Published in Blood on June 09, 2008
Pulmonary fibrosis: pathogenesis, etiology and regulation. Mucosal Immunol (2009) 3.13
The parallel lives of angiogenesis and immunosuppression: cancer and other tales. Nat Rev Immunol (2011) 1.82
Extracellular matrix, inflammation, and the angiogenic response. Cardiovasc Res (2010) 1.45
Stromal regulation of vessel stability by MMP14 and TGFbeta. Dis Model Mech (2010) 1.35
Membrane-associated matrix proteolysis and heart failure. Circ Res (2013) 1.35
PGE2 promotes angiogenesis through EP4 and PKA Cγ pathway. Blood (2011) 1.10
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells. J Neuroinflammation (2009) 1.10
Secretion of vascular endothelial growth factor by oral squamous cell carcinoma cells skews endothelial cells to suppress T-cell functions. Hum Immunol (2009) 1.03
Matrix metalloproteinase inhibitors as investigative tools in the pathogenesis and management of vascular disease. EXS (2012) 1.03
MT1-MMP regulates the turnover and endocytosis of extracellular matrix fibronectin. J Cell Sci (2011) 1.02
Interaction between head and neck squamous cell carcinoma cells and fibroblasts in the biosynthesis of PGE2. J Lipid Res (2012) 1.01
Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy. J Natl Cancer Inst (2015) 0.97
Orchestration of angiogenesis by immune cells. Front Oncol (2014) 0.97
Drug resistance associated with antiangiogenesis therapy. Semin Cancer Biol (2009) 0.95
Tumor secretion of VEGF induces endothelial cells to suppress T cell functions through the production of PGE2. J Immunother (2010) 0.94
n-Butyl benzyl phthalate promotes breast cancer progression by inducing expression of lymphoid enhancer factor 1. PLoS One (2012) 0.91
Regulation of endothelial cell functions by basement membrane- and arachidonic acid-derived products. Wiley Interdiscip Rev Syst Biol Med (2010) 0.88
Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm. J Lipid Res (2013) 0.87
Combined histone deacetylase and cyclooxygenase inhibition achieves enhanced antiangiogenic effects in lung cancer cells. Mol Carcinog (2011) 0.86
The lectin concanavalin-A signals MT1-MMP catalytic independent induction of COX-2 through an IKKgamma/NF-kappaB-dependent pathway. J Cell Commun Signal (2010) 0.84
MT1-MMP expression level status dictates the in vitro action of lupeol on inflammatory biomarkers MMP-9 and COX-2 in medulloblastoma cells. Inflammopharmacology (2012) 0.77
Tissue Inhibitor of Metalloproteinase-2 Suppresses Collagen Synthesis in Cultured Keloid Fibroblasts. Plast Reconstr Surg Glob Open (2015) 0.75
Matrix Metalloproteinase Inhibitors as Investigational and Therapeutic Tools in Unrestrained Tissue Remodeling and Pathological Disorders. Prog Mol Biol Transl Sci (2017) 0.75
Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. FASEB J (2007) 2.30
MT1-MMP proinvasive activity is regulated by a novel Rab8-dependent exocytic pathway. EMBO J (2007) 2.16
A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants. Mol Cell (2009) 1.95
MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling. Dev Cell (2010) 1.87
Angiogenesis in chronic inflammatory liver disease. Hepatology (2004) 1.57
Assessment of optimal virus-mediated growth factor gene delivery for human cutaneous wound healing enhancement. J Invest Dermatol (2008) 1.56
The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression. J Clin Invest (2002) 1.55
Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex. Neuron (2010) 1.55
ECM regulates MT1-MMP localization with beta1 or alphavbeta3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells. J Cell Biol (2002) 1.48
The non-canonical NOTCH ligand DLK1 exhibits a novel vascular role as a strong inhibitor of angiogenesis. Cardiovasc Res (2011) 1.48
Cux-2 controls the proliferation of neuronal intermediate precursors of the cortical subventricular zone. Cereb Cortex (2007) 1.43
Distinctive functions of membrane type 1 matrix-metalloprotease (MT1-MMP or MMP-14) in lung and submandibular gland development are independent of its role in pro-MMP-2 activation. Dev Biol (2005) 1.42
Membrane type 1-matrix metalloproteinase is involved in migration of human monocytes and is regulated through their interaction with fibronectin or endothelium. Blood (2005) 1.40
Caveolae are a novel pathway for membrane-type 1 matrix metalloproteinase traffic in human endothelial cells. Mol Biol Cell (2003) 1.39
Cyclooxygenase-2: a therapeutic target in angiogenesis. Trends Mol Med (2003) 1.38
Stromal cell-derived factor-1alpha promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities. Cancer Res (2004) 1.38
Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. Immunity (2010) 1.35
Inhibitors of the calcineurin/NFAT pathway. Curr Med Chem (2004) 1.33
Blockade of NFAT activation by the second calcineurin binding site. J Biol Chem (2006) 1.24
Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism. J Biol Chem (2002) 1.15
MT1-MMP: universal or particular player in angiogenesis? Cancer Metastasis Rev (2006) 1.15
The up-regulation of human caspase-8 by interferon-gamma in breast tumor cells requires the induction and action of the transcription factor interferon regulatory factor-1. J Biol Chem (2004) 1.13
Retinoid X receptor alpha controls innate inflammatory responses through the up-regulation of chemokine expression. Proc Natl Acad Sci U S A (2010) 1.13
Complex pattern of membrane type 1 matrix metalloproteinase shedding. Regulation by autocatalytic cells surface inactivation of active enzyme. J Biol Chem (2002) 1.12
Prostanoid signal transduction and gene expression in the endothelium: role in cardiovascular diseases. Cardiovasc Res (2006) 1.08
Membrane type 1-matrix metalloproteinase is regulated by chemokines monocyte-chemoattractant protein-1/ccl2 and interleukin-8/CXCL8 in endothelial cells during angiogenesis. J Biol Chem (2004) 1.07
Cux-1 and Cux-2 control the development of Reelin expressing cortical interneurons. Dev Neurobiol (2008) 1.07
Statistical model to analyze quantitative proteomics data obtained by 18O/16O labeling and linear ion trap mass spectrometry: application to the study of vascular endothelial growth factor-induced angiogenesis in endothelial cells. Mol Cell Proteomics (2009) 1.06
MT1-MMP collagenolytic activity is regulated through association with tetraspanin CD151 in primary endothelial cells. Blood (2008) 1.05
General statistical framework for quantitative proteomics by stable isotope labeling. J Proteome Res (2014) 1.04
A robust method for quantitative high-throughput analysis of proteomes by 18O labeling. Mol Cell Proteomics (2010) 1.03
Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis. J Biol Chem (2008) 1.01
Depolarization of neural cells induces transcription of the Down syndrome critical region 1 isoform 4 via a calcineurin/nuclear factor of activated T cells-dependent pathway. J Biol Chem (2005) 1.01
MT1-MMP and integrins: Hand-to-hand in cell communication. Biofactors (2010) 1.01
NFATc3 regulates the transcription of genes involved in T-cell activation and angiogenesis. Blood (2011) 1.01
c-Jun N-terminal kinase (JNK) positively regulates NFATc2 transactivation through phosphorylation within the N-terminal regulatory domain. J Biol Chem (2005) 0.99
A cutaneous gene therapy approach to treat infection through keratinocyte-targeted overexpression of antimicrobial peptides. FASEB J (2004) 0.98
Calcium/calcineurin signaling in primary cortical astrocyte cultures: Rcan1-4 and cyclooxygenase-2 as NFAT target genes. Glia (2008) 0.97
The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators. Proc Natl Acad Sci U S A (2009) 0.94
COX-2 limits prostanoid production in activated HUVECs and is a source of PGH2 for transcellular metabolism to PGE2 by tumor cells. Arterioscler Thromb Vasc Biol (2009) 0.94
High-sensitivity analysis of specific peptides in complex samples by selected MS/MS ion monitoring and linear ion trap mass spectrometry: application to biological studies. J Mass Spectrom (2007) 0.93
Prostanoids in tumor angiogenesis: therapeutic intervention beyond COX-2. Trends Mol Med (2012) 0.93
Modeling normal and pathological processes through skin tissue engineering. Mol Carcinog (2007) 0.92
Role of metalloproteinases MMP-9 and MT1-MMP in CXCL12-promoted myeloma cell invasion across basement membranes. J Pathol (2006) 0.91
Functional interplay between endothelial nitric oxide synthase and membrane type 1 matrix metalloproteinase in migrating endothelial cells. Blood (2007) 0.91
Regulator of calcineurin 1 mediates pathological vascular wall remodeling. J Exp Med (2011) 0.90
The protease MT1-MMP drives a combinatorial proteolytic program in activated endothelial cells. FASEB J (2012) 0.90
Hepatocyte growth factor activates endothelial proangiogenic mechanisms relevant in chronic hepatitis C-associated neoangiogenesis. J Hepatol (2003) 0.90
The linker region joining the catalytic and the regulatory domains of CnA is essential for binding to NFAT. J Biol Chem (2005) 0.89
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) decoy receptor TRAIL-R3 is up-regulated by p53 in breast tumor cells through a mechanism involving an intronic p53-binding site. J Biol Chem (2003) 0.88
Calcium-dependent expression of TNF-alpha in neural cells is mediated by the calcineurin/NFAT pathway. Mol Cell Neurosci (2006) 0.87
Regulator of calcineurin 1 (Rcan1) has a protective role in brain ischemia/reperfusion injury. J Neuroinflammation (2012) 0.84
Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling. J Clin Invest (2015) 0.84
Quantitative in-depth analysis of the dynamic secretome of activated Jurkat T-cells. J Proteomics (2011) 0.83
Systematic characterization of phosphorylation sites in NFATc2 by linear ion trap mass spectrometry. Proteomics (2006) 0.82
Characterization of p53-mediated up-regulation of CD95 gene expression upon genotoxic treatment in human breast tumor cells. J Biol Chem (2003) 0.81
Mesenchymal niches of bone marrow in cancer. Clin Transl Oncol (2011) 0.81
A major role for RCAN1 in atherosclerosis progression. EMBO Mol Med (2013) 0.80
Site-specific cellular functions of MT1-MMP. Eur J Cell Biol (2012) 0.79
The hepatitis B virus X protein binds to and activates the NH(2)-terminal trans-activation domain of nuclear factor of activated T cells-1. Virology (2002) 0.78
MT1-MMP: A novel component of the macrophage cell fusion machinery. Commun Integr Biol (2010) 0.77
Transcription initiation sites and promoter structure of the human TRAIL-R3 gene. FEBS Lett (2002) 0.77
Combination of single-photon emission computed tomography and magnetic resonance imaging to track 111in-oxine-labeled human mesenchymal stem cells in neuroblastoma-bearing mice. Mol Imaging (2014) 0.76
Transcriptional regulation of the TRAIL-R3 gene. Vitam Horm (2004) 0.76
Madrid center not quite in limbo. Science (2005) 0.75
Enrichment of neural-related genes in human mesenchymal stem cells from neuroblastoma patients. Int J Mol Med (2012) 0.75