|
1
|
Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.
|
J Cell Biol
|
2010
|
2.98
|
|
2
|
The Rab27a/granuphilin complex regulates the exocytosis of insulin-containing dense-core granules.
|
Mol Cell Biol
|
2002
|
1.87
|
|
3
|
Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation.
|
J Clin Invest
|
2005
|
1.75
|
|
4
|
Granuphilin molecularly docks insulin granules to the fusion machinery.
|
J Cell Biol
|
2005
|
1.66
|
|
5
|
Modular genetic control of sexually dimorphic behaviors.
|
Cell
|
2012
|
1.50
|
|
6
|
Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions.
|
FEBS Lett
|
2002
|
1.50
|
|
7
|
Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a.
|
Structure
|
2008
|
1.33
|
|
8
|
Involvement of Rab27b in the regulated secretion of pituitary hormones.
|
Endocrinology
|
2002
|
1.30
|
|
9
|
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis.
|
Biochem Biophys Res Commun
|
2004
|
1.29
|
|
10
|
Docking is not a prerequisite but a temporal constraint for fusion of secretory granules.
|
Traffic
|
2008
|
1.26
|
|
11
|
Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane.
|
Mol Biol Cell
|
2007
|
1.24
|
|
12
|
Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a.
|
Mol Cell Biol
|
2002
|
1.22
|
|
13
|
Rab27b is associated with fusiform vesicles and may be involved in targeting uroplakins to urothelial apical membranes.
|
Proc Natl Acad Sci U S A
|
2003
|
1.20
|
|
14
|
Rab27 effector granuphilin promotes the plasma membrane targeting of insulin granules via interaction with syntaxin 1a.
|
J Biol Chem
|
2004
|
1.18
|
|
15
|
Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice.
|
Cell Metab
|
2006
|
1.07
|
|
16
|
Secretogranin III binds to cholesterol in the secretory granule membrane as an adapter for chromogranin A.
|
J Biol Chem
|
2003
|
1.00
|
|
17
|
Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain.
|
Mol Biol Cell
|
2006
|
0.99
|
|
18
|
Cytoplasmic transport signal is involved in phogrin targeting and localization to secretory granules.
|
Traffic
|
2005
|
0.97
|
|
19
|
Chromosome 2 locus Nidd5 has a potent effect on adiposity in the TSOD mouse.
|
Mamm Genome
|
2006
|
0.93
|
|
20
|
In vivo gene delivery by cationic tetraamino fullerene.
|
Proc Natl Acad Sci U S A
|
2010
|
0.93
|
|
21
|
Involvement of vps33a in the fusion of uroplakin-degrading multivesicular bodies with lysosomes.
|
Traffic
|
2009
|
0.91
|
|
22
|
TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis.
|
Endocrinology
|
2013
|
0.90
|
|
23
|
Parathyroid hormone-related protein induces insulin expression through activation of MAP kinase-specific phosphatase-1 that dephosphorylates c-Jun NH2-terminal kinase in pancreatic beta-cells.
|
Diabetes
|
2003
|
0.88
|
|
24
|
Structure of the small GTPase Rab27b shows an unexpected swapped dimer.
|
Acta Crystallogr D Biol Crystallogr
|
2007
|
0.88
|
|
25
|
A subset of p23 localized on secretory granules in pancreatic beta-cells.
|
J Histochem Cytochem
|
2006
|
0.88
|
|
26
|
Loss of granuphilin and loss of syntaxin-1A cause differential effects on insulin granule docking and fusion.
|
J Biol Chem
|
2011
|
0.87
|
|
27
|
Activin receptor-like kinase 7 suppresses lipolysis to accumulate fat in obesity through downregulation of peroxisome proliferator-activated receptor γ and C/EBPα.
|
Diabetes
|
2012
|
0.87
|
|
28
|
Exophilin8 transiently clusters insulin granules at the actin-rich cell cortex prior to exocytosis.
|
Mol Biol Cell
|
2011
|
0.86
|
|
29
|
The Rab27a effector exophilin7 promotes fusion of secretory granules that have not been docked to the plasma membrane.
|
Mol Biol Cell
|
2012
|
0.84
|
|
30
|
Proprotein-Processing Endoprotease Furin and its Substrate Parathyroid Hormone-Related Protein Are Coexpressed in Insulinoma Cells.
|
Endocr Pathol
|
2000
|
0.80
|
|
31
|
Functional localization of proprotein-convertase furin and its substrate TGFbeta in EGF receptor-expressing gastric chief cells.
|
Growth Factors
|
2004
|
0.80
|
|
32
|
Neuropathological study of C57BL/6Akita mouse, type 2 diabetic model: enhanced expression of alphaB-crystallin in oligodendrocytes.
|
Neuropathology
|
2003
|
0.80
|
|
33
|
Syntaxin 8 has two functionally distinct di-leucine-based motifs.
|
Cell Mol Biol Lett
|
2007
|
0.78
|
|
34
|
Functional analysis of Rab27a effector granuphilin in insulin exocytosis.
|
Methods Enzymol
|
2005
|
0.78
|
|
35
|
Roles of activin receptor-like kinase 7 signaling and its target, peroxisome proliferator-activated receptor γ, in lean and obese adipocytes.
|
Adipocyte
|
2013
|
0.76
|
|
36
|
Purification, crystallization and preliminary X-ray crystallographic analysis of Rab27a GTPase in complex with exophilin4/Slp2-a effector.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2008
|
0.75
|