Published in Matrix Biol on December 08, 2004
A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev Biol (2008) 1.79
Connecting muscles to tendons: tendons and musculoskeletal development in flies and vertebrates. Development (2010) 1.65
Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease. Dev Dyn (2010) 1.53
Rapid generation of mouse models with defined point mutations by the CRISPR/Cas9 system. Sci Rep (2014) 1.49
Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol (2009) 0.94
Degradome expression profiling in human articular cartilage. Arthritis Res Ther (2009) 0.93
The role of muscle cells in regulating cartilage matrix production. J Orthop Res (2010) 0.91
Transcriptional control of mesenchymal stem cell differentiation. Transfus Med Hemother (2008) 0.90
Mustn1 is expressed during chondrogenesis and is necessary for chondrocyte proliferation and differentiation in vitro. Bone (2009) 0.89
CCAAT/enhancer-binding protein β regulates the repression of type II collagen expression during the differentiation from proliferative to hypertrophic chondrocytes. J Biol Chem (2013) 0.89
Oestrogen blocks the nuclear entry of SOX9 in the developing gonad of a marsupial mammal. BMC Biol (2010) 0.87
E6-AP/UBE3A protein acts as a ubiquitin ligase toward SOX9 protein. J Biol Chem (2013) 0.85
The role of proteasome beta subunits in gastrin-mediated transcription of plasminogen activator inhibitor-2 and regenerating protein1. PLoS One (2013) 0.83
FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma. EMBO J (2016) 0.83
Transcriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cells. Mol Cell Biol (2006) 0.83
Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/β-catenin signaling. Oncotarget (2016) 0.80
Chondroitin Sulfate Immobilized on a Biomimetic Scaffold Modulates Inflammation While Driving Chondrogenesis. Stem Cells Transl Med (2016) 0.78
Loss of DDRGK1 modulates SOX9 ubiquitination in spondyloepimetaphyseal dysplasia. J Clin Invest (2017) 0.75
The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell (2002) 15.20
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev (2002) 8.19
Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev (2004) 4.78
Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors. Proc Natl Acad Sci U S A (2005) 4.25
SOX9 is required for the differentiation of paneth cells in the intestinal epithelium. Gastroenterology (2007) 4.17
NFAT and Osterix cooperatively regulate bone formation. Nat Med (2005) 2.99
Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest. Proc Natl Acad Sci U S A (2003) 2.64
Rare genetic variation at Zea mays crtRB1 increases beta-carotene in maize grain. Nat Genet (2010) 2.25
Genome-wide association study dissects the genetic architecture of oil biosynthesis in maize kernels. Nat Genet (2012) 2.25
Transcriptional mechanisms in osteoblast differentiation and bone formation. Trends Genet (2003) 2.23
Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice. Proc Natl Acad Sci U S A (2010) 2.20
Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype. Genes Dev (2004) 1.88
Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix. Proc Natl Acad Sci U S A (2008) 1.86
Genetic regulation of bone mass and susceptibility to osteoporosis. Genes Dev (2006) 1.86
p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling. J Cell Biol (2005) 1.86
Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa. Proc Natl Acad Sci U S A (2004) 1.77
Complete genome sequence of Paenibacillus polymyxa SC2, a strain of plant growth-promoting Rhizobacterium with broad-spectrum antimicrobial activity. J Bacteriol (2010) 1.76
FOXL2 and BPES: mutational hotspots, phenotypic variability, and revision of the genotype-phenotype correlation. Am J Hum Genet (2003) 1.70
Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis. Am J Pathol (2002) 1.68
Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis. Arthritis Rheum (2010) 1.64
The B subunit of the CCAAT box binding transcription factor complex (CBF/NF-Y) is essential for early mouse development and cell proliferation. Cancer Res (2003) 1.63
SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development (2010) 1.61
Cloacal exstrophy in an infant with 9q34.1-qter deletion resulting from a de novo unbalanced translocation between chromosome 9q and Yq. Am J Med Genet A (2004) 1.59
Positive regulation of adult bone formation by osteoblast-specific transcription factor osterix. J Bone Miner Res (2009) 1.56
CATSPER2, a human autosomal nonsyndromic male infertility gene. Eur J Hum Genet (2003) 1.54
Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase. EMBO J (2009) 1.54
Ubiquitination of E3 ubiquitin ligase TRIM5 alpha and its potential role. FEBS J (2008) 1.53
Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma. Arthritis Rheum (2007) 1.51
Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development (2009) 1.50
Sox9-expressing precursors are the cellular origin of the cruciate ligament of the knee joint and the limb tendons. Genesis (2010) 1.46
The consumption of low-mineral bottled water increases the risk of cardiovascular disease: an experimental study of rabbits and young men. Int J Cardiol (2013) 1.41
Mutations and sequence variants in GDF9 and BMP15 in patients with premature ovarian failure. Eur J Endocrinol (2006) 1.36
Generation of aggrecan-CreERT2 knockin mice for inducible Cre activity in adult cartilage. Genesis (2009) 1.31
The postnatal role of Sox9 in cartilage. J Bone Miner Res (2012) 1.31
CACTA-like transposable element in ZmCCT attenuated photoperiod sensitivity and accelerated the postdomestication spread of maize. Proc Natl Acad Sci U S A (2013) 1.31
Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice. J Biol Chem (2003) 1.29
Adjacent DNA sequences modulate Sox9 transcriptional activation at paired Sox sites in three chondrocyte-specific enhancer elements. Nucleic Acids Res (2003) 1.28
Ticks (acari: ixodoidea: argasidae, ixodidae) of China. Exp Appl Acarol (2010) 1.26
Genetic evidence for the vital function of Osterix in cementogenesis. J Bone Miner Res (2012) 1.26
Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation. Proc Natl Acad Sci U S A (2005) 1.26
Identification of SOX9 interaction sites in the genome of chondrocytes. PLoS One (2010) 1.26
β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis. Ann Rheum Dis (2012) 1.25
The new collagen gene COL27A1 contains SOX9-responsive enhancer elements. Matrix Biol (2005) 1.25
Improved immunodetection of endogenous α-synuclein. PLoS One (2011) 1.25
Cthrc1 is a positive regulator of osteoblastic bone formation. PLoS One (2008) 1.24
Interferon alfa down-regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice. Hepatology (2003) 1.24
Transcriptional regulation of chondrogenesis by coactivator Tip60 via chromatin association with Sox9 and Sox5. Nucleic Acids Res (2008) 1.23
Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice. J Am Coll Cardiol (2011) 1.23
Postnatally induced inactivation of Osterix in osteoblasts results in the reduction of bone formation and maintenance. Bone (2009) 1.23
Autoantigen Ro52 is an E3 ubiquitin ligase. Biochem Biophys Res Commun (2005) 1.23
Aetiological diagnosis of male sex ambiguity: a collaborative study. Eur J Pediatr (2002) 1.22
Sp1 and Sp3 transcription factors mediate interleukin-1 beta down-regulation of human type II collagen gene expression in articular chondrocytes. J Biol Chem (2003) 1.21
Molecular genetics of sex determination. Semin Reprod Med (2002) 1.18
Parkinson's disease-related protein, alpha-synuclein, in malignant melanoma. PLoS One (2010) 1.17
Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L. J Biol Chem (2003) 1.15
NUB1 suppresses the formation of Lewy body-like inclusions by proteasomal degradation of synphilin-1. Am J Pathol (2006) 1.14
Genetic investigation of four meiotic genes in women with premature ovarian failure. Eur J Endocrinol (2008) 1.13
The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1. Hum Mol Genet (2002) 1.12
Chondrocyte-specific ablation of Osterix leads to impaired endochondral ossification. Biochem Biophys Res Commun (2012) 1.11
Transgenic mice expressing a ligand-inducible cre recombinase in osteoblasts and odontoblasts: a new tool to examine physiology and disease of postnatal bone and tooth. Am J Pathol (2004) 1.11
Ro52-mediated monoubiquitination of IKK{beta} down-regulates NF-{kappa}B signalling. J Biochem (2009) 1.11
A Col9a1 enhancer element activated by two interdependent SOX9 dimers. Nucleic Acids Res (2007) 1.11
Interactions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9. J Biol Chem (2006) 1.10
NEDD8 protein is involved in ubiquitinated inclusion bodies. J Pathol (2003) 1.10
Cloning and characterization of a putative GS3 ortholog involved in maize kernel development. Theor Appl Genet (2009) 1.09
Osterix, a transcription factor for osteoblast differentiation, mediates antitumor activity in murine osteosarcoma. Cancer Res (2005) 1.09
Aberrant expression of ovary determining gene FOXL2 in the testis and juvenile granulosa cell tumor in children. J Urol (2008) 1.08
TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies. Neurobiol Dis (2010) 1.08
Specific expression of Cre recombinase in hypertrophic cartilage under the control of a BAC-Col10a1 promoter. Matrix Biol (2008) 1.08
Synthesis, characterization, and cytotoxicity of a novel highly charged trinuclear platinum compound. Enhancement of cellular uptake with charge. Inorg Chem (2005) 1.08
Relationship, evolutionary fate and function of two maize co-orthologs of rice GW2 associated with kernel size and weight. BMC Plant Biol (2010) 1.07
Familial occurrence of the IMAGe association: additional clinical variants and a proposed mode of inheritance. J Clin Endocrinol Metab (2005) 1.06
UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself. Biochem Biophys Res Commun (2006) 1.06
Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice. Matrix Biol (2006) 1.06
SOX9 exerts a bifunctional effect on type II collagen gene (COL2A1) expression in chondrocytes depending on the differentiation state. DNA Cell Biol (2003) 1.05
North African Jewish and non-Jewish populations form distinctive, orthogonal clusters. Proc Natl Acad Sci U S A (2012) 1.05
Dermal transforming growth factor-beta responsiveness mediates wound contraction and epithelial closure. Am J Pathol (2009) 1.05
Disruption of the principal, progesterone-activated sperm Ca2+ channel in a CatSper2-deficient infertile patient. Proc Natl Acad Sci U S A (2013) 1.05
Potential targets of FOXL2, a transcription factor involved in craniofacial and follicular development, identified by transcriptomics. Proc Natl Acad Sci U S A (2007) 1.05
Inhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapy. Mol Oncol (2012) 1.05
Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice. Mech Dev (2009) 1.05
Genome-wide association studies identified three independent polymorphisms associated with α-tocopherol content in maize kernels. PLoS One (2012) 1.04
An evolutionary and functional analysis of FoxL2 in rainbow trout gonad differentiation. J Mol Endocrinol (2004) 1.04
Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a). J Lipid Res (2013) 1.04
Genetic male infertility and mutation of CATSPER ion channels. Eur J Hum Genet (2010) 1.03
Transcriptional regulation of Vascular Endothelial Growth Factor (VEGF) by osteoblast-specific transcription factor Osterix (Osx) in osteoblasts. J Biol Chem (2011) 1.03
Connective tissue growth factor causes EMT-like cell fate changes in vivo and in vitro. J Cell Sci (2013) 1.03
Extinction of FOXL2 expression in aggressive ovarian granulosa cell tumors in children. Fertil Steril (2007) 1.02
Genome-wide analysis of ZmDREB genes and their association with natural variation in drought tolerance at seedling stage of Zea mays L. PLoS Genet (2013) 1.01
Role of the NF-kappaB signaling pathway and kappaB cis-regulatory elements on the IRF-1 and iNOS promoter regions in mycobacterial lipoarabinomannan induction of nitric oxide. Infect Immun (2003) 1.00
Functional exploration of the adult ovarian granulosa cell tumor-associated somatic FOXL2 mutation p.Cys134Trp (c.402C>G). PLoS One (2010) 1.00
Novel paralogy relations among human chromosomes support a link between the phylogeny of doublesex-related genes and the evolution of sex determination. Genomics (2002) 0.99
SOX9 mediates the retinoic acid-induced HES-1 gene expression in human breast cancer cells. Breast Cancer Res Treat (2009) 0.99
Mangiferin attenuates osteoclastogenesis, bone resorption, and RANKL-induced activation of NF-κB and ERK. J Cell Biochem (2011) 0.98
Sclerostin is a direct target of osteoblast-specific transcription factor osterix. Biochem Biophys Res Commun (2010) 0.98
Altered mandibular development precedes the time of palate closure in mice homozygous for disproportionate micromelia: an oral clefting model supporting the Pierre-Robin sequence. Teratology (2002) 0.97
SOX9 directly regulates IGFBP-4 in the intestinal epithelium. Am J Physiol Gastrointest Liver Physiol (2013) 0.97
Genetic basis of grain yield heterosis in an "immortalized F₂" maize population. Theor Appl Genet (2014) 0.97