PubRank

Peter Mundel

Author PubWeight™ 122.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 FGF23 induces left ventricular hypertrophy. J Clin Invest 2011 7.22
2 A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression. J Am Soc Nephrol 2002 6.48
3 Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med 2013 5.62
4 TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet 2005 5.53
5 The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat Med 2008 5.01
6 Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest 2004 4.65
7 Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton. Trends Cell Biol 2007 4.31
8 Modification of kidney barrier function by the urokinase receptor. Nat Med 2007 4.01
9 Gain-of-function RAF1 mutations cause Noonan and LEOPARD syndromes with hypertrophic cardiomyopathy. Nat Genet 2007 3.47
10 Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling. Nat Cell Biol 2006 3.31
11 Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis. J Am Soc Nephrol 2008 2.74
12 Cell biology and pathology of podocytes. Annu Rev Physiol 2011 2.42
13 Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner. J Clin Invest 2005 2.39
14 Activation of a local tissue angiotensin system in podocytes by mechanical strain. Kidney Int 2004 2.21
15 COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J Clin Invest 2011 2.21
16 Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes. Am J Pathol 2007 2.13
17 Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin. J Biol Chem 2004 2.10
18 Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity. Proc Natl Acad Sci U S A 2003 1.79
19 A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis. J Biol Chem 2004 1.70
20 Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin. J Clin Invest 2006 1.66
21 TGF-beta concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes. J Am Soc Nephrol 2005 1.61
22 The role of podocytes in glomerular pathobiology. Clin Exp Nephrol 2003 1.57
23 Stimulation of the calcium-sensing receptor stabilizes the podocyte cytoskeleton, improves cell survival, and reduces toxin-induced glomerulosclerosis. Kidney Int 2011 1.57
24 In response to protein load podocytes reorganize cytoskeleton and modulate endothelin-1 gene: implication for permselective dysfunction of chronic nephropathies. Am J Pathol 2005 1.54
25 Cross-reactivity of human lupus anti-DNA antibodies with alpha-actinin and nephritogenic potential. Arthritis Rheum 2005 1.41
26 Autocrine VEGF-A system in podocytes regulates podocin and its interaction with CD2AP. Am J Physiol Renal Physiol 2006 1.38
27 Co-localization of nephrin, podocin, and the actin cytoskeleton: evidence for a role in podocyte foot process formation. Am J Pathol 2002 1.34
28 Podocyte biology and the emerging understanding of podocyte diseases. Am J Nephrol 2003 1.31
29 The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells. Am J Physiol Renal Physiol 2008 1.31
30 Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes. Mol Cell Biol 2007 1.30
31 Danger signaling by glomerular podocytes defines a novel function of inducible B7-1 in the pathogenesis of nephrotic syndrome. J Am Soc Nephrol 2004 1.27
32 Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1. J Biol Chem 2002 1.26
33 Dynamic (re)organization of the podocyte actin cytoskeleton in the nephrotic syndrome. Pediatr Nephrol 2003 1.25
34 Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes. Kidney Int 2002 1.24
35 A WT1 co-regulator controls podocyte phenotype by shuttling between adhesion structures and nucleus. J Biol Chem 2004 1.23
36 Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3. J Cell Biol 2005 1.23
37 Nuclear relocation of the nephrin and CD2AP-binding protein dendrin promotes apoptosis of podocytes. Proc Natl Acad Sci U S A 2007 1.16
38 Inhibitory smads and tgf-Beta signaling in glomerular cells. J Am Soc Nephrol 2002 1.15
39 Mpv17l protects against mitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease. Proc Natl Acad Sci U S A 2008 1.13
40 Balancing calcium signals through TRPC5 and TRPC6 in podocytes. J Am Soc Nephrol 2011 1.11
41 Permselective dysfunction of podocyte-podocyte contact upon angiotensin II unravels the molecular target for renoprotective intervention. Am J Pathol 2006 1.10
42 Sp1 and Sp3 transcription factors synergistically regulate HGF receptor gene expression in kidney. Am J Physiol Renal Physiol 2003 1.08
43 Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids. Am J Physiol Renal Physiol 2010 1.07
44 A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development. J Am Soc Nephrol 2002 1.06
45 Formation and phosphorylation of the PINCH-1-integrin linked kinase-alpha-parvin complex are important for regulation of renal glomerular podocyte adhesion, architecture, and survival. J Am Soc Nephrol 2005 1.06
46 Tumor suppressor role for myopodin in bladder cancer: loss of nuclear expression of myopodin is cell-cycle dependent and predicts clinical outcome. Oncogene 2003 1.05
47 Role of nephrin in renal disease including diabetic nephropathy. Semin Nephrol 2002 1.03
48 Glomerular endothelial fenestrae in vivo are not formed from caveolae. J Am Soc Nephrol 2002 1.01
49 Calcium regulates podocyte actin dynamics. Semin Nephrol 2012 0.98
50 Role of angiotensin II in the development of nephropathy and podocytopathy of diabetes. Curr Diabetes Rev 2011 0.94
51 Yes-associated protein (YAP) promotes cell survival by inhibiting proapoptotic dendrin signaling. J Biol Chem 2013 0.94
52 Lamina-specific distribution of Synaptopodin, an actin-associated molecule essential for the spine apparatus, in identified principal cell dendrites of the mouse hippocampus. J Comp Neurol 2005 0.93
53 Role of 12-lipoxygenase in the stimulation of p38 mitogen-activated protein kinase and collagen alpha5(IV) in experimental diabetic nephropathy and in glucose-stimulated podocytes. J Am Soc Nephrol 2003 0.92
54 Role of altered insulin signaling pathways in the pathogenesis of podocyte malfunction and microalbuminuria. Curr Opin Nephrol Hypertens 2009 0.92
55 Differential expression of d-type cyclins in podocytes in vitro and in vivo. Am J Pathol 2004 0.92
56 Rescue of tropomyosin deficiency in Drosophila and human cancer cells by synaptopodin reveals a role of tropomyosin α in RhoA stabilization. EMBO J 2011 0.88
57 Dual effects of RAS blockade on blood pressure and podocyte function. Curr Hypertens Rep 2007 0.88
58 Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics. Nat Commun 2013 0.87
59 Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release. Diabetes 2009 0.87
60 Dynamin-mediated Nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells. J Biol Chem 2012 0.87
61 Inhibition of type I interferon signalling prevents TLR ligand-mediated proteinuria. J Pathol 2013 0.85
62 IFN-inducible protein-10 has a differential role in podocyte during Thy 1.1 glomerulonephritis. J Am Soc Nephrol 2003 0.85
63 Essential role for synaptopodin in dendritic spine plasticity of the developing hippocampus. J Neurosci 2013 0.84
64 Susceptibility of podocytes to palmitic acid is regulated by stearoyl-CoA desaturases 1 and 2. Am J Pathol 2013 0.84
65 Differentiation-induced cultured podocytes express endocytically active megalin, a heymann nephritis antigen. Nephron Exp Nephrol 2004 0.81
66 Novel concepts in understanding and management of glomerular proteinuria. Nephrol Dial Transplant 2002 0.80
67 Plasticity of synaptopodin and the spine apparatus organelle in the rat fascia dentata following entorhinal cortex lesion. J Comp Neurol 2006 0.80
68 Urinary podocytes: lost and found alive. Kidney Int 2003 0.80
69 Expression and regulation of adrenomedullin in renal glomerular podocytes. Biochem Biophys Res Commun 2005 0.79
70 Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med 2014 0.79
71 Short-term ischemia usually used for ischemic preconditioning causes loss of dendritic integrity after long-term survival in the gerbil hippocampus. Brain Res 2006 0.78
72 Susceptibility of podocytes to palmitic acid is regulated by fatty acid oxidation and inversely depends on acetyl-CoA carboxylases 1 and 2. Am J Physiol Renal Physiol 2013 0.78
73 Laminar distribution of synaptopodin in normal and reeler mouse brain depends on the position of spine-bearing neurons. J Comp Neurol 2002 0.76