Published in Proc Natl Acad Sci U S A on December 22, 2009
An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells. Cell Host Microbe (2010) 2.23
Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. PLoS Pathog (2010) 1.80
Viral latency and its regulation: lessons from the gamma-herpesviruses. Cell Host Microbe (2010) 1.70
A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas. J Virol (2010) 1.50
CpG-methylation regulates a class of Epstein-Barr virus promoters. PLoS Pathog (2010) 1.28
Regulation of the latent-lytic switch in Epstein-Barr virus. Semin Cancer Biol (2014) 1.15
An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model. J Virol (2012) 1.10
The EBV immunoevasins vIL-10 and BNLF2a protect newly infected B cells from immune recognition and elimination. PLoS Pathog (2012) 1.08
RNAs in Epstein-Barr virions control early steps of infection. Proc Natl Acad Sci U S A (2012) 1.01
BZLF1 governs CpG-methylated chromatin of Epstein-Barr Virus reversing epigenetic repression. PLoS Pathog (2012) 1.01
Role for early-differentiated natural killer cells in infectious mononucleosis. Blood (2014) 0.99
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Toll-like receptor agonists synergistically increase proliferation and activation of B cells by epstein-barr virus. J Virol (2010) 0.97
Epigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor. PLoS One (2011) 0.97
Viral genome methylation differentially affects the ability of BZLF1 versus BRLF1 to activate Epstein-Barr virus lytic gene expression and viral replication. J Virol (2012) 0.95
The lytic phase of epstein-barr virus requires a viral genome with 5-methylcytosine residues in CpG sites. J Virol (2011) 0.95
Dynamic chromatin environment of key lytic cycle regulatory regions of the Epstein-Barr virus genome. J Virol (2011) 0.95
Genome-wide DNA methylation as an epigenetic consequence of Epstein-Barr virus infection of immortalized keratinocytes. J Virol (2014) 0.93
Identification of disease-associated DNA methylation in B cells from Crohn's disease and ulcerative colitis patients. Dig Dis Sci (2012) 0.92
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Epigenetic regulation of EBV and KSHV latency. Curr Opin Virol (2013) 0.90
c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs. Nucleic Acids Res (2013) 0.90
The B-cell specific transcription factor, Oct-2, promotes Epstein-Barr virus latency by inhibiting the viral immediate-early protein, BZLF1. PLoS Pathog (2012) 0.89
Unexpected patterns of Epstein-Barr virus transcription revealed by a high throughput PCR array for absolute quantification of viral mRNA. Virology (2014) 0.89
Epstein-Barr virus interactions with the Bcl-2 protein family and apoptosis in human tumor cells. J Zhejiang Univ Sci B (2013) 0.87
Genome-wide analysis of Epstein-Barr virus Rta DNA binding. J Virol (2012) 0.87
Dynamic Epstein-Barr virus gene expression on the path to B-cell transformation. Adv Virus Res (2014) 0.86
Shutoff of BZLF1 gene expression is necessary for immortalization of primary B cells by Epstein-Barr virus. J Virol (2012) 0.86
The B-cell-specific transcription factor and master regulator Pax5 promotes Epstein-Barr virus latency by negatively regulating the viral immediate early protein BZLF1. J Virol (2013) 0.83
Epstein-Barr virus (EBV) Rta-mediated EBV and Kaposi's sarcoma-associated herpesvirus lytic reactivations in 293 cells. PLoS One (2011) 0.82
Epstein-Barr virus transcription activator R upregulates BARF1 expression by direct binding to its promoter, independent of methylation. J Virol (2012) 0.82
The ZIIR element of the Epstein-Barr virus BZLF1 promoter plays a central role in establishment and maintenance of viral latency. J Virol (2011) 0.82
B lymphocytes from patients with a hypomorphic mutation in STAT3 resist Epstein-Barr virus-driven cell proliferation. J Virol (2013) 0.82
Epstein-Barr virus LF2 protein regulates viral replication by altering Rta subcellular localization. J Virol (2010) 0.82
Epstein-Barr virus transcription factor Zta acts through distal regulatory elements to directly control cellular gene expression. Nucleic Acids Res (2015) 0.82
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Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing. J Exp Med (2016) 0.79
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Epstein-Barr virus Zta-induced immunomodulators from nasopharyngeal carcinoma cells upregulate interleukin-10 production from monocytes. J Virol (2011) 0.79
Extracellular vesicles during Herpes Simplex Virus type 1 infection: an inquire. Virol J (2016) 0.79
DNA Damage Signaling Is Induced in the Absence of Epstein-Barr Virus (EBV) Lytic DNA Replication and in Response to Expression of ZEBRA. PLoS One (2015) 0.78
The effect of Epstein-Barr virus Latent Membrane Protein 2 expression on the kinetics of early B cell infection. PLoS One (2013) 0.78
Inhibition of germinal centre apoptotic programmes by epstein-barr virus. Adv Hematol (2011) 0.78
5-hydroxymethylation of the EBV genome regulates the latent to lytic switch. Proc Natl Acad Sci U S A (2015) 0.77
ERK/c-Jun Recruits Tet1 to Induce Zta Expression and Epstein-Barr Virus Reactivation through DNA Demethylation. Sci Rep (2016) 0.75
Epstein-Barr virus lytic reactivation regulation and its pathogenic role in carcinogenesis. Int J Biol Sci (2016) 0.75
Restricted TET2 Expression in Germinal Center Type B Cells Promotes Stringent Epstein-Barr Virus Latency. J Virol (2017) 0.75
Repression of CIITA by the Epstein-Barr virus transcription factor Zta is independent of its dimerization and DNA binding. J Gen Virol (2015) 0.75
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Noise cancellation: viral fine tuning of the cellular environment for its own genome replication. PLoS Pathog (2010) 0.75
Epstein-Barr virus in the pathogenesis of oral cancers. Oral Dis (2017) 0.75
Epstein-Barr Virus Rta-Mediated Accumulation of DNA Methylation Interferes with CTCF Binding in both Host and Viral Genomes. J Virol (2017) 0.75
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Infectious Epstein-Barr virus lacking major glycoprotein BLLF1 (gp350/220) demonstrates the existence of additional viral ligands. J Virol (2000) 2.04
Glycoprotein gp110 of Epstein-Barr virus determines viral tropism and efficiency of infection. Proc Natl Acad Sci U S A (2002) 1.99
Conditional immortalization of human B cells by CD40 ligation. PLoS One (2008) 1.89
The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genome. Nat Genet (2004) 1.82
CD8+ immunodominance among Epstein-Barr virus lytic cycle antigens directly reflects the efficiency of antigen presentation in lytically infected cells. J Exp Med (2005) 1.61
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Downregulation of TAP1 in B lymphocytes by cellular and Epstein-Barr virus-encoded interleukin-10. Blood (1997) 1.47
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Epstein-Barr virus mRNA export factor EB2 is essential for production of infectious virus. J Virol (2002) 1.36
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ZEB1 regulates the latent-lytic switch in infection by Epstein-Barr virus. PLoS Pathog (2007) 1.33
BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186. J Virol (2005) 1.30
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Epstein-Barr virus BZLF1 gene, a switch from latency to lytic infection, is expressed as an immediate-early gene after primary infection of B lymphocytes. J Virol (2006) 1.24
Methylation-dependent binding of the epstein-barr virus BZLF1 protein to viral promoters. PLoS Pathog (2009) 1.20
Methylated DNA recognition during the reversal of epigenetic silencing is regulated by cysteine and serine residues in the Epstein-Barr virus lytic switch protein. PLoS Pathog (2008) 1.14
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The Epstein-Barr virus lytic cycle activator Zta interacts with methylated ZRE in the promoter of host target gene egr1. J Gen Virol (2009) 0.98
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Quantitative evaluation of the role of Epstein-Barr virus immediate-early protein BZLF1 in B-cell transformation. J Gen Virol (2009) 0.89
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Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis. PLoS Biol (2005) 2.08
Conditional immortalization of human B cells by CD40 ligation. PLoS One (2008) 1.89
Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes. Proc Natl Acad Sci U S A (2006) 1.81
Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. PLoS Pathog (2010) 1.80
The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold. Proc Natl Acad Sci U S A (2003) 1.75
Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production. J Immunol (2012) 1.71
Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus. J Cell Sci (2003) 1.62
Latent membrane protein 1 is critical for efficient growth transformation of human B cells by epstein-barr virus. Cancer Res (2003) 1.56
Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival. Blood (2007) 1.50
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Latent membrane protein 1 of Epstein-Barr virus coordinately regulates proliferation with control of apoptosis. Oncogene (2005) 1.47
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Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins. Proc Natl Acad Sci U S A (2008) 1.36
Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells. Blood (2010) 1.35
CpG-methylation regulates a class of Epstein-Barr virus promoters. PLoS Pathog (2010) 1.28
Rescue of "crippled" germinal center B cells from apoptosis by Epstein-Barr virus. Blood (2005) 1.18
The EBV immunoevasins vIL-10 and BNLF2a protect newly infected B cells from immune recognition and elimination. PLoS Pathog (2012) 1.08
B cells immortalized by a mini-Epstein-Barr virus encoding a foreign antigen efficiently reactivate specific cytotoxic T cells. Blood (2002) 1.08
Human B cells on their route to latent infection--early but transient expression of lytic genes of Epstein-Barr virus. Eur J Cell Biol (2011) 1.02
RNAs in Epstein-Barr virions control early steps of infection. Proc Natl Acad Sci U S A (2012) 1.01
BZLF1 governs CpG-methylated chromatin of Epstein-Barr Virus reversing epigenetic repression. PLoS Pathog (2012) 1.01
Latent membrane protein 1 of Epstein-Barr virus induces CD83 by the NF-kappaB signaling pathway. J Virol (2003) 0.99
Epstein-Barr virus nuclear antigen 1 evades direct immune recognition by CD4+ T helper cells. Eur J Immunol (2004) 0.99
Functional analysis of Epstein-Barr virus SM protein: identification of amino acids essential for structure, transactivation, splicing inhibition, and virion production. J Virol (2004) 0.97
Toll-like receptor agonists synergistically increase proliferation and activation of B cells by epstein-barr virus. J Virol (2010) 0.97
The lytic phase of epstein-barr virus requires a viral genome with 5-methylcytosine residues in CpG sites. J Virol (2011) 0.95
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A virus-like particle-based Epstein-Barr virus vaccine. J Virol (2011) 0.92
Epstein-Barr virus and host cell methylation: regulation of latency, replication and virus reactivation. Curr Opin Virol (2013) 0.91
Epstein-Barr virus exploits BSAP/Pax5 to achieve the B-cell specificity of its growth-transforming program. J Virol (2007) 0.91
c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs. Nucleic Acids Res (2013) 0.90
The bZIP transcription factor MeaB mediates nitrogen metabolite repression at specific loci. Eukaryot Cell (2010) 0.87
EBV-gp350 confers B-cell tropism to tailored exosomes and is a neo-antigen in normal and malignant B cells--a new option for the treatment of B-CLL. PLoS One (2011) 0.85
HLA type-independent generation of antigen-specific T cells for adoptive immunotherapy. Eur J Immunol (2005) 0.85
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