PubRank

Masayasu Kojima

Author PubWeight™ 91.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion. Diabetes 2002 1.95
2 Weight loss increases circulating levels of ghrelin in human obesity. Clin Endocrinol (Oxf) 2002 1.76
3 Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: enteric distribution, ontogeny, influence of endocrine, and dietary manipulations. Endocrinology 2002 1.65
4 Molecular forms of hypothalamic ghrelin and its regulation by fasting and 2-deoxy-d-glucose administration. Endocrinology 2005 1.63
5 Hyperglycaemia suppresses the secretion of ghrelin, a novel growth-hormone-releasing peptide: responses to the intravenous and oral administration of glucose. Clin Sci (Lond) 2002 1.54
6 Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway. Nat Med 2004 1.48
7 Overexpression of human adiponectin in transgenic mice results in suppression of fat accumulation and prevention of premature death by high-calorie diet. Am J Physiol Endocrinol Metab 2007 1.48
8 Ghrelin directly regulates bone formation. J Bone Miner Res 2004 1.44
9 Gene expression, secretion, and autocrine action of C-type natriuretic peptide in cultured adult rat cardiac fibroblasts. Endocrinology 2003 1.40
10 Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin. Endocrinology 2005 1.38
11 Plasma ghrelin and desacyl ghrelin concentrations in renal failure. J Am Soc Nephrol 2002 1.37
12 International Union of Pharmacology. LVI. Ghrelin receptor nomenclature, distribution, and function. Pharmacol Rev 2005 1.35
13 Central control of bone remodeling by neuromedin U. Nat Med 2007 1.32
14 Biological, physiological, and pharmacological aspects of ghrelin. J Pharmacol Sci 2006 1.30
15 Structural divergence of human ghrelin. Identification of multiple ghrelin-derived molecules produced by post-translational processing. J Biol Chem 2002 1.30
16 Genomic structure and characterization of the 5'-flanking region of the human ghrelin gene. Endocrinology 2004 1.30
17 Ghrelin modulates the downstream molecules of insulin signaling in hepatoma cells. J Biol Chem 2001 1.28
18 Increased plasma ghrelin level in lung cancer cachexia. Clin Cancer Res 2003 1.27
19 The role of ghrelin and growth hormone secretagogues receptor on rat adipogenesis. Endocrinology 2003 1.19
20 Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin. Endocrinology 2002 1.19
21 Structure, regulation and function of ghrelin. J Biochem 2011 1.05
22 Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J 2005 1.02
23 The gut-brain peptide neuromedin U is involved in the mammalian circadian oscillator system. Biochem Biophys Res Commun 2004 0.98
24 Fasting plasma ghrelin levels are negatively correlated with insulin resistance and PAI-1, but not with leptin, in obese children and adolescents. Diabetes 2002 0.98
25 Ghrelin and the regulation of food intake and energy balance. Mol Interv 2002 0.95
26 Cardiovascular and hormonal effects of subcutaneous administration of ghrelin, a novel growth hormone-releasing peptide, in healthy humans. Clin Sci (Lond) 2003 0.94
27 Structures and molecular forms of the ghrelin-family peptides. Peptides 2011 0.94
28 A transient surge of ghrelin secretion before feeding is modified by different feeding regimens in sheep. Biochem Biophys Res Commun 2002 0.93
29 Ghrelin immunoreactivity in human plasma is suppressed by somatostatin. Clin Endocrinol (Oxf) 2002 0.92
30 Ghrelin O-acyltransferase (GOAT) has a preference for n-hexanoyl-CoA over n-octanoyl-CoA as an acyl donor. Biochem Biophys Res Commun 2009 0.92
31 The role of ghrelin and ghrelin-receptor gene variants and promoter activity in type 2 diabetes. Eur J Endocrinol 2009 0.91
32 Isolation of the bioactive peptides CCHamide-1 and CCHamide-2 from Drosophila and their putative role in appetite regulation as ligands for G protein-coupled receptors. Front Endocrinol (Lausanne) 2012 0.91
33 Maternal ghrelin plays an important role in rat fetal development during pregnancy. Endocrinology 2005 0.90
34 Analysis of rat insulin II promoter-ghrelin transgenic mice and rat glucagon promoter-ghrelin transgenic mice. J Biol Chem 2005 0.90
35 The neuropeptide neuromedin U promotes inflammation by direct activation of mast cells. J Exp Med 2005 0.90
36 Ghrelin directly stimulates adult hippocampal neurogenesis: implications for learning and memory. Endocr J 2013 0.89
37 Neuromedin U is involved in nociceptive reflexes and adaptation to environmental stimuli in mice. Biochem Biophys Res Commun 2004 0.89
38 Production of n-octanoyl-modified ghrelin in cultured cells requires prohormone processing protease and ghrelin O-acyltransferase, as well as n-octanoic acid. J Biochem 2009 0.88
39 Alteration of plasma ghrelin levels associated with the blood pressure in pregnancy. Hypertension 2002 0.88
40 Influencing the between-feeding and endocrine responses of plasma ghrelin in healthy dogs. Eur J Endocrinol 2005 0.87
41 Regulation of ghrelin secretion during pregnancy and lactation in the rat: possible involvement of hypothalamus. Peptides 2004 0.87
42 Characterization and species differences in gastric ghrelin cells from mice, rats and hamsters. J Anat 2004 0.86
43 Identification of the novel bioactive peptides dRYamide-1 and dRYamide-2, ligands for a neuropeptide Y-like receptor in Drosophila. Biochem Biophys Res Commun 2011 0.86
44 Chicken ghrelin: purification, cDNA cloning, and biological activity. Endocrinology 2002 0.86
45 Ghrelin and leptin: a link between obesity and allergy? J Allergy Clin Immunol 2006 0.85
46 Peptide purification, complementary deoxyribonucleic acid (DNA) and genomic DNA cloning, and functional characterization of ghrelin in rainbow trout. Endocrinology 2003 0.85
47 Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone attenuates inflammatory pain through the induction of heme oxygenase-1 in macrophages. Pain 2013 0.85
48 The neuropeptide neuromedin U activates eosinophils and is involved in allergen-induced eosinophilia. Am J Physiol Lung Cell Mol Physiol 2005 0.85
49 Involvement of cholinergic neurons in the regulation of the ghrelin secretory response to feeding in sheep. Biochem Biophys Res Commun 2003 0.84
50 Identification of tilapia ghrelin and its effects on growth hormone and prolactin release in the tilapia, Oreochromis mossambicus. Comp Biochem Physiol B Biochem Mol Biol 2003 0.84
51 Regulation of gonadotropin secretion and puberty onset by neuromedin U. FEBS Lett 2006 0.84
52 Ghrelin deficiency does not influence feeding performance. Regul Pept 2007 0.84
53 The neuropeptide neuromedin U promotes IL-6 production from macrophages and endotoxin shock. Biochem Biophys Res Commun 2006 0.83
54 Structural determination and histochemical localization of ghrelin in the red-eared slider turtle, Trachemys scripta elegans. Gen Comp Endocrinol 2004 0.82
55 Effect of chronic treatments with ghrelin on milk secretion in lactating rats. Biochem Biophys Res Commun 2003 0.82
56 Presynaptic modulation by neuromedin U of sensory synaptic transmission in rat spinal dorsal horn neurones. J Physiol 2004 0.82
57 Ghrelin is required for dietary restriction-induced enhancement of hippocampal neurogenesis: lessons from ghrelin knockout mice. Endocr J 2014 0.82
58 Parasporin-1, a novel cytotoxic protein from Bacillus thuringiensis, induces Ca2+ influx and a sustained elevation of the cytoplasmic Ca2+ concentration in toxin-sensitive cells. J Biol Chem 2007 0.82
59 Regional distribution and the dynamics of n-decanoyl ghrelin, another acyl-form of ghrelin, upon fasting in rodents. Regul Pept 2009 0.81
60 Factors associated with plasma ghrelin level in Japanese general population. Clin Endocrinol (Oxf) 2011 0.81
61 Identification of the endogenous cysteine-rich peptide trissin, a ligand for an orphan G protein-coupled receptor in Drosophila. Biochem Biophys Res Commun 2011 0.81
62 FABP3 and brown adipocyte-characteristic mitochondrial fatty acid oxidation enzymes are induced in beige cells in a different pathway from UCP1. Biochem Biophys Res Commun 2013 0.81
63 Effects of ghrelin on growth hormone secretion in vivo in ruminants. Regul Pept 2005 0.80
64 Ghrelin is involved in the decidualization of human endometrial stromal cells. J Clin Endocrinol Metab 2003 0.80
65 Purification and characterization of caprine ghrelin and its effect on growth hormone release. J Mol Neurosci 2010 0.80
66 Enzymatic characterization of GOAT, ghrelin O-acyltransferase. Methods Enzymol 2012 0.80
67 Immunohistochemical localization of ghrelin in rodent kidneys. Histochem Cell Biol 2006 0.80
68 Plasma levels of n-decanoyl ghrelin, another acyl- and active-form of ghrelin, in human subjects and the effect of glucose- or meal-ingestion on its dynamics. Regul Pept 2011 0.80
69 Developmental changes in the pattern of ghrelin's acyl modification and the levels of acyl-modified ghrelins in murine stomach. Endocrinology 2005 0.80
70 Ghrelin: a novel peptide for growth hormone release and feeding regulation. Curr Opin Clin Nutr Metab Care 2002 0.80
71 Peripheral administration of morphine attenuates postincisional pain by regulating macrophage polarization through COX-2-dependent pathway. Mol Pain 2014 0.80
72 The role of circulating ghrelin in growth hormone (GH) secretion in freely moving male rats. Life Sci 2003 0.79
73 Identification and functional analysis of a novel ligand for G protein-coupled receptor, Neuromedin S. Regul Pept 2007 0.79
74 Ghrelin expression in islet cell tumors: augmented expression of ghrelin in a case of glucagonoma with multiple endocrine neoplasm type I. J Clin Endocrinol Metab 2002 0.79
75 Effects of glucose and amino acids on ghrelin secretion in sheep. Anim Sci J 2010 0.79
76 Different effects of peripheral and central ghrelin on regulation of food intake in the Japanese quail. Gen Comp Endocrinol 2005 0.79
77 Changes in Subcellular Distribution of n-Octanoyl or n-Decanoyl Ghrelin in Ghrelin-Producing Cells. Front Endocrinol (Lausanne) 2013 0.79
78 Ghrelin acylation by ingestion of medium-chain fatty acids. Methods Enzymol 2012 0.78
79 Modulation by adiponectin of circadian clock rhythmicity in model mice for metabolic syndrome. Endocr J 2012 0.78
80 Effects of ghrelin on growth hormone secretion from cultured adenohypophysial cells in cattle. Endocr J 2003 0.78
81 Neuromedin U is necessary for normal gastrointestinal motility and is regulated by serotonin. Ann N Y Acad Sci 2010 0.78
82 Increased production of active ghrelin is relevant to hyperphagia in nonobese spontaneously diabetic Torii rats. Metabolism 2011 0.78
83 Purification, cDNA cloning, and characterization of ghrelin in channel catfish, Ictalurus punctatus. Gen Comp Endocrinol 2005 0.78
84 Ghrelin and leptin modulate immunity and liver function in overweight children. Pediatr Int 2009 0.77
85 Disrupted regulation of ghrelin production under antihypertensive treatment in spontaneously hypertensive rats. Circ J 2012 0.77
86 Ghrelin levels are reduced in Rett syndrome patients with eating difficulties. Int J Dev Neurosci 2011 0.77
87 Correction: The Nutrient-Responsive Hormone CCHamide-2 Controls Growth by Regulating Insulin-like Peptides in the Brain of Drosophila melanogaster. PLoS Genet 2015 0.77
88 Effects of intravenous ghrelin injection on plasma growth hormone, insulin and glucose concentrations in calves at weaning. Anim Sci J 2012 0.76
89 Ghrelin differentially modulates glucose-induced insulin secretion according to feeding status in sheep. J Endocrinol 2007 0.76
90 Production of ghrelin by the stomach of patients with gastric cancer. Kurume Med J 2014 0.76
91 Continuous antagonism of the ghrelin receptor results in early induction of salt-sensitive hypertension. J Mol Neurosci 2010 0.76
92 Isolation and characterization of a novel peptide, osteoblast activating peptide (OBAP), associated with osteoblast differentiation and bone formation. Biochem Biophys Res Commun 2010 0.75
93 The neuropeptide neuromedin U promotes autoantibody-mediated arthritis. Arthritis Res Ther 2012 0.75
94 A postweaning reduction in circulating ghrelin temporarily alters growth hormone (GH) responsiveness to GH-releasing hormone in male mice but does not affect somatic growth. Endocrinology 2010 0.75
95 The influence of feeding pattern on changes in plasma ghrelin in the Holstein cow. J Vet Med Sci 2014 0.75
96 Different distribution of neuromedin S and its mRNA in the rat brain: NMS peptide is present not only in the hypothalamus as the mRNA, but also in the brainstem. Front Endocrinol (Lausanne) 2012 0.75
97 Immunohistochemical localization and biochemical characterization of ghrelin in the brain and stomach of the frog Rana esculenta. J Comp Neurol 2002 0.75
98 Effects of amino acids infused into the vein on ghrelin-induced GH, insulin and glucagon secretion in lactating cows. Anim Sci J 2011 0.75
99 High-performance liquid chromatography analysis of hypothalamic ghrelin. Methods Enzymol 2012 0.75
100 Isolation and characterization of four VIP-related peptides from red-bellied newt, Cynops pyrrhogaster. Regul Pept 2004 0.75
101 [Discovery of ghrelin and its physiological significance]. Nihon Rinsho 2004 0.75