|
1
|
Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat.
|
Proc Natl Acad Sci U S A
|
2009
|
2.14
|
|
2
|
Age-dependent declines in proteasome activity in the heart.
|
Arch Biochem Biophys
|
2002
|
1.52
|
|
3
|
Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.
|
J Biol Chem
|
2003
|
1.51
|
|
4
|
Cystathionine beta synthase deficiency promotes oxidative stress, fibrosis, and steatosis in mice liver.
|
Gastroenterology
|
2005
|
1.42
|
|
5
|
Impairment of proteasome structure and function in aging.
|
Int J Biochem Cell Biol
|
2002
|
1.40
|
|
6
|
Subcellular localization of methionine sulphoxide reductase A (MsrA): evidence for mitochondrial and cytosolic isoforms in rat liver cells.
|
Biochem J
|
2003
|
1.32
|
|
7
|
Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.
|
J Neurochem
|
2003
|
1.32
|
|
8
|
Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway.
|
J Cell Sci
|
2005
|
1.26
|
|
9
|
Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes.
|
Arch Biochem Biophys
|
2006
|
1.20
|
|
10
|
Mitochondrial protein oxidation and degradation in response to oxidative stress and aging.
|
Exp Gerontol
|
2006
|
1.20
|
|
11
|
Proteasome function in aging and oxidative stress: implications in protein maintenance failure.
|
Antioxid Redox Signal
|
2006
|
1.20
|
|
12
|
Oxidized mitochondrial protein degradation and repair in aging and oxidative stress.
|
Antioxid Redox Signal
|
2010
|
1.19
|
|
13
|
Methionine sulfoxide reductases: relevance to aging and protection against oxidative stress.
|
Ann N Y Acad Sci
|
2006
|
1.15
|
|
14
|
Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage.
|
J Biol Chem
|
2008
|
1.10
|
|
15
|
Proteolysis, free radicals, and aging.
|
Free Radic Biol Med
|
2002
|
1.09
|
|
16
|
Protein modification and replicative senescence of WI-38 human embryonic fibroblasts.
|
Aging Cell
|
2010
|
1.06
|
|
17
|
Towards the control of intracellular protein turnover: mitochondrial Lon protease inhibitors versus proteasome inhibitors.
|
Biochimie
|
2007
|
1.06
|
|
18
|
Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha.
|
Mol Cell Biol
|
2003
|
1.04
|
|
19
|
Protein maintenance in aging and replicative senescence: a role for the peptide methionine sulfoxide reductases.
|
Biochim Biophys Acta
|
2005
|
1.03
|
|
20
|
Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins.
|
FEBS J
|
2008
|
1.01
|
|
21
|
Protein oxidative modifications and replicative senescence of WI-38 human embryonic fibroblasts.
|
Ann N Y Acad Sci
|
2007
|
1.01
|
|
22
|
Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix.
|
Eur J Biochem
|
2003
|
1.00
|
|
23
|
Muscle creatine kinase deficiency triggers both actin depolymerization and desmin disorganization by advanced glycation end products in dilated cardiomyopathy.
|
J Biol Chem
|
2011
|
0.96
|
|
24
|
Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome.
|
Free Radic Biol Med
|
2012
|
0.96
|
|
25
|
Characterization and role of protozoan parasite proteasomes.
|
Trends Parasitol
|
2003
|
0.96
|
|
26
|
Maintenance of proteins and aging: the role of oxidized protein repair.
|
Free Radic Res
|
2006
|
0.96
|
|
27
|
Identification of novel oxidized protein substrates and physiological partners of the mitochondrial ATP-dependent Lon-like protease Pim1.
|
J Biol Chem
|
2010
|
0.95
|
|
28
|
Essential role of methionine residues in calmodulin binding to Bordetella pertussis adenylate cyclase, as probed by selective oxidation and repair by the peptide methionine sulfoxide reductases.
|
J Biol Chem
|
2004
|
0.95
|
|
29
|
Overexpression of MsrA protects WI-38 SV40 human fibroblasts against H2O2-mediated oxidative stress.
|
Free Radic Biol Med
|
2005
|
0.95
|
|
30
|
Impact of ageing on proteasome structure and function in human lymphocytes.
|
Int J Biochem Cell Biol
|
2003
|
0.95
|
|
31
|
Age-dependent protein modifications and declining proteasome activity in the human lens.
|
Arch Biochem Biophys
|
2004
|
0.95
|
|
32
|
Repeated exposures to UVB induce differentiation rather than senescence of human keratinocytes lacking p16(INK-4A).
|
Biogerontology
|
2009
|
0.94
|
|
33
|
Protein oxidative damage at the crossroads of cellular senescence, aging, and age-related diseases.
|
Oxid Med Cell Longev
|
2012
|
0.93
|
|
34
|
Proteomic quantification and identification of carbonylated proteins upon oxidative stress and during cellular aging.
|
J Proteomics
|
2013
|
0.93
|
|
35
|
Enzymatic reactions involved in the repair of oxidized proteins.
|
Exp Gerontol
|
2004
|
0.93
|
|
36
|
Impairment of proteasome function upon UVA- and UVB-irradiation of human keratinocytes.
|
Free Radic Biol Med
|
2002
|
0.91
|
|
37
|
Regulation of selenoproteins and methionine sulfoxide reductases A and B1 by age, calorie restriction, and dietary selenium in mice.
|
Antioxid Redox Signal
|
2010
|
0.91
|
|
38
|
Oxidative stress-induced proteome alterations target different cellular pathways in human myoblasts.
|
Free Radic Biol Med
|
2011
|
0.91
|
|
39
|
A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms.
|
Biol Chem
|
2006
|
0.91
|
|
40
|
Age-related impairment of mitochondrial matrix aconitase and ATP-stimulated protease in rat liver and heart.
|
Eur J Biochem
|
2004
|
0.90
|
|
41
|
The peptide methionine sulfoxide reductases, MsrA and MsrB (hCBS-1), are downregulated during replicative senescence of human WI-38 fibroblasts.
|
FEBS Lett
|
2004
|
0.89
|
|
42
|
The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression.
|
J Biol Chem
|
2009
|
0.87
|
|
43
|
The ubiquitin-proteasome system at the crossroads of stress-response and ageing pathways: a handle for skin care?
|
Ageing Res Rev
|
2005
|
0.87
|
|
44
|
Impairment of methionine sulfoxide reductase during UV irradiation and photoaging.
|
Exp Gerontol
|
2007
|
0.87
|
|
45
|
Alterations in mitochondrial and cytosolic methionine sulfoxide reductase activity during cardiac ischemia and reperfusion.
|
Exp Gerontol
|
2006
|
0.86
|
|
46
|
Oxidative proteome modifications target specific cellular pathways during oxidative stress, cellular senescence and aging.
|
Exp Gerontol
|
2012
|
0.85
|
|
47
|
Overexpression of methionine sulfoxide reductases A and B2 protects MOLT-4 cells against zinc-induced oxidative stress.
|
Antioxid Redox Signal
|
2009
|
0.85
|
|
48
|
Expression and modification proteomics during skeletal muscle ageing.
|
Biogerontology
|
2013
|
0.85
|
|
49
|
Age-related increase of protein glycation in peripheral blood lymphocytes is restricted to preferential target proteins.
|
Exp Gerontol
|
2002
|
0.85
|
|
50
|
Changes of the proteasomal system during the aging process.
|
Prog Mol Biol Transl Sci
|
2012
|
0.85
|
|
51
|
Algae extract-mediated stimulation and protection of proteasome activity within human keratinocytes exposed to UVA and UVB irradiation.
|
Antioxid Redox Signal
|
2006
|
0.84
|
|
52
|
Cellular senescence in human keratinocytes: unchanged proteolytic capacity and increased protein load.
|
Exp Gerontol
|
2003
|
0.82
|
|
53
|
Impact of hydrogen peroxide on the activity, structure, and conformational stability of the oxidized protein repair enzyme methionine sulfoxide reductase A.
|
J Mol Biol
|
2009
|
0.81
|
|
54
|
Aging of the dopaminergic system and motor behavior in mice intoxicated with the parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
|
J Neurochem
|
2012
|
0.81
|
|
55
|
Glycation damage targets glutamate dehydrogenase in the rat liver mitochondrial matrix during aging.
|
FEBS J
|
2007
|
0.81
|
|
56
|
Reduced oxygen tension results in reduced human T cell proliferation and increased intracellular oxidative damage and susceptibility to apoptosis upon activation.
|
Free Radic Biol Med
|
2009
|
0.80
|
|
57
|
Catalase, a target of glycation damage in rat liver mitochondria with aging.
|
Biochim Biophys Acta
|
2012
|
0.80
|
|
58
|
Proteasome and photoaging: the effects of UV irradiation.
|
Ann N Y Acad Sci
|
2007
|
0.79
|
|
59
|
Differential expression and glycative damage affect specific mitochondrial proteins with aging in rat liver.
|
Biochim Biophys Acta
|
2013
|
0.79
|
|
60
|
Oxidized SOD1 alters proteasome activities in vitro and in the cortex of SOD1 overexpressing mice.
|
FEBS Lett
|
2005
|
0.79
|
|
61
|
Increased level of glycoxidation product N(epsilon)-(carboxymethyl)lysine in rat serum and urine proteins with aging: link with glycoxidative damage accumulation in kidney.
|
Arch Biochem Biophys
|
2003
|
0.78
|
|
62
|
Proteome modulation in H9c2 cardiac cells by microRNAs miR-378 and miR-378.
|
Mol Cell Proteomics
|
2013
|
0.78
|
|
63
|
Advanced glycation endproducts induce photocrosslinking and oxidation of bovine lens proteins through type-I mechanism.
|
Photochem Photobiol
|
2008
|
0.78
|
|
64
|
The second international conference "genetics of aging and longevity".
|
Aging (Albany NY)
|
2012
|
0.77
|
|
65
|
Evidence of preferential protein targets for age-related modifications in peripheral blood lymphocytes.
|
Ann N Y Acad Sci
|
2004
|
0.76
|
|
66
|
Prevention of dicarbonyl-mediated advanced glycation by glyoxalases: implication in skin aging.
|
Biochem Soc Trans
|
2014
|
0.76
|
|
67
|
Proteome alteration in oxidative stress-sensitive methionine sulfoxide reductase-silenced HEK293 cells.
|
Free Radic Biol Med
|
2013
|
0.76
|
|
68
|
Simultaneous chemical and photochemical protein crosslinking induced by irradiation of eye lens proteins in the presence of ascorbate: the photosensitizing role of an UVA-visible-absorbing decomposition product of vitamin C.
|
Photochem Photobiol Sci
|
2010
|
0.76
|
|
69
|
Dietary fatty acids and oxidative stress in the heart mitochondria.
|
Mitochondrion
|
2010
|
0.76
|
|
70
|
Algae extract protection effect on oxidized protein level in human stratum corneum.
|
Ann N Y Acad Sci
|
2004
|
0.76
|
|
71
|
Zinc supplementation in the elderly subjects: effect on oxidized protein degradation and repair systems in peripheral blood lymphocytes.
|
Exp Gerontol
|
2007
|
0.76
|
|
72
|
Proteasome: a new target of UV radiations.
|
Eur J Dermatol
|
2002
|
0.75
|
|
73
|
Autosensitized oxidation of glycated bovine lens proteins irradiated with UVA-visible light at low oxygen concentration.
|
Photochem Photobiol Sci
|
2008
|
0.75
|
|
74
|
Are expanded polyglutamine proteins a proteasome substrate?
|
Rejuvenation Res
|
2004
|
0.75
|
|
75
|
Endogenous C-terminal fragments of beta-amyloid precursor protein from Xenopus laevis skin exudate.
|
Comp Biochem Physiol B Biochem Mol Biol
|
2006
|
0.75
|
|
76
|
Clearance of genetic variants of amyloid β peptide by neuronal and non-neuronal cells.
|
Protein Pept Lett
|
2013
|
0.75
|
|
77
|
Photosensitized reactions mediated by the major chromophore arising from glucose decomposition, result in oxidation and cross-linking of lens proteins and activation of the proteasome.
|
Biochim Biophys Acta
|
2011
|
0.75
|