Published in Proc Natl Acad Sci U S A on September 05, 2007
Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex. Cell (2008) 5.87
The life and miracles of kinetochores. EMBO J (2009) 4.59
Centromeric nucleosomes induce positive DNA supercoils. Cell (2009) 4.57
Epigenetic regulation of centromeric chromatin: old dogs, new tricks? Nat Rev Genet (2008) 4.12
Molecular architecture of the kinetochore-microtubule attachment site is conserved between point and regional centromeres. J Cell Biol (2008) 2.34
Cse4 is part of an octameric nucleosome in budding yeast. Mol Cell (2009) 2.23
Epigenome characterization at single base-pair resolution. Proc Natl Acad Sci U S A (2011) 2.22
Point centromeres contain more than a single centromere-specific Cse4 (CENP-A) nucleosome. J Cell Biol (2011) 2.14
CENP-A exceeds microtubule attachment sites in centromere clusters of both budding and fission yeast. J Cell Biol (2011) 2.04
Cell-cycle-coupled structural oscillation of centromeric nucleosomes in yeast. Cell (2012) 2.02
The centromere: chromatin foundation for the kinetochore machinery. Dev Cell (2014) 2.00
Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit. Genes Dev (2009) 1.91
Structure, dynamics, and evolution of centromeric nucleosomes. Proc Natl Acad Sci U S A (2007) 1.81
Centromeres: unique chromatin structures that drive chromosome segregation. Nat Rev Mol Cell Biol (2011) 1.80
Kinetochore-microtubule interactions: the means to the end. Curr Opin Cell Biol (2008) 1.80
An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone H3 variant via the centromere targeting domain. Mol Cell (2010) 1.78
Psh1 is an E3 ubiquitin ligase that targets the centromeric histone variant Cse4. Mol Cell (2010) 1.62
Principles of chromosomal organization: lessons from yeast. J Cell Biol (2011) 1.47
Tripartite organization of centromeric chromatin in budding yeast. Proc Natl Acad Sci U S A (2011) 1.47
Structure and Scm3-mediated assembly of budding yeast centromeric nucleosomes. Nat Commun (2011) 1.46
Silent chromatin at the middle and ends: lessons from yeasts. EMBO J (2009) 1.36
Replacement of histone H3 with CENP-A directs global nucleosome array condensation and loosening of nucleosome superhelical termini. Proc Natl Acad Sci U S A (2011) 1.33
Structural and functional dissection of Mif2p, a conserved DNA-binding kinetochore protein. Mol Biol Cell (2008) 1.29
Xenopus HJURP and condensin II are required for CENP-A assembly. J Cell Biol (2011) 1.29
Function and assembly of DNA looping, clustering, and microtubule attachment complexes within a eukaryotic kinetochore. Mol Biol Cell (2009) 1.27
The quantitative architecture of centromeric chromatin. Elife (2014) 1.26
ISWI and CHD chromatin remodelers bind promoters but act in gene bodies. PLoS Genet (2013) 1.25
CENP-A: the key player behind centromere identity, propagation, and kinetochore assembly. Chromosoma (2012) 1.24
The centromeric nucleosome of budding yeast is perfectly positioned and covers the entire centromere. Proc Natl Acad Sci U S A (2011) 1.24
Centromeres convert but don't cross. PLoS Biol (2010) 1.22
Altered dosage and mislocalization of histone H3 and Cse4p lead to chromosome loss in Saccharomyces cerevisiae. Genetics (2008) 1.19
The composition, functions, and regulation of the budding yeast kinetochore. Genetics (2013) 1.15
The budding yeast point centromere associates with two Cse4 molecules during mitosis. Curr Biol (2013) 1.15
"Point" centromeres of Saccharomyces harbor single centromere-specific nucleosomes. Genetics (2012) 1.14
The rapidly evolving centromere-specific histone has stringent functional requirements in Arabidopsis thaliana. Genetics (2010) 1.13
The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4. EMBO J (2011) 1.11
A Dam1-based artificial kinetochore is sufficient to promote chromosome segregation in budding yeast. Nat Cell Biol (2009) 1.11
Functional centromeres determine the activation time of pericentric origins of DNA replication in Saccharomyces cerevisiae. PLoS Genet (2012) 1.10
Rapid evolution of Cse4p-rich centromeric DNA sequences in closely related pathogenic yeasts, Candida albicans and Candida dubliniensis. Proc Natl Acad Sci U S A (2008) 1.08
The unconventional structure of centromeric nucleosomes. Chromosoma (2012) 1.06
The centromere: epigenetic control of chromosome segregation during mitosis. Cold Spring Harb Perspect Biol (2014) 1.05
Misregulation of Scm3p/HJURP causes chromosome instability in Saccharomyces cerevisiae and human cells. PLoS Genet (2011) 1.01
Scm3 is a centromeric nucleosome assembly factor. J Biol Chem (2011) 1.01
Molecular underpinnings of centromere identity and maintenance. Trends Biochem Sci (2012) 0.99
Imaging the fate of histone Cse4 reveals de novo replacement in S phase and subsequent stable residence at centromeres. Elife (2014) 0.99
Holocentromeres are dispersed point centromeres localized at transcription factor hotspots. Elife (2014) 0.98
A role for histone H4K16 hypoacetylation in Saccharomyces cerevisiae kinetochore function. Genetics (2011) 0.97
The budding yeast Centromere DNA Element II wraps a stable Cse4 hemisome in either orientation in vivo. Elife (2014) 0.95
Histone H3-variant Cse4-induced positive DNA supercoiling in the yeast plasmid has implications for a plasmid origin of a chromosome centromere. Proc Natl Acad Sci U S A (2011) 0.94
Reconstitution of hemisomes on budding yeast centromeric DNA. Nucleic Acids Res (2013) 0.93
Histone H3 localizes to the centromeric DNA in budding yeast. PLoS Genet (2012) 0.92
A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A. J Cell Biol (2014) 0.92
Yeast cohesin complex embraces 2 micron plasmid sisters in a tri-linked catenane complex. Nucleic Acids Res (2009) 0.91
The molecular topography of silenced chromatin in Saccharomyces cerevisiae. Genes Dev (2014) 0.89
Cse4 (CenH3) association with the Saccharomyces cerevisiae plasmid partitioning locus in its native and chromosomally integrated states: implications in centromere evolution. Mol Cell Biol (2010) 0.88
SWI/SNF-like chromatin remodeling factor Fun30 supports point centromere function in S. cerevisiae. PLoS Genet (2012) 0.86
Methylation of CenH3 arginine 37 regulates kinetochore integrity and chromosome segregation. Proc Natl Acad Sci U S A (2012) 0.86
Anthracyclines induce double-strand DNA breaks at active gene promoters. Mutat Res (2015) 0.86
Centromere identity: a challenge to be faced. Mol Genet Genomics (2010) 0.85
Insights into epigenetic landscape of recombination-free regions. Chromosoma (2016) 0.82
Phosphorylation by casein kinase 2 facilitates Psh1 protein-assisted degradation of Cse4 protein. J Biol Chem (2014) 0.81
Assembling pieces of the centromere epigenetics puzzle. Epigenetics (2012) 0.80
Kinetochore function and chromosome segregation rely on critical residues in histones H3 and H4 in budding yeast. Genetics (2013) 0.80
Scm3 deposits a (Cse4-H4)2 tetramer onto DNA through a Cse4-H4 dimer intermediate. Nucleic Acids Res (2014) 0.80
The partitioning and copy number control systems of the selfish yeast plasmid: an optimized molecular design for stable persistence in host cells. Microbiol Spectr (2014) 0.79
A Molecular View of Kinetochore Assembly and Function. Biology (Basel) (2017) 0.79
Evolutionary Turnover of Kinetochore Proteins: A Ship of Theseus? Trends Cell Biol (2016) 0.79
Temporal sequence and cell cycle cues in the assembly of host factors at the yeast 2 micron plasmid partitioning locus. Nucleic Acids Res (2012) 0.79
Regulation of Budding Yeast CENP-A levels Prevents Misincorporation at Promoter Nucleosomes and Transcriptional Defects. PLoS Genet (2016) 0.78
The split personality of CENP-A nucleosomes. Cell (2012) 0.78
Reconstituting the kinetochore–microtubule interface: what, why, and how. Chromosoma (2012) 0.78
Determining absolute protein numbers by quantitative fluorescence microscopy. Methods Cell Biol (2014) 0.77
Centromeric chromatin and the pathway that drives its propagation. Biochim Biophys Acta (2011) 0.77
Genetic and epigenetic regulation of centromeres: a look at HAC formation. Chromosome Res (2015) 0.77
Synergistic Control of Kinetochore Protein Levels by Psh1 and Ubr2. PLoS Genet (2016) 0.76
Lessons learned from counting molecules: how to lure CENP-A into the kinetochore. Open Biol (2014) 0.76
CENH3-GFP: a visual marker for gametophytic and somatic ploidy determination in Arabidopsis thaliana. BMC Plant Biol (2016) 0.76
Nucleosome dynamics during chromatin remodeling in vivo. Nucleus (2016) 0.76
Structure of yeast kinetochore Ndc10 DNA-binding domain reveals unexpected evolutionary relationship to tyrosine recombinases. J Biol Chem (2012) 0.76
Association of a centromere specific nucleosome with the yeast plasmid partitioning locus: Implications beyond plasmid partitioning. Mob Genet Elements (2011) 0.76
Sue Biggins: how kinetochores keep control of mitosis. Interview by Caitlin Sedwick. J Cell Biol (2012) 0.75
SAGA DUB-Ubp8 Deubiquitylates Centromeric Histone Variant Cse4. G3 (Bethesda) (2015) 0.75
Resonance assignment of disordered protein with repetitive and overlapping sequence using combinatorial approach reveals initial structural propensities and local restrictions in the denatured state. J Biomol NMR (2016) 0.75
Structure of centromere chromatin: from nucleosome to chromosomal architecture. Chromosoma (2016) 0.75
Genome-scale identification of nucleosome positions in S. cerevisiae. Science (2005) 15.04
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. Cell (2004) 10.16
ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science (2003) 10.04
Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell (2003) 9.90
Nucleotide sequence comparisons and functional analysis of yeast centromere DNAs. Cell (1982) 7.01
Dynamics of replication-independent histone turnover in budding yeast. Science (2007) 6.41
Yeast centromere DNA is in a unique and highly ordered structure in chromosomes and small circular minichromosomes. Cell (1982) 5.49
Cse4p is a component of the core centromere of Saccharomyces cerevisiae. Cell (1998) 5.43
Conserved organization of centromeric chromatin in flies and humans. Dev Cell (2002) 5.06
A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin. PLoS Biol (2004) 5.02
Three-dimensional ultrastructural analysis of the Saccharomyces cerevisiae mitotic spindle. J Cell Biol (1995) 4.96
The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. Nat Cell Biol (2006) 4.89
A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere. Cell (1991) 4.88
Functional analysis of kinetochore assembly in Caenorhabditis elegans. J Cell Biol (2001) 4.82
Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast. Science (2000) 4.33
Structural determinants for generating centromeric chromatin. Nature (2004) 4.25
Time of replication of yeast centromeres and telomeres. Cell (1988) 4.18
Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. Nature (2006) 3.81
Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres. Cell (2004) 3.68
Molecular analysis of kinetochore-microtubule attachment in budding yeast. Cell (2001) 3.67
Nonhistone Scm3 and histones CenH3-H4 assemble the core of centromere-specific nucleosomes. Cell (2007) 3.55
Incorporation of Drosophila CID/CENP-A and CENP-C into centromeres during early embryonic anaphase. Curr Biol (2007) 3.52
Structure, function, and regulation of budding yeast kinetochores. Annu Rev Cell Dev Biol (2003) 3.32
The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. J Cell Biol (2006) 3.23
Architecture of the budding yeast kinetochore reveals a conserved molecular core. J Cell Biol (2003) 2.92
Scm3 is essential to recruit the histone h3 variant cse4 to centromeres and to maintain a functional kinetochore. Mol Cell (2007) 2.82
Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4. Proc Natl Acad Sci U S A (2004) 2.80
Centromere identity maintained by nucleosomes assembled with histone H3 containing the CENP-A targeting domain. Mol Cell (2007) 2.76
Chromatin assembly at kinetochores is uncoupled from DNA replication. J Cell Biol (2000) 2.72
Mislocalization of the Drosophila centromere-specific histone CID promotes formation of functional ectopic kinetochores. Dev Cell (2006) 2.70
Scm3, an essential Saccharomyces cerevisiae centromere protein required for G2/M progression and Cse4 localization. Proc Natl Acad Sci U S A (2007) 2.51
Histone variants: deviants? Genes Dev (2005) 2.50
Stable kinetochore-microtubule attachment constrains centromere positioning in metaphase. Curr Biol (2004) 2.48
Proteolysis contributes to the exclusive centromere localization of the yeast Cse4/CENP-A histone H3 variant. Curr Biol (2004) 2.38
Chromatin containing CENP-A and alpha-satellite DNA is a major component of the inner kinetochore plate. Curr Biol (1997) 2.30
Centromeric chromatin: what makes it unique? Curr Opin Genet Dev (2005) 2.27
Chaperone-mediated assembly of centromeric chromatin in vitro. Proc Natl Acad Sci U S A (2006) 1.98
Stretching it: putting the CEN(P-A) in centromere. Curr Opin Genet Dev (2003) 1.87
Nucleosome organization of the yeast 2-micrometer DNA plasmid: a eukaryotic minichromosome. Proc Natl Acad Sci U S A (1979) 1.86
In and out: histone variant exchange in chromatin. Trends Biochem Sci (2005) 1.81
Conservative assembly and segregation of nucleosomal histones. Cell (1977) 1.79
Kinetochore-spindle microtubule interactions during mitosis. Curr Opin Cell Biol (2005) 1.77
Loading of Arabidopsis centromeric histone CENH3 occurs mainly during G2 and requires the presence of the histone fold domain. Plant Cell (2006) 1.72
Centromere formation: from epigenetics to self-assembly. Trends Cell Biol (2006) 1.71
Centromere targeting element within the histone fold domain of Cid. Mol Cell Biol (2002) 1.64
Captivating capture: how microtubules attach to kinetochores. Curr Biol (2003) 1.62
Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell (2003) 1.48
Histone H2A is required for normal centromere function in Saccharomyces cerevisiae. EMBO J (2000) 1.45
Chromosome size and origin as determinants of the level of CENP-A incorporation into human centromeres. Chromosome Res (2004) 1.09
Assembly of new histones into nucleosomes and their distribution in replicating chromatin. Proc Natl Acad Sci U S A (1982) 0.95
Long-range oscillation in a periodic DNA sequence motif may influence nucleosome array formation. Nucleic Acids Res (2005) 0.95
The spindle checkpoint: tension versus attachment. Trends Cell Biol (2005) 3.63
The Ipl1-Aurora protein kinase activates the spindle checkpoint by creating unattached kinetochores. Nat Cell Biol (2005) 3.61
The NoCut pathway links completion of cytokinesis to spindle midzone function to prevent chromosome breakage. Cell (2006) 3.45
Tension directly stabilizes reconstituted kinetochore-microtubule attachments. Nature (2010) 2.99
Histone variants: deviants? Genes Dev (2005) 2.50
Proteolysis contributes to the exclusive centromere localization of the yeast Cse4/CENP-A histone H3 variant. Curr Biol (2004) 2.38
Mutation of YCS4, a budding yeast condensin subunit, affects mitotic and nonmitotic chromosome behavior. Mol Biol Cell (2002) 2.26
Phosphoregulation of Spc105 by Mps1 and PP1 regulates Bub1 localization to kinetochores. Curr Biol (2012) 2.00
The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. J Cell Biol (2003) 1.99
Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit. Genes Dev (2009) 1.91
An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell (2003) 1.90
An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone H3 variant via the centromere targeting domain. Mol Cell (2010) 1.78
The structure of purified kinetochores reveals multiple microtubule-attachment sites. Nat Struct Mol Biol (2012) 1.76
Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint. Genes Dev (2014) 1.65
Protein phosphatase 1 regulates exit from the spindle checkpoint in budding yeast. Curr Biol (2009) 1.61
Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7. Mol Cell Biol (2006) 1.50
A pathway containing the Ipl1/aurora protein kinase and the spindle midzone protein Ase1 regulates yeast spindle assembly. Dev Cell (2007) 1.48
Pericentromeric sister chromatid cohesion promotes kinetochore biorientation. Mol Biol Cell (2009) 1.31
De novo kinetochore assembly requires the centromeric histone H3 variant. Mol Biol Cell (2005) 1.30
Analysis of Ipl1-mediated phosphorylation of the Ndc80 kinetochore protein in Saccharomyces cerevisiae. Genetics (2009) 1.10
Phosphoregulation promotes release of kinetochores from dynamic microtubules via multiple mechanisms. Proc Natl Acad Sci U S A (2013) 0.98
Microtubule capture: a concerted effort. Cell (2006) 0.96
The overexpression of a Saccharomyces cerevisiae centromeric histone H3 variant mutant protein leads to a defect in kinetochore biorientation. Genetics (2006) 0.92
The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast. Genetics (2013) 0.88
Cdc14-dependent dephosphorylation of a kinetochore protein prior to anaphase in Saccharomyces cerevisiae. Genetics (2010) 0.87
The Mub1/Ubr2 ubiquitin ligase complex regulates the conserved Dsn1 kinetochore protein. PLoS Genet (2013) 0.86
An efficient purification system for native minichromosome from Saccharomyces cerevisiae. Methods Mol Biol (2012) 0.84
Kinetochore function and chromosome segregation rely on critical residues in histones H3 and H4 in budding yeast. Genetics (2013) 0.80
Reconstituting the kinetochore–microtubule interface: what, why, and how. Chromosoma (2012) 0.78
Top-SUMO wrestles centromeric cohesion. Dev Cell (2002) 0.77
Correcting SYNful attachments. Nat Cell Biol (2004) 0.76
Sue Biggins: how kinetochores keep control of mitosis. Interview by Caitlin Sedwick. J Cell Biol (2012) 0.75
Comment on "A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint". Science (2007) 0.75
Corrigendum: Quantitative proteomic analysis of purified yeast kinetochores identifies a PP1 regulatory subunit. Genes Dev (2016) 0.75