Published in Chromosome Res on January 01, 2004
Neocentromeres: new insights into centromere structure, disease development, and karyotype evolution. Am J Hum Genet (2008) 2.88
Centromere identity is specified by a single centromeric nucleosome in budding yeast. Proc Natl Acad Sci U S A (2007) 2.58
CENP-A exceeds microtubule attachment sites in centromere clusters of both budding and fission yeast. J Cell Biol (2011) 2.04
Transgenerational propagation and quantitative maintenance of paternal centromeres depends on Cid/Cenp-A presence in Drosophila sperm. PLoS Biol (2012) 1.86
Loading of Arabidopsis centromeric histone CENH3 occurs mainly during G2 and requires the presence of the histone fold domain. Plant Cell (2006) 1.72
Neocentromeres form efficiently at multiple possible loci in Candida albicans. PLoS Genet (2009) 1.55
Genomic and genetic characterization of rice Cen3 reveals extensive transcription and evolutionary implications of a complex centromere. Plant Cell (2006) 1.27
The quantitative architecture of centromeric chromatin. Elife (2014) 1.26
Three-dimensional localization of CENP-A suggests a complex higher order structure of centromeric chromatin. J Cell Biol (2008) 1.20
Intergenic locations of rice centromeric chromatin. PLoS Biol (2008) 1.13
Increased missegregation and chromosome loss with decreasing chromosome size in vertebrate cells. Chromosoma (2005) 1.10
Genomic size of CENP-A domain is proportional to total alpha satellite array size at human centromeres and expands in cancer cells. Chromosome Res (2011) 1.10
A minimal CENP-A core is required for nucleation and maintenance of a functional human centromere. EMBO J (2007) 1.08
Neocentromeres and epigenetically inherited features of centromeres. Chromosome Res (2012) 1.07
Identification of a maize neocentromere in an oat-maize addition line. Cytogenet Genome Res (2009) 1.03
The evolutionary life cycle of the resilient centromere. Chromosoma (2012) 0.98
Maize centromeres expand and adopt a uniform size in the genetic background of oat. Genome Res (2013) 0.97
Centromere inactivation and epigenetic modifications of a plant chromosome with three functional centromeres. Chromosoma (2010) 0.95
Total centromere size and genome size are strongly correlated in ten grass species. Chromosome Res (2012) 0.87
Stable complex formation of CENP-B with the CENP-A nucleosome. Nucleic Acids Res (2015) 0.81
The mouse A/HeJ Y chromosome: another good Y gone bad. Chromosome Res (2008) 0.79
Putative CENP-B paralogues are not present at mammalian centromeres. Chromosoma (2011) 0.79
Lessons learned from counting molecules: how to lure CENP-A into the kinetochore. Open Biol (2014) 0.76
Chromosome Y centromere array deletion leads to impaired centromere function. PLoS One (2014) 0.75
Conserved organization of centromeric chromatin in flies and humans. Dev Cell (2002) 5.06
Genomic and genetic definition of a functional human centromere. Science (2001) 4.28
The centromere-kinetochore complex: a repeat subunit model. J Cell Biol (1991) 4.04
Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere. J Cell Biol (1994) 3.99
A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles and with histones. J Cell Biol (1987) 3.92
Sequencing of a rice centromere uncovers active genes. Nat Genet (2004) 3.66
Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres. Curr Biol (1997) 3.62
Assembly of CENP-A into centromeric chromatin requires a cooperative array of nucleosomal DNA contact sites. J Cell Biol (1997) 3.62
Human centromere protein A (CENP-A) can replace histone H3 in nucleosome reconstitution in vitro. Proc Natl Acad Sci U S A (2000) 2.91
Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A. J Cell Sci (2001) 2.82
Visualization of centromere proteins CENP-B and CENP-C on a stable dicentric chromosome in cytological spreads. Chromosoma (1989) 2.71
Neocentromeres: role in human disease, evolution, and centromere study. Am J Hum Genet (2002) 2.30
Structure of the supernumerary ring and giant rod chromosomes in adipose tissue tumors. Genes Chromosomes Cancer (1999) 2.29
Centromere emergence in evolution. Genome Res (2001) 2.18
CENP-A, -B, and -C chromatin complex that contains the I-type alpha-satellite array constitutes the prekinetochore in HeLa cells. Mol Cell Biol (2002) 2.11
A functional marker centromere with no detectable alpha-satellite, satellite III, or CENP-B protein: activation of a latent centromere? Am J Hum Genet (1993) 2.03
Localization of DNA sequences required for human centromere function through an analysis of rearranged Y chromosomes. Nat Genet (1993) 1.92
CENP-B box is required for de novo centromere chromatin assembly on human alphoid DNA. J Cell Biol (2002) 1.90
The activation of a neocentromere in Drosophila requires proximity to an endogenous centromere. Genetics (2001) 1.90
Functional complementation of human centromere protein A (CENP-A) by Cse4p from Saccharomyces cerevisiae. Mol Cell Biol (2004) 1.85
A novel chromatin immunoprecipitation and array (CIA) analysis identifies a 460-kb CENP-A-binding neocentromere DNA. Genome Res (2001) 1.75
Centromere protein B null mice are mitotically and meiotically normal but have lower body and testis weights. J Cell Biol (1998) 1.68
A 330 kb CENP-A binding domain and altered replication timing at a human neocentromere. EMBO J (2001) 1.65
Human centromeres and neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins. Hum Mol Genet (2000) 1.63
Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array. EMBO J (2002) 1.58
Genomic microarray analysis reveals distinct locations for the CENP-A binding domains in three human chromosome 13q32 neocentromeres. Hum Mol Genet (2003) 1.45
Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns. Hum Mol Genet (2003) 1.25
Compound kinetochores of the Indian muntjac. Evolution by linear fusion of unit kinetochores. Chromosoma (1984) 1.18
CENP-B interacts with CENP-C domains containing Mif2 regions responsible for centromere localization. J Biol Chem (2003) 1.17
Mapping of a human centromere onto the DNA by topoisomerase II cleavage. EMBO Rep (2000) 1.15
Relevance of kinetochore size and microtubule-binding capacity for stable chromosome attachment during mitosis in PtK1 cells. Chromosome Res (1998) 1.13
Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation. Proc Natl Acad Sci U S A (2001) 1.06
Centric fission--simple and complex mechanisms. Chromosome Res (2004) 0.98
Trisomy 20p resulting from inverted duplication and neocentromere formation. Am J Med Genet (1999) 0.98
Partially functional Cenpa-GFP fusion protein causes increased chromosome missegregation and apoptosis during mouse embryogenesis. Chromosome Res (2003) 0.98
Y chromosome aneuploidy, micronuclei, kinetochores and aging in men. Chromosoma (1995) 0.95
Indirect immunofluorescence of inactive centromeres as indicator of centromeric function. Hum Genet (1986) 0.94
Alphoidless centromere of a familial unstable inverted Y chromosome. Ann Genet (1996) 0.93
Kinetochore size variation in mammalian chromosomes: an image analysis study with evolutionary implications. J Cell Sci (1989) 0.93
Centromere/kinetochore localization of human centromere protein A (CENP-A) exogenously expressed as a fusion to green fluorescent protein. Cell Struct Funct (2000) 0.89
Flow cytometry measurements of human chromosome kinetochore labeling. Cytometry (1989) 0.81
Size variation in kinetochores of human chromosomes. Hum Genet (1987) 0.80
Immunofluorescent labeling of centromeres for flow cytometric analysis. Cytometry (1992) 0.77
Pyogenic bacterial infections in humans with MyD88 deficiency. Science (2008) 4.92
ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells. Genome Res (2010) 3.46
Neocentromeres: new insights into centromere structure, disease development, and karyotype evolution. Am J Hum Genet (2008) 2.88
Pseudosarcomatous myofibroblastic proliferations of the bladder: a clinicopathologic study of 42 cases. Am J Surg Pathol (2006) 2.62
Potential for treatment of liposarcomas with the MDM2 antagonist Nutlin-3A. Int J Cancer (2007) 2.52
High-resolution identification of chromosomal abnormalities using oligonucleotide arrays containing 116,204 SNPs. Am J Hum Genet (2005) 2.39
DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet (2010) 2.33
Neocentromeres: role in human disease, evolution, and centromere study. Am J Hum Genet (2002) 2.30
Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency. Medicine (Baltimore) (2010) 2.26
Building the centromere: from foundation proteins to 3D organization. Trends Cell Biol (2004) 2.15
EGFR and KRAS status of primary sarcomatoid carcinomas of the lung: implications for anti-EGFR treatment of a rare lung malignancy. Int J Cancer (2009) 2.14
Histone H3.3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells. Genome Res (2009) 2.08
Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere. Genome Res (2007) 2.03
Prospects for epigenetic epidemiology. Am J Epidemiol (2009) 2.00
Human centromere repositioning "in progress". Proc Natl Acad Sci U S A (2004) 1.88
Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR. Am J Surg Pathol (2007) 1.88
FXN methylation predicts expression and clinical outcome in Friedreich ataxia. Ann Neurol (2012) 1.83
Transcription within a functional human centromere. Mol Cell (2003) 1.77
Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence. Genome Res (2012) 1.73
LINE retrotransposon RNA is an essential structural and functional epigenetic component of a core neocentromeric chromatin. PLoS Genet (2009) 1.73
Prevalence and risk factors of the metabolic syndrome in adult survivors of childhood leukemia. Blood (2011) 1.71
Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies. Blood (2011) 1.67
Human and mouse mutations in WDR35 cause short-rib polydactyly syndromes due to abnormal ciliogenesis. Am J Hum Genet (2011) 1.66
Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor. Genes Chromosomes Cancer (2002) 1.65
Translocation-positive low-grade fibromyxoid sarcoma: clinicopathologic and molecular analysis of a series expanding the morphologic spectrum and suggesting potential relationship to sclerosing epithelioid fibrosarcoma: a study from the French Sarcoma Group. Am J Surg Pathol (2007) 1.63
Genetics of dermatofibrosarcoma protuberans family of tumors: from ring chromosomes to tyrosine kinase inhibitor treatment. Genes Chromosomes Cancer (2003) 1.61
Hyperdiploidy with 58-66 chromosomes in childhood B-acute lymphoblastic leukemia is highly curable: 58951 CLG-EORTC results. Blood (2013) 1.59
Evidence for age-related and individual-specific changes in DNA methylation profile of mononuclear cells during early immune development in humans. Epigenetics (2011) 1.55
De novo mutations in the mitochondrial ND3 gene as a cause of infantile mitochondrial encephalopathy and complex I deficiency. Ann Neurol (2004) 1.51
Dominant missense mutations in ABCC9 cause Cantú syndrome. Nat Genet (2012) 1.50
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface. J Biol Chem (2009) 1.50
Further molecular and clinical delineation of co-locating 17p13.3 microdeletions and microduplications that show distinctive phenotypes. J Med Genet (2010) 1.50
Active transcription and essential role of RNA polymerase II at the centromere during mitosis. Proc Natl Acad Sci U S A (2012) 1.50
KRAS and BRAF mutational status in primary colorectal tumors and related metastatic sites: biological and clinical implications. Ann Surg Oncol (2010) 1.48
Clustering of deletions on chromosome 13 in benign and low-malignant lipomatous tumors. Int J Cancer (2003) 1.45
HMGA2 is the partner of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon. Int J Cancer (2008) 1.44
Long-term results of the combination of the N7 induction chemotherapy and the busulfan-melphalan high dose chemotherapy. Pediatr Blood Cancer (2013) 1.43
Methylation of the filaggrin gene promoter does not affect gene expression and allergy. Pediatr Allergy Immunol (2014) 1.40
Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition. Blood (2010) 1.39
Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors. BMC Genomics (2011) 1.39
Reducing the exome search space for mendelian diseases using genetic linkage analysis of exome genotypes. Genome Biol (2011) 1.38
Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance. Genome Biol (2013) 1.36
Contrasting roles of condensin I and condensin II in mitotic chromosome formation. J Cell Sci (2012) 1.35
Clinical and biological significance of CDK4 amplification in well-differentiated and dedifferentiated liposarcomas. Clin Cancer Res (2009) 1.34
Evolutionary dynamics of transposable elements at the centromere. Trends Genet (2004) 1.33
4.45 Mb microduplication in chromosome band 14q12 including FOXG1 in a girl with refractory epilepsy and intellectual impairment. Eur J Med Genet (2009) 1.30
Archived Guthrie blood spots as a novel source for quantitative DNA methylation analysis. Biotechniques (2008) 1.30
Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated. J Biol Chem (2002) 1.27
Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation. PLoS Genet (2006) 1.26
Increased chromosome instability but not cancer predisposition in haploinsufficient Bub3 mice. Genes Chromosomes Cancer (2005) 1.25
Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns. Hum Mol Genet (2003) 1.25
Loss-of-function HDAC8 mutations cause a phenotypic spectrum of Cornelia de Lange syndrome-like features, ocular hypertelorism, large fontanelle and X-linked inheritance. Hum Mol Genet (2014) 1.25
Variable and hierarchical size distribution of L1-retroelement-enriched CENP-A clusters within a functional human neocentromere. Hum Mol Genet (2004) 1.24
Three-dimensional localization of CENP-A suggests a complex higher order structure of centromeric chromatin. J Cell Biol (2008) 1.20
Molecular cytogenetic characterization of a metastatic lung sarcomatoid carcinoma: 9p23 neocentromere and 9p23-p24 amplification including JAK2 and JMJD2C. Cancer Genet Cytogenet (2006) 1.18
Adverse obstetric and perinatal outcomes in subfertile women conceiving without assisted reproductive technologies. Fertil Steril (2010) 1.18
Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc. Hum Mol Genet (2002) 1.17
MDM2 and CDK4 immunohistochemistry is a valuable tool in the differential diagnosis of low-grade osteosarcomas and other primary fibro-osseous lesions of the bone. Mod Pathol (2011) 1.17
Tumour surveillance in Beckwith-Wiedemann syndrome and hemihyperplasia: a critical review of the evidence and suggested guidelines for local practice. J Paediatr Child Health (2006) 1.17
An exploration of genetic health professionals' experience with direct-to-consumer genetic testing in their clinical practice. Eur J Hum Genet (2012) 1.17
DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta. J Biol Chem (2010) 1.15
Increased genetic counseling support improves communication of genetic information in families. Genet Med (2008) 1.13
Targeting NF-kappaB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells. Blood (2004) 1.11
SMARCB1/INI1 inactivation in renal medullary carcinoma. Histopathology (2012) 1.10
RASA1 mutations and associated phenotypes in 68 families with capillary malformation-arteriovenous malformation. Hum Mutat (2013) 1.09
Dermatofibrosarcoma protuberans-derived fibrosarcoma: clinical history, biological profile and sensitivity to imatinib. Int J Cancer (2011) 1.08
Mutations in TRPV4 cause an inherited arthropathy of hands and feet. Nat Genet (2011) 1.07
Imatinib mesylate as a preoperative therapy in dermatofibrosarcoma: results of a multicenter phase II study on 25 patients. Clin Cancer Res (2010) 1.07
Oncocytic lipoadenoma of the parotid gland: Immunohistochemical and cytogenetic analysis. Pathol Res Pract (2009) 1.06
Low-grade extraskeletal osteosarcoma of the chest wall: case report and review of literature. BMC Cancer (2010) 1.05
A distinct DNA methylation signature defines pediatric pre-B cell acute lymphoblastic leukemia. Epigenetics (2012) 1.04
The spectrum of parathyroid gland dysfunction associated with the microdeletion 22q11. Eur J Endocrinol (2006) 1.04
11q13 alterations in two cases of hibernoma: large heterozygous deletions and rearrangement breakpoints near GARP in 11q13.5. Genes Chromosomes Cancer (2003) 1.04
The value of twins in epigenetic epidemiology. Int J Epidemiol (2012) 1.04
Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability. Genome Res (2009) 1.04
Analysis of mitotic and expression properties of human neocentromere-based transchromosomes in mice. J Biol Chem (2004) 1.04
A clinical, histologic, and molecular study of 9 cases of congenital dermatofibrosarcoma protuberans. Arch Dermatol (2007) 1.03
Wide-ranging DNA methylation differences of primary trophoblast cell populations and derived cell lines: implications and opportunities for understanding trophoblast function. Mol Hum Reprod (2011) 1.03
Maternal vitamin D predominates over genetic factors in determining neonatal circulating vitamin D concentrations. Am J Clin Nutr (2012) 1.03
Inflammatory malignant fibrous histiocytomas and dedifferentiated liposarcomas: histological review, genomic profile, and MDM2 and CDK4 status favour a single entity. J Pathol (2004) 1.02
Whole-exome sequencing identifies Coronin-1A deficiency in 3 siblings with immunodeficiency and EBV-associated B-cell lymphoproliferation. J Allergy Clin Immunol (2013) 1.00
Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitors. PLoS One (2009) 0.99
Recurrence risk in Autism Spectrum Disorder: a study of parental knowledge. J Paediatr Child Health (2007) 0.99
Extending the scope of diagnostic chromosome analysis: detection of single gene defects using high-resolution SNP microarrays. Hum Mutat (2011) 0.99
NF-kappaB inhibition triggers death of imatinib-sensitive and imatinib-resistant chronic myeloid leukemia cells including T315I Bcr-Abl mutants. Int J Cancer (2009) 0.99
Centric fission--simple and complex mechanisms. Chromosome Res (2004) 0.98
The evolutionary life cycle of the resilient centromere. Chromosoma (2012) 0.98
Partially functional Cenpa-GFP fusion protein causes increased chromosome missegregation and apoptosis during mouse embryogenesis. Chromosome Res (2003) 0.98
Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability. Cancer Res (2013) 0.97
Improved testing for CMT1A and HNPP using multiplex ligation-dependent probe amplification (MLPA) with rapid DNA preparations: comparison with the interphase FISH method. Hum Mutat (2004) 0.96
A genotype-first approach for the molecular and clinical characterization of uncommon de novo microdeletion of 20q13.33. PLoS One (2010) 0.95
Uptake of prenatal diagnostic testing and the effectiveness of prenatal screening for Down syndrome. Prenat Diagn (2010) 0.95
Cetuximab shows activity in colorectal cancer patients with tumors for which FISH analysis does not detect an increase in EGFR gene copy number. Ann Surg Oncol (2007) 0.95
No correlation between the molecular subtype of COL1A1-PDGFB fusion gene and the clinico-histopathological features of dermatofibrosarcoma protuberans. J Invest Dermatol (2009) 0.95