PubRank

Vincent J Hearing

Author PubWeight™ 108.05‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Human skin pigmentation: melanocytes modulate skin color in response to stress. FASEB J 2007 2.62
2 The protective role of melanin against UV damage in human skin. Photochem Photobiol 2008 2.45
3 The regulation of skin pigmentation. J Biol Chem 2007 2.02
4 Physiological factors that regulate skin pigmentation. Biofactors 2009 1.93
5 UV-induced DNA damage and melanin content in human skin differing in racial/ethnic origin. FASEB J 2003 1.88
6 The effects of dickkopf 1 on gene expression and Wnt signaling by melanocytes: mechanisms underlying its suppression of melanocyte function and proliferation. J Invest Dermatol 2006 1.72
7 Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. J Proteome Res 2006 1.63
8 Mechanisms of skin tanning in different racial/ethnic groups in response to ultraviolet radiation. J Invest Dermatol 2005 1.60
9 Mesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation. J Cell Biol 2004 1.56
10 Human skin responses to UV radiation: pigment in the upper epidermis protects against DNA damage in the lower epidermis and facilitates apoptosis. FASEB J 2006 1.55
11 The repeat domain of the melanosomal matrix protein PMEL17/GP100 is required for the formation of organellar fibers. J Biol Chem 2006 1.46
12 Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the underwhite (uw) mutation. A model for oculocutaneous albinism (OCA) type 4. J Cell Sci 2003 1.45
13 Diacylglycerol kinase regulates tyrosinase expression and function in human melanocytes. J Invest Dermatol 2012 1.43
14 Regulation of human skin pigmentation and responses to ultraviolet radiation. Pigment Cell Res 2007 1.41
15 Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma. Pigment Cell Melanoma Res 2009 1.38
16 Approaches to identify inhibitors of melanin biosynthesis via the quality control of tyrosinase. J Invest Dermatol 2007 1.37
17 MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes. J Biol Chem 2005 1.36
18 SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentation. Proc Natl Acad Sci U S A 2007 1.32
19 Proteomic analysis of early melanosomes: identification of novel melanosomal proteins. J Proteome Res 2003 1.31
20 Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin. Proc Natl Acad Sci U S A 2004 1.31
21 Dickkopf 1 (DKK1) regulates skin pigmentation and thickness by affecting Wnt/beta-catenin signaling in keratinocytes. FASEB J 2007 1.29
22 Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid. J Clin Invest 2009 1.28
23 Regulation of tyrosinase processing and trafficking by organellar pH and by proteasome activity. J Biol Chem 2003 1.27
24 Regulation of human skin pigmentation in situ by repetitive UV exposure: molecular characterization of responses to UVA and/or UVB. J Invest Dermatol 2010 1.27
25 The etiology of oculocutaneous albinism (OCA) type II: the pink protein modulates the processing and transport of tyrosinase. Pigment Cell Res 2002 1.23
26 Sorting of Pmel17 to melanosomes through the plasma membrane by AP1 and AP2: evidence for the polarized nature of melanocytes. J Cell Sci 2006 1.20
27 Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation. J Cell Sci 2002 1.19
28 UVA tanning is involved in the increased incidence of skin cancers in fair-skinned young women. Pigment Cell Melanoma Res 2009 1.19
29 MC1R and the response of melanocytes to ultraviolet radiation. Mutat Res 2005 1.18
30 Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas. Proc Natl Acad Sci U S A 2006 1.18
31 Stimulation of melanoblast pigmentation by 8-methoxypsoralen:the involvement of microphthalmia-associated transcription factor, the protein kinase a signal pathway, and proteasome-mediated degradation. J Invest Dermatol 2002 1.17
32 Update on the regulation of mammalian melanocyte function and skin pigmentation. Expert Rev Dermatol 2011 1.15
33 Principal expression of two mRNA isoforms (ABCB 5alpha and ABCB 5beta ) of the ATP-binding cassette transporter gene ABCB 5 in melanoma cells and melanocytes. Pigment Cell Res 2005 1.12
34 Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein. FASEB J 2010 1.12
35 Cyclobutane pyrimidine dimer formation and p53 production in human skin after repeated UV irradiation. Exp Dermatol 2008 1.08
36 Regulation of eumelanin/pheomelanin synthesis and visible pigmentation in melanocytes by ligands of the melanocortin 1 receptor. Pigment Cell Melanoma Res 2008 1.07
37 Tyrosinase: a developmentally specific major determinant of peripheral dopamine. FASEB J 2003 1.06
38 Comparative Bioinformatics Analyses and Profiling of Lysosome-Related Organelle Proteomes. Int J Mass Spectrom 2007 1.04
39 Aberrant trafficking of human melanocortin 1 receptor variants associated with red hair and skin cancer: Steady-state retention of mutant forms in the proximal golgi. J Cell Physiol 2009 1.03
40 Sialylated core 1 O-glycans influence the sorting of Pmel17/gp100 and determine its capacity to form fibrils. J Biol Chem 2007 1.03
41 Fatty acids regulate pigmentation via proteasomal degradation of tyrosinase: a new aspect of ubiquitin-proteasome function. J Biol Chem 2004 1.01
42 The fibroblast-derived paracrine factor neuregulin-1 has a novel role in regulating the constitutive color and melanocyte function in human skin. J Cell Sci 2010 1.00
43 Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1r. Proc Natl Acad Sci U S A 2009 1.00
44 Epitope mapping of the melanosomal matrix protein gp100 (PMEL17): rapid processing in the endoplasmic reticulum and glycosylation in the early Golgi compartment. J Biol Chem 2004 1.00
45 The inhibitory effect of androgen and sex-hormone-binding globulin on the intracellular cAMP level and tyrosinase activity of normal human melanocytes. Pigment Cell Res 2003 0.98
46 Evidence for the ectopic synthesis of melanin in human adipose tissue. FASEB J 2008 0.98
47 Melanocytes and their diseases. Cold Spring Harb Perspect Med 2014 0.97
48 Pigmentation effects of solar-simulated radiation as compared with UVA and UVB radiation. Pigment Cell Melanoma Res 2008 0.97
49 Direct interaction of tyrosinase with Tyrp1 to form heterodimeric complexes in vivo. J Cell Sci 2007 0.97
50 The secreted form of a melanocyte membrane-bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding. FASEB J 2009 0.97
51 Mesenchymal-epithelial interactions in the skin: aiming for site-specific tissue regeneration. J Dermatol Sci 2005 0.97
52 The deceptive nature of UVA tanning versus the modest protective effects of UVB tanning on human skin. Pigment Cell Melanoma Res 2010 0.97
53 Involvement of dynein and spectrin with early melanosome transport and melanosomal protein trafficking. J Invest Dermatol 2007 0.96
54 Melanin mediated apoptosis of epidermal cells damaged by ultraviolet radiation: factors influencing the incidence of skin cancer. Arch Dermatol Res 2008 0.95
55 Intracellular composition of fatty acid affects the processing and function of tyrosinase through the ubiquitin-proteasome pathway. Biochem J 2006 0.94
56 The Seiji memorial lecture: the melanosome: an ideal model to study cellular differentiation. Pigment Cell Res 2003 0.93
57 Regulation of melanocortin 1 receptor expression at the mRNA and protein levels by its natural agonist and antagonist. FASEB J 2003 0.93
58 AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma. Proc Natl Acad Sci U S A 2011 0.92
59 Forskolin protects keratinocytes from UVB-induced apoptosis and increases DNA repair independent of its effects on melanogenesis. J Invest Dermatol 2008 0.91
60 Down-regulation of melanogenesis by phospholipase D2 through ubiquitin proteasome-mediated degradation of tyrosinase. J Biol Chem 2004 0.90
61 NUAK2: an emerging acral melanoma oncogene. Oncotarget 2011 0.90
62 A melanocyte-keratinocyte coculture model to assess regulators of pigmentation in vitro. Anal Biochem 2002 0.90
63 Reconstituted 3-dimensional human skin of various ethnic origins as an in vitro model for studies of pigmentation. Anal Biochem 2003 0.89
64 In vitro migration of melanoblasts requires matrix metalloproteinase-2: implications to vitiligo therapy by photochemotherapy. Pigment Cell Res 2002 0.88
65 Modifying skin pigmentation - approaches through intrinsic biochemistry and exogenous agents. Drug Discov Today Dis Mech 2008 0.88
66 Long-lasting molecular changes in human skin after repetitive in situ UV irradiation. J Invest Dermatol 2008 0.87
67 Mutations in dopachrome tautomerase (Dct) affect eumelanin/pheomelanin synthesis, but do not affect intracellular trafficking of the mutant protein. Biochem J 2005 0.87
68 Influence of alpha-melanocyte-stimulating hormone and ultraviolet radiation on the transfer of melanosomes to keratinocytes. FASEB J 2001 0.87
69 Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease. J Neurochem 2005 0.87
70 Different approaches for assaying melanosome transfer. Pigment Cell Res 2005 0.86
71 Immunohistochemistry and in situ hybridization in the study of human skin melanocytes. Exp Dermatol 2007 0.86
72 Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clin Cosmet Investig Dermatol 2010 0.86
73 Influence of melanosome dynamics on melanoma drug sensitivity. J Natl Cancer Inst 2009 0.86
74 Long-lasting pigmentation of human skin, a new look at an overlooked response to UV. Pigment Cell Melanoma Res 2009 0.86
75 Regulation of constitutive and UVR-induced skin pigmentation by melanocortin 1 receptor isoforms. FASEB J 2006 0.85
76 Regulation of skin pigmentation and thickness by Dickkopf 1 (DKK1). J Investig Dermatol Symp Proc 2009 0.85
77 Role of the ubiquitin proteasome system in regulating skin pigmentation. Int J Mol Sci 2009 0.85
78 Regulating melanosome transfer: who's driving the bus? Pigment Cell Res 2007 0.85
79 Epidermal gene expression and ethnic pigmentation variations among individuals of Asian, European and African ancestry. Exp Dermatol 2014 0.84
80 UV exposure modulates hemidesmosome plasticity, contributing to long-term pigmentation in human skin. J Pathol 2015 0.84
81 Regulatory elements of the melanocortin 1 receptor. Peptides 2005 0.84
82 Pmel17: controversial indeed but critical to melanocyte function. Pigment Cell Res 2006 0.84
83 Photobiologic role of melanin distribution in the epidermis. J Photochem Photobiol B 2006 0.82
84 Photobiological implications of melanin photoprotection after UVB-induced tanning of human skin but not UVA-induced tanning. Pigment Cell Melanoma Res 2015 0.81
85 The effects of topically applied glycolic acid and salicylic acid on ultraviolet radiation-induced erythema, DNA damage and sunburn cell formation in human skin. J Dermatol Sci 2009 0.81
86 Short- and long-term effects of UV radiation on the pigmentation of human skin. J Investig Dermatol Symp Proc 2009 0.81
87 Characterization of the bioactive motif of neuregulin-1, a fibroblast-derived paracrine factor that regulates the constitutive color and the function of melanocytes in human skin. Pigment Cell Melanoma Res 2012 0.79
88 Standardization of in vitro macrophotography for assessment of cutaneous responses. Photochem Photobiol 2009 0.79
89 The expanding role and presence of neuromelanins in the human brain - why gray matter is gray. Pigment Cell Melanoma Res 2008 0.78
90 Antibody αPEP13h reacts with lymphangioleiomyomatosis cells in lung nodules. Chest 2015 0.78
91 Immortalization of mouse melanocytes carrying mutations in various pigmentation genes. Anal Biochem 2004 0.78
92 NADPH:quinone oxidoreductase-1 as a new regulatory enzyme that increases melanin synthesis. J Invest Dermatol 2010 0.78
93 Synergistic effect of interleukin-2 and a vaccine of irradiated melanoma cells transfected to secrete staphylococcal enterotoxin A. Clin Exp Metastasis 2002 0.77
94 Essential role of the molecular chaperone gp96 in regulating melanogenesis. Pigment Cell Melanoma Res 2013 0.77
95 Isolation of melanosomes. Curr Protoc Cell Biol 2005 0.76
96 Co-culture of mouse epidermal cells for studies of pigmentation. Pigment Cell Res 2003 0.76
97 Effects of cosmetic formulations containing hydroxyacids on sun-exposed skin: current applications and future developments. Dermatol Res Pract 2012 0.75
98 Evidence for a new paradigm for ultraviolet exposure: a universal schedule that is skin phototype independent. Photodermatol Photoimmunol Photomed 2012 0.75
99 A novel approach to enhance antibody sensitivity and specificity by peptide cross-linking. Anal Biochem 2008 0.75
100 Non-invasive diffuse reflectance measurements of cutaneous melanin content can predict human sensitivity to ultraviolet radiation. Exp Dermatol 2013 0.75
101 The Roles of ADAMs Family Proteinases in Skin Diseases. Enzyme Res 2011 0.75
102 UV increases the nuclear localization of apurinic/apyrimidinic endonuclease/redox effector factor-1 in human skin. J Invest Dermatol 2006 0.75