Wolfgang Hammerschmidt

Author PubWeight™ 52.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis. PLoS Biol 2005 2.08
2 Conditional immortalization of human B cells by CD40 ligation. PLoS One 2008 1.89
3 Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes. Proc Natl Acad Sci U S A 2006 1.81
4 Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. PLoS Pathog 2010 1.80
5 The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold. Proc Natl Acad Sci U S A 2003 1.75
6 Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production. J Immunol 2012 1.71
7 Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus. J Cell Sci 2003 1.62
8 Latent membrane protein 1 is critical for efficient growth transformation of human B cells by epstein-barr virus. Cancer Res 2003 1.56
9 Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival. Blood 2007 1.50
10 CD8 T cell recognition of endogenously expressed epstein-barr virus nuclear antigen 1. J Exp Med 2004 1.47
11 Latent membrane protein 1 of Epstein-Barr virus coordinately regulates proliferation with control of apoptosis. Oncogene 2005 1.47
12 AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome. Proc Natl Acad Sci U S A 2009 1.46
13 Epstein-Barr virus mRNA export factor EB2 is essential for production of infectious virus. J Virol 2002 1.36
14 Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins. Proc Natl Acad Sci U S A 2008 1.36
15 Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells. Blood 2010 1.35
16 CpG-methylation regulates a class of Epstein-Barr virus promoters. PLoS Pathog 2010 1.28
17 Epstein-Barr virus nuclear antigen 2 (EBNA2) gene deletion is consistently linked with EBNA3A, -3B, and -3C expression in Burkitt's lymphoma cells and with increased resistance to apoptosis. J Virol 2005 1.22
18 Rescue of "crippled" germinal center B cells from apoptosis by Epstein-Barr virus. Blood 2005 1.18
19 The EBV immunoevasins vIL-10 and BNLF2a protect newly infected B cells from immune recognition and elimination. PLoS Pathog 2012 1.08
20 B cells immortalized by a mini-Epstein-Barr virus encoding a foreign antigen efficiently reactivate specific cytotoxic T cells. Blood 2002 1.08
21 Identification of Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) target proteins by proteome analysis: activation of EBNA2 in conditionally immortalized B cells reflects early events after infection of primary B cells by EBV. J Virol 2004 1.06
22 A somatic knockout of CBF1 in a human B-cell line reveals that induction of CD21 and CCR7 by EBNA-2 is strictly CBF1 dependent and that downregulation of immunoglobulin M is partially CBF1 independent. J Virol 2005 1.03
23 Human B cells on their route to latent infection--early but transient expression of lytic genes of Epstein-Barr virus. Eur J Cell Biol 2011 1.02
24 BZLF1 governs CpG-methylated chromatin of Epstein-Barr Virus reversing epigenetic repression. PLoS Pathog 2012 1.01
25 RNAs in Epstein-Barr virions control early steps of infection. Proc Natl Acad Sci U S A 2012 1.01
26 Latent membrane protein 1 of Epstein-Barr virus induces CD83 by the NF-kappaB signaling pathway. J Virol 2003 0.99
27 Epstein-Barr virus nuclear antigen 1 evades direct immune recognition by CD4+ T helper cells. Eur J Immunol 2004 0.99
28 Toll-like receptor agonists synergistically increase proliferation and activation of B cells by epstein-barr virus. J Virol 2010 0.97
29 Functional analysis of Epstein-Barr virus SM protein: identification of amino acids essential for structure, transactivation, splicing inhibition, and virion production. J Virol 2004 0.97
30 The lytic phase of epstein-barr virus requires a viral genome with 5-methylcytosine residues in CpG sites. J Virol 2011 0.95
31 CMV-specific TCR-transgenic T cells for immunotherapy. J Immunol 2009 0.93
32 A virus-like particle-based Epstein-Barr virus vaccine. J Virol 2011 0.92
33 Epstein-Barr virus and host cell methylation: regulation of latency, replication and virus reactivation. Curr Opin Virol 2013 0.91
34 Epstein-Barr virus exploits BSAP/Pax5 to achieve the B-cell specificity of its growth-transforming program. J Virol 2007 0.91
35 c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs. Nucleic Acids Res 2013 0.90
36 EBV-gp350 confers B-cell tropism to tailored exosomes and is a neo-antigen in normal and malignant B cells--a new option for the treatment of B-CLL. PLoS One 2011 0.85
37 HLA type-independent generation of antigen-specific T cells for adoptive immunotherapy. Eur J Immunol 2005 0.85
38 High level of transgene expression in primary chronic lymphocytic leukemia cells using helper-virus-free recombinant Epstein-Barr virus vectors. Exp Hematol 2003 0.85
39 Activated B cells mediate efficient expansion of rare antigen-specific T cells. Hum Immunol 2007 0.83
40 Efficient somatic gene targeting in the lymphoid human cell line DG75. Gene 2004 0.80
41 Selection of CMV-specific CD8+ and CD4+ T cells by mini-EBV-transformed B cell lines. Eur J Immunol 2005 0.79
42 Different roles of the human Orc6 protein in the replication initiation process. Cell Mol Life Sci 2011 0.78
43 Restricted expression of Epstein-Barr virus latent genes in murine B cells derived from embryonic stem cells. PLoS One 2008 0.77
44 Virus-specific T cells for therapy--approaches, problems, solutions. Eur J Cell Biol 2011 0.77
45 Conditional gene vectors regulated in cis. Nucleic Acids Res 2008 0.77
46 The CR4 region of EBNA2 confers viability of Epstein-Barr virus-transformed B cells by CBF1-independent signalling. J Gen Virol 2006 0.75
47 [Lifelong healing via gene transfer - reality or utopia? Stable versus transient gene transfer]. Pharm Unserer Zeit 2011 0.75