Published in Ann Otol Rhinol Laryngol Suppl on January 01, 2005
Moraxella catarrhalis strain O35E expresses two filamentous hemagglutinin-like proteins that mediate adherence to human epithelial cells. Infect Immun (2007) 1.07
Construction of a mutant and characterization of the role of the vaccine antigen P6 in outer membrane integrity of nontypeable Haemophilus influenzae. Infect Immun (2006) 1.02
The Moraxella catarrhalis autotransporter McaP is a conserved surface protein that mediates adherence to human epithelial cells through its N-terminal passenger domain. Infect Immun (2006) 0.97
Vaccines for Nontypeable Haemophilus influenzae: the Future Is Now. Clin Vaccine Immunol (2015) 0.94
Mouse models for human otitis media. Brain Res (2009) 0.92
Association of IS1016 with the hia adhesin gene and biotypes V and I in invasive nontypeable Haemophilus influenzae. Infect Immun (2008) 0.88
Hag mediates adherence of Moraxella catarrhalis to ciliated human airway cells. Infect Immun (2009) 0.86
Characterization of a novel porin protein from Moraxella catarrhalis and identification of an immunodominant surface loop. J Bacteriol (2005) 0.86
Differential uptake and processing of a Haemophilus influenzae P5-derived immunogen by chinchilla dendritic cells. Infect Immun (2007) 0.83
Mouse models for the study of mucosal vaccination against otitis media. Vaccine (2008) 0.83
Moraxella catarrhalis uses a twin-arginine translocation system to secrete the β-lactamase BRO-2. BMC Microbiol (2013) 0.78
Use of the Chinchilla model to evaluate the vaccinogenic potential of the Moraxella catarrhalis filamentous hemagglutinin-like proteins MhaB1 and MhaB2. PLoS One (2013) 0.76
New strains of bacteria and exacerbations of chronic obstructive pulmonary disease. N Engl J Med (2002) 7.87
Infection in the pathogenesis and course of chronic obstructive pulmonary disease. N Engl J Med (2008) 4.33
Effectiveness of inactivated influenza vaccine in children aged 9 months to 3 years: an observational cohort study. Lancet Infect Dis (2010) 3.87
Viral upper respiratory tract infection and otitis media complication in young children. Clin Infect Dis (2008) 3.75
Severe human lower respiratory tract illness caused by respiratory syncytial virus and influenza virus is characterized by the absence of pulmonary cytotoxic lymphocyte responses. J Infect Dis (2007) 3.62
Quantification of lean bodyweight. Clin Pharmacokinet (2005) 3.59
Post-PCV7 changes in colonizing pneumococcal serotypes in 16 Massachusetts communities, 2001 and 2004. Pediatrics (2005) 3.42
Continued impact of pneumococcal conjugate vaccine on carriage in young children. Pediatrics (2009) 3.32
Severe community-acquired pneumonia due to Staphylococcus aureus, 2003-04 influenza season. Emerg Infect Dis (2006) 2.79
Differential effects of pneumococcal vaccines against serotypes 6A and 6C. J Infect Dis (2008) 2.70
Population genomics of post-vaccine changes in pneumococcal epidemiology. Nat Genet (2013) 2.63
Airway bacterial concentrations and exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2007) 2.59
Increase in the prevalence of the newly discovered pneumococcal serotype 6C in the nasopharynx after introduction of pneumococcal conjugate vaccine. J Infect Dis (2009) 2.36
Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20. J Bacteriol (2005) 2.31
HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response. J Immunol (2005) 2.24
Microbial interactions during upper respiratory tract infections. Emerg Infect Dis (2008) 2.18
Biofilms formed by nontypeable Haemophilus influenzae in vivo contain both double-stranded DNA and type IV pilin protein. J Bacteriol (2007) 2.14
Nontypeable Haemophilus influenzae as a pathogen in children. Pediatr Infect Dis J (2009) 2.12
Microbiology of acute otitis media in children with tympanostomy tubes: prevalences of bacteria and viruses. Clin Infect Dis (2006) 2.06
Relationships of nontypeable Haemophilus influenzae strains to hemolytic and nonhemolytic Haemophilus haemolyticus strains. J Clin Microbiol (2007) 2.04
Diversity and antibiotic resistance among nonvaccine serotypes of Streptococcus pneumoniae carriage isolates in the post-heptavalent conjugate vaccine era. J Infect Dis (2006) 1.99
Immunogenicity, immunologic memory, and safety following measles revaccination in HIV-infected children receiving highly active antiretroviral therapy. J Infect Dis (2012) 1.98
Effect of the 2009 influenza A/H1N1 pandemic on viral respiratory infections in the first year of life. Pediatr Infect Dis J (2012) 1.97
Strain-specific immune response to Haemophilus influenzae in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2003) 1.93
The Haemophilus influenzae HMW1 adhesin is glycosylated in a process that requires HMW1C and phosphoglucomutase, an enzyme involved in lipooligosaccharide biosynthesis. Mol Microbiol (2003) 1.84
Differential type I interferon induction by respiratory syncytial virus and influenza a virus in vivo. J Virol (2007) 1.77
Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media. Proc Natl Acad Sci U S A (2003) 1.75
Evidence that pneumococcal serotype replacement in Massachusetts following conjugate vaccination is now complete. Epidemics (2010) 1.72
Phosphorylcholine decreases early inflammation and promotes the establishment of stable biofilm communities of nontypeable Haemophilus influenzae strain 86-028NP in a chinchilla model of otitis media. Infect Immun (2006) 1.71
Initiation of NALT organogenesis is independent of the IL-7R, LTbetaR, and NIK signaling pathways but requires the Id2 gene and CD3(-)CD4(+)CD45(+) cells. Immunity (2002) 1.70
Otitis media and its consequences: beyond the earache. Lancet Infect Dis (2010) 1.68
Changing serotypes causing childhood invasive pneumococcal disease: Massachusetts, 2001-2007. Pediatr Infect Dis J (2010) 1.67
Role of sialic acid and complex carbohydrate biosynthesis in biofilm formation by nontypeable Haemophilus influenzae in the chinchilla middle ear. Infect Immun (2005) 1.65
Nontypeable Haemophilus influenzae gene expression induced in vivo in a chinchilla model of otitis media. Infect Immun (2003) 1.63
Recurrent variable region gene usage and somatic mutation in the human antibody response to the capsular polysaccharide of Streptococcus pneumoniae type 23F. Infect Immun (2002) 1.62
Bacteria challenge in smoke-exposed mice exacerbates inflammation and skews the inflammatory profile. Am J Respir Crit Care Med (2009) 1.61
The PilA protein of non-typeable Haemophilus influenzae plays a role in biofilm formation, adherence to epithelial cells and colonization of the mammalian upper respiratory tract. Mol Microbiol (2007) 1.53
Early oseltamivir treatment of influenza in children 1-3 years of age: a randomized controlled trial. Clin Infect Dis (2010) 1.51
A case of cochlear nerve deficiency without profound sensorineural hearing loss. Otol Neurotol (2011) 1.50
Antibiotic treatment of acute otorrhea through tympanostomy tube: randomized double-blind placebo-controlled study with daily follow-up. Pediatrics (2003) 1.47
Ethical concerns about federal approval of risky pediatric studies. Pediatrics (2004) 1.47
Incidence of acute otitis media and sinusitis complicating upper respiratory tract infection: the effect of age. Pediatrics (2007) 1.43
Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKbeta-IkappaBalpha-NF-kappaB signaling pathways. Biochem Biophys Res Commun (2004) 1.42
Population pharmacokinetics of enoxaparin during the antenatal period. Circulation (2013) 1.41
Routine plasma anti-Xa monitoring is required for low-molecular-weight heparins. Clin Pharmacokinet (2010) 1.41
Nasal colonization with Streptococcus pneumoniae includes subpopulations of surface and invasive pneumococci. Infect Immun (2005) 1.41
Pneumococcal carriage and antibiotic resistance in young children before 13-valent conjugate vaccine. Pediatr Infect Dis J (2012) 1.41
Cost of routine immunization of young children against rotavirus infection with Rotarix versus RotaTeq. Vaccine (2009) 1.40
Severity of invasive pneumococcal disease in children caused by susceptible and nonsusceptible isolates. Pediatr Infect Dis J (2014) 1.40
Accuracy of clinical diagnosis of influenza in outpatient children. Clin Infect Dis (2005) 1.39
Neuropsychological functioning and viral load in stable antiretroviral therapy-experienced HIV-infected children. Pediatrics (2005) 1.39
The Haemophilus influenzae Hia autotransporter harbours two adhesive pockets that reside in the passenger domain and recognize the same host cell receptor. Mol Microbiol (2002) 1.39
Haemophilus influenzae infections in the H. influenzae type b conjugate vaccine era. J Clin Microbiol (2011) 1.38
Inflammatory profile of new bacterial strain exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2007) 1.38
Antibiotic-resistant Streptococcus pneumoniae in the heptavalent pneumococcal conjugate vaccine era: predictors of carriage in a multicommunity sample. Pediatrics (2003) 1.37
Microbial interactions in the respiratory tract. Pediatr Infect Dis J (2009) 1.37
A mutation in the sap operon attenuates survival of nontypeable Haemophilus influenzae in a chinchilla model of otitis media. Infect Immun (2005) 1.37
Evolutionary and functional relationships among the nontypeable Haemophilus influenzae HMW family of adhesins. J Bacteriol (2004) 1.36
Cost-effectiveness of influenza vaccination of healthy children. Vaccine (2006) 1.36
The Haemophilus influenzae Hia autotransporter contains an unusually short trimeric translocator domain. J Biol Chem (2004) 1.35
Haemophilus influenzae from patients with chronic obstructive pulmonary disease exacerbation induce more inflammation than colonizers. Am J Respir Crit Care Med (2005) 1.34
Food commensal microbes as a potentially important avenue in transmitting antibiotic resistance genes. FEMS Microbiol Lett (2006) 1.34
Immunogenicity, safety, and predictors of response after a pneumococcal conjugate and pneumococcal polysaccharide vaccine series in human immunodeficiency virus-infected children receiving highly active antiretroviral therapy. Pediatr Infect Dis J (2006) 1.32
Association of clinical signs and symptoms with bacterial findings in acute otitis media. Clin Infect Dis (2003) 1.29
Carried pneumococci in Massachusetts children: the contribution of clonal expansion and serotype switching. Pediatr Infect Dis J (2011) 1.28
The multifunctional host defense peptide SPLUNC1 is critical for homeostasis of the mammalian upper airway. PLoS One (2010) 1.26
Pharmacokinetics and pharmacodynamics of monoclonal antibodies: concepts and lessons for drug development. BioDrugs (2010) 1.26
Role of complement in defense of the middle ear revealed by restoring the virulence of nontypeable Haemophilus influenzae siaB mutants. Infect Immun (2006) 1.25
Somatic hypermutation and diverse immunoglobulin gene usage in the human antibody response to the capsular polysaccharide of Streptococcus pneumoniae Type 6B. Infect Immun (2004) 1.24
Persistence of adenovirus nucleic acids in nasopharyngeal secretions: a diagnostic conundrum. Pediatr Infect Dis J (2010) 1.24
Public health and economic impact of the 13-valent pneumococcal conjugate vaccine (PCV13) in the United States. Vaccine (2010) 1.23
Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens. Proc Natl Acad Sci U S A (2013) 1.23
Nontypeable Haemophilus influenzae adheres to intercellular adhesion molecule 1 (ICAM-1) on respiratory epithelial cells and upregulates ICAM-1 expression. Infect Immun (2006) 1.22
Multinational study of pneumococcal serotypes causing acute otitis media in children. Pediatr Infect Dis J (2002) 1.22
A dynamic model of pneumococcal infection in the United States: implications for prevention through vaccination. Vaccine (2010) 1.22
Impact of saliva collection methods on sIgA and cortisol assays and acceptability to participants. J Immunol Methods (2005) 1.22
The relationship between drug clearance and body size: systematic review and meta-analysis of the literature published from 2000 to 2007. Clin Pharmacokinet (2012) 1.22
Contribution of Moraxella catarrhalis type IV pili to nasopharyngeal colonization and biofilm formation. Infect Immun (2007) 1.21
Experimental acute otitis media due to nontypeable Haemophilus influenzae: comparison of high and low azithromycin doses with placebo. Antimicrob Agents Chemother (2002) 1.20
Reduced severity of middle ear infection caused by nontypeable Haemophilus influenzae lacking the hemoglobin/hemoglobin-haptoglobin binding proteins (Hgp) in a chinchilla model of otitis media. Microb Pathog (2004) 1.19
Recent advances in otitis media. 1. Definitions, terminology, and classification of otitis media. Ann Otol Rhinol Laryngol Suppl (2002) 1.18
Analysis of population pharmacokinetic data using NONMEM and WinBUGS. J Biopharm Stat (2005) 1.18
The Haemophilus influenzae Hap autotransporter mediates microcolony formation and adherence to epithelial cells and extracellular matrix via binding regions in the C-terminal end of the passenger domain. Cell Microbiol (2003) 1.17
Breast-feeding is associated with a reduced frequency of acute otitis media and high serum antibody levels against NTHi and outer membrane protein vaccine antigen candidate P6. Pediatr Res (2009) 1.17
The non-typeable Haemophilus influenzae Sap transporter provides a mechanism of antimicrobial peptide resistance and SapD-dependent potassium acquisition. Mol Microbiol (2006) 1.17
Differential adaptation of microbial pathogens to airways of patients with cystic fibrosis and chronic obstructive pulmonary disease. FEMS Microbiol Rev (2011) 1.16
Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice. J Clin Invest (2012) 1.16
Moraxella catarrhalis bacterium without endotoxin, a potential vaccine candidate. Infect Immun (2005) 1.15
Outer membrane protein P6 of nontypeable Haemophilus influenzae is a potent and selective inducer of human macrophage proinflammatory cytokines. Infect Immun (2005) 1.14
The Global Meningococcal Initiative: recommendations for reducing the global burden of meningococcal disease. Vaccine (2011) 1.14
In vivo effects of bifidobacteria and lactoferrin on gut endotoxin concentration and mucosal immunity in Balb/c mice. Dig Dis Sci (2004) 1.13
The OxyR regulon in nontypeable Haemophilus influenzae. J Bacteriol (2006) 1.13
Partial analysis of the genomes of two nontypeable Haemophilus influenzae otitis media isolates. Infect Immun (2004) 1.13
Viral etiology of common cold in children, Finland. Emerg Infect Dis (2009) 1.13
Re-emergence of the type 1 pilus among Streptococcus pneumoniae isolates in Massachusetts, USA. Vaccine (2010) 1.12
Molecular basis of increased serum resistance among pulmonary isolates of non-typeable Haemophilus influenzae. PLoS Pathog (2011) 1.12