Published in J Biol Chem on January 25, 2005
Streptococcal viability and diminished stress tolerance in mutants lacking the signal recognition particle pathway or YidC2. Proc Natl Acad Sci U S A (2005) 1.50
A YidC-like Protein in the Archaeal Plasma Membrane. Structure (2015) 1.44
A dynamic cpSRP43-Albino3 interaction mediates translocase regulation of chloroplast signal recognition particle (cpSRP)-targeting components. J Biol Chem (2010) 1.15
Roles of Oxa1-related inner-membrane translocases in assembly of respiratory chain complexes. Biochim Biophys Acta (2008) 1.13
Efficient production of membrane-integrated and detergent-soluble G protein-coupled receptors in Escherichia coli. Protein Sci (2008) 1.08
The ins and outs of Mycobacterium tuberculosis protein export. Tuberculosis (Edinb) (2011) 1.06
Functional overlap but lack of complete cross-complementation of Streptococcus mutans and Escherichia coli YidC orthologs. J Bacteriol (2008) 0.95
Promiscuous targeting of polytopic membrane proteins to SecYEG or YidC by the Escherichia coli signal recognition particle. Mol Biol Cell (2011) 0.95
Isolation of cold-sensitive yidC mutants provides insights into the substrate profile of the YidC insertase and the importance of transmembrane 3 in YidC function. J Bacteriol (2007) 0.89
Secretome of obligate intracellular Rickettsia. FEMS Microbiol Rev (2014) 0.89
The role of the strictly conserved positively charged residue differs among the Gram-positive, Gram-negative, and chloroplast YidC homologs. J Biol Chem (2014) 0.86
Unbalanced charge distribution as a determinant for dependence of a subset of Escherichia coli membrane proteins on the membrane insertase YidC. MBio (2011) 0.85
YidC is involved in the biogenesis of the secreted autotransporter hemoglobin protease. J Biol Chem (2010) 0.85
Interaction of Streptococcus mutans YidC1 and YidC2 with translating and nontranslating ribosomes. J Bacteriol (2013) 0.81
YidC protein, a molecular chaperone for LacY protein folding via the SecYEG protein machinery. J Biol Chem (2013) 0.81
Rational design of a fusion partner for membrane protein expression in E. coli. Protein Sci (2009) 0.78
YidC/Alb3/Oxa1 Family of Insertases. J Biol Chem (2015) 0.78
YidC assists the stepwise and stochastic folding of membrane proteins. Nat Chem Biol (2016) 0.76
Arabidopsis thaliana Oxa proteins locate to mitochondria and fulfill essential roles during embryo development. Planta (2012) 0.76
Structure and mechanism of the lactose permease of Escherichia coli. Science (2003) 10.57
Translocation of proteins into mitochondria. Annu Rev Biochem (2007) 7.53
Type VII secretion--mycobacteria show the way. Nat Rev Microbiol (2007) 4.45
A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell (2005) 4.41
Lessons from lactose permease. Annu Rev Biophys Biomol Struct (2006) 3.69
Evolutionary conservation of biogenesis of beta-barrel membrane proteins. Nature (2003) 2.98
Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY. EMBO J (2006) 2.92
Structural determination of wild-type lactose permease. Proc Natl Acad Sci U S A (2007) 2.83
Sugar binding induces an outward facing conformation of LacY. Proc Natl Acad Sci U S A (2007) 2.66
Single-molecule FRET reveals sugar-induced conformational dynamics in LacY. Proc Natl Acad Sci U S A (2007) 2.24
Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia. Am J Hum Genet (2008) 2.21
Delivering proteins for export from the cytosol. Nat Rev Mol Cell Biol (2009) 2.00
Disulfide formation in the ER and mitochondria: two solutions to a common process. Science (2009) 1.97
A specific secretion system mediates PPE41 transport in pathogenic mycobacteria. Mol Microbiol (2006) 1.97
Ribosome binding to the Oxa1 complex facilitates co-translational protein insertion in mitochondria. EMBO J (2003) 1.79
Crystal structure of hemoglobin protease, a heme binding autotransporter protein from pathogenic Escherichia coli. J Biol Chem (2005) 1.76
Systematic analysis of the twin cx(9)c protein family. J Mol Biol (2009) 1.75
Manipulating phospholipids for crystallization of a membrane transport protein. Proc Natl Acad Sci U S A (2006) 1.71
Opening and closing of the periplasmic gate in lactose permease. Proc Natl Acad Sci U S A (2008) 1.68
The disulfide relay system of mitochondria is connected to the respiratory chain. J Cell Biol (2007) 1.66
A mutation in the lactose permease of Escherichia coli that decreases conformational flexibility and increases protein stability. Biochemistry (2003) 1.62
Lactose permease and the alternating access mechanism. Biochemistry (2011) 1.62
Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett (2005) 1.59
Binding affinity of lactose permease is not altered by the H+ electrochemical gradient. Proc Natl Acad Sci U S A (2004) 1.58
Autotransporter β-domains have a specific function in protein secretion beyond outer-membrane targeting. J Mol Biol (2011) 1.57
Limited tolerance towards folded elements during secretion of the autotransporter Hbp. Mol Microbiol (2007) 1.52
Mba1, a membrane-associated ribosome receptor in mitochondria. EMBO J (2006) 1.50
Aromatic stacking in the sugar binding site of the lactose permease. Biochemistry (2003) 1.49
Redox regulation of peptide receptivity of major histocompatibility complex class I molecules by ERp57 and tapasin. Nat Immunol (2007) 1.48
Interhelical packing modulates conformational flexibility in the lactose permease of Escherichia coli. Biochemistry (2005) 1.47
Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1. EMBO J (2007) 1.46
Energetics of ligand-induced conformational flexibility in the lactose permease of Escherichia coli. J Biol Chem (2006) 1.46
Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on the Escherichia coli ribosome. J Cell Biol (2003) 1.45
Role of YidC in folding of polytopic membrane proteins. J Cell Biol (2004) 1.43
Lactose permease as a paradigm for membrane transport proteins (Review). Mol Membr Biol (2004) 1.43
A novel role of the C-terminus of b 0,+ AT in the ER-Golgi trafficking of the rBAT-b 0,+ AT heterodimeric amino acid transporter. Biochem J (2009) 1.41
Mitochondrial disulfide bond formation is driven by intersubunit electron transfer in Erv1 and proofread by glutathione. Mol Cell (2010) 1.38
The lactose permease of Escherichia coli: overall structure, the sugar-binding site and the alternating access model for transport. FEBS Lett (2003) 1.36
Exploiting luminescence spectroscopy to elucidate the interaction between sugar and a tryptophan residue in the lactose permease of Escherichia coli. Proc Natl Acad Sci U S A (2003) 1.36
Structural conservation in the major facilitator superfamily as revealed by comparative modeling. Protein Sci (2004) 1.36
General secretion signal for the mycobacterial type VII secretion pathway. Proc Natl Acad Sci U S A (2012) 1.34
The Bam (Omp85) complex is involved in secretion of the autotransporter haemoglobin protease. Microbiology (2009) 1.34
The Cys154-->Gly mutation in LacY causes constitutive opening of the hydrophilic periplasmic pathway. J Mol Biol (2008) 1.33
Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition. Proc Natl Acad Sci U S A (2011) 1.33
Direct sugar binding to LacY measured by resonance energy transfer. Biochemistry (2006) 1.32
Probing of the rates of alternating access in LacY with Trp fluorescence. Proc Natl Acad Sci U S A (2009) 1.31
Composition of the type VII secretion system membrane complex. Mol Microbiol (2012) 1.29
Evolution of mitochondrial oxa proteins from bacterial YidC. Inherited and acquired functions of a conserved protein insertion machinery. J Biol Chem (2005) 1.28
An approach to membrane protein structure without crystals. Proc Natl Acad Sci U S A (2002) 1.28
Binding of hydrophobic D-galactopyranosides to the lactose permease of Escherichia coli. Biochemistry (2002) 1.28
Signal recognition particle (SRP)-mediated targeting and Sec-dependent translocation of an extracellular Escherichia coli protein. J Biol Chem (2002) 1.28
Site-directed alkylation of LacY: effect of the proton electrochemical gradient. J Mol Biol (2007) 1.28
Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway. J Biol Chem (2011) 1.27
Electrophysiological characterization of LacY. Proc Natl Acad Sci U S A (2009) 1.26
Evolutionary mix-and-match with MFS transporters. Proc Natl Acad Sci U S A (2013) 1.26
Protonation and sugar binding to LacY. Proc Natl Acad Sci U S A (2008) 1.25
Structure of sugar-bound LacY. Proc Natl Acad Sci U S A (2014) 1.23
Surface-exposed positions in the transmembrane helices of the lactose permease of Escherichia coli determined by intermolecular thiol cross-linking. Proc Natl Acad Sci U S A (2002) 1.22
Structural comparison of lactose permease and the glycerol-3-phosphate antiporter: members of the major facilitator superfamily. Curr Opin Struct Biol (2004) 1.22
The Oxa1 protein forms a homooligomeric complex and is an essential part of the mitochondrial export translocase in Neurospora crassa. J Biol Chem (2002) 1.21
Inhibition of L-type amino acid transporter 1 has antitumor activity in non-small cell lung cancer. Anticancer Res (2010) 1.20
Co-translational membrane insertion of mitochondrially encoded proteins. Biochim Biophys Acta (2009) 1.20
Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP). Hepatology (2014) 1.19
Residues in the H+ translocation site define the pKa for sugar binding to LacY. Biochemistry (2009) 1.17
SecB is a bona fide generalized chaperone in Escherichia coli. Proc Natl Acad Sci U S A (2004) 1.16
Elucidation of substrate binding interactions in a membrane transport protein by mass spectrometry. EMBO J (2003) 1.16
Escherichia coli hemoglobin protease autotransporter contributes to synergistic abscess formation and heme-dependent growth of Bacteroides fragilis. Infect Immun (2002) 1.16
Tim17p regulates the twin pore structure and voltage gating of the mitochondrial protein import complex TIM23. J Biol Chem (2006) 1.15
Site-directed alkylation of cysteine to test solvent accessibility of membrane proteins. Nat Protoc (2007) 1.15
Atp10p assists assembly of Atp6p into the F0 unit of the yeast mitochondrial ATPase. J Biol Chem (2004) 1.13
Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly. J Cell Biol (2011) 1.12
Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae. Mol Biol Cell (2003) 1.12
Sugar recognition by the lactose permease of Escherichia coli. J Biol Chem (2004) 1.12
F(1)F(0) ATP synthase subunit c is targeted by the SRP to YidC in the E. coli inner membrane. FEBS Lett (2004) 1.12
Import of small Tim proteins into the mitochondrial intermembrane space. EMBO J (2003) 1.12
Intermolecular thiol cross-linking via loops in the lactose permease of Escherichia coli. Proc Natl Acad Sci U S A (2003) 1.11
Sugar binding induces the same global conformational change in purified LacY as in the native bacterial membrane. Proc Natl Acad Sci U S A (2010) 1.11
Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. J Biol Chem (2010) 1.11
Sequence alignment and homology threading reveals prokaryotic and eukaryotic proteins similar to lactose permease. J Mol Biol (2006) 1.09
Targeting, insertion, and localization of Escherichia coli YidC. J Biol Chem (2002) 1.08
Mrpl36 is important for generation of assembly competent proteins during mitochondrial translation. Mol Biol Cell (2009) 1.08
Delineating electrogenic reactions during lactose/H+ symport. Biochemistry (2010) 1.08
System L amino acid transporter inhibitor enhances anti-tumor activity of cisplatin in a head and neck squamous cell carcinoma cell line. Cancer Lett (2008) 1.08
Versatility of inner membrane protein biogenesis in Escherichia coli. Mol Microbiol (2003) 1.07
The sulfhydryl oxidase Erv1 is a substrate of the Mia40-dependent protein translocation pathway. FEBS Lett (2007) 1.07
Biogenesis of MalF and the MalFGK(2) maltose transport complex in Escherichia coli requires YidC. J Biol Chem (2008) 1.07
Apo-intermediate in the transport cycle of lactose permease (LacY). Proc Natl Acad Sci U S A (2012) 1.07