Published in Development on January 26, 2005
Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling. Cold Spring Harb Perspect Biol (2010) 3.02
Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver. Proc Natl Acad Sci U S A (2006) 2.25
Small RNA and transcriptional upregulation. Wiley Interdiscip Rev RNA (2011) 1.36
Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans. Mol Pain (2006) 1.30
Estrogen-related receptor gamma promotes mesenchymal-to-epithelial transition and suppresses breast tumor growth. Cancer Res (2011) 0.96
Modeling chromosomes in mouse to explore the function of genes, genomic disorders, and chromosomal organization. PLoS Genet (2006) 0.95
A nonneural epithelial domain of embryonic cranial neural folds gives rise to ectomesenchyme. Proc Natl Acad Sci U S A (2008) 0.88
Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin. PLoS Genet (2012) 0.85
Conserved elements within first intron of aquaporin-5 (Aqp5) function as transcriptional enhancers. Biochem Biophys Res Commun (2007) 0.82
A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population. BMC Cancer (2008) 0.82
Characterization of the intronic portion of cadherin superfamily members, common cancer orchestrators. Eur J Hum Genet (2012) 0.77
Inducing gene expression by targeting promoter sequences using small activating RNAs. J Biol Methods (2015) 0.77
Self-recognition of high-mannose type glycans mediating adhesion of embryonal fibroblasts. Glycoconj J (2012) 0.77
Controlled somatic and germline copy number variation in the mouse model. Curr Genomics (2010) 0.76
Digital PCR identifies changes in CDH1 (E-cadherin) transcription pattern in intestinal-type gastric cancer. Oncotarget (2016) 0.75
E-cadherin roles in animal biology: A perspective on thyroid hormone-influence. Cell Commun Signal (2016) 0.75
Historical Perspective on Familial Gastric Cancer. Cell Mol Gastroenterol Hepatol (2017) 0.75
Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells. Science (2012) 4.51
Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell (2002) 3.37
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nat Cell Biol (2011) 3.25
Beta-catenin is dispensable for hematopoiesis and lymphopoiesis. J Exp Med (2004) 3.16
Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev Cell (2003) 3.15
Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148. J Cell Biol (2003) 2.92
Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells. Science (2004) 2.82
The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility. J Cell Biol (2003) 2.77
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J (2005) 2.72
E-cadherin is a survival factor for the lactating mouse mammary gland. Mech Dev (2002) 2.63
Mediator is a transducer of Wnt/beta-catenin signaling. J Biol Chem (2006) 2.51
Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell (2006) 2.40
Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev (2003) 2.34
Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm. Dev Cell (2002) 2.14
Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis. Blood (2007) 2.06
Reptin and pontin antagonistically regulate heart growth in zebrafish embryos. Cell (2002) 2.03
Lineage-specific requirements of beta-catenin in neural crest development. J Cell Biol (2002) 1.87
Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis. Proc Natl Acad Sci U S A (2007) 1.80
Protocadherins. Curr Opin Cell Biol (2002) 1.77
Long-range upstream and downstream enhancers control distinct subsets of the complex spatiotemporal Sox9 expression pattern. Dev Biol (2006) 1.68
Lineage specification of parietal epithelial cells requires β-catenin/Wnt signaling. J Am Soc Nephrol (2011) 1.64
Abrogation of E-cadherin-mediated cell-cell contact in mouse embryonic stem cells results in reversible LIF-independent self-renewal. Stem Cells (2009) 1.63
Presenilin-dependent processing and nuclear function of gamma-protocadherins. J Biol Chem (2004) 1.57
Mammalian cadherins and protocadherins: about cell death, synapses and processing. Curr Opin Cell Biol (2005) 1.56
Maternal beta-catenin and E-cadherin in mouse development. Development (2004) 1.55
beta-Catenin regulates excitatory postsynaptic strength at hippocampal synapses. Proc Natl Acad Sci U S A (2007) 1.54
Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets. Nucleic Acids Res (2009) 1.52
Nanog is required for primitive endoderm formation through a non-cell autonomous mechanism. Dev Biol (2010) 1.50
Differential expression of individual gamma-protocadherins during mouse brain development. Mol Cell Neurosci (2005) 1.46
E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles. EMBO J (2003) 1.44
Protein kinase CKII regulates the interaction of beta-catenin with alpha-catenin and its protein stability. J Cell Sci (2002) 1.44
Beta-catenin-mediated cell-adhesion is vital for embryonic forebrain development. Dev Dyn (2005) 1.40
Trans-repression of beta-catenin activity by nuclear receptors. J Biol Chem (2003) 1.37
N-cadherin transsynaptically regulates short-term plasticity at glutamatergic synapses in embryonic stem cell-derived neurons. J Neurosci (2006) 1.36
The microphthalmia-associated transcription factor Mitf interacts with beta-catenin to determine target gene expression. Mol Cell Biol (2006) 1.31
E-cadherin inhibits cell surface localization of the pro-migratory 5T4 oncofetal antigen in mouse embryonic stem cells. Mol Biol Cell (2007) 1.26
Abnormal lens morphogenesis and ectopic lens formation in the absence of beta-catenin function. Genesis (2007) 1.22
Gene replacement reveals a specific role for E-cadherin in the formation of a functional trophectoderm. Development (2006) 1.17
Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos. Development (2005) 1.16
Differential control of Wnt target genes involves epigenetic mechanisms and selective promoter occupancy by T-cell factors. Mol Cell Biol (2007) 1.09
beta-Catenin is not required for proliferation and differentiation of epidermal mouse keratinocytes. J Cell Sci (2002) 1.09
Direct binding of Lef1 to sites in the boz promoter may mediate pre-midblastula-transition activation of boz expression. Dev Dyn (2003) 1.07
Canonical Wnt signaling transiently stimulates proliferation and enhances neurogenesis in neonatal neural progenitor cultures. Exp Cell Res (2006) 1.06
Inhibition of GSK3 differentially modulates NF-kappaB, CREB, AP-1 and beta-catenin signaling in hepatocytes, but fails to promote TNF-alpha-induced apoptosis. Exp Cell Res (2007) 1.06
Genetic dissection of cadherin function during nephrogenesis. Mol Cell Biol (2002) 1.06
Biological and mathematical modeling of melanocyte development. Development (2011) 1.02
N-cadherin deficiency impairs pericyte recruitment, and not endothelial differentiation or sprouting, in embryonic stem cell-derived angiogenesis. Exp Cell Res (2005) 1.02
E-cadherin is required for the correct formation of autotypic adherens junctions of the outer mesaxon but not for the integrity of myelinated fibers of peripheral nerves. Mol Cell Neurosci (2002) 1.01
E-cadherin is required for the proper activation of the Lifr/Gp130 signaling pathway in mouse embryonic stem cells. Development (2013) 0.96
Functional analysis of cis-regulatory elements controlling initiation and maintenance of early Cdx1 gene expression in the mouse. Dev Dyn (2002) 0.95
Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system. Eur J Neurosci (2008) 0.95
Canonical Wnt signaling controls proliferation of retinal stem/progenitor cells in postembryonic Xenopus eyes. Stem Cells (2008) 0.95
Oncogenic transformation by beta-catenin: deletion analysis and characterization of selected target genes. Oncogene (2002) 0.94
Beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos. Dev Dyn (2010) 0.93
Differential requirements for β-catenin during mouse development. Development (2012) 0.89
Analysis of regulatory elements of E-cadherin with reporter gene constructs in transgenic mouse embryos. Dev Dyn (2003) 0.88
Conditional inactivation of the E-cadherin gene in thyroid follicular cells affects gland development but does not impair junction formation. Endocrinology (2007) 0.87
N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation. Development (2010) 0.85
Le(x) glycan mediates homotypic adhesion of embryonal cells independently from E-cadherin: a preliminary note. Biochem Biophys Res Commun (2007) 0.85
Neural progenitors of the postnatal and adult mouse forebrain retain the ability to self-replicate, form neurospheres, and undergo multipotent differentiation in vivo. Stem Cells (2009) 0.84
Class I and III HDACs and loss of active chromatin features contribute to epigenetic silencing of CDX1 and EPHB tumor suppressor genes in colorectal cancer. Epigenetics (2011) 0.84
Modeling Wnt/β-Catenin Target Gene Expression in APC and Wnt Gradients Under Wild Type and Mutant Conditions. Front Physiol (2013) 0.83
Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression. Nucleic Acids Res (2012) 0.83
Snapshots of protein dynamics and post-translational modifications in one experiment--beta-catenin and its functions. Mol Cell Proteomics (2011) 0.83
Wnt3a-dependent and -independent protein interaction networks of chromatin-bound β-catenin in mouse embryonic stem cells. Mol Cell Proteomics (2013) 0.80
Cdx1::Cre allele for gene analysis in the extraembryonic ectoderm and the three germ layers of mice at mid-gastrulation. Genesis (2009) 0.79
Replacement of E-cadherin by N-cadherin in the mammary gland leads to fibrocystic changes and tumor formation. Breast Cancer Res (2011) 0.79
Acetylation of human TCF4 (TCF7L2) proteins attenuates inhibition by the HBP1 repressor and induces a conformational change in the TCF4::DNA complex. PLoS One (2013) 0.78
Silencing of the EPHB3 tumor-suppressor gene in human colorectal cancer through decommissioning of a transcriptional enhancer. Proc Natl Acad Sci U S A (2014) 0.78
4-Aminoethylamino-emodin--a novel potent inhibitor of GSK-3beta--acts as an insulin-sensitizer avoiding downstream effects of activated beta-catenin. J Cell Mol Med (2009) 0.77
Mathematical modelling suggests a differential impact of β-transducin repeat-containing protein paralogues on Wnt/β-catenin signalling dynamics. FEBS J (2015) 0.76