PubRank

Thomas Sommer

Author PubWeight™ 58.34‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 ERAD: the long road to destruction. Nat Cell Biol 2005 7.46
2 Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. Nat Cell Biol 2002 5.02
3 Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nat Cell Biol 2002 4.06
4 Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms. Mol Cell 2010 3.23
5 The ubiquitylation machinery of the endoplasmic reticulum. Nature 2009 2.66
6 A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery. Nat Cell Biol 2006 2.41
7 Ubx2 links the Cdc48 complex to ER-associated protein degradation. Nat Cell Biol 2005 2.12
8 Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum. J Cell Biol 2009 1.93
9 The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment. EMBO J 2006 1.83
10 The ubiquitin-proteasome system of Saccharomyces cerevisiae. Genetics 2012 1.73
11 Usa1 functions as a scaffold of the HRD-ubiquitin ligase. Mol Cell 2009 1.58
12 New modules for the repeated internal and N-terminal epitope tagging of genes in Saccharomyces cerevisiae. Yeast 2005 1.57
13 Protein dislocation from the ER. Biochim Biophys Acta 2010 1.43
14 A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast. J Biol Chem 2002 1.31
15 The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation. Mol Cell 2012 1.30
16 In vivo analysis of importin alpha proteins reveals cellular proliferation inhibition and substrate specificity. Mol Cell Biol 2004 1.29
17 Nuclear localization signal and protein context both mediate importin alpha specificity of nuclear import substrates. Mol Cell Biol 2006 1.29
18 Protein quality control and elimination of protein waste: the role of the ubiquitin-proteasome system. Biochim Biophys Acta 2013 1.28
19 A role for mammalian Ubc6 homologues in ER-associated protein degradation. J Cell Sci 2002 1.26
20 Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation. Mol Cell 2004 1.23
21 Finding the will and the way of ERAD substrate retrotranslocation. Curr Opin Cell Biol 2012 1.16
22 Endoplasmic reticulum-associated protein degradation. Int Rev Cytol 2003 1.16
23 Protein dislocation from the endoplasmic reticulum--pulling out the suspect. Traffic 2002 1.12
24 Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization. EMBO J 2005 1.11
25 Endoplasmic reticulum-associated protein degradation--one model fits all? Biochim Biophys Acta 2004 1.10
26 ERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum. Bioessays 2010 1.08
27 Coping with stress: cellular relaxation techniques. Trends Cell Biol 2006 0.97
28 Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases. Mol Cell 2013 0.88
29 Protein quality control: on IPODs and other JUNQ. Curr Biol 2008 0.86
30 Nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast. Mol Cell Biol 2008 0.85
31 The lysine48-based polyubiquitin chain proteasomal signal: not a single child anymore. Angew Chem Int Ed Engl 2012 0.85
32 Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex. J Biol Chem 2012 0.82
33 Death gives birth to life: the essential role of the ubiquitin-proteasome system in biology. Biochim Biophys Acta 2004 0.76
34 Varshavsky's contributions. Science 2004 0.75