Charles O Elson

Author PubWeight™ 117.41‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 2006 25.91
2 Late developmental plasticity in the T helper 17 lineage. Immunity 2009 8.81
3 Anti-interleukin-12 antibody for active Crohn's disease. N Engl J Med 2004 7.93
4 Bacterial flagellin is a dominant antigen in Crohn disease. J Clin Invest 2004 5.39
5 The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science 2013 4.60
6 Reciprocal interactions of the intestinal microbiota and immune system. Nature 2012 4.42
7 Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease. Gastroenterology 2005 3.41
8 Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria. Nature 2013 3.21
9 A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota. Proc Natl Acad Sci U S A 2009 2.77
10 Serum immune responses predict rapid disease progression among children with Crohn's disease: immune responses predict disease progression. Am J Gastroenterol 2006 2.14
11 Acute gastrointestinal infection induces long-lived microbiota-specific T cell responses. Science 2012 2.01
12 Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis. J Exp Med 2010 1.86
13 Cdcs1, a major colitogenic locus in mice, regulates innate and adaptive immune response to enteric bacterial antigens. Gastroenterology 2005 1.81
14 The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin. Annu Rev Pathol 2012 1.80
15 Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells. J Immunol 2004 1.71
16 T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitis. J Exp Med 2002 1.69
17 TGF-beta promotes Th17 cell development through inhibition of SOCS3. J Immunol 2009 1.66
18 Molecular mechanism of lipopolysaccharide-induced SOCS-3 gene expression in macrophages and microglia. J Immunol 2007 1.58
19 Experimental inflammatory bowel disease: insights into the host-microbiota dialog. Immunity 2011 1.53
20 Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora. J Immunol 2002 1.49
21 Isolation of flagellated bacteria implicated in Crohn's disease. Inflamm Bowel Dis 2007 1.40
22 Th17 cells induce colitis and promote Th1 cell responses through IL-17 induction of innate IL-12 and IL-23 production. J Immunol 2011 1.39
23 Interleukin-12 converts Foxp3+ regulatory T cells to interferon-γ-producing Foxp3+ T cells that inhibit colitis. Gastroenterology 2011 1.35
24 Th17 cells upregulate polymeric Ig receptor and intestinal IgA and contribute to intestinal homeostasis. J Immunol 2012 1.34
25 Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations. Inflamm Bowel Dis 2007 1.33
26 Tight mucosal compartmentation of the murine immune response to antigens of the enteric microbiota. Gastroenterology 2006 1.29
27 Generation of mucosal dendritic cells from bone marrow reveals a critical role of retinoic acid. J Immunol 2010 1.29
28 Perspectives on mucosal vaccines: is mucosal tolerance a barrier? J Immunol 2007 1.28
29 A novel role for defensins in intestinal homeostasis: regulation of IL-1beta secretion. J Immunol 2007 1.23
30 Refined histopathologic scoring system improves power to detect colitis QTL in mice. Mamm Genome 2004 1.20
31 Fenofibrate represses interleukin-17 and interferon-gamma expression and improves colitis in interleukin-10-deficient mice. Gastroenterology 2007 1.18
32 Microbial induction of inflammatory bowel disease associated gene TL1A (TNFSF15) in antigen presenting cells. Eur J Immunol 2009 1.18
33 Microbiota downregulates dendritic cell expression of miR-10a, which targets IL-12/IL-23p40. J Immunol 2011 1.14
34 Regulation of gene expression in inflammatory bowel disease and correlation with IBD drugs: screening by DNA microarrays. Inflamm Bowel Dis 2004 1.09
35 ERK differentially regulates Th17- and Treg-cell development and contributes to the pathogenesis of colitis. Eur J Immunol 2013 1.04
36 Generation of antigen-specific, Foxp3-expressing CD4+ regulatory T cells by inhibition of APC proteosome function. J Immunol 2005 1.03
37 Altered microbiota associated with abnormal humoral immune responses to commensal organisms in enthesitis-related arthritis. Arthritis Res Ther 2014 1.02
38 Microbiota activation and regulation of innate and adaptive immunity. Immunol Rev 2014 0.98
39 Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease. Clin Transl Gastroenterol 2012 0.92
40 Downregulation of microRNA-107 in intestinal CD11c(+) myeloid cells in response to microbiota and proinflammatory cytokines increases IL-23p19 expression. Eur J Immunol 2014 0.91
41 Immune response versus mucosal tolerance to mucosally administered antigens. Vaccine 2005 0.91
42 Animal models of intestinal inflammation: ineffective communication between coalition members. Springer Semin Immunopathol 2005 0.91
43 Curcumin induces the tolerogenic dendritic cell that promotes differentiation of intestine-protective regulatory T cells. Eur J Immunol 2009 0.90
44 TGF-β converts Th1 cells into Th17 cells through stimulation of Runx1 expression. Eur J Immunol 2015 0.89
45 Enhanced CBir1-specific innate and adaptive immune responses in Crohn's disease. Inflamm Bowel Dis 2008 0.89
46 Probiotics and immune regulation of inflammatory bowel diseases. Curr Drug Targets Inflamm Allergy 2003 0.88
47 Treg cell-IgA axis in maintenance of host immune homeostasis with microbiota. Int Immunopharmacol 2010 0.86
48 Clostridium difficile carriage and serum antitoxin responses in children with inflammatory bowel disease. Inflamm Bowel Dis 2013 0.85
49 CCFA microbial-host interactions workshop: highlights and key observations. Inflamm Bowel Dis 2007 0.81
50 Oral tolerance in humans: failure to suppress an existing immune response by oral antigen administration. Ann N Y Acad Sci 2004 0.81
51 Microbiota: dual-faceted player in experimental colitis. Gut Microbes 2011 0.80
52 Regulation of Toll-like receptor 5 gene expression and function on mucosal dendritic cells. PLoS One 2012 0.80
53 From cheese to pharma: a designer probiotic for IBD. Clin Gastroenterol Hepatol 2006 0.80
54 Peyer's patches as the inductive site for IgA responses. J Immunol 2008 0.79