Published in Clin Exp Metastasis on January 01, 2004
Risk assessment, disease prevention and personalised treatments in breast cancer: is clinically qualified integrative approach in the horizon? EPMA J (2013) 1.17
Inhibitors of polyamine biosynthesis decrease the expression of the metalloproteases meprin alpha and MMP-7 in hormone-independent human breast cancer cells. Clin Exp Metastasis (2005) 0.95
Metastasis of hormone-independent breast cancer to lung and bone is decreased by alpha-difluoromethylornithine treatment. Breast Cancer Res (2005) 0.91
LPS-induced CCL2 expression and macrophage influx into the murine central nervous system is polyamine-dependent. Brain Behav Immun (2011) 0.85
Expression profiling and biochemical analysis suggest stress response as a potential mechanism inhibiting proliferation of polyamine-depleted cells. J Biol Chem (2012) 0.81
Effects of polyamine synthesis inhibitors on primary tumor features and metastatic capacity of human breast cancer cells. Clin Exp Metastasis (2005) 0.78
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell (1994) 9.73
A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc Natl Acad Sci U S A (1990) 5.26
Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1. Nat Med (2000) 5.05
Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis. Cancer Res (1994) 2.20
Plasma thrombospondin levels in patients with colorectal carcinoma. Cancer (1998) 1.57
Osteopontin induces increased invasiveness and plasminogen activator expression of human mammary epithelial cells. Oncogene (1999) 1.51
Contrasting expression of thrombospondin-1 and osteopontin correlates with absence or presence of metastatic phenotype in an isogenic model of spontaneous human breast cancer metastasis. Clin Cancer Res (2002) 1.45
Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice. Oncogene (2002) 1.27
Polyamine depletion arrests cell cycle and induces inhibitors p21(Waf1/Cip1), p27(Kip1), and p53 in IEC-6 cells. Am J Physiol (1999) 1.24
The role of osteopontin in breast cancer: clinical and experimental studies. J Mammary Gland Biol Neoplasia (2001) 1.24
Osteopontin-induced, integrin-dependent migration of human mammary epithelial cells involves activation of the hepatocyte growth factor receptor (Met). J Cell Biochem (2000) 1.24
Thrombospondin 1--a regulator of adenoma growth and carcinoma progression in the APC(Min/+) mouse model. Carcinogenesis (2003) 1.04
Recombinant GST-human osteopontin fusion protein is functional in RGD-dependent cell adhesion. J Cell Biochem (1994) 0.93
Effects of alpha-difluoromethylornithine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice. Clin Exp Metastasis (2003) 0.91
Prognostic value of ornithine decarboxylase and polyamines in human breast cancer: correlation with clinicopathologic parameters. Clin Cancer Res (1999) 0.88
Prognostic influence on survival of increased ornithine decarboxylase activity in human breast cancer. Clin Cancer Res (1996) 0.85
Influence of polyamines on in vitro and in vivo features of aggressive and metastatic behavior by human breast cancer cells. Clin Exp Metastasis (2002) 0.84
Involvement of the polyamine pathway in breast cancer progression. Cancer Lett (1995) 0.81
Cooperativity between the polyamine pathway and HER-2neu in transformation of human mammary epithelial cells in culture: role of the MAPK pathway. Int J Cancer (1998) 0.79
The role of mitogen-activated protein kinase activation in determining cellular outcomes in polyamine analogue-treated human melanoma cells. Cancer Res (2003) 0.79
Polyamine involvement in the growth of hormone-responsive and -resistant human breast cancer cells in culture. Cancer Res (1989) 0.76
Adjuvant systemic therapy for early breast cancer: progress and controversies. Clin Cancer Res (2001) 0.75
An evaluation of the involvement of polyamines in modulating MCF-7 human breast cancer cell proliferation and progesterone receptor levels by estrogen and antiestrogen. J Steroid Biochem (1987) 0.75
Daily or intermittent budesonide in preschool children with recurrent wheezing. N Engl J Med (2011) 4.09
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med (2011) 3.80
Classifying asthma severity in children: mismatch between symptoms, medication use, and lung function. Am J Respir Crit Care Med (2004) 2.46
Relative validity of food frequency questionnaire nutrient estimates in the Black Women's Health Study. Ann Epidemiol (2003) 2.11
Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription. J Biol Chem (2003) 1.98
Do oral corticosteroids reduce the severity of acute lower respiratory tract illnesses in preschool children with recurrent wheezing? J Allergy Clin Immunol (2013) 1.82
Asthma outcomes: exacerbations. J Allergy Clin Immunol (2012) 1.76
The biology of the opioid growth factor receptor (OGFr). Brain Res Brain Res Rev (2002) 1.71
The relationship of pulmonary artery pressure and survival in congenital diaphragmatic hernia. J Pediatr Surg (2004) 1.42
The OGF-OGFr axis utilizes the p16INK4a and p21WAF1/CIP1 pathways to restrict normal cell proliferation. Mol Biol Cell (2008) 1.25
Characterization of the intronic splicing silencers flanking FGFR2 exon IIIb. J Biol Chem (2005) 1.23
Patient characteristics associated with improved outcomes with use of an inhaled corticosteroid in preschool children at risk for asthma. J Allergy Clin Immunol (2009) 1.21
Low-dose naltrexone therapy improves active Crohn's disease. Am J Gastroenterol (2007) 1.19
A dynamic model for genome-wide association studies. Hum Genet (2011) 1.15
Method of mutation analysis may contribute to discrepancies in reports of (V599E)BRAF mutation frequencies in melanocytic neoplasms. J Invest Dermatol (2004) 1.13
Characterization of the CCK-C (cancer) receptor in human pancreatic cancer. Int J Mol Med (2002) 1.10
Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing. Proc Natl Acad Sci U S A (2007) 1.00
A double blind, placebo-controlled, randomized crossover study of the acute metabolic effects of olanzapine in healthy volunteers. PLoS One (2011) 0.99
Correlation between serum levels of insulin-like growth factor 1, dehydroepiandrosterone sulfate, and dihydrotestosterone and acne lesion counts in adult women. Arch Dermatol (2005) 0.98
The opioid growth factor (OGF)-OGF receptor axis uses the p16 pathway to inhibit head and neck cancer. Cancer Res (2007) 0.96
Region-specific distribution of human immunodeficiency virus type 1 long terminal repeats containing specific configurations of CCAAT/enhancer-binding protein site II in brains derived from demented and nondemented patients. J Neurovirol (2004) 0.94
Identification and characterization of the murine ortholog (brms1) of breast-cancer metastasis suppressor 1 (BRMS1). Int J Cancer (2002) 0.93
Combination chemotherapy with gemcitabine and biotherapy with opioid growth factor (OGF) enhances the growth inhibition of pancreatic adenocarcinoma. Cancer Chemother Pharmacol (2005) 0.93
Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One (2013) 0.91
Metastasis of hormone-independent breast cancer to lung and bone is decreased by alpha-difluoromethylornithine treatment. Breast Cancer Res (2005) 0.91
Effects of alpha-difluoromethylornithine on local recurrence and pulmonary metastasis from MDA-MB-435 breast cancer xenografts in nude mice. Clin Exp Metastasis (2003) 0.91
Functional significance of gastrin gene expression in human cancer cells. Regul Pept (2004) 0.90
Correlation between presumed sinusitis-induced pain and paranasal sinus computed tomographic findings. Ann Allergy Asthma Immunol (2002) 0.89
The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancer. Mol Cancer (2008) 0.89
Specific sequence configurations of HIV-1 LTR G/C box array result in altered recruitment of Sp isoforms and correlate with disease progression. J Neuroimmunol (2004) 0.88
Does agreement on institutional values and leadership issues between deans and surgery chairs predict their institutions' performance? Acad Med (2007) 0.87
Follicle-stimulating hormone induction of ovarian insulin-like growth factor-binding protein-3 transcription requires a TATA box-binding protein and the protein kinase A and phosphatidylinositol-3 kinase pathways. Mol Endocrinol (2005) 0.87
Dependence on nuclear localization signals of the opioid growth factor receptor in the regulation of cell proliferation. Exp Biol Med (Maywood) (2009) 0.86
Influence of polyamines on in vitro and in vivo features of aggressive and metastatic behavior by human breast cancer cells. Clin Exp Metastasis (2002) 0.84
The functional significance of the cholecystokinin-C (CCK-C) receptor in human pancreatic cancer. Pancreas (2004) 0.84
Opioid growth factor enhances tumor growth inhibition and increases the survival of paclitaxel-treated mice with squamous cell carcinoma of the head and neck. Cancer Chemother Pharmacol (2005) 0.83
Particle-mediated gene transfer of opioid growth factor receptor cDNA regulates cell proliferation of the corneal epithelium. Cornea (2005) 0.83
Overexpression of the opioid growth factor receptor potentiates growth inhibition in human pancreatic cancer cells. Int J Oncol (2007) 0.83
Influence of omega-3 fatty acids on Tamoxifen-induced suppression of rat mammary carcinogenesis. Int J Cancer (2013) 0.82
The impact of fish oil on the chemopreventive efficacy of tamoxifen against development of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. Cancer Prev Res (Phila) (2010) 0.82
The expression and function of the OGF-OGFr axis - a tonically active negative regulator of growth - in COS cells. Neuropeptides (2003) 0.81
Insulin-like growth factor-binding protein-3 in porcine ovarian granulosa cells: gene cloning, promoter mapping, and follicle-stimulating hormone regulation. Endocrinology (2004) 0.81
Activation of protein kinase A (PKA) signaling mitigates the antiproliferative and antiinvasive effects of alpha-difluoromethylornithine in breast cancer cells. Breast Cancer Res Treat (2007) 0.81
A conceptual framework for pharmacodynamic genome-wide association studies in pharmacogenomics. Drug Discov Today (2011) 0.81
Interaction between Polyamines and the Mitogen-Activated Protein Kinase Pathway in the Regulation of Cell Cycle Variables in Breast Cancer Cells. Cancer Res (2005) 0.81
Enhanced growth inhibition of squamous cell carcinoma of the head and neck by combination therapy of paclitaxel and opioid growth factor. Int J Oncol (2005) 0.80
Overexpression of the opioid growth factor receptor downregulates cell proliferation of human squamous carcinoma cells of the head and neck. Int J Mol Med (2007) 0.80
A retrospective chart review to identify perinatal factors associated with food allergies. Nutr J (2012) 0.80
Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. Int J Oncol (2011) 0.80
A statistical model for genetic mapping of viral infection by integrating epidemiological behavior. Stat Appl Genet Mol Biol (2009) 0.79
Opioid growth factor inhibits intimal hyperplasia in balloon-injured rat carotid artery. J Vasc Surg (2003) 0.79
The effects of Tamoxifen and fish oil on mammary carcinogenesis in polyoma middle T transgenic mice. Horm Cancer (2011) 0.78
The TATA binding protein associated factor 4b (TAF4b) mediates FSH stimulation of the IGFBP-3 promoter in cultured porcine ovarian granulosa cells. Mol Cell Endocrinol (2007) 0.78
Respiratory systems abnormalities and clinical milestones for patients with amyotrophic lateral sclerosis with emphasis upon survival. Amyotroph Lateral Scler (2007) 0.78
Effects of polyamine synthesis inhibitors on primary tumor features and metastatic capacity of human breast cancer cells. Clin Exp Metastasis (2005) 0.78
Interdisciplinary graduate education: a case study. Cell (2011) 0.78
Fish oil alters tamoxifen-modulated expression of mRNAs that encode genes related to differentiation, proliferation, metastasis, and immune response in rat mammary tumors. Nutr Cancer (2012) 0.77
Role of non-receptor and receptor tyrosine kinases (TKs) in the antitumor action of alpha-difluoromethylornithine (DFMO) in breast cancer cells. Breast Cancer Res Treat (2007) 0.77
Most nocturnal asthma symptoms occur outside of exacerbations and associate with morbidity. J Allergy Clin Immunol (2011) 0.77
Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. Breast Cancer Res Treat (2006) 0.77
ITGB5 and AGFG1 variants are associated with severity of airway responsiveness. BMC Med Genet (2013) 0.76
Death receptor apoptosis signaling mediated by FADD in CD30-positive lymphoproliferative disorders involving the skin. Am J Surg Pathol (2005) 0.76
Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells. Breast Cancer Res Treat (2007) 0.76
Fish Oil Enhances T Cell Function and Tumor Infiltration and Is Correlated With a Cancer Prevention Effect in HER-2/neu But Not PyMT Transgenic Mice. Nutr Cancer (2015) 0.76
Biological activity of the S-adenosylmethionine decarboxylase inhibitor SAM486A in human breast cancer cells in vitro and in vivo. Int J Oncol (2004) 0.76
Treatment of Wilms tumor-related hypertension with losartan and captopril. Pediatr Nephrol (2004) 0.75
Targeted overexpression of OGFr in epithelium of transgenic mice suppresses cell proliferation and impairs full-thickness wound closure. Am J Physiol Regul Integr Comp Physiol (2012) 0.75
Effects of alpha-difluoromethylornithine on thrombospondin-1 production by human breast cancer cells. Int J Oncol (2007) 0.75
Dermatology department endowments. J Am Acad Dermatol (2010) 0.75