Published in J Cell Sci on February 01, 2005
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Clearing the dead: apoptotic cell sensing, recognition, engulfment, and digestion. Cold Spring Harb Perspect Biol (2013) 2.00
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Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer. Oncogene (2012) 1.33
TAM receptor ligands in lupus: protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosus. Arthritis Res Ther (2010) 1.27
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Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrin. Biol Cell (2012) 0.90
Increased hematopoietic cells in the mertk-/- mouse peritoneal cavity: a result of augmented migration. J Immunol (2010) 0.89
Integrin βν-mediated phagocytosis of apoptotic cells in Drosophila embryos. J Biol Chem (2011) 0.88
The urokinase plasminogen activator receptor promotes efferocytosis of apoptotic cells. J Biol Chem (2009) 0.88
Milk fat globule EGF factor 8 attenuates sepsis-induced apoptosis and organ injury in alcohol-intoxicated rats. Alcohol Clin Exp Res (2010) 0.88
A novel role for SED1 (MFG-E8) in maintaining the integrity of the epididymal epithelium. J Cell Sci (2009) 0.88
ATG proteins mediate efferocytosis and suppress inflammation in mammary involution. Autophagy (2013) 0.87
Apoptotic cell recognition receptors and scavenger receptors. Immunol Rev (2016) 0.87
Contribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and Autoimmunity. Front Immunol (2014) 0.86
Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinase. Mol Biol Cell (2012) 0.85
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TAM receptor deficiency affects adult hippocampal neurogenesis. Metab Brain Dis (2014) 0.82
Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis. J Lipid Res (2015) 0.81
Cleavage of Mer tyrosine kinase (MerTK) from the cell surface contributes to the regulation of retinal phagocytosis. J Biol Chem (2014) 0.81
Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis. Am J Physiol Renal Physiol (2014) 0.81
Role of plasma kallikrein-kinin system activation in synovial recruitment of endothelial progenitor cells in experimental arthritis. Arthritis Rheum (2012) 0.80
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Mertk deficiency affects macrophage directional migration via disruption of cytoskeletal organization. PLoS One (2015) 0.80
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High molecular weight kininogen binds phosphatidylserine and opsonizes urokinase plasminogen activator receptor-mediated efferocytosis. J Immunol (2014) 0.80
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Genetic polymorphism of the growth arrest-specific 6 gene is associated with cutaneous vasculitis in Taiwanese patients with systemic lupus erythematosus. Clin Rheumatol (2012) 0.79
Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase. Cell Commun Signal (2016) 0.79
Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk. Oncogene (2014) 0.78
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Regulation of phagocytosis by Rho GTPases. Small GTPases (2015) 0.78
TAM receptor tyrosine kinases as emerging targets of innate immune checkpoint blockade for cancer therapy. Immunol Rev (2017) 0.77
The SH3 regulatory domain of the hematopoietic cell kinase Hck binds ELMO via its polyproline motif. FEBS Open Bio (2015) 0.77
Molecular insights of Gas6/TAM in cancer development and therapy. Cell Death Dis (2017) 0.76
Maxed out macs: physiologic cell clearance as a function of macrophage phagocytic capacity. FEBS J (2016) 0.75
Tyr724 phosphorylation of ELMO1 by Src is involved in cell spreading and migration via Rac1 activation. Cell Commun Signal (2015) 0.75
Integrin αVβ5-mediated Removal of Apoptotic Cell Debris by the Eye Lens and Its Inhibition by UV Light Exposure. J Biol Chem (2015) 0.75
Identification of macrophage genes responsive to extracellular acidification. Inflamm Res (2013) 0.75
The Mertk receptor tyrosine kinase promotes T-B interaction stimulated by IgD B-cell receptor cross-linking. J Autoimmun (2014) 0.75
Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy. Oncotarget (2016) 0.75
MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP dissociation inhibitor alpha from the GDI/CHM family of RAB GTPase effectors. Exp Eye Res (2015) 0.75
Selective remodeling: refining neural connectivity at the neuromuscular junction. PLoS Biol (2009) 0.75
The Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer Therapy. Cancers (Basel) (2016) 0.75
From leukocyte recruitment to resolution of inflammation: the cardinal role of integrins. J Leukoc Biol (2017) 0.75
The Procoagulant Activity of Apoptotic Cells Is Mediated by Interaction with Factor XII. Front Immunol (2017) 0.75
The Pathophysiological Role of Microglia in Dynamic Surveillance, Phagocytosis and Structural Remodeling of the Developing CNS. Front Mol Neurosci (2017) 0.75
Fas engagement induces neurite growth through ERK activation and p35 upregulation. Nat Cell Biol (2003) 2.64
Proline cis-trans isomerization controls autoinhibition of a signaling protein. Mol Cell (2007) 2.44
Development and mapping of EST-derived simple sequence repeat markers for hexaploid wheat. Genome (2004) 2.39
The emergence of Ug99 races of the stem rust fungus is a threat to world wheat production. Annu Rev Phytopathol (2011) 2.35
Ezrin-radixin-moesin (ERM)-binding phosphoprotein 50 organizes ERM proteins at the apical membrane of polarized epithelia. Proc Natl Acad Sci U S A (2004) 2.31
Phosphatidylserine recognition by phagocytes: a view to a kill. Trends Cell Biol (2006) 2.27
PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling. EMBO J (2006) 2.16
PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1. Mol Cell Biol (2003) 2.14
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ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts. J Cell Biol (2002) 2.05
Microsatellite-based deletion bin system for the establishment of genetic-physical map relationships in wheat (Triticum aestivum L.). Funct Integr Genomics (2004) 1.93
The Sept4 septin locus is required for sperm terminal differentiation in mice. Dev Cell (2005) 1.92
Invasive glioblastoma cells acquire stemness and increased Akt activation. Neoplasia (2010) 1.71
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Synergy in tumor suppression by direct interaction of neutral endopeptidase with PTEN. Cancer Cell (2004) 1.57
NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands. Mol Cell Biol (2007) 1.52
The opsonin MFG-E8 is a ligand for the alphavbeta5 integrin and triggers DOCK180-dependent Rac1 activation for the phagocytosis of apoptotic cells. Exp Cell Res (2004) 1.37
Structural basis for regulation of the Crk signaling protein by a proline switch. Nat Chem Biol (2010) 1.30
miR-29b and miR-125a regulate podoplanin and suppress invasion in glioblastoma. Genes Chromosomes Cancer (2010) 1.22
NHERF1/EBP50 is a new marker in colorectal cancer. Neoplasia (2010) 1.22
Comparative evaluation of ropivacaine and lignocaine with ropivacaine, lignocaine and clonidine combination during peribulbar anaesthesia for phacoemulsification cataract surgery. Indian J Anaesth (2012) 1.14
Transglutaminase 2 is needed for the formation of an efficient phagocyte portal in macrophages engulfing apoptotic cells. J Immunol (2009) 1.13
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Loss of PTEN binding adapter protein NHERF1 from plasma membrane in glioblastoma contributes to PTEN inactivation. Cancer Res (2010) 1.11
Emerging roles for crk in human cancer. Genes Cancer (2010) 1.09
Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat Chem Biol (2012) 1.08
RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN. Cancer Res (2009) 1.08
The presumptive phosphatidylserine receptor is dispensable for innate anti-inflammatory recognition and clearance of apoptotic cells. J Biol Chem (2005) 1.06
A consensus map for Ug99 stem rust resistance loci in wheat. Theor Appl Genet (2014) 1.05
C-terminal SH3 domain of CrkII regulates the assembly and function of the DOCK180/ELMO Rac-GEF. J Cell Physiol (2005) 1.04
Vitamin K2 induces autophagy and apoptosis simultaneously in leukemia cells. Autophagy (2008) 1.03
Overexpression of ezrin inactivates NF2 tumor suppressor in glioblastoma. Neuro Oncol (2010) 1.00
Moesin is a glioma progression marker that induces proliferation and Wnt/β-catenin pathway activation via interaction with CD44. Cancer Res (2012) 1.00
Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferons. Arthritis Rheum (2012) 1.00
Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3 domain. Oncogene (2005) 0.98
PTEN-induction in U251 glioma cells decreases the expression of insulin-like growth factor binding protein-2. Biochem Biophys Res Commun (2005) 0.97
Lr67/Yr46 confers adult plant resistance to stem rust and powdery mildew in wheat. Theor Appl Genet (2014) 0.96
TAM receptors in apoptotic cell clearance, autoimmunity, and cancer. Autoimmunity (2013) 0.93
A NPxY-independent beta5 integrin activation signal regulates phagocytosis of apoptotic cells. Biochem Biophys Res Commun (2007) 0.93
NHERF1: molecular brake on the PI3K pathway in breast cancer. Breast Cancer Res (2008) 0.91
Control of Alzheimer's amyloid beta toxicity by the high molecular weight immunophilin FKBP52 and copper homeostasis in Drosophila. PLoS One (2010) 0.91
Proapoptotic function of the nuclear Crk II adaptor protein. Biochemistry (2007) 0.89
Characterization of the biochemical and biophysical properties of the phosphatidylserine receptor (PS-R) gene product. Mol Cell Biochem (2007) 0.89
The urokinase plasminogen activator receptor promotes efferocytosis of apoptotic cells. J Biol Chem (2009) 0.88
ATG proteins mediate efferocytosis and suppress inflammation in mammary involution. Autophagy (2013) 0.87
Drug-induced reactivation of apoptosis abrogates HIV-1 infection. PLoS One (2013) 0.87
Sphingosine kinase 1 overexpression is regulated by signaling through PI3K, AKT2, and mTOR in imatinib-resistant chronic myeloid leukemia cells. Exp Hematol (2011) 0.86
Crk and ABI1: binary molecular switches that regulate abl tyrosine kinase and signaling to the cytoskeleton. Genes Cancer (2012) 0.86
Externalized glycolytic enzymes are novel, conserved, and early biomarkers of apoptosis. J Biol Chem (2012) 0.86
Insulin-like growth factor I regulates G2/M progression through mammalian target of rapamycin signaling in oligodendrocyte progenitors. Glia (2012) 0.85
Resistance to stem rust Ug99 in six bread wheat cultivars maps to chromosome 6DS. Theor Appl Genet (2014) 0.84
Molecular Mapping and Validation of SrND643: A New Wheat Gene for Resistance to the Stem Rust Pathogen Ug99 Race Group. Phytopathology (2015) 0.83
Crk at the quarter century mark: perspectives in signaling and cancer. J Cell Biochem (2014) 0.83
PHLPP2 suppresses the NF-κB pathway by inactivating IKKβ kinase. Oncotarget (2014) 0.83
Real-time fluorescent resonance energy transfer analysis to monitor drug resistance in chronic myelogenous leukemia. Mol Cancer Ther (2010) 0.82
A novel role for the immunophilin FKBP52 in copper transport. J Biol Chem (2004) 0.81
High molecular weight kininogen binds phosphatidylserine and opsonizes urokinase plasminogen activator receptor-mediated efferocytosis. J Immunol (2014) 0.80
NHERF1/EBP50 is an organizer of polarity structures and a diagnostic marker in ependymoma. Acta Neuropathol Commun (2015) 0.79
Measurement of cytoplasmic to nuclear translocation. Curr Protoc Cytom (2009) 0.79
Commentary: The carboxyl-terminal Crk SH3 domain: Regulatory strategies and new perspectives. FEBS Lett (2012) 0.79
Identification and molecular tagging of a gene from PI 289824 conferring resistance to leaf rust (Puccinia triticina) in wheat. Theor Appl Genet (2005) 0.76
Apoptosis: conserved roles for integrins in clearance. Curr Biol (2010) 0.76
Excellent outcome of Aspergillous endophthalmitis in a case of allergic bronchopulmonary aspergillosis. Indian J Ophthalmol (2014) 0.75
Haemodynamic and intraocular pressure changes during peribulbar anaesthesia with ropivacaine and clonidine in phacoemulsification cataract surgery. Indian J Anaesth (2012) 0.75
Ocular tissue responses to sex hormones. Indian J Endocrinol Metab (2012) 0.75
Regeneration after death: Vav3 to the rescue. Blood (2009) 0.75
Prevalence of Sexually Transmitted Infections (HIV, Hepatitis B, Herpes Simplex Type 2 and Syphilis) Among Asymptomatic Pregnant Women. J Obstet Gynaecol India (2012) 0.75
Unusual skull tumors with psammomatoid bodies: a diagnostic challenge. Clin Neuropathol (2017) 0.75
Corrigendum: Unlocking the genetic diversity of Creole wheats. Sci Rep (2016) 0.75
CFS-SMO based classification of breast density using multiple texture models. Med Biol Eng Comput (2014) 0.75
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Zinc phthalocyanine thin film and chemical analyte interaction studies by density functional theory and vibrational techniques. J Phys Condens Matter (2009) 0.75
Progressive leg pain and weakness. JAMA Neurol (2013) 0.75