Published in Endocrinology on February 03, 2005
PTH and PTHrP signaling in osteoblasts. Cell Signal (2009) 1.69
In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation. J Biol Chem (2008) 1.06
Two PEST-like motifs regulate Ca2+/calpain-mediated cleavage of the CaVbeta3 subunit and provide important determinants for neuronal Ca2+ channel activity. Eur J Neurosci (2006) 0.94
Role of PTH1R internalization in osteoblasts and bone mass using a phosphorylation-deficient knock-in mouse model. J Endocrinol (2010) 0.93
Targeted deletion of Capn4 in cells of the chondrocyte lineage impairs chondrocyte proliferation and differentiation. Mol Cell Biol (2010) 0.91
The calpain small subunit regulates cell-substrate mechanical interactions during fibroblast migration. J Cell Sci (2008) 0.85
Identification of QTL genes for BMD variation using both linkage and gene-based association approaches. Hum Genet (2011) 0.80
Calpain modulates cyclin-dependent kinase inhibitor 1B (p27(Kip1)) in cells of the osteoblast lineage. Calcif Tissue Int (2011) 0.78
Overview of calpain-mediated regulation of bone and fat mass in osteoblasts. Cell Biochem Biophys (2013) 0.75
Elevated Expression of Calpain-4 Predicts Poor Prognosis in Patients with Gastric Cancer after Gastrectomy. Int J Mol Sci (2016) 0.75
Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis. Mol Cell Biol (2007) 2.22
Na(+)/H(+ ) exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling. Nature (2002) 1.94
Apicomplexan parasites co-opt host calpains to facilitate their escape from infected cells. Science (2009) 1.77
Ubiquitous calpains promote caspase-12 and JNK activation during endoplasmic reticulum stress-induced apoptosis. J Biol Chem (2006) 1.54
17beta-estradiol and tamoxifen stimulate rapid and transient ERK activationin MCF-7 cells via distinct signaling mechanisms. Cancer Biol Ther (2006) 1.49
m-Calpain is required for preimplantation embryonic development in mice. BMC Dev Biol (2006) 1.37
Mechanisms of ligand binding to the parathyroid hormone (PTH)/PTH-related protein receptor: selectivity of a modified PTH(1-15) radioligand for GalphaS-coupled receptor conformations. Mol Endocrinol (2005) 1.36
Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase. Biochem J (2004) 1.31
Stimulation by parathyroid hormone of a NHERF-1-assembled complex consisting of the parathyroid hormone I receptor, phospholipase Cbeta, and actin increases intracellular calcium in opossum kidney cells. J Biol Chem (2004) 1.29
Ubiquitous calpains promote both apoptosis and survival signals in response to different cell death stimuli. J Biol Chem (2006) 1.25
Fer-mediated cortactin phosphorylation is associated with efficient fibroblast migration and is dependent on reactive oxygen species generation during integrin-mediated cell adhesion. Mol Cell Biol (2007) 1.22
Control of vesicle fusion by a tyrosine phosphatase. Nat Cell Biol (2004) 1.21
Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos). J Neurochem (2009) 1.16
Targeted inhibition of calpain reduces myocardial hypertrophy and fibrosis in mouse models of type 1 diabetes. Diabetes (2011) 1.15
Conditional disruption of ubiquitous calpains in the mouse. Genesis (2006) 1.13
Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease. J Clin Invest (2011) 1.11
In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation. J Biol Chem (2008) 1.06
Calcium-dependent plasma membrane repair requires m- or mu-calpain, but not calpain-3, the proteasome, or caspases. Biochim Biophys Acta (2009) 1.06
Fer kinase is required for sustained p38 kinase activation and maximal chemotaxis of activated mast cells. Mol Cell Biol (2002) 1.06
Phosphorylation of N-cadherin-associated cortactin by Fer kinase regulates N-cadherin mobility and intercellular adhesion strength. Mol Biol Cell (2005) 1.04
Calpains mediate p53 activation and neuronal death evoked by DNA damage. J Biol Chem (2003) 1.02
Continuous activation of G alpha q in osteoblasts results in osteopenia through impaired osteoblast differentiation. J Biol Chem (2007) 1.01
Na+/H+ exchanger-regulatory factor 1 mediates inhibition of phosphate transport by parathyroid hormone and second messengers by acting at multiple sites in opossum kidney cells. Mol Endocrinol (2003) 1.01
Coding GNAS mutations leading to hormone resistance impair in vitro agonist- and cholera toxin-induced adenosine cyclic 3',5'-monophosphate formation mediated by human XLalphas. Endocrinology (2006) 1.00
Absence of Fer protein-tyrosine kinase exacerbates leukocyte recruitment in response to endotoxin. J Immunol (2002) 1.00
Conditional disruption of calpain in the CNS alters dendrite morphology, impairs LTP, and promotes neuronal survival following injury. J Neurosci (2013) 0.97
Calpain 2 regulates Akt-FoxO-p27(Kip1) protein signaling pathway in mammary carcinoma. J Biol Chem (2012) 0.97
Acute down-regulation of sodium-dependent phosphate transporter NPT2a involves predominantly the cAMP/PKA pathway as revealed by signaling-selective parathyroid hormone analogs. J Biol Chem (2010) 0.95
Deficiency of Capn4 gene inhibits nuclear factor-κB (NF-κB) protein signaling/inflammation and reduces remodeling after myocardial infarction. J Biol Chem (2012) 0.94
Fps/Fes and Fer protein-tyrosinekinases play redundant roles in regulating hematopoiesis. Exp Hematol (2003) 0.93
Purification and characterization of a receptor for human parathyroid hormone and parathyroid hormone-related peptide. J Biol Chem (2002) 0.93
The Fps/Fes kinase regulates the inflammatory response to endotoxin through down-regulation of TLR4, NF-kappaB activation, and TNF-alpha secretion in macrophages. J Leukoc Biol (2006) 0.92
Targeted deletion of Capn4 in cells of the chondrocyte lineage impairs chondrocyte proliferation and differentiation. Mol Cell Biol (2010) 0.91
Calpain is required for MMP-2 and u-PA expression in SV40 large T-antigen-immortalized cells. Biochem Biophys Res Commun (2002) 0.88
Fer kinase limits neutrophil chemotaxis toward end target chemoattractants. J Immunol (2013) 0.88
The Fer tyrosine kinase regulates an axon retraction response to Semaphorin 3A in dorsal root ganglion neurons. BMC Dev Biol (2007) 0.86
Enhanced endotoxin sensitivity in fps/fes-null mice with minimal defects in hematopoietic homeostasis. Mol Cell Biol (2002) 0.86
Feline sarcoma-related protein expression correlates with malignant aggressiveness and poor prognosis in renal cell carcinoma. Cancer Sci (2013) 0.85
The calpain small subunit regulates cell-substrate mechanical interactions during fibroblast migration. J Cell Sci (2008) 0.85
An identity crisis for fps/fes: oncogene or tumor suppressor? Cancer Res (2005) 0.84
Flavopiridol synergizes with sorafenib to induce cytotoxicity and potentiate antitumorigenic activity in EGFR/HER-2 and mutant RAS/RAF breast cancer model systems. Neoplasia (2013) 0.83
The Fps/Fes kinase regulates leucocyte recruitment and extravasation during inflammation. Immunology (2007) 0.83
Activated Fps/Fes tyrosine kinase regulates erythroid differentiation and survival. Exp Hematol (2004) 0.82
Fes tyrosine kinase expression in the tumor niche correlates with enhanced tumor growth, angiogenesis, circulating tumor cells, metastasis, and infiltrating macrophages. Cancer Res (2010) 0.82
Calpain-mediated degradation of reversibly oxidized protein-tyrosine phosphatase 1B. FEBS J (2009) 0.81
G alpha(q) signal in osteoblasts is inhibitory to the osteoanabolic action of parathyroid hormone. J Biol Chem (2011) 0.81
FES kinase promotes mast cell recruitment to mammary tumors via the stem cell factor/KIT receptor signaling axis. Mol Cancer Res (2012) 0.80
Calpain 4 is not necessary for LFA-1-mediated function in CD4+ T cells. PLoS One (2010) 0.80
fps/fes knockout mice display a lactation defect and the fps/fes tyrosine kinase is a component of E-cadherin-based adherens junctions in breast epithelial cells during lactation. Exp Cell Res (2009) 0.79
Genetic disruption of calpain correlates with loss of membrane blebbing and differential expression of RhoGDI-1, cofilin and tropomyosin. Biochem J (2008) 0.78
Calpains promote neutrophil recruitment and bacterial clearance in an acute bacterial peritonitis model. Eur J Immunol (2013) 0.77
Pathological significance and predictive value for biochemical recurrence of c-Fes expression in prostate cancer. Prostate (2011) 0.77
Fluorescent ligand-directed co-localization of the parathyroid hormone 1 receptor with the brush-border scaffold complex of the proximal tubule reveals hormone-dependent changes in ezrin immunoreactivity consistent with inactivation. Biochim Biophys Acta (2012) 0.77
The fps/fes proto-oncogene regulates hematopoietic lineage output. Exp Hematol (2003) 0.77