Published in J Biol Chem on January 25, 2005
A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants. Mol Cell (2009) 1.95
Structure of the calcineurin-NFAT complex: defining a T cell activation switch using solution NMR and crystal coordinates. Structure (2007) 1.02
Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis. J Biol Chem (2008) 1.01
Inhibiting the calcineurin-NFAT (nuclear factor of activated T cells) signaling pathway with a regulator of calcineurin-derived peptide without affecting general calcineurin phosphatase activity. J Biol Chem (2009) 0.99
The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators. Proc Natl Acad Sci U S A (2009) 0.94
Calcium-dependent transcription of cytokine genes in T lymphocytes. Pflugers Arch (2007) 0.91
Calcineurin-mediated dephosphorylation of synaptotagmin VI is necessary for acrosomal exocytosis. J Biol Chem (2010) 0.84
Therapeutic blockade of T-cell antigen receptor signal transduction and costimulation in autoimmune disease. Adv Exp Med Biol (2008) 0.82
Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. FASEB J (2007) 2.30
A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants. Mol Cell (2009) 1.95
Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex. Neuron (2010) 1.55
The non-canonical NOTCH ligand DLK1 exhibits a novel vascular role as a strong inhibitor of angiogenesis. Cardiovasc Res (2011) 1.48
Cux-2 controls the proliferation of neuronal intermediate precursors of the cortical subventricular zone. Cereb Cortex (2007) 1.43
Cyclooxygenase-2: a therapeutic target in angiogenesis. Trends Mol Med (2003) 1.38
Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. Immunity (2010) 1.35
Inhibitors of the calcineurin/NFAT pathway. Curr Med Chem (2004) 1.33
Blockade of NFAT activation by the second calcineurin binding site. J Biol Chem (2006) 1.24
Turning astrocytes from the rostral migratory stream into neurons: a role for the olfactory sensory organ. J Neurosci (2008) 1.17
Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism. J Biol Chem (2002) 1.15
The up-regulation of human caspase-8 by interferon-gamma in breast tumor cells requires the induction and action of the transcription factor interferon regulatory factor-1. J Biol Chem (2004) 1.13
Prostanoid signal transduction and gene expression in the endothelium: role in cardiovascular diseases. Cardiovasc Res (2006) 1.08
Cux-1 and Cux-2 control the development of Reelin expressing cortical interneurons. Dev Neurobiol (2008) 1.07
Statistical model to analyze quantitative proteomics data obtained by 18O/16O labeling and linear ion trap mass spectrometry: application to the study of vascular endothelial growth factor-induced angiogenesis in endothelial cells. Mol Cell Proteomics (2009) 1.06
PGE2 induces angiogenesis via MT1-MMP-mediated activation of the TGFbeta/Alk5 signaling pathway. Blood (2008) 1.05
General statistical framework for quantitative proteomics by stable isotope labeling. J Proteome Res (2014) 1.04
A robust method for quantitative high-throughput analysis of proteomes by 18O labeling. Mol Cell Proteomics (2010) 1.03
Depolarization of neural cells induces transcription of the Down syndrome critical region 1 isoform 4 via a calcineurin/nuclear factor of activated T cells-dependent pathway. J Biol Chem (2005) 1.01
Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis. J Biol Chem (2008) 1.01
NFATc3 regulates the transcription of genes involved in T-cell activation and angiogenesis. Blood (2011) 1.01
c-Jun N-terminal kinase (JNK) positively regulates NFATc2 transactivation through phosphorylation within the N-terminal regulatory domain. J Biol Chem (2005) 0.99
Calcium/calcineurin signaling in primary cortical astrocyte cultures: Rcan1-4 and cyclooxygenase-2 as NFAT target genes. Glia (2008) 0.97
The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators. Proc Natl Acad Sci U S A (2009) 0.94
COX-2 limits prostanoid production in activated HUVECs and is a source of PGH2 for transcellular metabolism to PGE2 by tumor cells. Arterioscler Thromb Vasc Biol (2009) 0.94
High-sensitivity analysis of specific peptides in complex samples by selected MS/MS ion monitoring and linear ion trap mass spectrometry: application to biological studies. J Mass Spectrom (2007) 0.93
Prostanoids in tumor angiogenesis: therapeutic intervention beyond COX-2. Trends Mol Med (2012) 0.93
Regulator of calcineurin 1 mediates pathological vascular wall remodeling. J Exp Med (2011) 0.90
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) decoy receptor TRAIL-R3 is up-regulated by p53 in breast tumor cells through a mechanism involving an intronic p53-binding site. J Biol Chem (2003) 0.88
Calcium-dependent expression of TNF-alpha in neural cells is mediated by the calcineurin/NFAT pathway. Mol Cell Neurosci (2006) 0.87
Regulator of calcineurin 1 (Rcan1) has a protective role in brain ischemia/reperfusion injury. J Neuroinflammation (2012) 0.84
Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling. J Clin Invest (2015) 0.84
Quantitative in-depth analysis of the dynamic secretome of activated Jurkat T-cells. J Proteomics (2011) 0.83
Systematic characterization of phosphorylation sites in NFATc2 by linear ion trap mass spectrometry. Proteomics (2006) 0.82
Characterization of p53-mediated up-regulation of CD95 gene expression upon genotoxic treatment in human breast tumor cells. J Biol Chem (2003) 0.81
A major role for RCAN1 in atherosclerosis progression. EMBO Mol Med (2013) 0.80
The hepatitis B virus X protein binds to and activates the NH(2)-terminal trans-activation domain of nuclear factor of activated T cells-1. Virology (2002) 0.78
Transcription initiation sites and promoter structure of the human TRAIL-R3 gene. FEBS Lett (2002) 0.77
Transcriptional regulation of the TRAIL-R3 gene. Vitam Horm (2004) 0.76
Madrid center not quite in limbo. Science (2005) 0.75