overexpression during a critical period. Circ Res 2014 0.90
71 Shear stress-induced upregulation of connexin 43 expression in endothelial cells on upstream surfaces of rat cardiac valves. Histochem Cell Biol 2004 0.89
72 Molecular determinants of lung development. Ann Am Thorac Soc 2013 0.89
73 IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia. Int Immunol 2013 0.88
74 Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation. Am J Pathol 2010 0.88
75 Ricinus communis agglutinin I leads to rapid down-regulation of VEGFR-2 and endothelial cell apoptosis in tumor blood vessels. Am J Pathol 2010 0.86
76 Permeability to macromolecular contrast media quantified by dynamic MRI correlates with tumor tissue assays of vascular endothelial growth factor (VEGF). Eur J Radiol 2011 0.83
77 Magnetic resonance imaging for monitoring the effects of thalidomide on experimental human breast cancers. Eur Radiol 2008 0.83
78 Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation. J Clin Invest 2016 0.82
79 Rapid remodeling of airway vascular architecture at birth. Dev Dyn 2010 0.81
80 Tie1 controls angiopoietin function in vascular remodeling and inflammation. J Clin Invest 2016 0.81
81 Lymphangiogenesis and hemangiogenesis: potential targets for therapy. J Surg Oncol 2011 0.80
82 Cathepsin L protects mice from mycoplasmal infection and is essential for airway lymphangiogenesis. Am J Respir Cell Mol Biol 2013 0.79
83 Plasticity of airway lymphatics in development and disease. Adv Anat Embryol Cell Biol 2014 0.79
84 Magnetic resonance imaging assays for dimethyl sulfoxide effect on cancer vasculature. Invest Radiol 2008 0.78
85 Rapid changes in shape and number of MHC class II expressing cells in rat airways after Mycoplasma pulmonis infection. Cell Immunol 2002 0.77