Published in Oncogene on February 03, 2005
Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction. J Biol Chem (2008) 2.53
Proteoglycans in cancer biology, tumour microenvironment and angiogenesis. J Cell Mol Med (2011) 2.21
Proteoglycan form and function: A comprehensive nomenclature of proteoglycans. Matrix Biol (2015) 1.91
Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans. FEBS J (2010) 1.82
Decorin is a novel antagonistic ligand of the Met receptor. J Cell Biol (2009) 1.76
Decorin: a guardian from the matrix. Am J Pathol (2012) 1.46
An antimetastatic role for decorin in breast cancer. Am J Pathol (2008) 1.34
Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels. J Biol Chem (2010) 1.32
Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation. Carcinogenesis (2008) 1.28
Decorin causes autophagy in endothelial cells via Peg3. Proc Natl Acad Sci U S A (2013) 1.22
Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling. J Biol Chem (2011) 1.21
Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3. J Biol Chem (2011) 1.20
Role of decorin in the antimyeloma effects of osteoblasts. Blood (2008) 1.19
Comparative mRNA and microRNA expression profiling of three genitourinary cancers reveals common hallmarks and cancer-specific molecular events. PLoS One (2011) 1.15
Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice. Carcinogenesis (2011) 1.10
Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model. PLoS One (2012) 1.09
Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies. Breast Cancer Res (2008) 1.04
Differential expression of decorin by human malignant and benign vascular tumors. J Histochem Cytochem (2008) 1.04
Proteoglycans in prostate cancer. Nat Rev Urol (2012) 0.99
Mechanisms of ErbB receptor negative regulation and relevance in cancer. Exp Cell Res (2008) 0.99
Decorin deficiency promotes hepatic carcinogenesis. Matrix Biol (2013) 0.97
Dichotomy of decorin activity on the insulin-like growth factor-I system. FEBS J (2013) 0.96
A central role for decorin during vertebrate convergent extension. J Biol Chem (2009) 0.93
Osteoblastogenesis and tumor growth in myeloma. Leuk Lymphoma (2010) 0.93
Insights into the key roles of proteoglycans in breast cancer biology and translational medicine. Biochim Biophys Acta (2015) 0.92
Integrated proteomic, transcriptomic, and biological network analysis of breast carcinoma reveals molecular features of tumorigenesis and clinical relapse. Mol Cell Proteomics (2012) 0.92
Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer. FEBS J (2014) 0.92
Expression of the metastasis suppressor KAI1 in decidual cells at the human maternal-fetal interface: Regulation and functional implications. Am J Pathol (2007) 0.91
Differential expression of decorin, EGFR and cyclin D1 during mammary gland carcinogenesis in TA2 mice with spontaneous breast cancer. J Exp Clin Cancer Res (2010) 0.90
Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis. FEBS J (2013) 0.89
Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin. J Biol Chem (2014) 0.89
Localization of decorin gene expression in normal human breast tissue and in benign and malignant tumors of the human breast. Histochem Cell Biol (2012) 0.88
Growth factors in tumor microenvironment. Front Biosci (Landmark Ed) (2010) 0.88
Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells. Matrix Biol (2014) 0.88
Decorin regulates endothelial cell-matrix interactions during angiogenesis. Cell Adh Migr (2009) 0.86
Biglycan and decorin differentially regulate signaling in the fetal membranes. Matrix Biol (2013) 0.85
Recombinant human decorin suppresses liver HepG2 carcinoma cells by p21 upregulation. Onco Targets Ther (2012) 0.84
HER-2/neu-mediated down-regulation of biglycan associated with altered growth properties. J Biol Chem (2012) 0.84
Endocan-expressing microvessel density as a prognostic factor for survival in human gastric cancer. World J Gastroenterol (2016) 0.83
Biological functions of decorin in cancer. Chin J Cancer (2013) 0.83
Breast carcinoma cells in primary tumors and effusions have different gene array profiles. J Oncol (2009) 0.83
Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases. Hum Gene Ther (2015) 0.83
Periostin suppression induces decorin secretion leading to reduced breast cancer cell motility and invasion. Sci Rep (2014) 0.82
Correlation between expression and differentiation of endocan in colorectal cancer. World J Gastroenterol (2008) 0.82
Decorin as a multivalent therapeutic agent against cancer. Adv Drug Deliv Rev (2015) 0.82
The motile breast cancer phenotype roles of proteoglycans/glycosaminoglycans. Biomed Res Int (2014) 0.80
Lack of decorin expression by human bladder cancer cells offers new tools in the therapy of urothelial malignancies. PLoS One (2013) 0.79
Angiocidin inhibits breast cancer proliferation through activation of epidermal growth factor receptor and nuclear factor kappa (NF-ĸB). Exp Mol Pathol (2011) 0.79
Decorin induced by progesterone plays a crucial role in suppressing endometriosis. J Endocrinol (2014) 0.78
Prognostic value of stromal decorin expression in patients with breast cancer: a meta-analysis. J Thorac Dis (2015) 0.78
Decorin protects human hepatoma HepG2 cells against oxygen-glucose deprivation via modulating autophagy. Int J Clin Exp Med (2015) 0.78
Extracellular matrix macromolecules: potential tools and targets in cancer gene therapy. Mol Cell Ther (2014) 0.78
MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar. PLoS One (2015) 0.78
Oncosuppressive functions of decorin. Mol Cell Oncol (2015) 0.78
Effects of promoter leakage on dynamics of gene expression. BMC Syst Biol (2015) 0.78
Neoplastic transformation of ciliary body epithelium is associated with loss of opticin expression. Br J Ophthalmol (2006) 0.77
Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells. Matrix Biol (2014) 0.77
Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology. FEBS J (2016) 0.76
Utilization of Glycosaminoglycans/Proteoglycans as Carriers for Targeted Therapy Delivery. Int J Cell Biol (2015) 0.76
The expression of syndecan-1, syndecan-4 and decorin in healthy human breast tissue during the menstrual cycle. Reprod Biol Endocrinol (2010) 0.76
Extracellular Matrix, a Hard Player in Angiogenesis. Int J Mol Sci (2016) 0.75
Mechanistic and therapeutic overview of glycosaminoglycans: the unsung heroes of biomolecular signaling. Glycoconj J (2015) 0.75
Compensatory fetal membrane mechanisms between biglycan and decorin in inflammation. Mol Reprod Dev (2015) 0.75
Antiangiogenic mechanisms and factors in breast cancer treatment. J Carcinog (2016) 0.75
Expression of decorin in intestinal tissues of mice with inflammatory bowel disease and its correlation with autophagy. Exp Ther Med (2016) 0.75
Decorin gene upregulation mediated by an adeno-associated virus vector increases intratumoral uptake of nab-paclitaxel in neuroblastoma via inhibition of stabilin-1. Invest New Drugs (2017) 0.75
Recombinant fibromodulin and decorin effects on NF-κB and TGFβ1 in the 4T1 breast cancer cell line. Oncol Lett (2017) 0.75
Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development. J Cell Biochem (2006) 2.71
Language, thought, and color: Whorf was half right. Trends Cogn Sci (2009) 2.57
Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction. J Biol Chem (2008) 2.53
Whorf hypothesis is supported in the right visual field but not the left. Proc Natl Acad Sci U S A (2005) 2.25
The role of decorin in collagen fibrillogenesis and skin homeostasis. Glycoconj J (2003) 2.13
The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells. Blood (2011) 1.89
Modulation of canonical Wnt signaling by the extracellular matrix component biglycan. Proc Natl Acad Sci U S A (2011) 1.85
Extracellular matrix proteoglycans control the fate of bone marrow stromal cells. J Biol Chem (2005) 1.82
Focal colors are universal after all. Proc Natl Acad Sci U S A (2005) 1.81
Color naming reflects optimal partitions of color space. Proc Natl Acad Sci U S A (2007) 1.80
Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan. J Biol Chem (2009) 1.79
Decorin is a novel antagonistic ligand of the Met receptor. J Cell Biol (2009) 1.76
FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney. Development (2013) 1.71
Influence of decorin and biglycan on mechanical properties of multiple tendons in knockout mice. J Biomech Eng (2005) 1.71
Endorepellin, a novel inhibitor of angiogenesis derived from the C terminus of perlecan. J Biol Chem (2002) 1.67
Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin. J Cell Biol (2004) 1.61
Host response to implanted porcine-derived biologic materials in a primate model of abdominal wall repair. Tissue Eng Part A (2008) 1.60
Decorin, a novel player in the insulin-like growth factor system. J Biol Chem (2005) 1.59
Heparan sulfate: a complex polymer charged with biological activity. Chem Rev (2005) 1.57
Decorin suppresses tumor cell-mediated angiogenesis. Oncogene (2002) 1.57
Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation. J Biol Chem (2006) 1.55
Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope. J Biol Chem (2002) 1.53
Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction. Am J Pathol (2002) 1.52
Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis. Cell Cycle (2011) 1.52
Tumor microenvironment: Modulation by decorin and related molecules harboring leucine-rich tandem motifs. Int J Cancer (2008) 1.51
Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21. Sci Signal (2011) 1.50
Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis. J Biol Chem (2005) 1.50
Diverse cell signaling events modulated by perlecan. Biochemistry (2008) 1.49
Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts. Cancer Biol Ther (2011) 1.48
Proepithelin promotes migration and invasion of 5637 bladder cancer cells through the activation of ERK1/2 and the formation of a paxillin/FAK/ERK complex. Cancer Res (2006) 1.46
Decorin: a guardian from the matrix. Am J Pathol (2012) 1.46
Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin. Oncogene (2002) 1.42
Biologically active decorin is a monomer in solution. J Biol Chem (2003) 1.40
Decorin expression is important for age-related changes in tendon structure and mechanical properties. Matrix Biol (2012) 1.39
Effect of altered matrix proteins on quasilinear viscoelastic properties in transgenic mouse tail tendons. Ann Biomed Eng (2003) 1.38
Angiogenesis in collagen I requires alpha2beta1 ligation of a GFP*GER sequence and possibly p38 MAPK activation and focal adhesion disassembly. J Biol Chem (2003) 1.36
Impacts of anthropogenic activity on the ecology of class 1 integrons and integron-associated genes in the environment. ISME J (2011) 1.35
An antimetastatic role for decorin in breast cancer. Am J Pathol (2008) 1.34
A role for decorin in cutaneous wound healing and angiogenesis. Wound Repair Regen (2006) 1.33
Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels. J Biol Chem (2010) 1.32
Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis. J Biol Chem (2003) 1.31
BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan. J Biol Chem (2004) 1.31
The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis. FEBS J (2007) 1.31
Host response to human acellular dermal matrix transplantation in a primate model of abdominal wall repair. Tissue Eng Part A (2008) 1.30
A novel interaction between perlecan protein core and progranulin: potential effects on tumor growth. J Biol Chem (2003) 1.30
Decorin deficiency leads to impaired angiogenesis in injured mouse cornea. J Vasc Res (2004) 1.29
Protective niche for Borrelia burgdorferi to evade humoral immunity. Am J Pathol (2004) 1.29
Matrix revolutions: "tails" of basement-membrane components with angiostatic functions. Trends Cell Biol (2005) 1.28
Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation. Carcinogenesis (2008) 1.28
Decorin causes autophagy in endothelial cells via Peg3. Proc Natl Acad Sci U S A (2013) 1.22
A central function for perlecan in skeletal muscle and cardiovascular development. J Cell Biol (2008) 1.22
Biological interplay between proteoglycans and their innate immune receptors in inflammation. FEBS J (2013) 1.22
Strain-rate sensitive mechanical properties of tendon fascicles from mice with genetically engineered alterations in collagen and decorin. J Biomech Eng (2004) 1.22
Decorin deficiency enhances progressive nephropathy in diabetic mice. Am J Pathol (2007) 1.22
In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer. FASEB J (2003) 1.22
Influence of decorin on the mechanical, compositional, and structural properties of the mouse patellar tendon. J Biomech Eng (2012) 1.20
Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin. Am J Pathol (2007) 1.20
Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3. J Biol Chem (2011) 1.20
Interactions of the extracellular matrix proteoglycans decorin and biglycan with C1q and collectins. J Immunol (2005) 1.19
Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism. J Natl Cancer Inst (2006) 1.17
Color naming and sunlight: commentary on Lindsey and Brown (2002). Psychol Sci (2004) 1.17
Decorin suppresses prostate tumor growth through inhibition of epidermal growth factor and androgen receptor pathways. Neoplasia (2009) 1.16
Color naming, lens aging, and grue: what the optics of the aging eye can teach us about color language. Psychol Sci (2005) 1.14
Effect of age and proteoglycan deficiency on collagen fiber re-alignment and mechanical properties in mouse supraspinatus tendon. J Biomech Eng (2013) 1.13
Investigating tendon fascicle structure-function relationships in a transgenic-age mouse model using multiple regression models. Ann Biomed Eng (2004) 1.13
Support for lateralization of the Whorf effect beyond the realm of color discrimination. Brain Lang (2007) 1.13
The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin. Am J Pathol (2010) 1.13
Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation. Curr Opin Genet Dev (2012) 1.11
Endothelial cells provide feedback control for vascular remodeling through a mechanosensitive autocrine TGF-beta signaling pathway. Circ Res (2008) 1.11
Perlecan proteolysis induces an alpha2beta1 integrin- and Src family kinase-dependent anti-apoptotic pathway in fibroblasts in the absence of focal adhesion kinase activation. J Biol Chem (2006) 1.11
Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation. Cell Cycle (2012) 1.11
Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice. Carcinogenesis (2011) 1.10
Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A. J Biol Chem (2012) 1.09
Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model. PLoS One (2012) 1.09
Peroxisome proliferator-activated receptor gamma-mediated up-regulation of syndecan-1 by n-3 fatty acids promotes apoptosis of human breast cancer cells. Cancer Res (2008) 1.09
Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth. Am J Pathol (2009) 1.08
Decorin-TGFβ axis in hepatic fibrosis and cirrhosis. J Histochem Cytochem (2012) 1.08
A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis. Am J Pathol (2009) 1.07
A role for decorin in the remodeling of myocardial infarction. Matrix Biol (2005) 1.07
A multilayered synthetic human elastin/polycaprolactone hybrid vascular graft with tailored mechanical properties. Acta Biomater (2010) 1.06
Novel interactions of perlecan: unraveling perlecan's role in angiogenesis. Microsc Res Tech (2008) 1.06
Language regions of brain are operative in color perception. Proc Natl Acad Sci U S A (2009) 1.06