Published in Biophys J on February 04, 2005
Inorganic polyphosphate modulates TRPM8 channels. PLoS One (2009) 1.64
The mitochondrial permeability transition pore: a mystery solved? Front Physiol (2013) 1.57
Phosphate is essential for inhibition of the mitochondrial permeability transition pore by cyclosporin A and by cyclophilin D ablation. J Biol Chem (2008) 1.43
Targeted polyphosphatase expression alters mitochondrial metabolism and inhibits calcium-dependent cell death. Proc Natl Acad Sci U S A (2007) 1.38
The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology. Physiol Rev (2015) 1.31
Inorganic polyphosphate and energy metabolism in mammalian cells. J Biol Chem (2010) 1.30
Haemophilus influenzae outer membrane protein P5 is associated with inorganic polyphosphate and polyhydroxybutyrate. Biophys J (2006) 1.26
Polyphosphate--an ancient energy source and active metabolic regulator. Microb Cell Fact (2011) 1.19
Polyphosphate kinase 1, a conserved bacterial enzyme, in a eukaryote, Dictyostelium discoideum, with a role in cytokinesis. Proc Natl Acad Sci U S A (2007) 1.15
Inorganic polyphosphate is a potent activator of the mitochondrial permeability transition pore in cardiac myocytes. J Gen Physiol (2012) 1.10
Polyester modification of the mammalian TRPM8 channel protein: implications for structure and function. Cell Rep (2013) 1.07
Dynamics of matrix-free Ca2+ in cardiac mitochondria: two components of Ca2+ uptake and role of phosphate buffering. J Gen Physiol (2012) 1.01
Role of β-hydroxybutyrate, its polymer poly-β-hydroxybutyrate and inorganic polyphosphate in mammalian health and disease. Front Physiol (2014) 1.01
Insight into the selectivity and gating functions of Streptomyces lividans KcsA. Proc Natl Acad Sci U S A (2007) 0.92
Bcl-xL in neuroprotection and plasticity. Front Physiol (2014) 0.89
Distinct mPTP activation mechanisms in ischaemia-reperfusion: contributions of Ca2+, ROS, pH, and inorganic polyphosphate. Cardiovasc Res (2015) 0.88
Mitochondrial permeability transition pore induction is linked to formation of the complex of ATPase C-subunit, polyhydroxybutyrate and inorganic polyphosphate. Cell Death Discov (2016) 0.88
Mitochondrial ion channels as therapeutic targets. FEBS Lett (2010) 0.85
Role of polyhydroxybutyrate in mitochondrial calcium uptake. Cell Calcium (2013) 0.85
Polyhydroxybutyrate targets mammalian mitochondria and increases permeability of plasmalemmal and mitochondrial membranes. PLoS One (2013) 0.85
Physiological roles of the mitochondrial permeability transition pore. J Bioenerg Biomembr (2016) 0.84
Inorganic polyphosphate--an unusual suspect of the mitochondrial permeability transition mystery. Channels (Austin) (2012) 0.84
Mitochondrial Ca(2+) and regulation of the permeability transition pore. J Bioenerg Biomembr (2016) 0.84
Polystyrene nanoparticle exposure induces ion-selective pores in lipid bilayers. Biochim Biophys Acta (2013) 0.83
Identification of the polyhydroxybutyrate granules in mammalian cultured cells. Chem Biodivers (2012) 0.83
Mitochondrial Ca(2+) uptake pathways. J Bioenerg Biomembr (2016) 0.83
Modulation of mitochondrial ion transport by inorganic polyphosphate - essential role in mitochondrial permeability transition pore. J Bioenerg Biomembr (2016) 0.82
Cell death disguised: The mitochondrial permeability transition pore as the c-subunit of the F(1)F(O) ATP synthase. Pharmacol Res (2015) 0.80
Molecular complementarity between simple, universal molecules and ions limited phenotype space in the precursors of cells. Biol Direct (2014) 0.79
Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels. Mol Brain (2014) 0.79
A mitochondrial membrane exopolyphosphatase is modulated by, and plays a role in, the energy metabolism of hard tick Rhipicephalus (Boophilus) microplus embryos. Int J Mol Sci (2011) 0.76
Other bricks for the correct construction of the mitochondrial permeability transition pore complex. Cell Death Dis (2017) 0.75
The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science (1998) 39.86
Cell death: critical control points. Cell (2004) 22.56
The pathophysiology of mitochondrial cell death. Science (2004) 13.87
The mitochondrial permeability transition pore and its role in cell death. Biochem J (1999) 7.72
Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am J Physiol Cell Physiol (2004) 7.23
The mitochondrial permeability transition. Biochim Biophys Acta (1995) 7.14
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature (2004) 5.85
Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels. Nature (2004) 5.54
A prokaryotic voltage-gated sodium channel. Science (2001) 4.56
JPCalc, a software package for calculating liquid junction potential corrections in patch-clamp, intracellular, epithelial and bilayer measurements and for correcting junction potential measurements. J Neurosci Methods (1994) 4.33
Analysis of Poly-beta-Hydroxybutyrate in Rhizobium japonicum Bacteroids by Ion-Exclusion High-Pressure Liquid Chromatography and UV Detection. Appl Environ Microbiol (1983) 2.93
Ancient invasions: from endosymbionts to organelles. Science (2004) 2.87
The Ca2+-induced membrane transition in mitochondria. II. Nature of the Ca2+ trigger site. Arch Biochem Biophys (1979) 2.44
The adenine nucleotide translocase: a central component of the mitochondrial permeability transition pore and key player in cell death. Curr Med Chem (2003) 2.07
From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state. Biochim Biophys Acta (1998) 2.07
Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury. Mol Cell Biochem (1997) 1.93
A soluble exopolyphosphatase of Saccharomyces cerevisiae. Purification and characterization. J Biol Chem (1994) 1.89
The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A. J Biol Chem (1991) 1.78
Modulation of the mitochondrial megachannel by divalent cations and protons. J Biol Chem (1992) 1.43
Mitochondria in cell death: novel targets for neuroprotection and cardioprotection. Trends Mol Med (2003) 1.37
The mitochondrial megachannel is the permeability transition pore. J Bioenerg Biomembr (1992) 1.35
Historical review: mitochondria and calcium: ups and downs of an unusual relationship. Trends Biochem Sci (2003) 1.31
The inner mitochondrial membrane contains ion-conducting channels similar to those found in bacteria. FEBS Lett (1989) 1.28
Poly-beta-hydroxybutyrate/calcium polyphosphate complexes in eukaryotic membranes. Proc Soc Exp Biol Med (1989) 1.28
Proof for a nonproteinaceous calcium-selective channel in Escherichia coli by total synthesis from (R)-3-hydroxybutanoic acid and inorganic polyphosphate. Proc Natl Acad Sci U S A (1997) 1.22
Poly-3-hydroxybutyrate/polyphosphate complexes form voltage-activated Ca2+ channels in the plasma membranes of Escherichia coli. Biophys J (1995) 1.21
Poly(3-hydroxybutyrate) is associated with specific proteins in the cytoplasm and membranes of Escherichia coli. J Biol Chem (1996) 1.19
Mitochondrial channel activity studied by patch-clamping mitoplasts. J Bioenerg Biomembr (1989) 1.18
A putative prokaryote voltage-gated Ca(2+) channel with only one 6TM motif per subunit. Biochem Biophys Res Commun (2001) 1.17
The mitochondrial permeability transition pore may comprise VDAC molecules. I. Binary structure and voltage dependence of the pore. FEBS Lett (1993) 1.09
Functional evidence for a supramolecular structure for the Streptomyces lividans potassium channel KcsA. Biochem Biophys Res Commun (2004) 1.07
A large Ca2+-dependent channel formed by recombinant ADP/ATP carrier from Neurospora crassa resembles the mitochondrial permeability transition pore. Biochemistry (2002) 1.06
Mitochondrial permeability: dual role for the ADP/ATP translocator? Nature (2004) 1.04
Batten disease and the ATP synthase subunit c turnover pathway: raising antibodies to subunit c. Am J Med Genet (1995) 1.00
Multiple conductance channel activity of wild-type and voltage-dependent anion-selective channel (VDAC)-less yeast mitochondria. Biophys J (1995) 0.99
Modulation of inner mitochondrial membrane channel activity. J Bioenerg Biomembr (1992) 0.98
A 0.1-700 Hz current through a voltage-clamped pore: candidate protein for initiator of neural oscillations. Brain Res (1997) 0.94
Multiple conductance levels in rat heart inner mitochondrial membranes studied by patch clamping. Biochim Biophys Acta (1992) 0.93
The mitochondrial potassium cycle. IUBMB Life (2002) 0.92
Calcium modulation of mitochondrial inner membrane channel activity. Biochem Biophys Res Commun (1991) 0.92
Palmitic and stearic acids bind Ca2+ with high affinity and form nonspecific channels in black-lipid membranes. Possible relation to Ca2+-activated mitochondrial pores. J Bioenerg Biomembr (2001) 0.88
Single-channel currents of the permeability transition pore from the inner mitochondrial membrane of rat liver and of a human hepatoma cell line. Cell Physiol Biochem (2002) 0.84
Oscillating Ca2+-induced channel activity obtained in BLM with a mitochondrial membrane component. J Bioenerg Biomembr (1997) 0.83
Ca(2+)-modulated phosphorylation of a low-molecular-mass polypeptide in rat liver mitochondria: evidence that it is identical with subunit c of F(0)F(1)-ATPase. Biochem Biophys Res Commun (2000) 0.82
Gating kinetics of E. coli poly-3-hydroxybutyrate/polyphosphate channels in planar bilayer membranes. J Membr Biol (1999) 0.80
pH regulates cation selectivity of poly-(R)-3-hydroxybutyrate/polyphosphate channels from E. coli in planar lipid bilayers. Biochemistry (2001) 0.80
Differential effects of temperature on E. coli and synthetic polyhydroxybutyrate/polyphosphate channels. Biochemistry (2002) 0.79
Inorganic polyphosphate modulates TRPM8 channels. PLoS One (2009) 1.64
High sensitivity, quantitative measurements of polyphosphate using a new DAPI-based approach. J Fluoresc (2008) 1.49
Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels. J Biol Chem (2007) 1.48
Targeted polyphosphatase expression alters mitochondrial metabolism and inhibits calcium-dependent cell death. Proc Natl Acad Sci U S A (2007) 1.38
Electrostatic and steric contributions to block of the skeletal muscle sodium channel by mu-conotoxin. J Gen Physiol (2002) 1.33
Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor. Proc Natl Acad Sci U S A (2012) 1.28
The pore, not cytoplasmic domains, underlies inactivation in a prokaryotic sodium channel. Biophys J (2005) 1.25
Osmotic adjustment in chickpea (Cicer arietinum L.) results in no yield benefit under terminal drought. J Exp Bot (2006) 1.13
Synergistic and antagonistic interactions between tetrodotoxin and mu-conotoxin in blocking voltage-gated sodium channels. Channels (Austin) (2009) 1.11
Docking of mu-conotoxin GIIIA in the sodium channel outer vestibule. Channels (Austin) (2007) 1.07
Promiscuous activation of transient receptor potential vanilloid 1 (TRPV1) channels by negatively charged intracellular lipids: the key role of endogenous phosphoinositides in maintaining channel activity. J Biol Chem (2013) 1.06
Modulation of KvAP unitary conductance and gating by 1-alkanols and other surface active agents. Biophys J (2010) 1.04
Enhanced neuronal damage after ischemic insults in mice lacking Kir6.2-containing ATP-sensitive K+ channels. J Neurophysiol (2005) 1.00
Effects of Cav3.2 channel mutations linked to idiopathic generalized epilepsy. Ann Neurol (2005) 0.97
State-dependent inhibition of cystic fibrosis transmembrane conductance regulator chloride channels by a novel peptide toxin. J Biol Chem (2007) 0.93
Novel interactions identified between micro -Conotoxin and the Na+ channel domain I P-loop: implications for toxin-pore binding geometry. Biophys J (2003) 0.92
Insight into the selectivity and gating functions of Streptomyces lividans KcsA. Proc Natl Acad Sci U S A (2007) 0.92
Sodium channel selectivity and conduction: prokaryotes have devised their own molecular strategy. J Gen Physiol (2014) 0.91
Sorting signal of Escherichia coli OmpA is modified by oligo-(R)-3-hydroxybutyrate. Biochim Biophys Acta (2007) 0.90
Multiple, distributed interactions of μ-conotoxin PIIIA associated with broad targeting among voltage-gated sodium channels. Biochemistry (2010) 0.89
A high-conductance mode of a poly-3-hydroxybutyrate/calcium/polyphosphate channel isolated from competent Escherichia coli cells. FEBS Lett (2005) 0.88
Conotoxins as sensors of local pH and electrostatic potential in the outer vestibule of the sodium channel. J Gen Physiol (2003) 0.87
Isolation and characterization of a high affinity peptide inhibitor of ClC-2 chloride channels. J Biol Chem (2009) 0.86
Involvement of nitric oxide synthase in matrix metalloproteinase-9- and/or urokinase plasminogen activator receptor-mediated glioma cell migration. BMC Cancer (2013) 0.85
Role of polyhydroxybutyrate in mitochondrial calcium uptake. Cell Calcium (2013) 0.85
Involvement of hippocampal CA3 K(ATP) channels in contextual memory. Neuropharmacology (2008) 0.84
Identification of the polyhydroxybutyrate granules in mammalian cultured cells. Chem Biodivers (2012) 0.83
RTX toxin plays a key role in Kingella kingae virulence in an infant rat model. Infect Immun (2014) 0.82
Interplay between calmodulin and phosphatidylinositol 4,5-bisphosphate in Ca2+-induced inactivation of transient receptor potential vanilloid 6 channels. J Biol Chem (2013) 0.82
Resolving the native conformation of Escherichia coli OmpA. FEBS J (2010) 0.80
Targeting DUSPs in glioblastomas - wielding a double-edged sword? Cell Biol Int (2013) 0.80
Importance of oligo-R-3-hydroxybutyrates to S. lividans KcsA channel structure and function. Mol Biosyst (2010) 0.80
Cardioselectivity of the sulphonylurea HMR 1098: studies on native and recombinant cardiac and pancreatic K(ATP) channels. Br J Pharmacol (2002) 0.80
Molecular complementarity between simple, universal molecules and ions limited phenotype space in the precursors of cells. Biol Direct (2014) 0.79
Inhibition of a cardiac sarcoplasmic reticulum chloride channel by tamoxifen. Pflugers Arch (2008) 0.79
Role of polyphosphate in regulation of the Streptomyces lividans KcsA channel. Biochim Biophys Acta (2009) 0.79
Poly-3-hydroxybutyrate synthase from the periplasm of Escherichia coli. Biochem Biophys Res Commun (2008) 0.79
Trans-channel interactions in batrachotoxin-modified rat skeletal muscle sodium channels: kinetic analysis of mutual inhibition between mu-conotoxin GIIIA derivatives and amine blockers. Biophys J (2008) 0.78
Hypothesis: poly-(R)-3-hydroxybutyrate is a major factor in intraocular pressure. Med Hypotheses (2009) 0.78
Block of Kv1.7 potassium currents increases glucose-stimulated insulin secretion. EMBO Mol Med (2012) 0.78
A method for identifying viable and damaged neurons in adult mouse brain slices. Acta Histochem (2009) 0.78
Open-state stabilization in Kv channels: voltage-sensor relaxation and pore propping by a bound ion. J Gen Physiol (2012) 0.76
Poly-(R)-3-hydroxybutyrates (PHB) are Atherogenic Components of Lipoprotein Lp(a). Med Hypotheses (2015) 0.75
Polyhydroxybutyrate-enhanced transformation of log-phase Escherichia coli. Biotechniques (2004) 0.75