Published in Science on February 04, 2005
Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus. J Virol (2005) 4.01
Kaposi's sarcoma and its associated herpesvirus. Nat Rev Cancer (2010) 3.55
Identification of cellular genes targeted by KSHV-encoded microRNAs. PLoS Pathog (2007) 3.16
KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine. J Clin Invest (2010) 2.55
The ubiquitin E3 ligase RAUL negatively regulates type i interferon through ubiquitination of the transcription factors IRF7 and IRF3. Immunity (2010) 2.13
The epigenetic landscape of latent Kaposi sarcoma-associated herpesvirus genomes. PLoS Pathog (2010) 1.97
Virus and cell RNAs expressed during Epstein-Barr virus replication. J Virol (2006) 1.80
Host and viral proteins in the virion of Kaposi's sarcoma-associated herpesvirus. J Virol (2005) 1.74
Viral latency and its regulation: lessons from the gamma-herpesviruses. Cell Host Microbe (2010) 1.70
mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine. Pharmacol Ther (2006) 1.56
Kaposi sarcoma-associated herpesvirus (KSHV): molecular biology and oncogenesis. Cancer Lett (2009) 1.54
Viruses associated with human cancer. Biochim Biophys Acta (2007) 1.47
Molecular biology of KSHV in relation to AIDS-associated oncogenesis. Cancer Treat Res (2007) 1.47
Human viral oncogenesis: a cancer hallmarks analysis. Cell Host Microbe (2014) 1.42
Array-based transcript profiling and limiting-dilution reverse transcription-PCR analysis identify additional latent genes in Kaposi's sarcoma-associated herpesvirus. J Virol (2010) 1.42
Gammaherpesvirus and lymphoproliferative disorders in immunocompromised patients. Cancer Lett (2011) 1.41
Reactivation of Kaposi's sarcoma-associated herpesvirus from latency requires MEK/ERK, JNK and p38 multiple mitogen-activated protein kinase pathways. Virology (2007) 1.38
The functions of herpesvirus-encoded microRNAs. Med Microbiol Immunol (2007) 1.35
Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion. PLoS Pathog (2010) 1.35
Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases. J Virol (2007) 1.34
Kaposi's sarcoma-associated herpesvirus promotes angiogenesis by inducing angiopoietin-2 expression via AP-1 and Ets1. J Virol (2007) 1.32
Systematic identification of cellular signals reactivating Kaposi sarcoma-associated herpesvirus. PLoS Pathog (2007) 1.32
ORF18 is a transfactor that is essential for late gene transcription of a gammaherpesvirus. J Virol (2006) 1.24
Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner. Proc Natl Acad Sci U S A (2007) 1.20
Herpes simplex virus ICP27 activation of stress kinases JNK and p38. J Virol (2005) 1.15
Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus. J Virol (2006) 1.13
RNA editing of the human herpesvirus 8 kaposin transcript eliminates its transforming activity and is induced during lytic replication. J Virol (2007) 1.11
Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesis. Adv Virus Res (2010) 1.09
NF-kappaB serves as a cellular sensor of Kaposi's sarcoma-associated herpesvirus latency and negatively regulates K-Rta by antagonizing the RBP-Jkappa coactivator. J Virol (2009) 1.04
A repetitive region of gammaherpesvirus genomic DNA is a ligand for induction of type I interferon. J Virol (2007) 1.02
Host transcript accumulation during lytic KSHV infection reveals several classes of host responses. PLoS One (2007) 1.00
KSHV: pathways to tumorigenesis and persistent infection. Adv Virus Res (2014) 0.99
Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine expression. J Immunol (2009) 0.99
Expanding the role of Drosha to the regulation of viral gene expression. Proc Natl Acad Sci U S A (2011) 0.99
Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma. PLoS One (2011) 0.98
Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 gene. J Virol (2006) 0.97
Multicentric Castleman disease: Where are we now? Semin Diagn Pathol (2016) 0.94
Current status of treatment for primary effusion lymphoma. Intractable Rare Dis Res (2014) 0.93
Deep sequencing reveals direct targets of gammaherpesvirus-induced mRNA decay and suggests that multiple mechanisms govern cellular transcript escape. PLoS One (2011) 0.93
Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus. PLoS Pathog (2010) 0.91
KSHV LANA--the master regulator of KSHV latency. Viruses (2014) 0.91
The modulation of apoptosis by oncogenic viruses. Virol J (2013) 0.89
KSHV/HHV-8 and HIV infection in Kaposi's sarcoma development. Infect Agent Cancer (2007) 0.89
Kaposi's sarcoma-associated herpesvirus and innate immunity. Future Virol (2010) 0.85
Phosphorylation and function of the kaposin B direct repeats of Kaposi's sarcoma-associated herpesvirus. J Virol (2006) 0.84
Control of Rta expression critically determines transcription of viral and cellular genes following gammaherpesvirus infection. J Gen Virol (2007) 0.84
Molecular biology of human herpesvirus 8: novel functions and virus-host interactions implicated in viral pathogenesis and replication. Recent Results Cancer Res (2014) 0.84
An RNA element in human interleukin 6 confers escape from degradation by the gammaherpesvirus SOX protein. J Virol (2013) 0.83
Stimulation of mesenchymal stromal cells (MSCs) via TLR3 reveals a novel mechanism of autocrine priming. FASEB J (2014) 0.82
The M10 locus of murine gammaherpesvirus 68 contributes to both the lytic and the latent phases of infection. J Virol (2009) 0.82
A ribonucleoprotein complex protects the interleukin-6 mRNA from degradation by distinct herpesviral endonucleases. PLoS Pathog (2015) 0.81
Activation of DNA Damage Response Induced by the Kaposi's Sarcoma-Associated Herpes Virus. Int J Mol Sci (2016) 0.80
Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population. J Gen Virol (2012) 0.80
A gammaherpesviral internal repeat contributes to latency amplification. PLoS One (2007) 0.80
Interplay between Kaposi's sarcoma-associated herpesvirus and the innate immune system. Cytokine Growth Factor Rev (2014) 0.80
Inefficient Codon Usage Impairs mRNA Accumulation: the Case of the v-FLIP Gene of Kaposi's Sarcoma-Associated Herpesvirus. J Virol (2015) 0.80
Kaposi's sarcoma-associated herpesvirus G-protein-coupled receptor prevents AU-rich-element-mediated mRNA decay. J Virol (2012) 0.80
Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate reprogramming by Kaposi sarcoma herpes virus. PLoS Pathog (2012) 0.80
Virus-associated lymphomagenesis. Int J Biomed Sci (2006) 0.79
Kaposi Sarcoma Pathogenesis: A Triad of Viral Infection, Oncogenesis and Chronic Inflammation. Transl Biomed (2010) 0.79
KSHV Genome Replication and Maintenance. Front Microbiol (2016) 0.78
Chromatinization of the KSHV Genome During the KSHV Life Cycle. Cancers (Basel) (2015) 0.77
Constitutive Activation of Interleukin-13/STAT6 Contributes to Kaposi's Sarcoma-Associated Herpesvirus-Related Primary Effusion Lymphoma Cell Proliferation and Survival. J Virol (2015) 0.77
Anthrax lethal toxin-induced lung injury and treatment by activating MK2. J Appl Physiol (1985) (2015) 0.76
Viral activation of MK2-hsp27-p115RhoGEF-RhoA signaling axis causes cytoskeletal rearrangements, p-body disruption and ARE-mRNA stabilization. PLoS Pathog (2015) 0.76
p38MAPK and MK2 pathways are important for the differentiation-dependent human papillomavirus life cycle. J Virol (2014) 0.76
Kaposi sarcoma herpesvirus pathogenesis. Philos Trans R Soc Lond B Biol Sci (2017) 0.76
c-Myc and viral cofactor Kaposin B co-operate to elicit angiogenesis through modulating miRNome traits of endothelial cells. BMC Syst Biol (2016) 0.75
Characterization of c-Kit expression and activation in KSHV-infected endothelial cells. Virology (2009) 0.75
Viral activation of stress-regulated Rho-GTPase signaling pathway disrupts sites of mRNA degradation to influence cellular gene expression. Small GTPases (2015) 0.75
KSHV-Mediated Angiogenesis in Tumor Progression. Viruses (2016) 0.75
Abnormalities in alternative splicing of angiogenesis-related genes and their role in HIV-related cancers. HIV AIDS (Auckl) (2017) 0.75
KSHV and the Role of Notch Receptor Dysregulation in Disease Progression. Pathogens (2017) 0.75
microRNA dependent and independent deregulation of long non-coding RNAs by an oncogenic herpesvirus. PLoS Pathog (2017) 0.75
Nuclease escape elements protect messenger RNA against cleavage by multiple viral endonucleases. PLoS Pathog (2017) 0.75
Retracted Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant. PLoS Pathog (2006) 10.08
Microarray-based detection and genotyping of viral pathogens. Proc Natl Acad Sci U S A (2002) 7.27
Viral discovery and sequence recovery using DNA microarrays. PLoS Biol (2003) 5.95
SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells. Nature (2005) 5.54
An infectious retrovirus susceptible to an IFN antiviral pathway from human prostate tumors. Proc Natl Acad Sci U S A (2007) 4.77
A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses. RNA (2006) 4.47
Pan-viral screening of respiratory tract infections in adults with and without asthma reveals unexpected human coronavirus and human rhinovirus diversity. J Infect Dis (2007) 4.16
Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis. J Clin Invest (2004) 3.39
Identification of cardioviruses related to Theiler's murine encephalomyelitis virus in human infections. Proc Natl Acad Sci U S A (2008) 2.84
MicroRNAs and viral infection. Mol Cell (2005) 2.81
Recovery of divergent avian bornaviruses from cases of proventricular dilatation disease: identification of a candidate etiologic agent. Virol J (2008) 2.69
Host range of Kaposi's sarcoma-associated herpesvirus in cultured cells. J Virol (2003) 2.60
The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway. Genes Dev (2002) 2.59
De novo infection and serial transmission of Kaposi's sarcoma-associated herpesvirus in cultured endothelial cells. J Virol (2002) 2.55
PHD domains and E3 ubiquitin ligases: viruses make the connection. Trends Cell Biol (2003) 2.45
Tandem array-based expression screens identify host mRNA targets of virus-encoded microRNAs. Nat Genet (2008) 2.42
Lytic KSHV infection inhibits host gene expression by accelerating global mRNA turnover. Mol Cell (2004) 2.31
Human enterovirus 109: a novel interspecies recombinant enterovirus isolated from a case of acute pediatric respiratory illness in Nicaragua. J Virol (2010) 2.31
Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: maintenance of tight latency with efficient reactivation upon induction. J Virol Methods (2011) 2.25
Activation of a nonclassical NKT cell subset in a transgenic mouse model of hepatitis B virus infection. Immunity (2002) 2.17
Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA: an evolutionary adaptation that fine-tunes lytic reactivation. Cell Host Microbe (2009) 2.15
Viral infection in acute exacerbation of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2011) 2.00
Transcriptome sequencing demonstrates that human papillomavirus is not active in cutaneous squamous cell carcinoma. J Invest Dermatol (2011) 1.99
A virus-encoded inhibitor that blocks RNA interference in mammalian cells. J Virol (2005) 1.99
Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone. J Virol (2012) 1.89
The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus permits replication of terminal repeat-containing plasmids. J Virol (2003) 1.87
Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. Clin Infect Dis (2006) 1.84
Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion. Proc Natl Acad Sci U S A (2007) 1.82
Host and viral proteins in the virion of Kaposi's sarcoma-associated herpesvirus. J Virol (2005) 1.74
Viral latency and its regulation: lessons from the gamma-herpesviruses. Cell Host Microbe (2010) 1.70
A unique herpesviral transcriptional program in KSHV-infected lymphatic endothelial cells leads to mTORC1 activation and rapamycin sensitivity. Cell Host Microbe (2013) 1.69
Diagnosis of a critical respiratory illness caused by human metapneumovirus by use of a pan-virus microarray. J Clin Microbiol (2007) 1.67
Regulation of CD1d expression and function by a herpesvirus infection. J Clin Invest (2005) 1.64
Lytic but not latent infection by Kaposi's sarcoma-associated herpesvirus requires host CSL protein, the mediator of Notch signaling. Proc Natl Acad Sci U S A (2003) 1.54
Array-based transcript profiling and limiting-dilution reverse transcription-PCR analysis identify additional latent genes in Kaposi's sarcoma-associated herpesvirus. J Virol (2010) 1.42
Murine Polyomavirus encodes a microRNA that cleaves early RNA transcripts but is not essential for experimental infection. Virology (2009) 1.42
The exonuclease and host shutoff functions of the SOX protein of Kaposi's sarcoma-associated herpesvirus are genetically separable. J Virol (2005) 1.41
Highly selective escape from KSHV-mediated host mRNA shutoff and its implications for viral pathogenesis. J Exp Med (2004) 1.36
Functional organization of MIR2, a novel viral regulator of selective endocytosis. J Biol Chem (2001) 1.34
In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer. PLoS One (2012) 1.33
RBP-J (CSL) is essential for activation of the K14/vGPCR promoter of Kaposi's sarcoma-associated herpesvirus by the lytic switch protein RTA. J Virol (2004) 1.32
Utility of DNA microarrays for detection of viruses in acute respiratory tract infections in children. J Pediatr (2008) 1.26
RNAs in the virion of Kaposi's sarcoma-associated herpesvirus. J Virol (2005) 1.24
Effects of NFkappaB activation on KSHV latency and lytic reactivation are complex and context-dependent. Virology (2008) 1.21
Experimental induction of proventricular dilatation disease in cockatiels (Nymphicus hollandicus) inoculated with brain homogenates containing avian bornavirus 4. Virol J (2009) 1.19
The lytic transcriptome of Kaposi's sarcoma-associated herpesvirus reveals extensive transcription of noncoding regions, including regions antisense to important genes. J Virol (2010) 1.11
Infection of primary human tonsillar lymphoid cells by KSHV reveals frequent but abortive infection of T cells. Virology (2011) 1.06
Viral microRNA target allows insight into the role of translation in governing microRNA target accessibility. Proc Natl Acad Sci U S A (2011) 1.05
Modulation of host gene expression by the constitutively active G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus. Cancer Res (2002) 1.04
Active lytic infection of human primary tonsillar B cells by KSHV and its noncytolytic control by activated CD4+ T cells. J Clin Invest (2011) 1.02
Kaposi's sarcoma-derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line. Int J Cancer (2012) 1.01
Host transcript accumulation during lytic KSHV infection reveals several classes of host responses. PLoS One (2007) 1.00
Induction of chemokine production by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells. J Gen Virol (2007) 0.96
Exploring the DNA binding interactions of the Kaposi's sarcoma-associated herpesvirus lytic switch protein by selective amplification of bound sequences in vitro. J Virol (2006) 0.96
Infection of lymphoblastoid cell lines by Kaposi's sarcoma-associated herpesvirus: critical role of cell-associated virus. J Virol (2011) 0.95
Analysis of naturally occurring avian bornavirus infection and transmission during an outbreak of proventricular dilatation disease among captive psittacine birds. J Virol (2009) 0.93
Kaposi's sarcoma-associated herpesvirus ORF54/dUTPase downregulates a ligand for the NK activating receptor NKp44. J Virol (2012) 0.87
Multiple defects, including premature apoptosis, prevent Kaposi's sarcoma-associated herpesvirus replication in murine cells. J Virol (2011) 0.85
Phosphorylation and function of the kaposin B direct repeats of Kaposi's sarcoma-associated herpesvirus. J Virol (2006) 0.84
A conversation with Don Ganem. J Clin Invest (2014) 0.75