Robert Nitsch

Author PubWeight™ 112.45‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 2008 7.35
2 Regulation of miRNA expression during neural cell specification. Eur J Neurosci 2005 5.27
3 Post-transcriptional regulation of the let-7 microRNA during neural cell specification. FASEB J 2006 4.34
4 OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling. Nat Neurosci 2010 3.21
5 An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nat Neurosci 2012 2.90
6 Sirt1 contributes critically to the redox-dependent fate of neural progenitors. Nat Cell Biol 2008 2.71
7 The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. Neuron 2006 2.55
8 The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2. Nat Cell Biol 2009 2.12
9 Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation. FASEB J 2005 2.04
10 Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL. Neuron 2005 2.01
11 A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting. Nat Neurosci 2003 1.95
12 Migration of monocytes after intracerebral injection at entorhinal cortex lesion site. J Leukoc Biol 2012 1.93
13 A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS. J Neurosci 2008 1.85
14 Toll-like receptor 2 mediates CNS injury in focal cerebral ischemia. J Neuroimmunol 2007 1.85
15 A mechanism for neurodegeneration induced by group B streptococci through activation of the TLR2/MyD88 pathway in microglia. J Immunol 2006 1.76
16 Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline. Proc Natl Acad Sci U S A 2010 1.76
17 CXCR3-dependent microglial recruitment is essential for dendrite loss after brain lesion. J Neurosci 2004 1.57
18 Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease. J Neurochem 2003 1.48
19 Treatment of relapsing paralysis in experimental encephalomyelitis by targeting Th1 cells through atorvastatin. J Exp Med 2003 1.47
20 The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1. Eur J Neurosci 2011 1.46
21 An impaired neocortical Ih is associated with enhanced excitability and absence epilepsy. Eur J Neurosci 2004 1.43
22 Selenium and brain function: a poorly recognized liaison. Brain Res Brain Res Rev 2004 1.42
23 Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal. Proc Natl Acad Sci U S A 2012 1.36
24 Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis. Ann Neurol 2009 1.32
25 The role of T helper cells in neuroprotection and regeneration. J Neuroimmunol 2007 1.30
26 Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell 2009 1.29
27 Activation of microglial poly(ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage. J Exp Med 2003 1.25
28 Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury. Biochem Pharmacol 2002 1.21
29 Multiple sclerosis - candidate mechanisms underlying CNS atrophy. Trends Neurosci 2010 1.19
30 Selenium deficiency increases susceptibility to glutamate-induced excitotoxicity. FASEB J 2002 1.16
31 Differential immune cell dynamics in the CNS cause CD4+ T cell compartmentalization. Brain 2009 1.11
32 Regulatory T cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO. J Cereb Blood Flow Metab 2012 1.11
33 Plasticity-related gene 5 (PRG5) induces filopodia and neurite growth and impedes lysophosphatidic acid- and nogo-A-mediated axonal retraction. Mol Biol Cell 2009 1.09
34 Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain. J Neurosci 2002 1.09
35 miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling. EMBO J 2012 1.07
36 Neuronal damage in brain inflammation. Arch Neurol 2007 1.07
37 Circulating monocytic cells infiltrate layers of anterograde axonal degeneration where they transform into microglia. FASEB J 2005 1.01
38 Molecular cloning and expression regulation of PRG-3, a new member of the plasticity-related gene family. Eur J Neurosci 2004 1.00
39 Ongoing expression of Nkx2.1 in the postnatal mouse forebrain: potential for understanding NKX2.1 haploinsufficiency in humans? Brain Res 2009 0.99
40 The cytokine/neurotrophin axis in peripheral axon outgrowth. Eur J Neurosci 2006 0.99
41 MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4. J Clin Invest 2015 0.97
42 TLR2 and caspase-8 are essential for group B Streptococcus-induced apoptosis in microglia. J Immunol 2007 0.97
43 In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics. Proteomics 2014 0.97
44 Impact of HMG-CoA reductase inhibition on brain pathology. Trends Pharmacol Sci 2007 0.96
45 Neuroprotection by T-cells depends on their subtype and activation state. J Neuroimmunol 2002 0.96
46 CNS-irrelevant T-cells enter the brain, cause blood-brain barrier disruption but no glial pathology. Eur J Neurosci 2007 0.96
47 Bone marrow-derived cells expressing green fluorescent protein under the control of the glial fibrillary acidic protein promoter do not differentiate into astrocytes in vitro and in vivo. J Neurosci 2003 0.96
48 IDO (indolamine 2,3-dioxygenase) expression and function in the CNS. Adv Exp Med Biol 2003 0.96
49 The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity. EMBO J 2007 0.95
50 Analysis of lipid experiments (ALEX): a software framework for analysis of high-resolution shotgun lipidomics data. PLoS One 2013 0.95
51 Hyperpolarization-activated cation currents in human epileptogenic neocortex. Epilepsia 2009 0.94
52 Comparative analysis of uncoupling protein 4 distribution in various tissues under physiological conditions and during development. Biochim Biophys Acta 2009 0.94
53 Expression of Toll-like receptors in the developing brain. PLoS One 2012 0.93
54 Identification of neuronal cell death in a model of degeneration in the hippocampus. Brain Res Brain Res Protoc 2003 0.93
55 Absence of IL-1β positively affects neurological outcome, lesion development and axonal plasticity after spinal cord injury. J Neuroinflammation 2013 0.92
56 Astrocytes protect the CNS: antigen-specific T helper cell responses are inhibited by astrocyte-induced upregulation of CTLA-4 (CD152). J Mol Med (Berl) 2004 0.90
57 Plasticity-related genes (PRGs/LRPs): a brain-specific class of lysophospholipid-modifying proteins. Biochim Biophys Acta 2008 0.89
58 Green-fluorescent-protein-expressing mice as models for the study of axonal growth and regeneration in vitro. Brain Res Rev 2006 0.89
59 Modification of microglia function protects from lesion-induced neuronal alterations and promotes sprouting in the hippocampus. FASEB J 2003 0.89
60 Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. Gene 2002 0.89
61 Components of neuronal chloride transport in rat and human neocortex. J Physiol 2011 0.88
62 Entorhinal cortex lesion in the mouse induces transsynaptic death of perforant path target neurons. Brain Pathol 2004 0.87
63 Molecular analysis of Nogo expression in the hippocampus during development and following lesion and seizure. FASEB J 2003 0.86
64 The majority of brain mast cells in B10.PL mice is present in the hippocampal formation. Neurosci Lett 2005 0.85
65 Astrocyte-induced T cell elimination is CD95 ligand dependent. J Neuroimmunol 2002 0.84
66 MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4. J Clin Invest 2015 0.84
67 Macrophage/microglia activation factor expression is restricted to lesion-associated microglial cells after brain trauma. Glia 2006 0.82
68 Improved outcome of facial nerve repair in rats is associated with enhanced regenerative response of motoneurons and augmented neocortical plasticity. Eur J Neurosci 2006 0.82
69 Differential regulation of axon outgrowth and reinnervation by neurotrophin-3 and neurotrophin-4 in the hippocampal formation. Exp Brain Res 2010 0.82
70 Homeostatic regulation of NCAM polysialylation is critical for correct synaptic targeting. Cell Mol Life Sci 2011 0.82
71 Microglial activation milieu controls regulatory T cell responses. J Immunol 2013 0.81
72 Impaired function of GABA(B) receptors in tissues from pharmacoresistant epilepsy patients. Epilepsia 2009 0.81
73 Profiling of lipid species by normal-phase liquid chromatography, nanoelectrospray ionization, and ion trap-orbitrap mass spectrometry. Anal Biochem 2013 0.81
74 A tissue engineered heart valve implanted in a juvenile sheep model. Med Sci Monit 2003 0.81
75 Interleukin-1 beta and neurotrophin-3 synergistically promote neurite growth in vitro. J Neuroinflammation 2011 0.81
76 Identification of macrophage/microglia activation factor (MAF) associated with late endosomes/lysosomes in microglial cells. FEBS Lett 2004 0.80
77 Comparison of neuronal density and subfield sizes in the hippocampus of CD95L-deficient (gld), CD95-deficient (lpr) and nondeficient mice. Eur J Neurosci 2002 0.79
78 Santiago Ramón y Cajal's concept of neuronal plasticity: the ambiguity lives on. Trends Neurosci 2002 0.79
79 Tumor-necrosis-factor-related apoptosis-inducing-ligand (TRAIL)-mediated death of neurons in living human brain tissue is inhibited by flupirtine-maleate. J Neuroimmunol 2005 0.79
80 Elevation in type I interferons inhibits HCN1 and slows cortical neuronal oscillations. Cereb Cortex 2012 0.79
81 Impaired postnatal development of hippocampal neurons and axon projections in the Emx2-/- mutants. J Neurochem 2002 0.78
82 B56beta, a regulatory subunit of protein phosphatase 2A, interacts with CALEB/NGC and inhibits CALEB/NGC-mediated dendritic branching. FASEB J 2008 0.77
83 Production of neuroprotective NGF in astrocyte-T helper cell cocultures is upregulated following antigen recognition. J Neuroimmunol 2004 0.76
84 Tolerogenic effect of fiber tract injury: reduced EAE severity following entorhinal cortex lesion. Exp Brain Res 2006 0.75
85 Quantitative spatial analysis of the mouse brain lipidome by pressurized liquid extraction surface analysis. Anal Chem 2015 0.75
86 PRG-1 transcriptional regulation independent from Nex1/Math2-mediated activation. Cell Mol Life Sci 2011 0.75