Published in Lancet Oncol on February 01, 2005
Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer. J Clin Oncol (2009) 10.18
Diabetes, metformin, and breast cancer in postmenopausal women. J Clin Oncol (2012) 3.47
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Diabetes mellitus and breast cancer outcomes: a systematic review and meta-analysis. J Clin Oncol (2010) 2.46
Metformin therapy and risk of cancer in patients with type 2 diabetes: systematic review. PLoS One (2013) 2.10
Impact of diabetes mellitus on complications and outcomes of adjuvant chemotherapy in older patients with breast cancer. J Clin Oncol (2009) 1.98
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Breast cancer chemoprevention: old and new approaches. J Biomed Biotechnol (2012) 1.57
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Comorbid disease and cancer: the need for more relevant conceptual models in health services research. J Clin Oncol (2005) 1.26
Obesity, insulin resistance and cancer risk. Yonsei Med J (2005) 1.20
Association between metformin therapy and mortality after breast cancer: a population-based study. Diabetes Care (2013) 1.15
Diabetes and prognosis in a breast cancer cohort. J Cancer Res Clin Oncol (2010) 1.14
The impact of type 2 diabetes and antidiabetic drugs on cancer cell growth. J Cell Mol Med (2011) 1.12
Diabetes and cancer: two diseases with obesity as a common risk factor. Diabetes Obes Metab (2013) 1.11
Diabetes and cancer I: risk, survival, and implications for screening. Cancer Causes Control (2012) 1.04
Cancer risk in HBV patients with statin and metformin use: a population-based cohort study. Medicine (Baltimore) (2015) 1.02
Pregnancy characteristics and maternal breast cancer risk: a review of the epidemiologic literature. Cancer Causes Control (2010) 1.01
Comparative safety of cardiovascular medication use and breast cancer outcomes among women with early stage breast cancer. Breast Cancer Res Treat (2014) 1.01
Glucose promotes breast cancer aggression and reduces metformin efficacy. Cell Cycle (2013) 0.99
Diabetes mellitus increases the risk of bladder cancer: an updated meta-analysis of observational studies. Diabetes Technol Ther (2013) 0.98
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Diabetes mellitus and hepatocellular carcinoma: comparison of Chinese patients with and without HBV-related cirrhosis. World J Gastroenterol (2010) 0.89
Metformin: A candidate for the treatment of gynecological tumors based on drug repositioning. Oncol Lett (2016) 0.89
Metabolic syndrome and outcomes following early-stage breast cancer. Breast Cancer Res Treat (2014) 0.88
Relationship between diabetes and risk of second primary contralateral breast cancer. Breast Cancer Res Treat (2010) 0.86
Long-term use of metformin and the molecular subtype in invasive breast carcinoma patients - a retrospective study of clinical and tumor characteristics. BMC Cancer (2014) 0.84
Differential expression and signaling activation of insulin receptor isoforms A and B: A link between breast cancer and diabetes. Growth Factors (2011) 0.84
Diabetes, diabetes treatment and breast cancer prognosis. Breast Cancer Res Treat (2014) 0.84
Blood glucose concentrations and breast cancer risk in women without diabetes: a meta-analysis. Eur J Nutr (2012) 0.83
Association between diabetes, diabetes treatment and risk of developing endometrial cancer. Br J Cancer (2014) 0.83
Pregnancy-related characteristics and breast cancer risk. Cancer Causes Control (2013) 0.83
Cancer risk in type 2 diabetes mellitus: metabolic links and therapeutic considerations. J Nutr Metab (2011) 0.83
LIP expression is regulated by IGF-1R signaling and participates in suppression of anoikis. Mol Cancer (2011) 0.83
Cardiometabolic factors and breast cancer risk in U.S. black women. Breast Cancer Res Treat (2012) 0.82
Study Protocol: insulin and its role in cancer. BMC Endocr Disord (2007) 0.81
Adipose microenvironment promotes triple negative breast cancer cell invasiveness and dissemination by producing CCL5. Oncotarget (2016) 0.81
Epidemiology and outcomes of previously undiagnosed diabetes in older women with breast cancer: an observational cohort study based on SEER-Medicare. BMC Cancer (2012) 0.81
Selection criteria for hepatectomy in patients with hepatocellular carcinoma classified as Child-Pugh class B. World J Surg (2011) 0.79
Associations between Diabetes and Quality of Life among Breast Cancer Survivors. PLoS One (2016) 0.79
Detection of expressional changes induced by intrauterine growth restriction in the developing rat mammary gland via exploratory pathways analysis. PLoS One (2014) 0.79
Insulin glargine versus other types of basal insulin-clinical and tumor characteristics in patients with breast carcinoma. BMC Res Notes (2013) 0.79
The evaluation of the association between the metabolic syndrome and tumor grade and stage of bladder cancer in a Chinese population. Onco Targets Ther (2016) 0.79
The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat (2012) 0.78
Diabetes and prostate cancer screening in black and white men. Cancer Causes Control (2013) 0.78
Mammography use among women with and without diabetes: results from the Southern Community Cohort Study. J Epidemiol Glob Health (2014) 0.78
ADRB2 G-G haplotype associated with breast cancer risk among Hispanic and non-Hispanic white women: interaction with type 2 diabetes and obesity. Cancer Causes Control (2012) 0.78
Undiagnosed diabetes in breast, colorectal, lung, and prostate cancer: incidence and risk factors. ISRN Oncol (2014) 0.78
2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications. Oncotarget (2017) 0.77
Obesity, diabetes mellitus, and the risk of female breast cancer in Eastern China. World J Surg Oncol (2013) 0.77
On the status and comparison of glucose intolerance in female breast cancer patients at initial diagnosis and during chemotherapy through an oral glucose tolerance test. PLoS One (2014) 0.77
Type 2 diabetes and mammographic breast density among underserved women. Cancer Causes Control (2014) 0.77
The double trouble of metabolic diseases: the diabetes-cancer link. Mol Biol Cell (2015) 0.76
Diabetes and breast cancer mortality in Black women. Cancer Causes Control (2016) 0.75
Expression of Intratumoral IGF-II Is Regulated by the Gene Imprinting Status in Triple Negative Breast Cancer from Vietnamese Patients. Int J Endocrinol (2015) 0.75
Comparative safety of diabetes medications and risk of incident invasive breast cancer: a population-based cohort study. Cancer Causes Control (2016) 0.75
Gestational diabetes mellitus may be associated with increased risk of breast cancer. Br J Cancer (2017) 0.75
Diabetes mellitus and prognosis in women with breast cancer: A systematic review and meta-analysis. Medicine (Baltimore) (2016) 0.75
Pre-Existing Diabetes in Early Stage Breast Cancer Patients is Associated with Lack of Improvement in Quality of Life 2 Years After Diagnosis. Int J Behav Med (2016) 0.75
Convergence and divergence of genetic and modular networks between diabetes and breast cancer. J Cell Mol Med (2015) 0.75
Associations between diabetes medication use and risk of second breast cancer events and mortality. Cancer Causes Control (2015) 0.75
Comparative Effect of Initiating Metformin Versus Sulfonylureas on Breast Cancer Risk in Older Women. Epidemiology (2017) 0.75
Unexploited Antineoplastic Effects of Commercially Available Anti-Diabetic Drugs. Pharmaceuticals (Basel) (2016) 0.75
Sansevieria roxburghiana Schult. & Schult. F. (Family: Asparagaceae) Attenuates Type 2 Diabetes and Its Associated Cardiomyopathy. PLoS One (2016) 0.75
Metformin therapy and the risk of colorectal adenoma in patients with type 2 diabetes: A meta-analysis. Oncotarget (2016) 0.75
Use of noninsulin anti diabetics for prevention and treatment of cancer- narrative review article. Iran J Public Health (2015) 0.75
Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med (2006) 17.08
Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet (2002) 9.48
Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial. JAMA (2003) 8.47
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population. Nat Genet (2010) 4.96
A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses. Breast Cancer Res Treat (2008) 4.84
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone. Diabetes Care (2006) 4.75
Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Cancer (2008) 3.98
Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer. JAMA (2012) 3.85
Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer. J Clin Oncol (2008) 3.46
Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Am J Hum Genet (2008) 3.41
Clinical responses in a phase II study using adoptive transfer of short-term cultured tumor infiltration lymphocytes in metastatic melanoma patients. Clin Cancer Res (2010) 3.02
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genet (2013) 2.39
Nasal intermittent mandatory ventilation versus nasal continuous positive airway pressure for respiratory distress syndrome: a randomized, controlled, prospective study. J Pediatr (2007) 2.36
The INTERPHONE study: design, epidemiological methods, and description of the study population. Eur J Epidemiol (2007) 2.30
Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers. Hum Mol Genet (2009) 2.13
Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population. Proc Natl Acad Sci U S A (2006) 1.99
Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells. Proc Natl Acad Sci U S A (2005) 1.93
Genetic predisposition for the development of radiation-associated meningioma: an epidemiological study. Lancet Oncol (2007) 1.92
Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction. Cancer Res (2010) 1.90
Progression of normotensive adolescents to hypertensive adults: a study of 26,980 teenagers. Hypertension (2010) 1.87
Pain palliation in patients with bone metastases using MR-guided focused ultrasound surgery: a multicenter study. Ann Surg Oncol (2008) 1.85
Randomized phase II study of the anti-epidermal growth factor receptor monoclonal antibody cetuximab with cisplatin versus cisplatin alone in patients with metastatic triple-negative breast cancer. J Clin Oncol (2013) 1.79
Phase II study of predictive biomarker profiles for response targeting human epidermal growth factor receptor 2 (HER-2) in advanced inflammatory breast cancer with lapatinib monotherapy. J Clin Oncol (2008) 1.78
The tinea capitis campaign in Serbia in the 1950s. Lancet Infect Dis (2010) 1.57
Pregnancy-associated breast cancer. Isr Med Assoc J (2008) 1.53
Treatment with 9-cis β-carotene-rich powder in patients with retinitis pigmentosa: a randomized crossover trial. JAMA Ophthalmol (2013) 1.53
Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers. Hum Mol Genet (2011) 1.51
GLIOGENE an International Consortium to Understand Familial Glioma. Cancer Epidemiol Biomarkers Prev (2007) 1.42
Adjuvant chemotherapy and whole abdominal irradiation for gastric carcinoma. Tumori (2008) 1.39
The Glioma International Case-Control Study: A Report From the Genetic Epidemiology of Glioma International Consortium. Am J Epidemiol (2015) 1.27
A phase II study of Imatinib for advanced adenoid cystic carcinoma of head and neck salivary glands. Oral Oncol (2006) 1.26
Issues of diagnostic review in brain tumor studies: from the Brain Tumor Epidemiology Consortium. Cancer Epidemiol Biomarkers Prev (2008) 1.25
Minimally cultured or selected autologous tumor-infiltrating lymphocytes after a lympho-depleting chemotherapy regimen in metastatic melanoma patients. J Immunother (2009) 1.25
Time trends of incidence rates of thyroid cancer in Israel: what might explain the sharp increase. Thyroid (2006) 1.20
Randomized phase II study of lapatinib plus capecitabine or lapatinib plus topotecan for patients with HER2-positive breast cancer brain metastases. J Neurooncol (2011) 1.17
The implementation of managed care for diabetes using medical informatics in a large Preferred Provider Organization. Diabetes Res Clin Pract (2005) 1.15
Uterine leiomyosarcoma: does the primary surgical procedure matter? Int J Gynecol Cancer (2009) 1.14
Adiponectin, ghrelin, and leptin in cancer cachexia in breast and colon cancer patients. Cancer (2006) 1.13
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. PLoS Biol (2011) 1.12
Local therapy in BRCA1 and BRCA2 mutation carriers with operable breast cancer: comparison of breast conservation and mastectomy. Breast Cancer Res Treat (2010) 1.10
Neoadjuvant imatinib for unresectable gastrointestinal stromal tumor. Anticancer Drugs (2004) 1.10
Follow-up of ovarian and primary peritoneal carcinoma: the value of physical examination in patients with pretreatment elevated CA125 levels. Gynecol Oncol (2006) 1.10
Comparison between primary peritoneal and epithelial ovarian carcinoma: a population-based study. Am J Obstet Gynecol (2004) 1.09
KL1 internal repeat mediates klotho tumor suppressor activities and inhibits bFGF and IGF-I signaling in pancreatic cancer. Clin Cancer Res (2011) 1.07
Genome-wide high-density SNP linkage search for glioma susceptibility loci: results from the Gliogene Consortium. Cancer Res (2011) 1.05
Allergy and brain tumors in the INTERPHONE study: pooled results from Australia, Canada, France, Israel, and New Zealand. Cancer Causes Control (2013) 1.05
Association between diabetes mellitus and adverse characteristics of breast cancer at presentation. Eur J Cancer (2006) 1.04
A pooled analysis of thyroid cancer incidence following radiotherapy for childhood cancer. Radiat Res (2012) 1.03
Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev (2010) 1.01
Smoking and risk of glioma: a meta-analysis. Cancer Causes Control (2009) 1.00
Efficacy of chemotherapy in BRCA1/2 mutation carrier ovarian cancer in the setting of PARP inhibitor resistance: a multi-institutional study. Clin Cancer Res (2013) 0.99
p38 mitogen-activated protein kinase-dependent transactivation of ErbB receptor family: a novel common mechanism for stress-induced IRS-1 serine phosphorylation and insulin resistance. Diabetes (2011) 0.98
First-line bevacizumab-containing therapy for triple-negative breast cancer: analysis of 585 patients treated in the ATHENA study. Oncology (2012) 0.96
Using time-dependent covariate analysis to elucidate the relation of smoking history to Warthin's tumor risk. Am J Epidemiol (2009) 0.96
Quantifying the impact of selection bias caused by nonparticipation in a case-control study of mobile phone use. Ann Epidemiol (2009) 0.95
Parametric diffusion tensor imaging of the breast. Invest Radiol (2012) 0.94
The sequence of vessel interruption during lobectomy for non-small cell lung cancer: is it indeed important? J Thorac Cardiovasc Surg (2003) 0.93
Motivation for giving birth after breast cancer. Psychooncology (2005) 0.93
Association between standard clinical and pathologic characteristics and the 21-gene recurrence score in breast cancer patients: a population-based study. Cancer (2008) 0.93
Incomplete response to colchicine in M694V homozygote FMF patients. Autoimmun Rev (2012) 0.93
Excess lifetime cancer mortality risk attributed to radiation exposure from pediatric computed tomography scan. Isr Med Assoc J (2007) 0.92
Successful pregnancy after unilateral adrenalectomy in a case of primary pigmented adrenocortical disease. J Matern Fetal Neonatal Med (2005) 0.92
The peptide-hormone glucagon-like peptide-1 activates cAMP and inhibits growth of breast cancer cells. Breast Cancer Res Treat (2011) 0.91
Timing of sentinel lymph node biopsy in patients receiving neoadjuvant chemotherapy for breast cancer. J Surg Oncol (2008) 0.91
Epigenetic silencing of the tumor suppressor klotho in human breast cancer. Breast Cancer Res Treat (2011) 0.90
Offspring gender ratio and the rate of recurrent spontaneous miscarriages in jewish women at high risk for breast/ovarian cancer. Am J Hum Genet (2004) 0.90
Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers. Hum Mol Genet (2011) 0.89
The RNF146 and ECHDC1 genes as candidates for inherited breast and ovarian cancer in Jewish Ashkenazi women. Fam Cancer (2009) 0.89
A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev (2012) 0.89
Transactivation of ErbB2 and ErbB3 by tumor necrosis factor-alpha and anisomycin leads to impaired insulin signaling through serine/threonine phosphorylation of IRS proteins. J Biol Chem (2002) 0.88
Adjuvant radiotherapy for thymic epithelial tumor: treatment results and prognostic factors. Am J Clin Oncol (2007) 0.87
The acute effect of various glycemic index dietary carbohydrates on endothelial function in nondiabetic overweight and obese subjects. J Am Coll Cardiol (2009) 0.87
Germline mutations in BRCA1 and BRCA2 genes in ethnically diverse high risk families in Israel. Breast Cancer Res Treat (2010) 0.86
High rates of substance abuse among long-term travelers to the tropics: an interventional study. J Travel Med (2004) 0.86
Perfusion-weighted imaging of peritumoral edema can aid in the differential diagnosis of glioblastoma mulltiforme versus brain metastasis. Isr Med Assoc J (2013) 0.86
Possible interaction between ionizing radiation, smoking, and gender in the causation of meningioma. Neuro Oncol (2011) 0.85
Continuous noninvasive glucose monitoring technology based on "occlusion spectroscopy". J Diabetes Sci Technol (2007) 0.85
Alendronate for osteoporosis in men with androgen-repleted hypogonadism. Osteoporos Int (2005) 0.84
The sequence of vessel interruption during lobectomy: does it affect the amount of blood retained in the lobe? Eur J Cardiothorac Surg (2007) 0.84
Challenges to the development of new agents for molecularly defined patient subsets: lessons from BRCA1/2-associated breast cancer. J Clin Oncol (2011) 0.84
Concurrent chemobiotherapy with cisplatin, dacarbazine, decrescendo interleukin-2 and interferon alpha2b in patients with metastatic melanoma. Oncol Rep (2008) 0.84
A phase II study of oral UFT and leucovorin concurrently with pelvic irradiation as neoadjuvant chemoradiation for rectal cancer. Anticancer Res (2007) 0.83
Indications of possible brain-tumour risk in mobile-phone studies: should we be concerned? Occup Environ Med (2011) 0.83
A variable age of onset segregation model for linkage analysis, with correction for ascertainment, applied to glioma. Cancer Epidemiol Biomarkers Prev (2012) 0.83
Analysis of BRCA1/BRCA2 genes' contribution to breast cancer susceptibility in high risk Jewish Ashkenazi women. Fam Cancer (2008) 0.83
The additional dose to radiosensitive organs caused by using under-collimated X-ray beams in neonatal intensive care radiography. Radiat Prot Dosimetry (2008) 0.83
INTEROCC case-control study: lack of association between glioma tumors and occupational exposure to selected combustion products, dusts and other chemical agents. BMC Public Health (2013) 0.82
Nonpenetrating deep sclerectomy with the use of adjunctive mitomycin C. Ophthalmic Surg Lasers Imaging (2004) 0.82
A single Mediterranean, possibly Jewish, origin for the Val59Gly CDKN2A mutation in four melanoma-prone families. Eur J Hum Genet (2003) 0.82
Efficacy of liraglutide in a real-life cohort. Diabetes Ther (2014) 0.82