PubRank

Herbert Y Lin

Author PubWeight™ 86.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet 2006 8.32
2 Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol 2007 8.08
3 BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet 2009 4.84
4 Local proliferation dominates lesional macrophage accumulation in atherosclerosis. Nat Med 2013 4.14
5 Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. J Clin Invest 2007 4.09
6 Differential regulation of myeloid leukemias by the bone marrow microenvironment. Nat Med 2013 2.48
7 Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor. J Biol Chem 2005 2.07
8 Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. Blood 2008 2.01
9 Mechanisms of anemia in CKD. J Am Soc Nephrol 2012 1.91
10 DRAGON, a bone morphogenetic protein co-receptor. J Biol Chem 2005 1.89
11 Divergent roles of Smad3 and PI3-kinase in murine adriamycin nephropathy indicate distinct mechanisms of proteinuria and fibrogenesis. Kidney Int 2012 1.66
12 DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci 2004 1.64
13 Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats. Blood 2011 1.63
14 Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation. Am J Hematol 2012 1.52
15 Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis. Gastroenterology 2009 1.51
16 Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice. J Clin Invest 2009 1.48
17 Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4. J Biol Chem 2007 1.45
18 Molecular mechanisms of hepcidin regulation: implications for the anemia of CKD. Am J Kidney Dis 2010 1.43
19 BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. Genes Dev 2004 1.40
20 Statement of concern about a commercial assay used to measure soluble hemojuvelin in humans. Am J Nephrol 2012 1.31
21 The liver: conductor of systemic iron balance. Blood 2013 1.30
22 BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice. Gastroenterology 2010 1.22
23 The RGM/DRAGON family of BMP co-receptors. Cytokine Growth Factor Rev 2009 1.21
24 Regulation of TMPRSS6 by BMP6 and iron in human cells and mice. Blood 2011 1.19
25 Aquaporin 2 (AQP2) and vasopressin type 2 receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in 'endocytosis-resistant' membrane domains after vasopressin treatment. Biol Cell 2006 1.14
26 Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor. Diabetes 2007 1.11
27 Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages. J Immunol 2010 1.08
28 The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease. Inflamm Bowel Dis 2011 1.05
29 The molecular pathogenesis of hereditary hemochromatosis. Semin Liver Dis 2011 1.03
30 Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway. Am J Physiol Cell Physiol 2005 1.01
31 Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity. Circulation 2014 0.99
32 Functional role of the NPxxY motif in internalization of the type 2 vasopressin receptor in LLC-PK1 cells. Am J Physiol Cell Physiol 2003 0.99
33 Dragon enhances BMP signaling and increases transepithelial resistance in kidney epithelial cells. J Am Soc Nephrol 2010 0.98
34 Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe. Gastroenterology 2011 0.98
35 Reconstitution and analysis of soluble inhibin and activin receptor complexes in a cell-free system. J Biol Chem 2004 0.95
36 Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation. Am J Physiol Cell Physiol 2003 0.95
37 Altered hepatic BMP signaling pathway in human HFE hemochromatosis. Blood Cells Mol Dis 2010 0.93
38 Localization and action of Dragon (repulsive guidance molecule b), a novel bone morphogenetic protein coreceptor, throughout the reproductive axis. Endocrinology 2005 0.93
39 Hepcidin regulation by BMP signaling in macrophages is lipopolysaccharide dependent. PLoS One 2012 0.91
40 Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs). PLoS One 2012 0.91
41 The BMP coreceptor RGMb promotes while the endogenous BMP antagonist noggin reduces neurite outgrowth and peripheral nerve regeneration by modulating BMP signaling. J Neurosci 2011 0.90
42 BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model. Neurobiol Dis 2010 0.89
43 A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum. Haematologica 2012 0.88
44 Effects of the renal medullary pH and ionic environment on vasopressin binding and signaling. Kidney Int 2008 0.88
45 A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats. Nephrol Dial Transplant 2013 0.88
46 Differential actions of follistatin and follistatin-like 3. Mol Cell Endocrinol 2004 0.87
47 Alix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R. Am J Physiol Renal Physiol 2007 0.86
48 In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2. J Biol Chem 2004 0.83
49 Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice. Int Orthop 2014 0.81
50 Dragon (repulsive guidance molecule RGMb) inhibits E-cadherin expression and induces apoptosis in renal tubular epithelial cells. J Biol Chem 2013 0.80
51 The soluble transforming growth factor-beta receptor: advantages and applications. Int J Biochem Cell Biol 2008 0.79
52 BMP signaling modulates hepcidin expression in zebrafish embryos independent of hemojuvelin. PLoS One 2011 0.79
53 Visualizing microtubule-dependent vasopressin type 2 receptor trafficking using a new high-affinity fluorescent vasopressin ligand. Endocrinology 2011 0.77
54 Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin. Am J Physiol Renal Physiol 2012 0.76
55 BuMPing iron with modified heparins. Blood 2014 0.75