Published in EMBO J on February 03, 2005
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The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment. EMBO J (2006) 1.83
The ubiquitin-proteasome system of Saccharomyces cerevisiae. Genetics (2012) 1.73
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11. Biochemistry (2006) 1.63
Usa1 functions as a scaffold of the HRD-ubiquitin ligase. Mol Cell (2009) 1.58
Comparative proteome analysis of culture supernatant proteins from virulent Mycobacterium tuberculosis H37Rv and attenuated M. bovis BCG Copenhagen. Electrophoresis (2003) 1.57
New modules for the repeated internal and N-terminal epitope tagging of genes in Saccharomyces cerevisiae. Yeast (2005) 1.57
Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations. Circ Cardiovasc Genet (2012) 1.48
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The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition. Nucleic Acids Res (2003) 1.45
Protein dislocation from the ER. Biochim Biophys Acta (2010) 1.43
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Phosphorylation by protein kinase CK2: a signaling switch for the caspase-inhibiting protein ARC. Mol Cell (2002) 1.36
Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation. Structure (2009) 1.36
The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation. Cell Mol Life Sci (2011) 1.35
Kinase inhibitor selectivity profiling using differential scanning fluorimetry. Methods Mol Biol (2012) 1.35
CFP10 discriminates between nonacetylated and acetylated ESAT-6 of Mycobacterium tuberculosis by differential interaction. Proteomics (2004) 1.32
A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast. J Biol Chem (2002) 1.31
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides. Nat Commun (2011) 1.30
The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation. Mol Cell (2012) 1.30
In vivo analysis of importin alpha proteins reveals cellular proliferation inhibition and substrate specificity. Mol Cell Biol (2004) 1.29
Nuclear localization signal and protein context both mediate importin alpha specificity of nuclear import substrates. Mol Cell Biol (2006) 1.29
Protein quality control and elimination of protein waste: the role of the ubiquitin-proteasome system. Biochim Biophys Acta (2013) 1.28
Tetrameric oligomerization of IkappaB kinase gamma (IKKgamma) is obligatory for IKK complex activity and NF-kappaB activation. Mol Cell Biol (2003) 1.26
A role for mammalian Ubc6 homologues in ER-associated protein degradation. J Cell Sci (2002) 1.26
DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer. Cell (2011) 1.25
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Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation. Mol Cell (2004) 1.23
Sequence-specific DNA binding determined by contacts outside the helix-turn-helix motif of the ParB homolog KorB. Nat Struct Mol Biol (2004) 1.21
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Finding the will and the way of ERAD substrate retrotranslocation. Curr Opin Cell Biol (2012) 1.16
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Crystal structure of Escherichia coli phage HK620 tailspike: podoviral tailspike endoglycosidase modules are evolutionarily related. Mol Microbiol (2008) 1.16
Structural genomics of human proteins--target selection and generation of a public catalogue of expression clones. Microb Cell Fact (2005) 1.15
Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate. Proc Natl Acad Sci U S A (2011) 1.15
Serum uric acid as an independent predictor of mortality in patients with angiographically proven coronary artery disease. Am J Cardiol (2002) 1.15
The structure of the dizinc subclass B2 metallo-beta-lactamase CphA reveals that the second inhibitory zinc ion binds in the histidine site. Antimicrob Agents Chemother (2009) 1.14
Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays. Mol Cell Proteomics (2005) 1.13
Protein dislocation from the endoplasmic reticulum--pulling out the suspect. Traffic (2002) 1.12
Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool. Protein Eng Des Sel (2013) 1.11
Characterization of OPA1 isoforms isolated from mouse tissues. J Neurochem (2008) 1.11
The Lin28 cold-shock domain remodels pre-let-7 microRNA. Nucleic Acids Res (2012) 1.10
Endoplasmic reticulum-associated protein degradation--one model fits all? Biochim Biophys Acta (2004) 1.10
Comparison of proteomic and genomic analyses of the human breast cancer cell line T47D and the antiestrogen-resistant derivative T47D-r. Mol Cell Proteomics (2003) 1.10
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The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex. EMBO Rep (2005) 1.08
ERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum. Bioessays (2010) 1.08
The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins. J Struct Funct Genomics (2007) 1.07
Metabolic engineering of Saccharomyces cerevisiae for the biotechnological production of succinic acid. Metab Eng (2010) 1.07
Five birds, one stone: neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody. MAbs (2015) 1.06
High-throughput screening for expression of heterologous proteins in the yeast Pichia pastoris. J Biotechnol (2002) 1.06
Structure of the Bet3-Tpc6B core of TRAPP: two Tpc6 paralogs form trimeric complexes with Bet3 and Mum2. J Mol Biol (2006) 1.06
Crystal structure of Homo sapiens protein hp14.5. Proteins (2004) 1.05
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Toxoplasma gondii inhibits MHC class II expression in neural antigen-presenting cells by down-regulating the class II transactivator CIITA. J Neuroimmunol (2003) 1.04
An automated in vitro protein folding screen applied to a human dynactin subunit. Protein Sci (2004) 1.03
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Ahnak is critical for cardiac Ca(V)1.2 calcium channel function and its beta-adrenergic regulation. FASEB J (2005) 1.02
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