Published in PLoS One on May 17, 2016
Safety and immunogenicity of GamEvac-Combi, a heterologous VSV- and Ad5-vectored Ebola vaccine: An open phase I/II trial in healthy adults in Russia. Hum Vaccin Immunother (2017) 0.76
Chlamydial Type III Secretion System Needle Protein Induces Protective Immunity against Chlamydia muridarum Intravaginal Infection. Biomed Res Int (2017) 0.75
Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics (2003) 100.88
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science (1998) 37.15
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature (1997) 23.92
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med (1992) 22.13
Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu Rev Immunol (1994) 8.43
Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol (2007) 7.23
Control of B-cell responses by Toll-like receptors. Nature (2005) 6.44
Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. Annu Rev Immunol (1997) 5.95
Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction. Nature (2006) 5.19
Vaccine adjuvants: putting innate immunity to work. Immunity (2010) 5.02
Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells. Immunity (2007) 4.70
Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester. Nat Protoc (2007) 3.45
Chemokines and chemokine receptors: positioning cells for host defense and immunity. Annu Rev Immunol (2014) 2.71
Key roles of adjuvants in modern vaccines. Nat Med (2013) 2.62
Transport of peptide-MHC class II complexes in developing dendritic cells. Science (2000) 2.62
The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands. Immunity (2008) 2.53
Aluminium hydroxide adjuvant initiates strong antigen-specific Th2 responses in the absence of IL-4- or IL-13-mediated signaling. J Immunol (1999) 2.53
AS04, an aluminum salt- and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity. J Immunol (2009) 2.49
Toll-like receptors: linking innate and adaptive immunity. Microbes Infect (2004) 2.38
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity (2007) 2.15
TLR-based immune adjuvants. Vaccine (2010) 2.10
Vaccine adjuvants alter TCR-based selection thresholds. Immunity (2008) 2.10
Induction of systemic TH1-like innate immunity in normal volunteers following subcutaneous but not intravenous administration of CPG 7909, a synthetic B-class CpG oligodeoxynucleotide TLR9 agonist. J Immunother (2004) 2.02
Nod2-dependent Th2 polarization of antigen-specific immunity. J Immunol (2008) 1.78
Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses. J Immunol (2005) 1.75
Signaling mechanisms in the antimicrobial host defense of Drosophila. Curr Opin Microbiol (2000) 1.69
Interleukin-12 profoundly up-regulates the synthesis of antigen-specific complement-fixing IgG2a, IgG2b and IgG3 antibody subclasses in vivo. Eur J Immunol (1995) 1.68
Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements. PLoS One (2008) 1.65
Controlling the Toll road to dendritic cell polarization. J Leukoc Biol (2004) 1.60
Role of aluminum-containing adjuvants in antigen internalization by dendritic cells in vitro. Vaccine (2005) 1.51
Critical role of NOD2 in regulating the immune response to Staphylococcus aureus. Infect Immun (2009) 1.49
Signaling pathways in phagocytosis. Bioessays (1999) 1.40
Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK-STAT. Proc Natl Acad Sci U S A (2005) 1.39
Responses to the soluble flagellar protein FliC are Th2, while those to FliC on Salmonella are Th1. Eur J Immunol (2004) 1.38
Synergistic enhancement of Toll-like receptor responses by NOD1 activation. Eur J Immunol (2005) 1.37
Bacterial lipoprotein induces resistance to Gram-negative sepsis in TLR4-deficient mice via enhanced bacterial clearance. J Immunol (2005) 1.09
Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells. Immunology (2008) 1.08
FADD negatively regulates lipopolysaccharide signaling by impairing interleukin-1 receptor-associated kinase 1-MyD88 interaction. Mol Cell Biol (2007) 1.04
The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling. PLoS One (2013) 1.02
Noncoding RNA danger motifs bridge innate and adaptive immunity and are potent adjuvants for vaccination. J Clin Invest (2002) 0.99
A TLR2 agonist is a more effective adjuvant for a Chlamydia major outer membrane protein vaccine than ligands to other TLR and NOD receptors. Vaccine (2011) 0.92
TLR4 mediates MAPK-STAT3 axis activation in bladder epithelial cells. Inflammation (2013) 0.87
Apoptotic effects of LPS on fibroblasts are indirectly mediated through TNFR1. J Dent Res (2004) 0.86
Combined stimulation of Toll-like receptor 5 and NOD1 strongly potentiates activity of NF-κB, resulting in enhanced innate immune reactions and resistance to Salmonella enterica serovar Typhimurium infection. Infect Immun (2013) 0.83
A Novel Prime and Boost Regimen of HIV Virus-Like Particles with TLR4 Adjuvant MPLA Induces Th1 Oriented Immune Responses against HIV. PLoS One (2015) 0.77