Published in FASEB J on January 25, 2005
TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis. PLoS Med (2007) 2.62
Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair. Front Cell Neurosci (2013) 1.34
Microglial recruitment, activation, and proliferation in response to primary demyelination. Am J Pathol (2007) 1.31
Cellular inflammation in nonarteritic anterior ischemic optic neuropathy and its primate model. Arch Ophthalmol (2011) 1.05
Iron deposits in the chronically inflamed central nervous system and contributes to neurodegeneration. Cell Mol Life Sci (2013) 1.02
Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury. J Neuroinflammation (2012) 0.96
Differential role of CCR2 in the dynamics of microglia and perivascular macrophages during prion disease. Glia (2014) 0.95
Immune and behavioral consequences of microglial reactivity in the aged brain. Integr Comp Biol (2009) 0.95
Population control of resident and immigrant microglia by mitosis and apoptosis. Am J Pathol (2007) 0.92
Age-dependent microglial activation in immature brains after hypoxia- ischemia. CNS Neurol Disord Drug Targets (2013) 0.89
Differential effects of homotypic vs. heterotypic chronic stress regimens on microglial activation in the prefrontal cortex. Physiol Behav (2013) 0.88
Eradication of human immunodeficiency virus from brain reservoirs. J Neurovirol (2014) 0.84
Feasibility of cell therapy in multiple sclerosis: a systematic review of 83 studies. Int J Hematol Oncol Stem Cell Res (2013) 0.83
Phosphodiesterase-5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and Cognition. Mediators Inflamm (2015) 0.82
Migration of monocytes after intracerebral injection. Cell Adh Migr (2012) 0.78
Brain APCs including microglia are only differential and positional polymorphs. Ann Neurosci (2010) 0.76
Tolerogenic effect of fiber tract injury: reduced EAE severity following entorhinal cortex lesion. Exp Brain Res (2006) 0.75
A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol (2008) 7.35
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nat Neurosci (2007) 6.23
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. Nat Med (2002) 5.50
Regulation of miRNA expression during neural cell specification. Eur J Neurosci (2005) 5.27
Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nat Med (2005) 4.42
Post-transcriptional regulation of the let-7 microRNA during neural cell specification. FASEB J (2006) 4.34
Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med (2003) 3.89
Evidence for the efficacy of NXY-059 in experimental focal cerebral ischaemia is confounded by study quality. Stroke (2008) 3.87
Central nervous system injury-induced immune deficiency syndrome. Nat Rev Neurosci (2005) 3.45
Good laboratory practice: preventing introduction of bias at the bench. Stroke (2008) 3.27
OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling. Nat Neurosci (2010) 3.21
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration. Nat Neurosci (2011) 3.06
Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach. Stroke (2008) 2.98
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nat Neurosci (2012) 2.90
Sirt1 contributes critically to the redox-dependent fate of neural progenitors. Nat Cell Biol (2008) 2.71
CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system. Brain (2009) 2.59
The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. Neuron (2006) 2.55
Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition. Arterioscler Thromb Vasc Biol (2002) 2.54
Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial. Ann Intern Med (2014) 2.48
Preventive antibacterial therapy in acute ischemic stroke: a randomized controlled trial. PLoS One (2008) 2.39
Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J Neurosci (2011) 2.31
Improving outcome after stroke: overcoming the translational roadblock. Cerebrovasc Dis (2008) 2.26
Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase-dependent augmentation of neovascularization and cerebral blood flow. Circ Res (2006) 2.21
The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2. Nat Cell Biol (2009) 2.12
Sulfonylureas improve outcome in patients with type 2 diabetes and acute ischemic stroke. Stroke (2007) 2.10
Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage. Brain (2009) 2.06
Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model. J Neurosci (2002) 2.05
Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation. FASEB J (2005) 2.04
Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL. Neuron (2005) 2.01
Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent. Stroke (2002) 2.00
A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting. Nat Neurosci (2003) 1.95
Migration of monocytes after intracerebral injection at entorhinal cortex lesion site. J Leukoc Biol (2012) 1.93
Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain. Proc Natl Acad Sci U S A (2010) 1.91
A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS. J Neurosci (2008) 1.85
Toll-like receptor 2 mediates CNS injury in focal cerebral ischemia. J Neuroimmunol (2007) 1.85
Stroke and the immune system: from pathophysiology to new therapeutic strategies. Lancet Neurol (2011) 1.77
A mechanism for neurodegeneration induced by group B streptococci through activation of the TLR2/MyD88 pathway in microglia. J Immunol (2006) 1.76
Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline. Proc Natl Acad Sci U S A (2010) 1.76
Stroke research priorities for the next decade--A representative view of the European scientific community. Cerebrovasc Dis (2006) 1.75
Marrow-derived cells as vehicles for delivery of gene therapy to pulmonary epithelium. Am J Respir Cell Mol Biol (2002) 1.70
Mechanisms of stroke protection by physical activity. Ann Neurol (2003) 1.67
Hypoxia-induced stroke tolerance in the mouse is mediated by erythropoietin. Stroke (2003) 1.65
Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice. Brain (2006) 1.63
Estrogen increases bone marrow-derived endothelial progenitor cell production and diminishes neointima formation. Circulation (2003) 1.61
Pathophysiology of stroke: lessons from animal models. Metab Brain Dis (2004) 1.61
Women, hormones, and clinical trials: a beginning, not an end. J Appl Physiol (1985) (2005) 1.60
Role of glial cells in cerebral ischemia. Glia (2005) 1.58
Tickets to the brain: role of CCR2 and CX3CR1 in myeloid cell entry in the CNS. J Neuroimmunol (2010) 1.57
CXCR3-dependent microglial recruitment is essential for dendrite loss after brain lesion. J Neurosci (2004) 1.57
Angiotensin AT2 receptor protects against cerebral ischemia-induced neuronal injury. FASEB J (2005) 1.54
Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease. J Neurochem (2003) 1.48
Treatment of relapsing paralysis in experimental encephalomyelitis by targeting Th1 cells through atorvastatin. J Exp Med (2003) 1.47
Reprint: Good laboratory practice: preventing introduction of bias at the bench. J Cereb Blood Flow Metab (2008) 1.47
The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1. Eur J Neurosci (2011) 1.46
Desferrioxamine induces delayed tolerance against cerebral ischemia in vivo and in vitro. J Cereb Blood Flow Metab (2002) 1.44
An impaired neocortical Ih is associated with enhanced excitability and absence epilepsy. Eur J Neurosci (2004) 1.43
Cellular immunodepression preceding infectious complications after acute ischemic stroke in humans. Cerebrovasc Dis (2007) 1.42
Roller culture of free-floating retinal slices: a new system of organotypic cultures of adult rat retina. Ophthalmic Res (2006) 1.42
Selenium and brain function: a poorly recognized liaison. Brain Res Brain Res Rev (2004) 1.42
Neuroprotective role of astrocytes in cerebral ischemia: focus on ischemic preconditioning. Glia (2005) 1.40
Stroke propagates bacterial aspiration to pneumonia in a model of cerebral ischemia. Stroke (2006) 1.39
IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system. Brain (2011) 1.37
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal. Proc Natl Acad Sci U S A (2012) 1.36
Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in mice. Brain Res (2002) 1.36
Estrogen receptor alpha interacts with Galpha13 to drive actin remodeling and endothelial cell migration via the RhoA/Rho kinase/moesin pathway. Mol Endocrinol (2006) 1.35
Systematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and Metabolism. J Cereb Blood Flow Metab (2010) 1.35
Modeling stroke in mice - middle cerebral artery occlusion with the filament model. J Vis Exp (2011) 1.33
Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells. Proc Natl Acad Sci U S A (2002) 1.33
Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis. Ann Neurol (2009) 1.32
SUMO2/3 conjugation is an endogenous neuroprotective mechanism. J Cereb Blood Flow Metab (2011) 1.32
Body weight after stroke: lessons from the obesity paradox. Stroke (2011) 1.31
Endothelin-1 potently induces Leão's cortical spreading depression in vivo in the rat: a model for an endothelial trigger of migrainous aura? Brain (2002) 1.30
The role of T helper cells in neuroprotection and regeneration. J Neuroimmunol (2007) 1.30
T cells traffic from brain to cervical lymph nodes via the cribroid plate and the nasal mucosa. J Leukoc Biol (2006) 1.30
Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell (2009) 1.29
Activation of microglial poly(ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage. J Exp Med (2003) 1.25
Neurovascular coupling in rat brain operates independent of hemoglobin deoxygenation. J Cereb Blood Flow Metab (2009) 1.24
International, multicenter randomized preclinical trials in translational stroke research: it's time to act. J Cereb Blood Flow Metab (2012) 1.24
Genetic screening for Niemann-Pick disease type C in adults with neurological and psychiatric symptoms: findings from the ZOOM study. Hum Mol Genet (2013) 1.24
Serial analysis of gene expression identifies metallothionein-II as major neuroprotective gene in mouse focal cerebral ischemia. J Neurosci (2002) 1.22
Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase. J Clin Invest (2004) 1.22
Brain mitochondrial uncoupling protein 2 (UCP2): a protective stress signal in neuronal injury. Biochem Pharmacol (2002) 1.21
Preventive antibacterial treatment improves the general medical and neurological outcome in a mouse model of stroke. Stroke (2003) 1.21
Triptans reduce the inflammatory response in bacterial meningitis. J Cereb Blood Flow Metab (2002) 1.20
Isoflurane induced prolonged protection against cerebral ischemia in mice: a redox sensitive mechanism? Neuroreport (2002) 1.20
Multiple sclerosis - candidate mechanisms underlying CNS atrophy. Trends Neurosci (2010) 1.19
Postmenopausal hormone therapy: new questions and the case for new clinical trials. Menopause (2006) 1.18
Fighting publication bias: introducing the Negative Results section. J Cereb Blood Flow Metab (2010) 1.17