Published in Mol Biochem Parasitol on March 01, 2005
Functional anthology of intrinsic disorder. 2. Cellular components, domains, technical terms, developmental processes, and coding sequence diversities correlated with long disordered regions. J Proteome Res (2007) 1.48
The origins of apicomplexan sequence innovation. Genome Res (2009) 1.03
In silico identification of specialized secretory-organelle proteins in apicomplexan parasites and in vivo validation in Toxoplasma gondii. PLoS One (2008) 0.95
Subcompartmentalisation of proteins in the rhoptries correlates with ordered events of erythrocyte invasion by the blood stage malaria parasite. PLoS One (2012) 0.94
Novel putative glycosylphosphatidylinositol-anchored micronemal antigen of Plasmodium falciparum that binds to erythrocytes. Eukaryot Cell (2009) 0.93
Characterization of a conserved rhoptry-associated leucine zipper-like protein in the malaria parasite Plasmodium falciparum. Infect Immun (2008) 0.90
Plasmodium falciparum Pf34, a novel GPI-anchored rhoptry protein found in detergent-resistant microdomains. Int J Parasitol (2007) 0.88
Identification of a new rhoptry neck complex RON9/RON10 in the Apicomplexa parasite Toxoplasma gondii. PLoS One (2012) 0.83
Identification, characterization and antigenicity of the Plasmodium vivax rhoptry neck protein 1 (PvRON1). Malar J (2011) 0.78
A proteomic view of the Plasmodium falciparum life cycle. Nature (2002) 10.65
Discovery of gene function by expression profiling of the malaria parasite life cycle. Science (2003) 10.57
Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle. Genome Res (2004) 3.63
Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum. Nat Chem Biol (2008) 3.16
A conserved molecular motor drives cell invasion and gliding motility across malaria life cycle stages and other apicomplexan parasites. J Biol Chem (2005) 2.50
Fine specificity of serum antibodies to Plasmodium falciparum merozoite surface protein, PfMSP-1(19), predicts protection from malaria infection and high-density parasitemia. Infect Immun (2004) 2.31
Profiling the antibody immune response against blood stage malaria vaccine candidates. Clin Chem (2007) 2.23
A role for the protease falcipain 1 in host cell invasion by the human malaria parasite. Science (2002) 2.20
The motor complex of Plasmodium falciparum: phosphorylation by a calcium-dependent protein kinase. J Biol Chem (2008) 2.14
Effective induction of high-titer antibodies by viral vector vaccines. Nat Med (2008) 1.76
Molecules incorporating a benzothiazole core scaffold inhibit the N-myristoyltransferase of Plasmodium falciparum. Biochem J (2007) 1.75
Variation in the expression of a Plasmodium falciparum protein family implicated in erythrocyte invasion. Infect Immun (2002) 1.64
Epigenetic silencing of Plasmodium falciparum genes linked to erythrocyte invasion. PLoS Pathog (2007) 1.63
The importance of human FcgammaRI in mediating protection to malaria. PLoS Pathog (2007) 1.61
The human immune response to Plasmodium falciparum includes both antibodies that inhibit merozoite surface protein 1 secondary processing and blocking antibodies. Infect Immun (2002) 1.56
Malaria parasite actin filaments are very short. J Mol Biol (2005) 1.56
Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites. PLoS Genet (2012) 1.55
Dual acylation of the 45 kDa gliding-associated protein (GAP45) in Plasmodium falciparum merozoites. Mol Biochem Parasitol (2006) 1.53
Function of region I and II adhesive motifs of Plasmodium falciparum circumsporozoite protein in sporozoite motility and infectivity. J Biol Chem (2002) 1.50
The fine specificity, but not the invasion inhibitory activity, of 19-kilodalton merozoite surface protein 1-specific antibodies is associated with resistance to malarial parasitemia in a cross-sectional survey in The Gambia. Infect Immun (2004) 1.44
The malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony. Eukaryot Cell (2009) 1.39
Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs. PLoS Negl Trop Dis (2012) 1.36
N-myristoyltransferase: a prospective drug target for protozoan parasites. ChemMedChem (2008) 1.33
A comprehensive evaluation of rodent malaria parasite genomes and gene expression. BMC Biol (2014) 1.31
Identification of a stomatin orthologue in vacuoles induced in human erythrocytes by malaria parasites. A role for microbial raft proteins in apicomplexan vacuole biogenesis. J Biol Chem (2003) 1.27
Apical expression of three RhopH1/Clag proteins as components of the Plasmodium falciparum RhopH complex. Mol Biochem Parasitol (2005) 1.26
Site-specific N-terminal labelling of proteins in vitro and in vivo using N-myristoyl transferase and bioorthogonal ligation chemistry. Chem Commun (Camb) (2007) 1.25
Adaptation of the genetically tractable malaria pathogen Plasmodium knowlesi to continuous culture in human erythrocytes. Proc Natl Acad Sci U S A (2012) 1.24
Identification of new PNEPs indicates a substantial non-PEXEL exportome and underpins common features in Plasmodium falciparum protein export. PLoS Pathog (2013) 1.24
Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5. J Immunol (2013) 1.22
Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1. PLoS One (2011) 1.22
The MTIP-myosin A complex in blood stage malaria parasites. J Mol Biol (2005) 1.20
PSLAP, a protein with multiple adhesive motifs, is expressed in Plasmodium falciparum gametocytes. Mol Biochem Parasitol (2002) 1.20
Protective immune responses to the 42-kilodalton (kDa) region of Plasmodium yoelii merozoite surface protein 1 are induced by the C-terminal 19-kDa region but not by the adjacent 33-kDa region. Infect Immun (2002) 1.19
Formation of the food vacuole in Plasmodium falciparum: a potential role for the 19 kDa fragment of merozoite surface protein 1 (MSP1(19)). PLoS One (2008) 1.18
The Plasmodium falciparum clag9 gene encodes a rhoptry protein that is transferred to the host erythrocyte upon invasion. Mol Microbiol (2004) 1.17
Merozoite surface proteins of the malaria parasite: the MSP1 complex and the MSP7 family. Int J Parasitol (2010) 1.17
Extensive proteolytic processing of the malaria parasite merozoite surface protein 7 during biosynthesis and parasite release from erythrocytes. Mol Biochem Parasitol (2006) 1.11
Discovery of Plasmodium vivax N-myristoyltransferase inhibitors: screening, synthesis, and structural characterization of their binding mode. J Med Chem (2012) 1.09
Plasmodium falciparum STEVOR proteins are highly expressed in patient isolates and located in the surface membranes of infected red blood cells and the apical tips of merozoites. Infect Immun (2008) 1.07
Malaria parasite actin polymerization and filament structure. J Biol Chem (2010) 1.06
Novel antimalarial antibodies highlight the importance of the antibody Fc region in mediating protection. Blood (2003) 1.05
Comparative testing of six antigen-based malaria vaccine candidates directed toward merozoite-stage Plasmodium falciparum. Clin Vaccine Immunol (2008) 1.05
Identification and characterization of the Plasmodium yoelii PyP140/RON4 protein, an orthologue of Toxoplasma gondii RON4, whose cysteine-rich domain does not protect against lethal parasite challenge infection. Infect Immun (2008) 1.05
Structural studies on Plasmodium vivax merozoite surface protein-1. Mol Biochem Parasitol (2007) 1.04
The oligomerization domain of C4-binding protein (C4bp) acts as an adjuvant, and the fusion protein comprised of the 19-kilodalton merozoite surface protein 1 fused with the murine C4bp domain protects mice against malaria. Infect Immun (2008) 1.04
Design and synthesis of inhibitors of Plasmodium falciparum N-myristoyltransferase, a promising target for antimalarial drug discovery. J Med Chem (2012) 1.03
The Plasmodium falciparum schizont phosphoproteome reveals extensive phosphatidylinositol and cAMP-protein kinase A signaling. J Proteome Res (2012) 1.03
Subcellular location, phosphorylation and assembly into the motor complex of GAP45 during Plasmodium falciparum schizont development. PLoS One (2012) 1.01
Inducible knockdown of Plasmodium gene expression using the glmS ribozyme. PLoS One (2013) 1.01
Diversity covering AMA1-MSP119 fusion proteins as malaria vaccines. Infect Immun (2013) 1.00
Passive immunization with a multicomponent vaccine against conserved domains of apical membrane antigen 1 and 235-kilodalton rhoptry proteins protects mice against Plasmodium yoelii blood-stage challenge infection. Infect Immun (2006) 1.00
Plasmodium thrombospondin related apical merozoite protein (PTRAMP) is shed from the surface of merozoites by PfSUB2 upon invasion of erythrocytes. Mol Biochem Parasitol (2006) 1.00
Suramin and suramin analogues inhibit merozoite surface protein-1 secondary processing and erythrocyte invasion by the malaria parasite Plasmodium falciparum. J Biol Chem (2003) 0.99
Characterisation of the rhoph2 gene of Plasmodium falciparum and Plasmodium yoelii. Mol Biochem Parasitol (2003) 0.97
Disruption of Plasmodium berghei merozoite surface protein 7 gene modulates parasite growth in vivo. Blood (2004) 0.97
Deletion of the Plasmodium falciparum merozoite surface protein 7 gene impairs parasite invasion of erythrocytes. Eukaryot Cell (2008) 0.97
A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion. PLoS Pathog (2012) 0.97
Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite. Biol Open (2013) 0.96
An ancient protein phosphatase, SHLP1, is critical to microneme development in Plasmodium ookinetes and parasite transmission. Cell Rep (2013) 0.95
Discovery of novel and ligand-efficient inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferase. J Med Chem (2012) 0.95
Design and synthesis of high affinity inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferases directed by ligand efficiency dependent lipophilicity (LELP). J Med Chem (2014) 0.95
Plasmodium falciparum 19-kilodalton merozoite surface protein 1 (MSP1)-specific antibodies that interfere with parasite growth in vitro can inhibit MSP1 processing, merozoite invasion, and intracellular parasite development. Infect Immun (2011) 0.94
Immunoglobulin G antibodies to merozoite surface antigens are associated with recovery from chloroquine-resistant Plasmodium falciparum in Gambian children. Infect Immun (2006) 0.94
Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surface protein-1(19) mapped by TROSY NMR. Mol Biochem Parasitol (2004) 0.93
Loss of protein kinase Calpha expression may enhance the tumorigenic potential of Gli1 in basal cell carcinoma. Cancer Res (2003) 0.93
Novel putative glycosylphosphatidylinositol-anchored micronemal antigen of Plasmodium falciparum that binds to erythrocytes. Eukaryot Cell (2009) 0.93
The mechanism of erythrocyte invasion by the malarial parasite, Plasmodium falciparum. Semin Cell Dev Biol (2011) 0.93
The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes. PLoS One (2010) 0.92
Calcium dependent protein kinase 1 and calcium fluxes in the malaria parasite. Microbes Infect (2012) 0.92
GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytes. Carcinogenesis (2008) 0.92
Human red blood cell-adapted Plasmodium knowlesi parasites: a new model system for malaria research. Cell Microbiol (2014) 0.91