1
|
Genomic responses in mouse models poorly mimic human inflammatory diseases.
|
Proc Natl Acad Sci U S A
|
2013
|
16.74
|
2
|
A network-based analysis of systemic inflammation in humans.
|
Nature
|
2005
|
12.60
|
3
|
A genomic storm in critically injured humans.
|
J Exp Med
|
2011
|
6.67
|
4
|
Application of genome-wide expression analysis to human health and disease.
|
Proc Natl Acad Sci U S A
|
2005
|
3.49
|
5
|
Whole blood and leukocyte RNA isolation for gene expression analyses.
|
Physiol Genomics
|
2004
|
3.22
|
6
|
The surgical intensive care unit optimal mobility score predicts mortality and length of stay.
|
Crit Care Med
|
2012
|
2.30
|
7
|
Depletion of dendritic cells, but not macrophages, in patients with sepsis.
|
J Immunol
|
2002
|
2.25
|
8
|
Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures.
|
Ann Surg
|
2012
|
2.07
|
9
|
Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways.
|
Proc Natl Acad Sci U S A
|
2006
|
1.82
|
10
|
A genomic score prognostic of outcome in trauma patients.
|
Mol Med
|
2009
|
1.48
|
11
|
Open source clinical science for emerging infections.
|
Lancet Infect Dis
|
2014
|
1.47
|
12
|
Myocardial transcriptional profiles in a murine model of sepsis: evidence for the importance of age.
|
Pediatr Crit Care Med
|
2008
|
1.43
|
13
|
TAT-BH4 and TAT-Bcl-xL peptides protect against sepsis-induced lymphocyte apoptosis in vivo.
|
J Immunol
|
2006
|
1.41
|
14
|
Challenges and a new vision for academic surgery.
|
J Am Coll Surg
|
2005
|
1.40
|
15
|
Commonality and differences in leukocyte gene expression patterns among three models of inflammation and injury.
|
Physiol Genomics
|
2005
|
1.40
|
16
|
Analysis of factorial time-course microarrays with application to a clinical study of burn injury.
|
Proc Natl Acad Sci U S A
|
2010
|
1.33
|
17
|
Comparison of longitudinal leukocyte gene expression after burn injury or trauma-hemorrhage in mice.
|
Physiol Genomics
|
2007
|
1.30
|
18
|
DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitis.
|
J Exp Med
|
2005
|
1.22
|
19
|
Plasticity of the systemic inflammatory response to acute infection during critical illness: development of the riboleukogram.
|
PLoS One
|
2008
|
1.19
|
20
|
Streptococcus pneumoniae and Pseudomonas aeruginosa pneumonia induce distinct host responses.
|
Crit Care Med
|
2010
|
1.14
|
21
|
Temporal changes in mouse aortic wall gene expression during the development of elastase-induced abdominal aortic aneurysms.
|
J Vasc Surg
|
2006
|
1.10
|
22
|
Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation.
|
Blood
|
2005
|
1.10
|
23
|
Global gene expression in neuroendocrine tumors from patients with the MEN1 syndrome.
|
Mol Cancer
|
2005
|
1.05
|
24
|
Molecular diagnostics in sepsis: from bedside to bench.
|
J Am Coll Surg
|
2006
|
1.02
|
25
|
Splenic CD4+ T cells have a distinct transcriptional response six hours after the onset of sepsis.
|
J Am Coll Surg
|
2006
|
0.99
|
26
|
Surviving sepsis: bcl-2 overexpression modulates splenocyte transcriptional responses in vivo.
|
Am J Physiol Regul Integr Comp Physiol
|
2007
|
0.92
|
27
|
Differences in outcome between obese and nonobese patients following severe blunt trauma are not consistent with an early inflammatory genomic response.
|
Crit Care Med
|
2010
|
0.91
|
28
|
Transcriptional profiles of human epithelial cells in response to heat: computational evidence for novel heat shock proteins.
|
Shock
|
2008
|
0.90
|
29
|
That which does not kill you makes you stronger: a molecular mechanism for preconditioning.
|
Sci STKE
|
2005
|
0.88
|
30
|
Using systems biology to simplify complex disease: immune cartography.
|
Crit Care Med
|
2009
|
0.86
|
31
|
Gene expression profiles of livers from thermally injured rats.
|
Gene
|
2004
|
0.86
|
32
|
Early observational research and registries during the 2009-2010 influenza A pandemic.
|
Crit Care Med
|
2010
|
0.85
|
33
|
Functional genomics of critical illness and injury.
|
Crit Care Med
|
2002
|
0.84
|
34
|
Global participation in core data sets for emerging pathogens.
|
Am J Respir Crit Care Med
|
2015
|
0.83
|
35
|
Surrogate consent for genomics research in intensive care.
|
Am J Crit Care
|
2009
|
0.81
|
36
|
The murine plasma protein response to polymicrobial intra-abdominal sepsis.
|
Proteomics Clin Appl
|
2007
|
0.80
|
37
|
Physiologic genomics.
|
Surgery
|
2006
|
0.80
|
38
|
Assessment of satisfaction with care among family members of survivors in a neuroscience intensive care unit.
|
J Neurosci Nurs
|
2014
|
0.78
|
39
|
Evidence for a novel blood RNA diagnostic for pediatric appendicitis: the riboleukogram.
|
Pediatr Emerg Care
|
2010
|
0.78
|
40
|
Candida infection and colonization in critically ill surgical patients.
|
Virulence
|
2010
|
0.77
|
41
|
Safety evaluation of a Medical Device Data System.
|
Conf Proc IEEE Eng Med Biol Soc
|
2012
|
0.77
|
42
|
Sequence makes a difference: paradoxical effects of stress in vivo.
|
Shock
|
2004
|
0.77
|
43
|
Estimating sparse gene regulatory networks using a bayesian linear regression.
|
IEEE Trans Nanobioscience
|
2010
|
0.76
|
44
|
Preliminary evidence for leukocyte transcriptional signatures for pediatric ventilator-associated pneumonia.
|
J Intensive Care Med
|
2011
|
0.76
|
45
|
Novel diagnostics for sepsis: a decade of promise for gene expression profiling.
|
Crit Care Med
|
2011
|
0.76
|
46
|
Clustering analysis to identify distinct spectral components of encephalogram burst suppression in critically ill patients.
|
Conf Proc IEEE Eng Med Biol Soc
|
2015
|
0.75
|
47
|
Putting the patient first: honoring advance directives prior to surgery.
|
Ann Surg
|
2012
|
0.75
|
48
|
Ten years later, still "gene in a haystack?".
|
Crit Care Med
|
2011
|
0.75
|
49
|
United States Critical Illness and Injury Trials Group.
|
Chest
|
2013
|
0.75
|
50
|
Development of a Core Clinical Dataset to Characterize Serious Illness, Injuries, and Resource Requirements for Acute Medical Responses to Public Health Emergencies.
|
Crit Care Med
|
2015
|
0.75
|
51
|
Implementation of 24/7 intensivist presence in the SICU: effect on processes of care.
|
J Trauma Acute Care Surg
|
2013
|
0.75
|