Published in Vaccine on February 18, 2005
Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns. Nat Rev Immunol (2010) 4.06
Molecular and cellular signatures of human vaccine adjuvants. Proc Natl Acad Sci U S A (2008) 2.02
Inflammasomes: current understanding and open questions. Cell Mol Life Sci (2010) 1.87
Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88. Proc Natl Acad Sci U S A (2011) 1.44
Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants. Proc Natl Acad Sci U S A (2014) 1.36
Classification and characterization of therapeutic antibody aggregates. J Biol Chem (2011) 1.28
Immune mechanisms of protection: can adjuvants rise to the challenge? BMC Biol (2010) 1.22
Mechanism of immunopotentiation and safety of aluminum adjuvants. Front Immunol (2013) 1.13
Formulation of vaccines containing CpG oligonucleotides and alum. J Immunol Methods (2007) 1.11
Synthetic Nanoparticles for Vaccines and Immunotherapy. Chem Rev (2015) 1.10
Recent progress in adjuvant discovery for peptide-based subunit vaccines. Hum Vaccin Immunother (2013) 1.10
Highly aggregated antibody therapeutics can enhance the in vitro innate and late-stage T-cell immune responses. J Biol Chem (2012) 1.09
Slow CCL2-dependent translocation of biopersistent particles from muscle to brain. BMC Med (2013) 1.09
Mechanisms of action of adjuvants. Front Immunol (2013) 1.05
Local response to microneedle-based influenza immunization in the skin. MBio (2012) 1.03
Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro. Immunol Lett (2012) 1.01
Variation of the specificity of the human antibody responses after tick-borne encephalitis virus infection and vaccination. J Virol (2014) 1.00
Aggregation of human recombinant monoclonal antibodies influences the capacity of dendritic cells to stimulate adaptive T-cell responses in vitro. PLoS One (2014) 0.99
Engineering an effective immune adjuvant by designed control of shape and crystallinity of aluminum oxyhydroxide nanoparticles. ACS Nano (2013) 0.99
Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses. Int Immunol (2008) 0.94
Macrophagic myofasciitis: characterization and pathophysiology. Lupus (2012) 0.91
Vaccines with aluminum-containing adjuvants: optimizing vaccine efficacy and thermal stability. J Pharm Sci (2010) 0.91
Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts. Crit Rev Toxicol (2014) 0.90
Micrometer-sized titanium particles can induce potent Th2-type responses through TLR4-independent pathways. J Immunol (2011) 0.89
Stabilization of a recombinant ricin toxin A subunit vaccine through lyophilization. Eur J Pharm Biopharm (2013) 0.88
Aluminum hydroxide nanoparticles show a stronger vaccine adjuvant activity than traditional aluminum hydroxide microparticles. J Control Release (2013) 0.88
TRIF is a critical negative regulator of TLR agonist mediated activation of dendritic cells in vivo. PLoS One (2011) 0.85
Impact of antibody quality and anamnestic response on viremia control post-challenge in a combined Tat/Env vaccine regimen in rhesus macaques. Virology (2013) 0.83
Anthrax sub-unit vaccine: the structural consequences of binding rPA83 to Alhydrogel®. Eur J Pharm Biopharm (2011) 0.82
Formulation of a killed whole cell pneumococcus vaccine - effect of aluminum adjuvants on the antibody and IL-17 response. J Immune Based Ther Vaccines (2011) 0.80
The mechanisms of action of vaccines containing aluminum adjuvants: an in vitro vs in vivo paradigm. Springerplus (2015) 0.80
Powerful Complex Immunoadjuvant Based on Synergistic Effect of Combined TLR4 and NOD2 Activation Significantly Enhances Magnitude of Humoral and Cellular Adaptive Immune Responses. PLoS One (2016) 0.80
Enhanced specific immune responses by CpG DNA in mice immunized with recombinant hepatitis B surface antigen and HB vaccine. Virol J (2011) 0.79
Vaccine self-assembling immune matrix is a new delivery platform that enhances immune responses to recombinant HBsAg in mice. Clin Vaccine Immunol (2015) 0.78
Malaria vaccine adjuvants: latest update and challenges in preclinical and clinical research. Biomed Res Int (2013) 0.78
Aluminum hydroxide influences not only the extent but also the fine specificity and functional activity of antibody responses to tick-borne encephalitis virus in mice. J Virol (2013) 0.78
Silica nanoparticles as the adjuvant for the immunisation of mice using hepatitis B core virus-like particles. PLoS One (2014) 0.78
A CpG-containing oligodeoxynucleotide adjuvant for acellular pertussis vaccine improves the protective response against Bordetella pertussis. Hum Vaccin Immunother (2013) 0.77
The effect of TLR9 agonist CpG oligodeoxynucleotides on the intestinal immune response of cobia (Rachycentron canadum). J Immunol Res (2014) 0.76
Patterns of binding of aluminum-containing adjuvants to Haemophilus influenzae type b and meningococcal group C conjugate vaccines and components. Biologicals (2015) 0.76
Vaccinology: The art of putting together the right ingredients. Hum Vaccin Immunother (2016) 0.75
From Stock Bottle to Vaccine: Elucidating the Particle Size Distributions of Aluminum Adjuvants Using Dynamic Light Scattering. Front Chem (2017) 0.75
A rational, systematic approach for the development of vaccine formulations. AAPS J (2011) 0.75
Biopersistence and brain translocation of aluminum adjuvants of vaccines. Front Neurol (2015) 0.75
Fc receptors and their influence on efficacy of therapeutic antibodies for treatment of viral diseases. Expert Rev Anti Infect Ther (2015) 0.75
Porcine Dendritic Cells as an In Vitro Model to Assess the Immunological Behaviour of Streptococcus suis Subunit Vaccine Formulations and the Polarizing Effect of Adjuvants. Pathogens (2017) 0.75
Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J Biol Chem (2002) 4.48
TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria. Cell (2012) 4.44
Tensile mechanical properties of three-dimensional type I collagen extracellular matrices with varied microstructure. J Biomech Eng (2002) 3.48
A cellular Trojan Horse for delivery of therapeutic nanoparticles into tumors. Nano Lett (2007) 2.08
Bacteria-mediated delivery of nanoparticles and cargo into cells. Nat Nanotechnol (2007) 1.83
Activation of dendritic cells and induction of CD4(+) T cell differentiation by aluminum-containing adjuvants. Vaccine (2007) 1.76
Cytokine expression in normal and inflamed esophageal mucosa: a study into the pathogenesis of allergic eosinophilic esophagitis. J Pediatr Gastroenterol Nutr (2006) 1.56
Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis. Blood (2008) 1.52
The influence of exercise training on inflammatory cytokines and C-reactive protein. Med Sci Sports Exerc (2007) 1.50
Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis. Blood (2009) 1.48
Retinoic acid determines the precise tissue tropism of inflammatory Th17 cells in the intestine. J Immunol (2010) 1.39
'Living cantilever arrays' for characterization of mass of single live cells in fluids. Lab Chip (2008) 1.39
Phagocytosis and phagosome acidification are required for pathogen processing and MyD88-dependent responses to Staphylococcus aureus. J Immunol (2010) 1.38
Subject classification obtained by cluster analysis and principal component analysis applied to flow cytometric data. Cytometry A (2007) 1.28
Label-free detection of multiple bacterial pathogens using light-scattering sensor. Biosens Bioelectron (2008) 1.25
Relationship between the strength of antigen adsorption to an aluminum-containing adjuvant and the immune response. Vaccine (2007) 1.19
Hyperspectral cytometry at the single-cell level using a 32-channel photodetector. Cytometry A (2011) 1.18
Influence of exercise training and age on CD14+ cell-surface expression of toll-like receptor 2 and 4. Brain Behav Immun (2005) 1.16
Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress. Neurochem Int (2005) 1.13
Optical forward-scattering for detection of Listeria monocytogenes and other Listeria species. Biosens Bioelectron (2006) 1.13
Physical activity status, but not age, influences inflammatory biomarkers and toll-like receptor 4. J Gerontol A Biol Sci Med Sci (2006) 1.13
Potentiation of the immune response to non-adsorbed antigens by aluminum-containing adjuvants. Vaccine (2006) 1.11
Automated classification of bacterial particles in flow by multiangle scatter measurement and support vector machine classifier. Cytometry A (2008) 1.09
Composite surface for blocking bacterial adsorption on protein biochips. Biotechnol Bioeng (2003) 1.07
Local, three-dimensional strain measurements within largely deformed extracellular matrix constructs. J Biomech Eng (2004) 1.07
DPI induces mitochondrial superoxide-mediated apoptosis. Free Radic Biol Med (2003) 1.05
Compression of fluorescence microscopy images based on the signal-to-noise estimation. Microsc Res Tech (2006) 1.04
Phi29 pRNA vector for efficient escort of hammerhead ribozyme targeting survivin in multiple cancer cells. Cancer Biol Ther (2007) 1.04
Simultaneous mechanical loading and confocal reflection microscopy for three-dimensional microbiomechanical analysis of biomaterials and tissue constructs. Microsc Microanal (2003) 1.02
Porcine circovirus type 2 (PCV2) causes apoptosis in experimentally inoculated BALB/c mice. BMC Vet Res (2005) 1.02
Comparative analysis of vector biodistribution, persistence and gene expression following intravenous delivery of bovine, porcine and human adenoviral vectors in a mouse model. Virology (2009) 1.02
Discovering the unknown: detection of emerging pathogens using a label-free light-scattering system. Cytometry A (2010) 1.00
Imject Alum is not aluminum hydroxide adjuvant or aluminum phosphate adjuvant. Vaccine (2007) 1.00
Developing a comprehensive mouse pathology program. Comp Med (2004) 0.99
Mechanism of immunopotentiation by aluminum-containing adjuvants elucidated by the relationship between antigen retention at the inoculation site and the immune response. Vaccine (2010) 0.98
Biophysical modeling of forward scattering from bacterial colonies using scalar diffraction theory. Appl Opt (2007) 0.98
Training mouse pathologists: five years of pathology of mouse models of human disease workshops. Toxicol Pathol (2007) 0.97
Investigations of phagosomes, mitochondria, and acidic granules in human neutrophils using fluorescent probes. Cytometry B Clin Cytom (2003) 0.97
Feature extraction from light-scatter patterns of Listeria colonies for identification and classification. J Biomed Opt (2006) 0.97
Effect of the strength of adsorption of hepatitis B surface antigen to aluminum hydroxide adjuvant on the immune response. Vaccine (2008) 0.96
Induction of antigen-specific Th1-type immune responses by gamma-irradiated recombinant Brucella abortus RB51. Clin Diagn Lab Immunol (2005) 0.96
Measuring the surface area of aluminum hydroxide adjuvant. J Pharm Sci (2002) 0.94
Relationship between the degree of antigen adsorption to aluminum hydroxide adjuvant in interstitial fluid and antibody production. Vaccine (2003) 0.94
SHARPIN is essential for cytokine production, NF-κB signaling, and induction of Th1 differentiation by dendritic cells. PLoS One (2012) 0.94
Laser optical sensor, a label-free on-plate Salmonella enterica colony detection tool. MBio (2014) 0.93
Effect of the degree of phosphate substitution in aluminum hydroxide adjuvant on the adsorption of phosphorylated proteins. Pharm Dev Technol (2003) 0.92
Quadratic form: a robust metric for quantitative comparison of flow cytometric histograms. Cytometry A (2008) 0.92
Modeling light propagation through bacterial colonies and its correlation with forward scattering patterns. J Biomed Opt (2010) 0.92
Confocal fluorescence imaging of photosensitized DNA denaturation in cell nuclei. Photochem Photobiol (2005) 0.91
Light-scattering sensor for real-time identification of Vibrio parahaemolyticus, Vibrio vulnificus and Vibrio cholerae colonies on solid agar plate. Microb Biotechnol (2012) 0.90
Analysis of orientations of collagen fibers by novel fiber-tracking software. Microsc Microanal (2003) 0.90
Effect of microenvironment pH of aluminum hydroxide adjuvant on the chemical stability of adsorbed antigen. Vaccine (2004) 0.90
The effect of surface charge and partition coefficient on the chemical stability of solutes in O/W emulsions. J Pharm Sci (2002) 0.89
Mechanism of adsorption of hepatitis B surface antigen by aluminum hydroxide adjuvant. Vaccine (2004) 0.89
Dectin-1 activation controls maturation of β-1,3-glucan-containing phagosomes. J Biol Chem (2013) 0.88
An excitation wavelength-scanning spectral imaging system for preclinical imaging. Rev Sci Instrum (2008) 0.87
Analysis of time-resolved scattering from macroscale bacterial colonies. J Biomed Opt (2008) 0.86
Absolute CD4+ cell count using a plastic microchip and a microscopic cell counter. Cytometry B Clin Cytom (2009) 0.86
Loss of image quality in photobleaching during microscopic imaging of fluorescent probes bound to chromatin. J Biomed Opt (2006) 0.86
Structure and adsorption properties of commercial calcium phosphate adjuvant. Vaccine (2004) 0.86
Distribution of adsorbed antigen in mono-valent and combination vaccines. Vaccine (2004) 0.86
Phenotypic profiling of Raf inhibitors and mitochondrial toxicity in 3D tissue using biodynamic imaging. J Biomol Screen (2013) 0.83
Comparative three-dimensional imaging of living neurons with confocal and atomic force microscopy. J Neurosci Methods (2005) 0.83
Relationship of adsorption mechanism of antigens by aluminum-containing adjuvants to in vitro elution in interstitial fluid. Vaccine (2005) 0.83
Adverse vaccinal events in dogs and cats. Vet Clin North Am Small Anim Pract (2010) 0.83
Effect of phosphorylation of ovalbumin on adsorption by aluminum-containing adjuvants and elution upon exposure to interstitial fluid. Vaccine (2005) 0.82
Development of a microbial high-throughput screening instrument based on elastic light scatter patterns. Rev Sci Instrum (2012) 0.82
Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors. PLoS One (2013) 0.81
Microenvironment-controlled encapsulation (MiCE) process: effects of PLGA concentration, flow rate, and collection method on microcapsule size and morphology. Pharm Res (2007) 0.81
Preformulation studies--The next advance in aluminum adjuvant-containing vaccines. Vaccine (2010) 0.81
Formulation of a killed whole cell pneumococcus vaccine - effect of aluminum adjuvants on the antibody and IL-17 response. J Immune Based Ther Vaccines (2011) 0.80
Determination of methylparaben in o/w emulsions by solid-phase extraction and high-performance liquid chromatography. J Cosmet Sci (2003) 0.80
Integrating cytomics and proteomics. Mol Cell Proteomics (2005) 0.80
Adaptive image-processing technique and effective visualization of confocal microscopy images. Microsc Res Tech (2004) 0.79
Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters. J Biol Chem (2010) 0.79
Differential mitochondrial toxicity screening and multi-parametric data analysis. PLoS One (2012) 0.79
Mouse and human islets survive and function after coating by biosilicification. Am J Physiol Endocrinol Metab (2013) 0.79
Evaluation of antithyroglobulin antibodies after routine vaccination in pet and research dogs. J Am Vet Med Assoc (2002) 0.79
Vascular-associated lymphoid tissue in swine (Sus scrofa). Comp Med (2008) 0.79
AFM/CLSM data visualization and comparison using an open-source toolkit. Microsc Res Tech (2004) 0.79
Effect of the strength of adsorption of HIV 1 SF162dV2gp140 to aluminum-containing adjuvants on the immune response. J Pharm Sci (2011) 0.79
Aluminum hydroxide adjuvant produced under constant reactant concentration. J Pharm Sci (2006) 0.78
Lack of association between repeated vaccination and thyroiditis in laboratory Beagles. J Vet Intern Med (2006) 0.78
A NUP98-HOXD13 leukemic fusion gene leads to impaired class switch recombination and antibody production. Exp Hematol (2012) 0.78
A Machine-Learning Approach to Detecting Unknown Bacterial Serovars. Stat Anal Data Min (2010) 0.78
Effects of cellulose derivatives and poly(ethylene oxide)-poly(propylene oxide) tri-block copolymers (Pluronic)surfactants) on the properties of alginate based microspheres and their interactions with phagocytic cells. J Control Release (2002) 0.77