Published in J Biol Chem on February 01, 2005
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. J Cell Biol (2005) 2.57
Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis. J Cell Biol (2005) 1.85
Translational control by cytoplasmic polyadenylation in Xenopus oocytes. Biochim Biophys Acta (2008) 1.85
Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules. J Cell Biol (2005) 1.70
Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability. J Cell Biol (2010) 1.22
Differential phosphorylation controls Maskin association with eukaryotic translation initiation factor 4E and localization on the mitotic apparatus. Mol Cell Biol (2005) 1.15
Transforming acidic coiled-coil 3 and Aurora-A interact in human thyrocytes and their expression is deregulated in thyroid cancer tissues. Endocr Relat Cancer (2007) 0.90
TACC3 promotes stemness and is a potential therapeutic target in hepatocellular carcinoma. Oncotarget (2015) 0.90
Translational control of maskin mRNA by its 3' untranslated region. Biol Cell (2007) 0.86
Chromosome 4p16.3 variant modify bladder cancer risk in a Chinese population. Carcinogenesis (2011) 0.86
Novel functions of endocytic player clathrin in mitosis. Cell Res (2011) 0.85
Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes. J Biol Chem (2009) 0.84
A translational regulator, PUM2, promotes both protein stability and kinase activity of Aurora-A. PLoS One (2011) 0.84
Mechanistic studies of the mitotic activation of Mos. Mol Cell Biol (2006) 0.84
Issues in interpreting the in vivo activity of Aurora-A. Expert Opin Ther Targets (2014) 0.80
A Cell Biologist's Field Guide to Aurora Kinase Inhibitors. Front Oncol (2015) 0.80
Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly. PLoS Genet (2015) 0.80
Tousled-mediated activation of Aurora B kinase does not require Tousled kinase activity in vivo. J Biol Chem (2008) 0.79
HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle. Nature (2012) 3.08
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. J Cell Biol (2002) 3.05
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nat Cell Biol (2003) 2.86
Aurora kinases, aneuploidy and cancer, a coincidence or a real link? Trends Cell Biol (2005) 2.41
Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition. J Cell Sci (2004) 1.93
On the role of aurora-A in centrosome function. Oncogene (2002) 1.68
Inhibition of endothelial cell apoptosis by netrin-1 during angiogenesis. Dev Cell (2009) 1.50
The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation. EMBO Rep (2006) 1.49
APC/Fizzy-Related targets Aurora-A kinase for proteolysis. EMBO Rep (2002) 1.45
TACC1-chTOG-Aurora A protein complex in breast cancer. Oncogene (2003) 1.33
PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores. J Cell Biol (2007) 1.27
Spindle pole regulation by a discrete Eg5-interacting domain in TPX2. Curr Biol (2008) 1.26
CDC25B phosphorylation by Aurora-A occurs at the G2/M transition and is inhibited by DNA damage. Cell Cycle (2005) 1.18
Proteomic investigation of phosphorylation sites in poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase. J Proteome Res (2009) 1.14
Glypican-1 is a vehicle for polyamine uptake in mammalian cells: a pivital role for nitrosothiol-derived nitric oxide. J Biol Chem (2003) 1.14
Netrin-1 up-regulation in inflammatory bowel diseases is required for colorectal cancer progression. Proc Natl Acad Sci U S A (2009) 1.13
FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients. Cell Div (2007) 1.13
The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A. EMBO Rep (2002) 1.09
Aurora B -TACC1 protein complex in cytokinesis. Oncogene (2004) 1.07
Spatio-temporal expression patterns of aurora kinases a, B, and C and cytoplasmic polyadenylation-element-binding protein in bovine oocytes during meiotic maturation. Biol Reprod (2007) 1.04
Centrosome separation: respective role of microtubules and actin filaments. Biol Cell (2002) 1.04
Aurora A is involved in central spindle assembly through phosphorylation of Ser 19 in P150Glued. J Cell Biol (2013) 1.02
Retro hydrazino-azapeptoids as peptidomimetics of proteasome inhibitors. J Med Chem (2005) 1.00
Effects of the Aurora kinase inhibitor VX-680 on anaplastic thyroid cancer-derived cell lines. Endocr Relat Cancer (2008) 0.97
A Drosophila model to identify polyamine-drug conjugates that target the polyamine transporter in an intact epithelium. J Med Chem (2007) 0.97
Expression of Aurora kinases in human thyroid carcinoma cell lines and tissues. Int J Cancer (2006) 0.96
Cdk1, Plks, Auroras, and Neks: the mitotic bodyguards. Adv Exp Med Biol (2008) 0.96
ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis. Hum Mol Genet (2007) 0.95
Nucleophosmin/B23 activates Aurora A at the centrosome through phosphorylation of serine 89. J Cell Biol (2012) 0.95
Localization of aurora A and aurora B kinases during interphase: role of the N-terminal domain. Cell Cycle (2008) 0.95
Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis. J Clin Invest (2010) 0.94
Phosphorylation of histone and histone-like proteins by aurora kinases during mitosis. Prog Cell Cycle Res (2003) 0.93
Defining the molecular requirements for the selective delivery of polyamine conjugates into cells containing active polyamine transporters. J Med Chem (2003) 0.92
Transforming acidic coiled-coil 3 and Aurora-A interact in human thyrocytes and their expression is deregulated in thyroid cancer tissues. Endocr Relat Cancer (2007) 0.90
Overexpression of active Aurora-C kinase results in cell transformation and tumour formation. PLoS One (2011) 0.90
Cdc2-cyclin B triggers H3 kinase activation of Aurora-A in Xenopus oocytes. J Biol Chem (2003) 0.90
The absence of p53 aggravates polyploidy and centrosome number abnormality induced by Aurora-C overexpression. Cell Cycle (2005) 0.90
ASAP, a human microtubule-associated protein required for bipolar spindle assembly and cytokinesis. Proc Natl Acad Sci U S A (2005) 0.90
F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system. Cancer Res (2008) 0.89
N1-substituent effects in the selective delivery of polyamine conjugates into cells containing active polyamine transporters. J Med Chem (2004) 0.88
Aurora-A kinase Ser349 phosphorylation is required during Xenopus laevis oocyte maturation. Dev Biol (2008) 0.88
CDK11(p58) is required for centriole duplication and Plk4 recruitment to mitotic centrosomes. PLoS One (2011) 0.88
Regulation of the Aurora-A gene following topoisomerase I inhibition: implication of the Myc transcription factor. Mol Cancer (2010) 0.87
Molecular requirements for targeting the polyamine transport system. Synthesis and biological evaluation of polyamine-anthracene conjugates. J Med Chem (2003) 0.87
Histologic prognostic factors associated with chromosomal imbalances in a contemporary series of 89 clear cell renal cell carcinomas. Hum Pathol (2013) 0.86
Dynactin targets Pavarotti-KLP to the central spindle during anaphase and facilitates cytokinesis in Drosophila S2 cells. J Cell Sci (2006) 0.85
Aurora-C interacts with and phosphorylates the transforming acidic coiled-coil 1 protein. Biochem Biophys Res Commun (2011) 0.84
Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes. J Biol Chem (2009) 0.84
Synthesis and cytotoxic activities of usnic acid derivatives. Bioorg Med Chem (2008) 0.83
Atmospheric pressure chemical ionization-mass spectrometry method to improve the determination of dansylated polyamines. Anal Biochem (2003) 0.83
A comparison of chloroambucil- and xylene-containing polyamines leads to improved ligands for accessing the polyamine transport system. J Med Chem (2008) 0.83
Aurora kinases are expressed in medullary thyroid carcinoma (MTC) and their inhibition suppresses in vitro growth and tumorigenicity of the MTC derived cell line TT. BMC Cancer (2011) 0.83
All anti-vascular endothelial growth factor drugs can induce 'pre-eclampsia-like syndrome': a RARe study. Nephrol Dial Transplant (2013) 0.82
A SUMOylation Motif in Aurora-A: Implications for Spindle Dynamics and Oncogenesis. Front Oncol (2011) 0.82
Staphylococcus aureus-induced G2/M phase transition delay in host epithelial cells increases bacterial infective efficiency. PLoS One (2013) 0.82
Sonic Hedgehog promotes tumor cell survival by inhibiting CDON pro-apoptotic activity. PLoS Biol (2013) 0.82
Preparation and characterization of a human aurora-A kinase monoclonal antibody. Mol Cell Biochem (2003) 0.81
Ca2+ homeostasis regulates Xenopus oocyte maturation. Biol Reprod (2007) 0.81
Polyamine modulation of iron uptake in CHO cells. Biochem Pharmacol (2004) 0.80
Synthesis and biological evaluation of N1-(anthracen-9-ylmethyl)triamines as molecular recognition elements for the polyamine transporter. J Med Chem (2003) 0.80
Identification of the leukemia inhibitory factor cell targets within the rat testis. Biol Reprod (2004) 0.80
Cytotoxic activity of compounds from the lichen: Cladonia convoluta. Planta Med (2004) 0.80
A Method for Analyzing the Ubiquitination and Degradation of Aurora-A. Biol Proced Online (2002) 0.80
Identification of pVHL as a novel substrate for Aurora-A in clear cell renal cell carcinoma (ccRCC). PLoS One (2013) 0.80
Identification of ILK as a new partner of the ADAM12 disintegrin and metalloprotease in cell adhesion and survival. Mol Biol Cell (2012) 0.79
The Protein Kinase Resource: everything you always wanted to know about protein kinases but were afraid to ask. Biol Cell (2005) 0.79
Inhibition of the aurora kinases suppresses in vitro NT2-D1 cell growth and tumorigenicity. J Endocrinol (2009) 0.79
Several signaling pathways are involved in the control of cattle oocyte maturation. Mol Reprod Dev (2004) 0.78
MNK1 kinase activity is required for abscission. J Cell Sci (2012) 0.78
[Angiotensin-2 type 1 receptors (AT1R) and cancers]. Nephrol Ther (2013) 0.78
The subcellular localization of cyclin B2 is required for bipolar spindle formation during Xenopus oocyte maturation. Biochem Biophys Res Commun (2012) 0.78
Antioxidative properties of natural polyamines and dimethylsilane analogues. Redox Rep (2005) 0.78
Aurora-A overexpression leads to override of the microtubule-kinetochore attachment checkpoint. Mol Interv (2003) 0.78
(Z)-1,4-diamino-2-butene as a vector of boron, fluorine, or iodine for cancer therapy and imaging: synthesis and biological evaluation. Bioorg Med Chem (2002) 0.78
Clockwise or anticlockwise? Turning the centriole triplets in the right direction! FEBS Lett (2007) 0.78
Synthesis and biological evaluation of dihydromotuporamine derivatives in cells containing active polyamine transporters. J Med Chem (2005) 0.77
Aurora A overexpression and pVHL reduced expression are correlated with a bad kidney cancer prognosis. Dis Markers (2012) 0.77
Assessment of Aurora A kinase expression in breast cancer: a tool for early diagnosis? Dis Markers (2013) 0.77
Epithelial cell division in the Xenopus laevis embryo during gastrulation. Int J Dev Biol (2014) 0.77
Cell cycle. A trigger for centrosome duplication. Science (2002) 0.77
Designing the polyamine pharmacophore: influence of N-substituents on the transport behavior of polyamine conjugates. J Med Chem (2008) 0.77
Water-soluble nickel-bis(dithiolene) complexes as photothermal agents. Chem Commun (Camb) (2015) 0.77
Hydrazino-aza and N-azapeptoids with therapeutic potential as anticancer agents. Bioorg Med Chem (2003) 0.76
Immunohistochemical analysis of tumor polyamines discriminates high-risk patients undergoing nephrectomy for renal cell carcinoma. Hum Pathol (2004) 0.76